Effect of acute poly(ADP-ribose) polymerase inhibition by 3-AB on blood-brain barrier permeability and edema formation after focal traumatic brain injury in rats

Journal of Neurotrauma

Volumn 27, Issue 6, 2010, Pages 1069-1079

  Lescot, Thomas ^a,b   Fulla Oller, Laurence ^b,c   Palmier, Bruno ^a   Po, Christelle ^c   Beziaud, Tiphaine ^a   Puybasset, Louis ^b   Plotkine, Michel ^a   Gillet, Brigitte ^c   Meric, Philippe ^c   Marchand Leroux, Catherine ^a  

^a FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c CNRS   (France)

Author keywords

brain edema; matrix metalloproteinase; nuclear magnetic resonance; poly(ADP ribose)polymerase; traumatic brain injury

Indexed keywords

3 AMINOBENZAMIDE; CHOLINE; CREATINE; GELATINASE B; N ACETYLASPARTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; 3-AMINOBENZAMIDE; BENZAMIDE DERIVATIVE; ENZYME INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CONTROLLED STUDY; EDEMA; ENZYME INHIBITION; ENZYME REGULATION; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TRAUMATIC BRAIN INJURY; WESTERN BLOTTING; ZYMOGRAPHY; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; BRAIN EDEMA; BRAIN INJURY; DRUG EFFECTS; IMAGE PROCESSING; MALE; METABOLISM; NONPARAMETRIC TEST; PATHOLOGY; PERMEABILITY; SPRAGUE DAWLEY RAT;

ANIMALS; BENZAMIDES; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; BRAIN EDEMA; BRAIN INJURIES; ENZYME INHIBITORS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MATRIX METALLOPROTEINASE 9; PERMEABILITY; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY; STATISTICS, NONPARAMETRIC;

EID: 77953928024     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2009.1188     Document Type: Article

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