Activation of STAT3 and inhibitory effects of pioglitazone on STAT3 activity in a mouse model of SOD1-mutated amyotrophic lateral sclerosis

Neuropathology

Volumn 30, Issue 4, 2010, Pages 353-360

  Shibata, Noriyuki ^a   Yamamoto, Tomoko ^a   Hiroi, Atsuko ^a   Omi, Yoko ^a   Kato, Yoichiro ^a   Kobayashi, Makio ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

amyotrophic lateral sclerosis; neuroinflammation; signal transducer and activator of transcription; superoxide dismutase 1; transgenic mouse model

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; PIOGLITAZONE; STAT3 PROTEIN; TRANSCRIPTION FACTOR;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MICROGLIA; MOTONEURON NUCLEUS; MOTOR NEURON DISEASE; MOUSE; MUTATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURONS; MUTATION; NEUROGLIA; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PROTEIN TRANSPORT; SPINAL CORD; STAT3 TRANSCRIPTION FACTOR; SUPEROXIDE DISMUTASE; THIAZOLIDINEDIONES;

EID: 77954829973     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2009.01078.x     Document Type: Article

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