메뉴 건너뛰기




Volumn 81, Issue 2, 2014, Pages 229-248

Reactive gliosis and the multicellular response to CNS damage and disease

Author keywords

[No Author keywords available]

Indexed keywords

ASTROCYTE; AUTOIMMUNE DISEASE; BLOOD BRAIN BARRIER; CELL DAMAGE; CELL DEATH; CELL INTERACTION; CELL PROLIFERATION; CELL TYPE; CENTRAL NERVOUS SYSTEM DISEASE; CENTRAL NERVOUS SYSTEM EXTRINSIC CELL; CENTRAL NERVOUS SYSTEM INSULT; CENTRAL NERVOUS SYSTEM INTRINSIC NEURAL CELL; CENTRAL NERVOUS SYSTEM INTRINSIC NONNEURAL CELL; CHRONIC DISEASE; DEGENERATIVE DISEASE; EPILEPSY; EXTRACELLULAR MATRIX; GENE MUTATION; GENETIC POLYMORPHISM; GLIOSIS; HUMAN; INFECTION; INFLAMMATION; INTRACELLULAR SIGNALING; LEUKOCYTE MIGRATION; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; TISSUE REPAIR; TRAUMATIC BRAIN INJURY; WOUND HEALING;

EID: 84892741034     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2013.12.034     Document Type: Review
Times cited : (1061)

References (165)
  • 1
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • Abbott N.J., Rönnbäck L., Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 2006, 7:41-53.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 41-53
    • Abbott, N.J.1    Rönnbäck, L.2    Hansson, E.3
  • 2
  • 4
    • 81255214547 scopus 로고    scopus 로고
    • Central nervous system fibrosis is associated with fibrocyte-like infiltrates
    • Aldrich A., Kielian T. Central nervous system fibrosis is associated with fibrocyte-like infiltrates. Am. J. Pathol. 2011, 179:2952-2962.
    • (2011) Am. J. Pathol. , vol.179 , pp. 2952-2962
    • Aldrich, A.1    Kielian, T.2
  • 5
    • 60649108674 scopus 로고    scopus 로고
    • VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown
    • Argaw A.T., Gurfein B.T., Zhang Y., Zameer A., John G.R. VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown. Proc. Natl. Acad. Sci. USA 2009, 106:1977-1982.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 1977-1982
    • Argaw, A.T.1    Gurfein, B.T.2    Zhang, Y.3    Zameer, A.4    John, G.R.5
  • 9
    • 0019822988 scopus 로고
    • Thresholds in cerebral ischemia - the ischemic penumbra
    • Astrup J., Siesjö B.K., Symon L. Thresholds in cerebral ischemia - the ischemic penumbra. Stroke 1981, 12:723-725.
    • (1981) Stroke , vol.12 , pp. 723-725
    • Astrup, J.1    Siesjö, B.K.2    Symon, L.3
  • 13
    • 55049084760 scopus 로고    scopus 로고
    • The mystery and magic of glia: a perspective on their roles in health and disease
    • Barres B.A. The mystery and magic of glia: a perspective on their roles in health and disease. Neuron 2008, 60:430-440.
    • (2008) Neuron , vol.60 , pp. 430-440
    • Barres, B.A.1
  • 14
    • 78049279739 scopus 로고    scopus 로고
    • Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging
    • Bell R.D., Winkler E.A., Sagare A.P., Singh I., LaRue B., Deane R., Zlokovic B.V. Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging. Neuron 2010, 68:409-427.
    • (2010) Neuron , vol.68 , pp. 409-427
    • Bell, R.D.1    Winkler, E.A.2    Sagare, A.P.3    Singh, I.4    LaRue, B.5    Deane, R.6    Zlokovic, B.V.7
  • 17
    • 0034988303 scopus 로고    scopus 로고
    • Bone marrow stromal stem cells: nature, biology, and potential applications
    • Bianco P., Riminucci M., Gronthos S., Robey P.G. Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 2001, 19:180-192.
    • (2001) Stem Cells , vol.19 , pp. 180-192
    • Bianco, P.1    Riminucci, M.2    Gronthos, S.3    Robey, P.G.4
  • 18
    • 33846705350 scopus 로고    scopus 로고
    • Cell transplantation therapy for stroke
    • Bliss T., Guzman R., Daadi M., Steinberg G.K. Cell transplantation therapy for stroke. Stroke 2007, 38(Suppl):817-826.
    • (2007) Stroke , vol.38 , Issue.SUPPL. , pp. 817-826
    • Bliss, T.1    Guzman, R.2    Daadi, M.3    Steinberg, G.K.4
  • 19
    • 33749056809 scopus 로고    scopus 로고
    • ALS: a disease of motor neurons and their nonneuronal neighbors
    • Boillée S., Vande Velde C., Cleveland D.W. ALS: a disease of motor neurons and their nonneuronal neighbors. Neuron 2006, 52:39-59.
    • (2006) Neuron , vol.52 , pp. 39-59
    • Boillée, S.1    Vande Velde, C.2    Cleveland, D.W.3
  • 20
    • 22344431751 scopus 로고    scopus 로고
    • Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury
    • Brambilla R., Bracchi-Ricard V., Hu W.H., Frydel B., Bramwell A., Karmally S., Green E.J., Bethea J.R. Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury. J. Exp. Med. 2005, 202:145-156.
    • (2005) J. Exp. Med. , vol.202 , pp. 145-156
    • Brambilla, R.1    Bracchi-Ricard, V.2    Hu, W.H.3    Frydel, B.4    Bramwell, A.5    Karmally, S.6    Green, E.J.7    Bethea, J.R.8
  • 23
    • 84880818884 scopus 로고    scopus 로고
    • Critical role for PAR1 in kallikrein 6-mediated oligodendrogliopathy
    • Burda J.E., Radulovic M., Yoon H., Scarisbrick I.A. Critical role for PAR1 in kallikrein 6-mediated oligodendrogliopathy. Glia 2013, 61:1456-1470.
    • (2013) Glia , vol.61 , pp. 1456-1470
    • Burda, J.E.1    Radulovic, M.2    Yoon, H.3    Scarisbrick, I.A.4
  • 24
    • 0033152442 scopus 로고    scopus 로고
    • Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice
    • Bush T.G., Puvanachandra N., Horner C.H., Polito A., Ostenfeld T., Svendsen C.N., Mucke L., Johnson M.H., Sofroniew M.V. Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice. Neuron 1999, 23:297-308.
    • (1999) Neuron , vol.23 , pp. 297-308
    • Bush, T.G.1    Puvanachandra, N.2    Horner, C.H.3    Polito, A.4    Ostenfeld, T.5    Svendsen, C.N.6    Mucke, L.7    Johnson, M.H.8    Sofroniew, M.V.9
  • 25
    • 33646337394 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of neural repair after stroke: making waves
    • Carmichael S.T. Cellular and molecular mechanisms of neural repair after stroke: making waves. Ann. Neurol. 2006, 59:735-742.
    • (2006) Ann. Neurol. , vol.59 , pp. 735-742
    • Carmichael, S.T.1
  • 26
    • 0036144964 scopus 로고    scopus 로고
    • New vascular tissue rapidly replaces neural parenchyma and vessels destroyed by a contusion injury to the rat spinal cord
    • Casella G.T., Marcillo A., Bunge M.B., Wood P.M. New vascular tissue rapidly replaces neural parenchyma and vessels destroyed by a contusion injury to the rat spinal cord. Exp. Neurol. 2002, 173:63-76.
    • (2002) Exp. Neurol. , vol.173 , pp. 63-76
    • Casella, G.T.1    Marcillo, A.2    Bunge, M.B.3    Wood, P.M.4
  • 28
    • 78149431325 scopus 로고    scopus 로고
    • Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke
    • Clarkson A.N., Huang B.S., Macisaac S.E., Mody I., Carmichael S.T. Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke. Nature 2010, 468:305-309.
    • (2010) Nature , vol.468 , pp. 305-309
    • Clarkson, A.N.1    Huang, B.S.2    Macisaac, S.E.3    Mody, I.4    Carmichael, S.T.5
  • 29
  • 30
    • 78649487239 scopus 로고    scopus 로고
    • Pericytes are required for blood-brain barrier integrity during embryogenesis
    • Daneman R., Zhou L., Kebede A.A., Barres B.A. Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 2010, 468:562-566.
    • (2010) Nature , vol.468 , pp. 562-566
    • Daneman, R.1    Zhou, L.2    Kebede, A.A.3    Barres, B.A.4
  • 32
    • 33644683263 scopus 로고    scopus 로고
    • Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization
    • Davis G.E., Senger D.R. Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ. Res. 2005, 97:1093-1107.
    • (2005) Circ. Res. , vol.97 , pp. 1093-1107
    • Davis, G.E.1    Senger, D.R.2
  • 33
    • 84877285804 scopus 로고    scopus 로고
    • Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers
    • DeKosky S.T., Blennow K., Ikonomovic M.D., Gandy S. Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers. Nat. Rev. Neurol. 2013, 9:192-200.
    • (2013) Nat. Rev. Neurol. , vol.9 , pp. 192-200
    • DeKosky, S.T.1    Blennow, K.2    Ikonomovic, M.D.3    Gandy, S.4
  • 36
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: an integrated view
    • Dirnagl U., Iadecola C., Moskowitz M.A. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 1999, 22:391-397.
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 38
    • 51149107212 scopus 로고    scopus 로고
    • A novel purification method for CNS projection neurons leads to the identification of brain vascular cells as a source of trophic support for corticospinal motor neurons
    • Dugas J.C., Mandemakers W., Rogers M., Ibrahim A., Daneman R., Barres B.A. A novel purification method for CNS projection neurons leads to the identification of brain vascular cells as a source of trophic support for corticospinal motor neurons. J. Neurosci. 2008, 28:8294-8305.
    • (2008) J. Neurosci. , vol.28 , pp. 8294-8305
    • Dugas, J.C.1    Mandemakers, W.2    Rogers, M.3    Ibrahim, A.4    Daneman, R.5    Barres, B.A.6
  • 41
  • 42
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis-the plaque and its pathogenesis
    • Frohman E.M., Racke M.K., Raine C.S. Multiple sclerosis-the plaque and its pathogenesis. N. Engl. J. Med. 2006, 354:942-955.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 43
    • 40449101837 scopus 로고    scopus 로고
    • Endothelin-1 regulates astrocyte proliferation and reactive gliosis via a JNK/c-Jun signaling pathway
    • Gadea A., Schinelli S., Gallo V. Endothelin-1 regulates astrocyte proliferation and reactive gliosis via a JNK/c-Jun signaling pathway. J. Neurosci. 2008, 28:2394-2408.
    • (2008) J. Neurosci. , vol.28 , pp. 2394-2408
    • Gadea, A.1    Schinelli, S.2    Gallo, V.3
  • 44
    • 78751502344 scopus 로고    scopus 로고
    • HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration
    • Gao H.M., Zhou H., Zhang F., Wilson B.C., Kam W., Hong J.S. HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration. J. Neurosci. 2011, 31:1081-1092.
    • (2011) J. Neurosci. , vol.31 , pp. 1081-1092
    • Gao, H.M.1    Zhou, H.2    Zhang, F.3    Wilson, B.C.4    Kam, W.5    Hong, J.S.6
  • 45
    • 7044233126 scopus 로고    scopus 로고
    • GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain
    • Garcia A.D.R., Doan N.B., Imura T., Bush T.G., Sofroniew M.V. GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat. Neurosci. 2004, 7:1233-1241.
    • (2004) Nat. Neurosci. , vol.7 , pp. 1233-1241
    • Garcia, A.D.R.1    Doan, N.B.2    Imura, T.3    Bush, T.G.4    Sofroniew, M.V.5
  • 46
    • 69449093524 scopus 로고    scopus 로고
    • Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation
    • García-Alías G., Barkhuysen S., Buckle M., Fawcett J.W. Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation. Nat. Neurosci. 2009, 12:1145-1151.
    • (2009) Nat. Neurosci. , vol.12 , pp. 1145-1151
    • García-Alías, G.1    Barkhuysen, S.2    Buckle, M.3    Fawcett, J.W.4
  • 47
    • 84897102991 scopus 로고    scopus 로고
    • Astrocytic therapies for neuronal repair in stroke
    • Published online October 31, 2013
    • Gleichman A.J., Carmichael S.T. Astrocytic therapies for neuronal repair in stroke. Neurosci. Lett. 2013, Published online October 31, 2013. 10.1016/j.neulet.2013.10.055.
    • (2013) Neurosci. Lett.
    • Gleichman, A.J.1    Carmichael, S.T.2
  • 49
    • 84887147557 scopus 로고    scopus 로고
    • Current understanding of molecular and cellular mechanisms in fibroplasia and angiogenesis during acute wound healing
    • Greaves N.S., Ashcroft K.J., Baguneid M., Bayat A. Current understanding of molecular and cellular mechanisms in fibroplasia and angiogenesis during acute wound healing. J. Dermatol. Sci. 2013, 72:206-217.
    • (2013) J. Dermatol. Sci. , vol.72 , pp. 206-217
    • Greaves, N.S.1    Ashcroft, K.J.2    Baguneid, M.3    Bayat, A.4
  • 50
    • 80053930850 scopus 로고    scopus 로고
    • The regulation of the CNS innate immune response is vital for the restoration of tissue homeostasis (repair) after acute brain injury: a brief review
    • Griffiths M.R., Gasque P., Neal J.W. The regulation of the CNS innate immune response is vital for the restoration of tissue homeostasis (repair) after acute brain injury: a brief review. Int. J. Inflamm. 2010, 2010:151097.
    • (2010) Int. J. Inflamm. , vol.2010 , pp. 151097
    • Griffiths, M.R.1    Gasque, P.2    Neal, J.W.3
  • 52
    • 77951929051 scopus 로고    scopus 로고
    • Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior
    • Halassa M.M., Haydon P.G. Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior. Annu. Rev. Physiol. 2010, 72:335-355.
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 335-355
    • Halassa, M.M.1    Haydon, P.G.2
  • 53
    • 84867586343 scopus 로고    scopus 로고
    • Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors
    • Hamby M.E., Coppola G., Ao Y., Geschwind D.H., Khakh B.S., Sofroniew M.V. Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. J. Neurosci. 2012, 32:14489-14510.
    • (2012) J. Neurosci. , vol.32 , pp. 14489-14510
    • Hamby, M.E.1    Coppola, G.2    Ao, Y.3    Geschwind, D.H.4    Khakh, B.S.5    Sofroniew, M.V.6
  • 54
    • 77949841510 scopus 로고    scopus 로고
    • Do astrocytes really exocytose neurotransmittersα
    • Hamilton N.B., Attwell D. Do astrocytes really exocytose neurotransmittersα. Nat. Rev. Neurosci. 2010, 11:227-238.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 227-238
    • Hamilton, N.B.1    Attwell, D.2
  • 55
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch U.K., Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat. Neurosci. 2007, 10:1387-1394.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 57
    • 84860794215 scopus 로고    scopus 로고
    • Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery
    • Hayakawa K., Pham L.D., Katusic Z.S., Arai K., Lo E.H. Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery. Proc. Natl. Acad. Sci. USA 2012, 109:7505-7510.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 7505-7510
    • Hayakawa, K.1    Pham, L.D.2    Katusic, Z.S.3    Arai, K.4    Lo, E.H.5
  • 58
    • 74549135360 scopus 로고    scopus 로고
    • Long-term potentiation depends on release of D-serine from astrocytes
    • Henneberger C., Papouin T., Oliet S.H., Rusakov D.A. Long-term potentiation depends on release of D-serine from astrocytes. Nature 2010, 463:232-236.
    • (2010) Nature , vol.463 , pp. 232-236
    • Henneberger, C.1    Papouin, T.2    Oliet, S.H.3    Rusakov, D.A.4
  • 59
    • 33744544911 scopus 로고    scopus 로고
    • The collagenous wound healing scar in the injured central nervous system inhibits axonal regeneration
    • Hermanns S., Klapka N., Gasis M., Müller H.W. The collagenous wound healing scar in the injured central nervous system inhibits axonal regeneration. Adv. Exp. Med. Biol. 2006, 557:177-190.
    • (2006) Adv. Exp. Med. Biol. , vol.557 , pp. 177-190
    • Hermanns, S.1    Klapka, N.2    Gasis, M.3    Müller, H.W.4
  • 61
    • 84878529371 scopus 로고    scopus 로고
    • Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain
    • Hughes E.G., Kang S.H., Fukaya M., Bergles D.E. Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain. Nat. Neurosci. 2013, 16:668-676.
    • (2013) Nat. Neurosci. , vol.16 , pp. 668-676
    • Hughes, E.G.1    Kang, S.H.2    Fukaya, M.3    Bergles, D.E.4
  • 62
    • 38449112392 scopus 로고    scopus 로고
    • Astrocytic function and its alteration in the epileptic brain
    • Jabs R., Seifert G., Steinhäuser C. Astrocytic function and its alteration in the epileptic brain. Epilepsia 2008, 49(Suppl 2):3-12.
    • (2008) Epilepsia , vol.49 , Issue.SUPPL 2 , pp. 3-12
    • Jabs, R.1    Seifert, G.2    Steinhäuser, C.3
  • 63
    • 78649371677 scopus 로고    scopus 로고
    • Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury
    • Jackman N.A., Uliasz T.F., Hewett J.A., Hewett S.J. Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury. Glia 2010, 58:1806-1815.
    • (2010) Glia , vol.58 , pp. 1806-1815
    • Jackman, N.A.1    Uliasz, T.F.2    Hewett, J.A.3    Hewett, S.J.4
  • 65
    • 0026345228 scopus 로고
    • Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor
    • Kawaja M.D., Gage F.H. Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor. Neuron 1991, 7:1019-1030.
    • (1991) Neuron , vol.7 , pp. 1019-1030
    • Kawaja, M.D.1    Gage, F.H.2
  • 67
    • 33646554473 scopus 로고    scopus 로고
    • Collagen matrix in spinal cord injury
    • Klapka N., Müller H.W. Collagen matrix in spinal cord injury. J. Neurotrauma 2006, 23:422-435.
    • (2006) J. Neurotrauma , vol.23 , pp. 422-435
    • Klapka, N.1    Müller, H.W.2
  • 68
    • 84864449051 scopus 로고    scopus 로고
    • Cross-talk between neural stem cells and immune cells: the key to better brain repairα
    • Kokaia Z., Martino G., Schwartz M., Lindvall O. Cross-talk between neural stem cells and immune cells: the key to better brain repairα. Nat. Neurosci. 2012, 15:1078-1087.
    • (2012) Nat. Neurosci. , vol.15 , pp. 1078-1087
    • Kokaia, Z.1    Martino, G.2    Schwartz, M.3    Lindvall, O.4
  • 69
    • 41149118513 scopus 로고    scopus 로고
    • How dying cells alert the immune system to danger
    • Kono H., Rock K.L. How dying cells alert the immune system to danger. Nat. Rev. Immunol. 2008, 8:279-289.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 279-289
    • Kono, H.1    Rock, K.L.2
  • 71
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: a sensor for pathological events in the CNS
    • Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996, 19:312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 72
    • 67651036549 scopus 로고    scopus 로고
    • The glial nature of embryonic and adult neural stem cells
    • Kriegstein A., Alvarez-Buylla A. The glial nature of embryonic and adult neural stem cells. Annu. Rev. Neurosci. 2009, 32:149-184.
    • (2009) Annu. Rev. Neurosci. , vol.32 , pp. 149-184
    • Kriegstein, A.1    Alvarez-Buylla, A.2
  • 73
    • 84855967610 scopus 로고    scopus 로고
    • Does the endogenous neurogenic response alter behavioral recovery following strokeα
    • Lagace D.C. Does the endogenous neurogenic response alter behavioral recovery following strokeα. Behav. Brain Res. 2012, 227:426-432.
    • (2012) Behav. Brain Res. , vol.227 , pp. 426-432
    • Lagace, D.C.1
  • 74
    • 84892374506 scopus 로고    scopus 로고
    • Stem cell therapy for acute cerebral injury: what do we know and what will the future bringα
    • Lemmens R., Steinberg G.K. Stem cell therapy for acute cerebral injury: what do we know and what will the future bringα. Curr. Opin. Neurol. 2013, 26:617-625.
    • (2013) Curr. Opin. Neurol. , vol.26 , pp. 617-625
    • Lemmens, R.1    Steinberg, G.K.2
  • 75
    • 23944444890 scopus 로고    scopus 로고
    • IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel
    • Lennon V.A., Kryzer T.J., Pittock S.J., Verkman A.S., Hinson S.R. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J. Exp. Med. 2005, 202:473-477.
    • (2005) J. Exp. Med. , vol.202 , pp. 473-477
    • Lennon, V.A.1    Kryzer, T.J.2    Pittock, S.J.3    Verkman, A.S.4    Hinson, S.R.5
  • 78
    • 33745601099 scopus 로고    scopus 로고
    • Stem cells for the treatment of neurological disorders
    • Lindvall O., Kokaia Z. Stem cells for the treatment of neurological disorders. Nature 2006, 441:1094-1096.
    • (2006) Nature , vol.441 , pp. 1094-1096
    • Lindvall, O.1    Kokaia, Z.2
  • 80
    • 43249116466 scopus 로고    scopus 로고
    • A new penumbra: transitioning from injury into repair after stroke
    • Lo E.H. A new penumbra: transitioning from injury into repair after stroke. Nat. Med. 2008, 14:497-500.
    • (2008) Nat. Med. , vol.14 , pp. 497-500
    • Lo, E.H.1
  • 81
    • 0036935477 scopus 로고    scopus 로고
    • Cellular and molecular determinants of glial scar formation
    • Logan A., Berry M. Cellular and molecular determinants of glial scar formation. Adv. Exp. Med. Biol. 2002, 513:115-158.
    • (2002) Adv. Exp. Med. Biol. , vol.513 , pp. 115-158
    • Logan, A.1    Berry, M.2
  • 82
    • 84875928941 scopus 로고    scopus 로고
    • Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair
    • London A., Cohen M., Schwartz M. Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair. Front. Cell. Neurosci. 2013, 7:34.
    • (2013) Front. Cell. Neurosci. , vol.7 , pp. 34
    • London, A.1    Cohen, M.2    Schwartz, M.3
  • 83
    • 33645732219 scopus 로고    scopus 로고
    • Molecular pathology of malignant gliomas
    • Louis D.N. Molecular pathology of malignant gliomas. Annu. Rev. Pathol. 2006, 1:97-117.
    • (2006) Annu. Rev. Pathol. , vol.1 , pp. 97-117
    • Louis, D.N.1
  • 84
    • 0037089824 scopus 로고    scopus 로고
    • Temporal progression of angiogenesis and basal lamina deposition after contusive spinal cord injury in the adult rat
    • Loy D.N., Crawford C.H., Darnall J.B., Burke D.A., Onifer S.M., Whittemore S.R. Temporal progression of angiogenesis and basal lamina deposition after contusive spinal cord injury in the adult rat. J. Comp. Neurol. 2002, 445:308-324.
    • (2002) J. Comp. Neurol. , vol.445 , pp. 308-324
    • Loy, D.N.1    Crawford, C.H.2    Darnall, J.B.3    Burke, D.A.4    Onifer, S.M.5    Whittemore, S.R.6
  • 86
    • 0030056764 scopus 로고    scopus 로고
    • Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis
    • Lucchinetti C.F., Brück W., Rodriguez M., Lassmann H. Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis. Brain Pathol. 1996, 6:259-274.
    • (1996) Brain Pathol. , vol.6 , pp. 259-274
    • Lucchinetti, C.F.1    Brück, W.2    Rodriguez, M.3    Lassmann, H.4
  • 88
    • 33751237994 scopus 로고    scopus 로고
    • Mechanisms of Disease: astrocytes in neurodegenerative disease
    • Maragakis N.J., Rothstein J.D. Mechanisms of Disease: astrocytes in neurodegenerative disease. Nat. Clin. Pract. Neurol. 2006, 2:679-689.
    • (2006) Nat. Clin. Pract. Neurol. , vol.2 , pp. 679-689
    • Maragakis, N.J.1    Rothstein, J.D.2
  • 89
    • 33745684551 scopus 로고    scopus 로고
    • The therapeutic potential of neural stem cells
    • Martino G., Pluchino S. The therapeutic potential of neural stem cells. Nat. Rev. Neurosci. 2006, 7:395-406.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 395-406
    • Martino, G.1    Pluchino, S.2
  • 90
    • 0034329742 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disorders
    • Mattson M.P. Apoptosis in neurodegenerative disorders. Nat. Rev. Mol. Cell Biol. 2000, 1:120-129.
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 120-129
    • Mattson, M.P.1
  • 91
    • 84870540270 scopus 로고    scopus 로고
    • Energy intake and exercise as determinants of brain health and vulnerability to injury and disease
    • Mattson M.P. Energy intake and exercise as determinants of brain health and vulnerability to injury and disease. Cell Metab. 2012, 16:706-722.
    • (2012) Cell Metab. , vol.16 , pp. 706-722
    • Mattson, M.P.1
  • 95
    • 82255191977 scopus 로고    scopus 로고
    • TLR-dependent T cell activation in autoimmunity
    • Mills K.H. TLR-dependent T cell activation in autoimmunity. Nat. Rev. Immunol. 2011, 11:807-822.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 807-822
    • Mills, K.H.1
  • 96
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser D.M., Edwards J.P. Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 2008, 8:958-969.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 97
    • 33749508895 scopus 로고    scopus 로고
    • Essential protective roles of reactive astrocytes in traumatic brain injury
    • Myer D.J., Gurkoff G.G., Lee S.M., Hovda D.A., Sofroniew M.V. Essential protective roles of reactive astrocytes in traumatic brain injury. Brain 2006, 129:2761-2772.
    • (2006) Brain , vol.129 , pp. 2761-2772
    • Myer, D.J.1    Gurkoff, G.G.2    Lee, S.M.3    Hovda, D.A.4    Sofroniew, M.V.5
  • 98
    • 0037444676 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase by stretch-induced injury in astrocytes involves extracellular ATP and P2 purinergic receptors
    • Neary J.T., Kang Y., Willoughby K.A., Ellis E.F. Activation of extracellular signal-regulated kinase by stretch-induced injury in astrocytes involves extracellular ATP and P2 purinergic receptors. J. Neurosci. 2003, 23:2348-2356.
    • (2003) J. Neurosci. , vol.23 , pp. 2348-2356
    • Neary, J.T.1    Kang, Y.2    Willoughby, K.A.3    Ellis, E.F.4
  • 99
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • Nimmerjahn A., Kirchhoff F., Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005, 308:1314-1318.
    • (2005) Science , vol.308 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 100
    • 57749172539 scopus 로고    scopus 로고
    • Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity
    • Nishiyama A., Komitova M., Suzuki R., Zhu X. Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity. Nat. Rev. Neurosci. 2009, 10:9-22.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 9-22
    • Nishiyama, A.1    Komitova, M.2    Suzuki, R.3    Zhu, X.4
  • 101
    • 47549100832 scopus 로고    scopus 로고
    • Poststroke neurogenesis: emerging principles of migration and localization of immature neurons
    • Ohab J.J., Carmichael S.T. Poststroke neurogenesis: emerging principles of migration and localization of immature neurons. Neuroscientist 2008, 14:369-380.
    • (2008) Neuroscientist , vol.14 , pp. 369-380
    • Ohab, J.J.1    Carmichael, S.T.2
  • 104
    • 84862770601 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms underlying the role of blood vessels in spinal cord injury and repair
    • Oudega M. Molecular and cellular mechanisms underlying the role of blood vessels in spinal cord injury and repair. Cell Tissue Res. 2012, 349:269-288.
    • (2012) Cell Tissue Res. , vol.349 , pp. 269-288
    • Oudega, M.1
  • 106
    • 84859413635 scopus 로고    scopus 로고
    • Injectable hydrogels for central nervous system therapy
    • Pakulska M.M., Ballios B.G., Shoichet M.S. Injectable hydrogels for central nervous system therapy. Biomed. Mater. 2012, 7:024101.
    • (2012) Biomed. Mater. , vol.7 , pp. 024101
    • Pakulska, M.M.1    Ballios, B.G.2    Shoichet, M.S.3
  • 107
    • 77956230017 scopus 로고    scopus 로고
    • Contribution of systemic inflammation to chronic neurodegeneration
    • Perry V.H. Contribution of systemic inflammation to chronic neurodegeneration. Acta Neuropathol. 2010, 120:277-286.
    • (2010) Acta Neuropathol. , vol.120 , pp. 277-286
    • Perry, V.H.1
  • 108
    • 33846585119 scopus 로고    scopus 로고
    • Systemic infections and inflammation affect chronic neurodegeneration
    • Perry V.H., Cunningham C., Holmes C. Systemic infections and inflammation affect chronic neurodegeneration. Nat. Rev. Immunol. 2007, 7:161-167.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 161-167
    • Perry, V.H.1    Cunningham, C.2    Holmes, C.3
  • 111
    • 43949114888 scopus 로고    scopus 로고
    • Can the immune system be harnessed to repair the CNSα
    • Popovich P.G., Longbrake E.E. Can the immune system be harnessed to repair the CNSα. Nat. Rev. Neurosci. 2008, 9:481-493.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 481-493
    • Popovich, P.G.1    Longbrake, E.E.2
  • 114
    • 67650966680 scopus 로고    scopus 로고
    • Microglial physiology: unique stimuli, specialized responses
    • Ransohoff R.M., Perry V.H. Microglial physiology: unique stimuli, specialized responses. Annu. Rev. Immunol. 2009, 27:119-145.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 119-145
    • Ransohoff, R.M.1    Perry, V.H.2
  • 115
    • 79957624520 scopus 로고    scopus 로고
    • Fibrocytes: emerging effector cells in chronic inflammation
    • Reilkoff R.A., Bucala R., Herzog E.L. Fibrocytes: emerging effector cells in chronic inflammation. Nat. Rev. Immunol. 2011, 11:427-435.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 427-435
    • Reilkoff, R.A.1    Bucala, R.2    Herzog, E.L.3
  • 116
    • 60849093466 scopus 로고    scopus 로고
    • Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
    • Rothstein J.D. Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann. Neurol. 2009, 65(Suppl 1):S3-S9.
    • (2009) Ann. Neurol. , vol.65 , Issue.SUPPL 1
    • Rothstein, J.D.1
  • 119
    • 84875266578 scopus 로고    scopus 로고
    • CNS sterile injury: just another wound healingα
    • Shechter R., Schwartz M. CNS sterile injury: just another wound healingα. Trends Mol. Med. 2013, 19:135-143.
    • (2013) Trends Mol. Med. , vol.19 , pp. 135-143
    • Shechter, R.1    Schwartz, M.2
  • 120
    • 48549083976 scopus 로고    scopus 로고
    • Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons
    • Shigetomi E., Bowser D.N., Sofroniew M.V., Khakh B.S. Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons. J. Neurosci. 2008, 28:6659-6663.
    • (2008) J. Neurosci. , vol.28 , pp. 6659-6663
    • Shigetomi, E.1    Bowser, D.N.2    Sofroniew, M.V.3    Khakh, B.S.4
  • 121
    • 77957371582 scopus 로고    scopus 로고
    • Transient receptor potential canonical 3 (TRPC3) mediates thrombin-induced astrocyte activation and upregulates its own expression in cortical astrocytes
    • Shirakawa H., Sakimoto S., Nakao K., Sugishita A., Konno M., Iida S., Kusano A., Hashimoto E., Nakagawa T., Kaneko S. Transient receptor potential canonical 3 (TRPC3) mediates thrombin-induced astrocyte activation and upregulates its own expression in cortical astrocytes. J. Neurosci. 2010, 30:13116-13129.
    • (2010) J. Neurosci. , vol.30 , pp. 13116-13129
    • Shirakawa, H.1    Sakimoto, S.2    Nakao, K.3    Sugishita, A.4    Konno, M.5    Iida, S.6    Kusano, A.7    Hashimoto, E.8    Nakagawa, T.9    Kaneko, S.10
  • 122
    • 0742288565 scopus 로고    scopus 로고
    • Regeneration beyond the glial scar
    • Silver J., Miller J.H. Regeneration beyond the glial scar. Nat. Rev. Neurosci. 2004, 5:146-156.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 146-156
    • Silver, J.1    Miller, J.H.2
  • 123
    • 0027500128 scopus 로고
    • Immunocytochemical demonstration of early appearing astroglial structures that form boundaries and pathways along axon tracts in the fetal brain
    • Silver J., Edwards M.A., Levitt P. Immunocytochemical demonstration of early appearing astroglial structures that form boundaries and pathways along axon tracts in the fetal brain. J. Comp. Neurol. 1993, 328:415-436.
    • (1993) J. Comp. Neurol. , vol.328 , pp. 415-436
    • Silver, J.1    Edwards, M.A.2    Levitt, P.3
  • 127
    • 84861091779 scopus 로고    scopus 로고
    • Stem cells and spinal cord repair
    • Snyder E.Y., Teng Y.D. Stem cells and spinal cord repair. N. Engl. J. Med. 2012, 366:1940-1942.
    • (2012) N. Engl. J. Med. , vol.366 , pp. 1940-1942
    • Snyder, E.Y.1    Teng, Y.D.2
  • 129
    • 25144440471 scopus 로고    scopus 로고
    • Reactive astrocytes in neural repair and protection
    • Sofroniew M.V. Reactive astrocytes in neural repair and protection. Neuroscientist 2005, 11:400-407.
    • (2005) Neuroscientist , vol.11 , pp. 400-407
    • Sofroniew, M.V.1
  • 130
    • 70449678738 scopus 로고    scopus 로고
    • Molecular dissection of reactive astrogliosis and glial scar formation
    • Sofroniew M.V. Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci. 2009, 32:638-647.
    • (2009) Trends Neurosci. , vol.32 , pp. 638-647
    • Sofroniew, M.V.1
  • 131
    • 84895733280 scopus 로고    scopus 로고
    • Multiple roles for astrocytes as effectors of cytokines and inflammatory mediators
    • Published online October 8, 2013
    • Sofroniew M.V. Multiple roles for astrocytes as effectors of cytokines and inflammatory mediators. Neuroscientist 2013, Published online October 8, 2013. 10.1177/1073858413504466.
    • (2013) Neuroscientist
    • Sofroniew, M.V.1
  • 133
    • 84867141576 scopus 로고    scopus 로고
    • Sustained local delivery of bioactive nerve growth factor in the central nervous system via tunable diblock copolypeptide hydrogel depots
    • Song B., Song J., Zhang S., Anderson M.A., Ao Y., Yang C.Y., Deming T.J., Sofroniew M.V. Sustained local delivery of bioactive nerve growth factor in the central nervous system via tunable diblock copolypeptide hydrogel depots. Biomaterials 2012, 33:9105-9116.
    • (2012) Biomaterials , vol.33 , pp. 9105-9116
    • Song, B.1    Song, J.2    Zhang, S.3    Anderson, M.A.4    Ao, Y.5    Yang, C.Y.6    Deming, T.J.7    Sofroniew, M.V.8
  • 135
    • 84860338445 scopus 로고    scopus 로고
    • The complement system: an unexpected role in synaptic pruning during development and disease
    • Stephan A.H., Barres B.A., Stevens B. The complement system: an unexpected role in synaptic pruning during development and disease. Annu. Rev. Neurosci. 2012, 35:369-389.
    • (2012) Annu. Rev. Neurosci. , vol.35 , pp. 369-389
    • Stephan, A.H.1    Barres, B.A.2    Stevens, B.3
  • 137
    • 77956532031 scopus 로고    scopus 로고
    • Effects of axon degeneration on oligodendrocyte lineage cells: dorsal rhizotomy evokes a repair response while axon degeneration rostral to spinal contusion induces both repair and apoptosis
    • Sun F., Lin C.L., McTigue D., Shan X., Tovar C.A., Bresnahan J.C., Beattie M.S. Effects of axon degeneration on oligodendrocyte lineage cells: dorsal rhizotomy evokes a repair response while axon degeneration rostral to spinal contusion induces both repair and apoptosis. Glia 2010, 58:1304-1319.
    • (2010) Glia , vol.58 , pp. 1304-1319
    • Sun, F.1    Lin, C.L.2    McTigue, D.3    Shan, X.4    Tovar, C.A.5    Bresnahan, J.C.6    Beattie, M.S.7
  • 139
  • 140
    • 84877742824 scopus 로고    scopus 로고
    • Genetically encoded calcium indicators and astrocyte calcium microdomains
    • Tong X., Shigetomi E., Looger L.L., Khakh B.S. Genetically encoded calcium indicators and astrocyte calcium microdomains. Neuroscientist 2013, 19:274-291.
    • (2013) Neuroscientist , vol.19 , pp. 274-291
    • Tong, X.1    Shigetomi, E.2    Looger, L.L.3    Khakh, B.S.4
  • 141
    • 84861939633 scopus 로고    scopus 로고
    • Concepts and methods for the study of axonal regeneration in the CNS
    • Tuszynski M.H., Steward O. Concepts and methods for the study of axonal regeneration in the CNS. Neuron 2012, 74:777-791.
    • (2012) Neuron , vol.74 , pp. 777-791
    • Tuszynski, M.H.1    Steward, O.2
  • 143
    • 84859416185 scopus 로고    scopus 로고
    • Multifarious roles of sialic acids in immunity
    • Varki A., Gagneux P. Multifarious roles of sialic acids in immunity. Ann. N Y Acad. Sci. 2012, 1253:16-36.
    • (2012) Ann. N Y Acad. Sci. , vol.1253 , pp. 16-36
    • Varki, A.1    Gagneux, P.2
  • 144
  • 145
    • 23044435896 scopus 로고    scopus 로고
    • Astrocytes, from brain glue to communication elements: the revolution continues
    • Volterra A., Meldolesi J. Astrocytes, from brain glue to communication elements: the revolution continues. Nat. Rev. Neurosci. 2005, 6:626-640.
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 626-640
    • Volterra, A.1    Meldolesi, J.2
  • 146
    • 70349103383 scopus 로고    scopus 로고
    • Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS
    • Voskuhl R.R., Peterson R.S., Song B., Ao Y., Morales L.B., Tiwari-Woodruff S., Sofroniew M.V. Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS. J. Neurosci. 2009, 29:11511-11522.
    • (2009) J. Neurosci. , vol.29 , pp. 11511-11522
    • Voskuhl, R.R.1    Peterson, R.S.2    Song, B.3    Ao, Y.4    Morales, L.B.5    Tiwari-Woodruff, S.6    Sofroniew, M.V.7
  • 147
    • 80053574871 scopus 로고    scopus 로고
    • Regulatory T cells in CNS injury: the simple, the complex and the confused
    • Walsh J.T., Kipnis J. Regulatory T cells in CNS injury: the simple, the complex and the confused. Trends Mol. Med. 2011, 17:541-547.
    • (2011) Trends Mol. Med. , vol.17 , pp. 541-547
    • Walsh, J.T.1    Kipnis, J.2
  • 148
    • 84945496071 scopus 로고    scopus 로고
    • The perineuronal net and the control of CNS plasticity
    • Wang D., Fawcett J. The perineuronal net and the control of CNS plasticity. Cell Tissue Res. 2012, 349:147-160.
    • (2012) Cell Tissue Res. , vol.349 , pp. 147-160
    • Wang, D.1    Fawcett, J.2
  • 149
    • 84880851472 scopus 로고    scopus 로고
    • Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury
    • Wanner I.B., Anderson M.A., Song B., Levine J., Fernandez A., Gray-Thompson Z., Ao Y., Sofroniew M.V. Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury. J. Neurosci. 2013, 33:12870-12886.
    • (2013) J. Neurosci. , vol.33 , pp. 12870-12886
    • Wanner, I.B.1    Anderson, M.A.2    Song, B.3    Levine, J.4    Fernandez, A.5    Gray-Thompson, Z.6    Ao, Y.7    Sofroniew, M.V.8
  • 150
    • 84865546363 scopus 로고    scopus 로고
    • Unique biology of gliomas: challenges and opportunities
    • Watkins S., Sontheimer H. Unique biology of gliomas: challenges and opportunities. Trends Neurosci. 2012, 35:546-556.
    • (2012) Trends Neurosci. , vol.35 , pp. 546-556
    • Watkins, S.1    Sontheimer, H.2
  • 152
    • 84921776884 scopus 로고    scopus 로고
    • Permissive Schwann Cell Graft/Spinal Cord Interfaces for Axon Regeneration
    • Published online October 22, 2013
    • Williams R.R., Henao M., Pearse D.D., Bunge M.B. Permissive Schwann Cell Graft/Spinal Cord Interfaces for Axon Regeneration. Cell Transplant. 2013, Published online October 22, 2013. 10.3727/096368913X674657.
    • (2013) Cell Transplant.
    • Williams, R.R.1    Henao, M.2    Pearse, D.D.3    Bunge, M.B.4
  • 153
    • 80055014830 scopus 로고    scopus 로고
    • Central nervous system pericytes in health and disease
    • Winkler E.A., Bell R.D., Zlokovic B.V. Central nervous system pericytes in health and disease. Nat. Neurosci. 2011, 14:1398-1405.
    • (2011) Nat. Neurosci. , vol.14 , pp. 1398-1405
    • Winkler, E.A.1    Bell, R.D.2    Zlokovic, B.V.3
  • 158
    • 77955672117 scopus 로고    scopus 로고
    • Suppression of fibrotic scar formation promotes axonal regeneration without disturbing blood-brain barrier repair and withdrawal of leukocytes after traumatic brain injury
    • Yoshioka N., Hisanaga S., Kawano H. Suppression of fibrotic scar formation promotes axonal regeneration without disturbing blood-brain barrier repair and withdrawal of leukocytes after traumatic brain injury. J. Comp. Neurol. 2010, 518:3867-3881.
    • (2010) J. Comp. Neurol. , vol.518 , pp. 3867-3881
    • Yoshioka, N.1    Hisanaga, S.2    Kawano, H.3
  • 160
    • 84890178483 scopus 로고    scopus 로고
    • Tunable diblock copolypeptide hydrogel depots for local delivery of hydrophobic molecules in healthy and injured central nervous system
    • Zhang S., Anderson M.A., Ao Y., Khakh B.S., Fan J., Deming T.J., Sofroniew M.V. Tunable diblock copolypeptide hydrogel depots for local delivery of hydrophobic molecules in healthy and injured central nervous system. Biomaterials 2014, 35:1989-2000.
    • (2014) Biomaterials , vol.35 , pp. 1989-2000
    • Zhang, S.1    Anderson, M.A.2    Ao, Y.3    Khakh, B.S.4    Fan, J.5    Deming, T.J.6    Sofroniew, M.V.7
  • 161
    • 78650981570 scopus 로고    scopus 로고
    • Purinergic receptor stimulation reduces cytotoxic edema and brain infarcts in mouse induced by photothrombosis by energizing glial mitochondria
    • Zheng W., Watts L.T., Holstein D.M., Prajapati S.I., Keller C., Grass E.H., Walter C.A., Lechleiter J.D. Purinergic receptor stimulation reduces cytotoxic edema and brain infarcts in mouse induced by photothrombosis by energizing glial mitochondria. PLoS ONE 2010, 5:e14401.
    • (2010) PLoS ONE , vol.5
    • Zheng, W.1    Watts, L.T.2    Holstein, D.M.3    Prajapati, S.I.4    Keller, C.5    Grass, E.H.6    Walter, C.A.7    Lechleiter, J.D.8
  • 163
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegenerative disorders
    • Zlokovic B.V. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 2008, 57:178-201.
    • (2008) Neuron , vol.57 , pp. 178-201
    • Zlokovic, B.V.1
  • 164
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
    • Zlokovic B.V. Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat. Rev. Neurosci. 2011, 12:723-738.
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 723-738
    • Zlokovic, B.V.1
  • 165
    • 84884545941 scopus 로고    scopus 로고
    • Short hairpin RNA against PTEN enhances regenerative growth of corticospinal tract axons after spinal cord injury
    • Zukor K., Belin S., Wang C., Keelan N., Wang X., He Z. Short hairpin RNA against PTEN enhances regenerative growth of corticospinal tract axons after spinal cord injury. J. Neurosci. 2013, 33:15350-15361.
    • (2013) J. Neurosci. , vol.33 , pp. 15350-15361
    • Zukor, K.1    Belin, S.2    Wang, C.3    Keelan, N.4    Wang, X.5    He, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.