Hexosamine pathway metabolites enhance protein quality control and prolong life

Cell

Volumn 156, Issue 6, 2014, Pages 1167-1178

  Denzel, Martin S ^a   Storm, Nadia J ^a   Gutschmidt, Aljona ^c   Baddi, Ruth ^a   Hinze, Yvonne ^a   Jarosch, Ernst ^d   Sommer, Thomas ^d,e   Hoppe, Thorsten ^c   Antebi, Adam ^a,b,c  

^a MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF COLOGNE   (Germany)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^e HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HEXOSAMINE; MEMBRANE PROTEIN; N ACETYLGLUCOSAMINE; GLYCAN;

AGING; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; LIFE EXTENSION; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN HOMEOSTASIS; PROTEIN PROCESSING; PROTEIN QUALITY; PROTEIN SYNTHESIS; CULTURE MEDIUM; QUALITY CONTROL; SUPPLEMENTATION; SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; AUTOPHAGY; BIOSYNTHETIC PATHWAYS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GLUTAMINE-FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING); HEXOSAMINES; HUMANS; LONGEVITY; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BIOSYNTHESIS; PROTEINS; SEQUENCE ALIGNMENT; TUNICAMYCIN;

EID: 84896351253     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.01.061     Document Type: Article

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