The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer’s and Huntington’s diseases

Journal of Neuroscience

Volumn 35, Issue 6, 2015, Pages 2817-2829

  Haim, Lucile Ben ^a,b   Ceyzériat, Kelly ^a,b   Sauvage, Maria Angeles Carrillo de ^a,b   Aubry, Fabien ^a,b   Auregan, Gwennaëlle ^a,b   Guillermier, Martine ^a,b   Ruiz, Marta ^a,b   Petit, Fanny ^a,b   Houitte, Diane ^a,b   Faivre, Emilie ^a,b   Vandesquille, Matthias ^a,b   Aron Badin, Romina ^a,b   Dhenain, Marc ^a,b   Déglon, Nicole ^a,b,c   Hantraye, Philippe ^a,b   Brouillet, Emmanuel ^a,b   Bonvento, Gilles ^a,b   Escartin, Carole ^a,b  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b CNRS   (France)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Animal models; Lentiviral vector; Neurodegenerative diseases; Reactive astrocytes; SOCS3; STAT3

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CYTOCHROME C OXIDASE; HUNTINGTIN; JANUS KINASE; LENTIVIRUS VECTOR; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, MOUSE; SOCS3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTE REACTIVITY; AUTOPSY; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HAPLORHINI; HUNTINGTON CHOREA; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOUSE; NERVE FUNCTION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; VESICULOVIRUS; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; GENETICS; HUMAN; MACACA FASCICULARIS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; ANIMALS; ASTROCYTES; ELECTRON TRANSPORT COMPLEX IV; HUMANS; HUNTINGTON DISEASE; JANUS KINASES; MACACA FASCICULARIS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NF-KAPPA B; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84922485980     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3516-14.2015     Document Type: Article

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