Role of interleukin-1β in early brain injury after subarachnoid hemorrhage in mice

Stroke

Volumn 40, Issue 7, 2009, Pages 2519-2525

  Sozen, Takumi ^a,c   Tsuchiyama, Reiko ^a   Hasegawa, Yu ^a   Suzuki, Hidenori ^a   Jadhav, Vikram ^a   Nishizawa, Shigeru ^c   Zhang, John H ^a,b  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Brain edema; Early brain injury; Interleukin 1 3; Neurovascular protection; Subarachnoid hemorrhage

Indexed keywords

EVANS BLUE; GELATINASE B; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; N ACETYLTYROSYLVALYLALANYLASPARTYLCHLOROMETHYLKETONE; PROTEIN ZO1; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; INTERLEUKIN-1BETA-CONVERTING ENZYME INHIBITOR; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; N ACETYL TYROSYL VALYL ALANYL ASPARTYL CHLOROMETHYL KETONE; N-ACETYL-TYROSYL-VALYL-ALANYL-ASPARTYL CHLOROMETHYL KETONE; PEPTIDE CHLOROMETHYL KETONE; PHOSPHOPROTEIN; SERINE PROTEINASE INHIBITOR; VIRUS PROTEIN; ZONULA OCCLUDENS 1 PROTEIN; ZONULA OCCLUDENS-1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL PERFORATION; BRAIN ARTERY; BRAIN EDEMA; BRAIN INJURY; BRAIN REGION; BRAIN WATER; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; ENZYME PHOSPHORYLATION; EXTRAVASATION; HISTOPATHOLOGY; LOW DRUG DOSE; MORTALITY; MOUSE; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBARACHNOID HEMORRHAGE; WESTERN BLOTTING; ANIMAL; DISEASE MODEL; HOSPITALIZATION; METABOLISM; MOUSE STRAIN; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN INJURIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; INTERLEUKIN-1BETA; MAP KINASE KINASE 4; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; MICE; MICE, INBRED STRAINS; PHOSPHOPROTEINS; SERPINS; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE; VIRAL PROTEINS;

EID: 67650064909     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.109.549592     Document Type: Article

References (27)

1. Schievink WI, Riedinger M, Jhutty TK, Simon P. Racial disparities in subarachnoid hemorrhage mortality: Los Angeles County, California, 1985-1998. Neuroepidemiology. 2004;23:299-305.
2. Cahill J, Calvert JW, Zhang JH. Mechanisms of early brain injury after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2006;26: 1341-1353.
3. Ostrowski RP, Colohan AR, Zhang JH. Molecular mechanisms of early brain injury after subarachnoid hemorrhage. Neurol Res. 2006;28: 399-414.
4. Sercombe R, Dinh YR, Gomis P. Cerebrovascular inflammation following subarachnoid hemorrhage. Jpn J Pharmacol. 2002;88:227-249.
5. McKeating EG, Andrews PJ. Cytokines and adhesion molecules in acute brain injury. Br J Anaesth. 1998;80:77-84.
6. Allan SM, Tyrrell PJ, Rothwell NJ. Interleukin-1 and neuronal injury. Nat Rev Immunol. 2005;5:629-640.
7. Prunell GF, Svendgaard NA, Alkass K, Mathiesen T. Inflammation in the brain after experimental subarachnoid hemorrhage. Neurosurgery. 2005; 56:1082-1092.
8. Kwon KY, Jeon BC. Cytokine levels in cerebrospinal fluid and delayed ischemic deficits in patients with aneurysmal subarachnoid hemorrhage. J Korean Med Sci. 2001;16:774-780.
9. Dinarello CA. Interleukin-1beta, interleukin-18, and the interleukin-1beta converting enzyme. Ann N Y Acad Sci. 1998;856:1-11.
10. Park S, Yamaguchi M, Zhou C, Calvert JW, Tang J, Zhang JH. Neuro-vascular protection reduces early brain injury after subarachnoid hemorrhage. Stroke. 2004;35:2412-2417.
11. Sugawara T, Ayer R, Jadhav V, Zhang JH. A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model. J Neurosci Methods. 2008;167:327-334.
12. Garcia JH, Wagner S, Liu KF, Hu XJ. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke. 1995;26:627- 634.
13. Ostrowski RP, Colohan AR, Zhang JH. Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2005;25:554-571.
14. Xi G, Hua Y, Bhasin RR, Ennis SR, Keep RF, Hoff JT. Mechanisms of edema formation after intracerebral hemorrhage: effects of extravasated red blood cells on blood flow and blood-brain barrier integrity. Stroke. 2001;32:2932-2938.
15. Kamath AF, Chauhan AK, Kisucka J, Dole VS, Loscalzo J, Handy DE, Wagner DD. Elevated levels of homocysteine compromise blood-brain barrier integrity in mice. Blood. 2006;107:591-593.
16. Rössner W, Tempel K. [Quantitative determination of the permeability of the so-called blood-brain barrier of Evans blue (T 1824)]. Med Pharmacol Exp Int J Exp Med. 1966;14:169-182.
17. Iseda K, Ono S, Onoda K, Satoh M, Manabe H, Nishiguchi M, Takahashi K, Tokunaga K, Sugiu K, Date I. Antivasospastic and antiinflammatory effects of caspase inhibitor in experimental subarachnoid hemorrhage. J Neurosurg. 2007;107:128-135.
18. Ruhul Amin AR, Senga T, Oo ML, Thant AA, Hamaguchi M. Secretion of matrix metalloproteinase-9 by the proinflammatory cytokine, IL-1beta: a role for the dual signaling pathways, Akt and Erk. Genes Cells. 2003; 8:515-523.
19. Vecil GG, Larsen PH, Corley SM, Herx LM, Besson A, Goodyer CG, Yong VW.Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo. J Neurosci Res. 2000;61:212-224.
20. Yong VW, Power C, Forsyth P, Edwards DR. Metalloproteinases in biology and pathology of the nervous system. Nat Rev Neurosci. 2001; 2:502-511.
21. Yang Y, Estrada EY, Thompson JF, Liu W, Rosenberg GA. Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat. J Cereb Blood Flow Metab. 2007;27: 697-709.
22. Wolburg H, Lippoldt A. Tight junctions of the blood-brain barrier: development, composition and regulation. Vascul Pharmacol. 2002;38: 323-337.
23. Kondo T, Hafezi-Moghadam A, Thomas K, Wagner DD, Kahn CR. Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier. Biochem Biophys Res Commun. 2004;317:315-320.
24. Wu CY, Hsieh HL, Jou MJ, Yang CM. Involvement of p42/p44 MAPK, p38 MAPK, JNK and nuclear factor-kappa B in interleukin-1beta-induced matrix metalloproteinase-9 expression in rat brain astrocytes. J Neu-rochem. 2004;90:1477-1488.
25. Zhang Y, Rosenberg PA. Caspase-1 and poly (ADP-ribose) polymerase inhibitors may protect against peroxynitrite-induced neurotoxicity independent of their enzyme inhibitor activity. Eur J Neurosci. 2004;20: 1727-1736.
26. Gray J, Haran MM, Schneider K, Vesce S, Ray AM, Owen D, White IR, Cutler P, Davis JB. Evidence that inhibition of cathepsin-B contributes to the neuroprotective properties of caspase inhibitor Tyr-Val-Ala-Asp-chloromethyl ketone. J Biol Chem. 2001;276:32750- 32755.
27. Ayer RE, Sugawara T, Chen W, Tong W, Zhang JH. Melatonin decreases mortality following severe subarachnoid hemorrhage. J Pineal Res. 2008; 44:197-204.