Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response, and alterations in lipid homeostasis

Toxicological Sciences

Volumn 127, Issue 2, 2012, Pages 474-484

  Bourdon, Julie A ^a   Halappanavar, Sabina ^a   Saber, Anne T ^b   Jacobsen, Nicklas R ^b   Williams, Andrew ^a   Wallin, Håkan ^b   Vogel, Ulla ^b   Yauk, Carole L ^a  

^a HEALTH CANADA   (Canada)

^b NATIONAL RESEARCH CENTRE FOR THE WORKING ENVIRONMENT   (Denmark)

Author keywords

DNA microarrays; Nanotoxicology; Systems biology

Indexed keywords

C REACTIVE PROTEIN; CARBON; CERULOPLASMIN; CHOLESTEROL; COMPLEMENT COMPONENT C3; FARNESYL TRANS TRANSFERASE; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; ISOPENTENYL DIPHOSPHATE DELTA ISOMERASE; LANOSTEROL SYNTHASE; LOW DENSITY LIPOPROTEIN; METALLOTHIONEIN II; MEVALONATE KINASE; NANOPARTICLE; OROSOMUCOID; SERUM AMYLOID A; SQUALENE MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CERULOPLASMIN BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE EXPRESSION; HOMEOSTASIS; INFLAMMATORY CELL; LIPOPROTEIN BLOOD LEVEL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PROTEIN ANALYSIS; TOXICOGENETICS;

MUS;

EID: 84861463226     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs119     Document Type: Article

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