Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver

Particle and Fibre Toxicology

Volumn 9, Issue , 2012, Pages

  Bourdon, Julie A ^a   Saber, Anne T ^b   Jacobsen, Nicklas R ^b   Jensen, Keld A ^b   Madsen, Anne M ^b   Lamson, Jacob S ^b   Wallin, Håkan ^b,c   Møller, Peter ^c   Loft, Steffen ^c   Yauk, Carole L ^a   Vogel, Ulla B ^b  

^a HEALTH CANADA   (Canada)

^b NATIONAL RESEARCH CENTRE FOR THE WORKING ENVIRONMENT   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Carbon black; Dna strand breaks; Genotoxicity; Inflammation; Nanoparticles; Oxidative stress

Indexed keywords

BLACK CARBON; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; DRUG INSTILLATION; ENVIRONMENTAL EXPOSURE; FEMALE; GENE EXPRESSION; GENOTOXICITY; HEPATITIS; INFLAMMATION; LUNG LAVAGE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PNEUMONIA; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; C57BL MOUSE; CHEMISTRY; COMET ASSAY; CYTOLOGY; DRUG EFFECT; IMMUNOLOGY; LIVER; LUNG; OCCUPATIONAL EXPOSURE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SOOT;

MUS;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; COMET ASSAY; DNA DAMAGE; FEMALE; INFLAMMATION; LIVER; LUNG; MICE; MICE, INBRED C57BL; NANOPARTICLES; OCCUPATIONAL EXPOSURE; SOOT;

EID: 84856505316     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-9-5     Document Type: Article

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