-
1
-
-
78649336706
-
The DNA damage response: Making it safe to play with knives
-
Ciccia, A. And Elledge, S. J. (2010) The DNA damage response: making it safe to play with knives. Mol. Cell, 40, 179-204.
-
(2010)
Mol. Cell
, vol.40
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
2
-
-
41149094512
-
Regulation of DNA repair throughout the cell cycle
-
Branzei, D. And Foiani, M. (2008) Regulation of DNA repair throughout the cell cycle. Nat. Rev. Mol. Cell Biol., 9, 297-308.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 297-308
-
-
Branzei, D.1
Foiani, M.2
-
3
-
-
33845991538
-
RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint
-
Olson, E., Nievera, C. J., Klimovich, V., Fanning, E. And Wu, X. (2006) RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint. J. Biol. Chem., 281, 39517-39533.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 39517-39533
-
-
Olson, E.1
Nievera, C.J.2
Klimovich, V.3
Fanning, E.4
Wu, X.5
-
4
-
-
47749141560
-
ATR: An essential regulator of genome integrity
-
Cimprich, K. A. And Cortez, D. (2008) ATR: An essential regulator of genome integrity. Nat. Rev. Mol. Cell Biol., 9, 616-627.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
5
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications
-
Polo, S. E. And Jackson, S. P. (2011) Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications. Genes Dev., 25, 409-433.
-
(2011)
Genes Dev.
, vol.25
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
6
-
-
84891301320
-
Causes and consequences of replication stress
-
Zeman, M. K. And Cimprich, K. A. (2014) Causes and consequences of replication stress. Nat. Cell Biol., 16, 2-9.
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 2-9
-
-
Zeman, M.K.1
Cimprich, K.A.2
-
7
-
-
0029786013
-
Recognition of DNA by designed ligands at subnanomolar concentrations
-
Trauger, J. W., Baird, E. E. And Dervan, P. B. (1996) Recognition of DNA by designed ligands at subnanomolar concentrations. Nature, 382, 559-561.
-
(1996)
Nature
, vol.382
, pp. 559-561
-
-
Trauger, J.W.1
Baird, E.E.2
Dervan, P.B.3
-
8
-
-
0032576722
-
Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands
-
White, S., Szewczyk, J. W., Turner, J. M., Baird, E. E. And Dervan, P. B. (1998) Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands. Nature, 391, 468-471.
-
(1998)
Nature
, vol.391
, pp. 468-471
-
-
White, S.1
Szewczyk, J.W.2
Turner, J.M.3
Baird, E.E.4
Dervan, P.B.5
-
9
-
-
77958046177
-
Structural basis for cyclic Py-Im polyamide allosteric inhibition of nuclear receptor binding
-
Chenoweth, D. M. And Dervan, P. B. (2010) Structural basis for cyclic Py-Im polyamide allosteric inhibition of nuclear receptor binding. J. Am. Chem. Soc., 132, 14521-14529.
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 14521-14529
-
-
Chenoweth, D.M.1
Dervan, P.B.2
-
10
-
-
3042845814
-
Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates
-
Edelson, B. S., Best, T. P., Olenyuk, B., Nickols, N. G., Doss, R. M., Foister, S., Heckel, A. And Dervan, P. B. (2004) Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates. Nucleic Acids Res., 32, 2802-2818.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 2802-2818
-
-
Edelson, B.S.1
Best, T.P.2
Olenyuk, B.3
Nickols, N.G.4
Doss, R.M.5
Foister, S.6
Heckel, A.7
Dervan, P.B.8
-
11
-
-
0017645932
-
Specific interactions of distamycin A and its analogs with (A-T) rich and (G-C) rich duplex regions of DNA and deoxypolynucleotides
-
Luck, G., Zimmer, C., Reinert, K. E. And Arcamone, F. (1977) Specific interactions of distamycin A and its analogs with (A-T) rich and (G-C) rich duplex regions of DNA and deoxypolynucleotides. Nucleic Acids Res., 4, 2655-2670.
-
(1977)
Nucleic Acids Res.
, vol.4
, pp. 2655-2670
-
-
Luck, G.1
Zimmer, C.2
Reinert, K.E.3
Arcamone, F.4
-
12
-
-
0037334122
-
Synthesis and growth inhibition activity of alpha-bromoacrylic heterocyclic and benzoheterocyclic derivatives of distamycin A modified on the amidino moiety
-
Baraldi, P. G., Beria, I., Cozzi, P., Bianchi, N., Gambari, R. And Romagnoli, R. (2003) Synthesis and growth inhibition activity of alpha-bromoacrylic heterocyclic and benzoheterocyclic derivatives of distamycin A modified on the amidino moiety. Bioorg. Med. Chem., 11, 965-975.
-
(2003)
Bioorg. Med. Chem.
, vol.11
, pp. 965-975
-
-
Baraldi, P.G.1
Beria, I.2
Cozzi, P.3
Bianchi, N.4
Gambari, R.5
Romagnoli, R.6
-
13
-
-
0015244503
-
Influence of netropsin and distamycin A on the secondary structure and template activity of DNA
-
Zimmer, C., Puschendorf, B., Grunicke, H., Chandra, P. And Venner, H. (1971) Influence of netropsin and distamycin A on the secondary structure and template activity of DNA. Eur. J. Biochem., 21, 269-278.
-
(1971)
Eur. J. Biochem.
, vol.21
, pp. 269-278
-
-
Zimmer, C.1
Puschendorf, B.2
Grunicke, H.3
Chandra, P.4
Venner, H.5
-
14
-
-
0026585888
-
Effects of analogs of the DNA minor groove binder Hoechst-33258 on Topoisomerase-II and Topoisomerase-I mediated activities
-
Beerman, T. A., McHugh, M. M., Sigmund, R., Lown, J. W., Rao, K. E. And Bathini, Y. (1992) Effects of analogs of the DNA minor groove binder Hoechst-33258 on Topoisomerase-II and Topoisomerase-I mediated activities. Biochim. Biophys. Acta, 1131, 53-61.
-
(1992)
Biochim. Biophys. Acta
, vol.1131
, pp. 53-61
-
-
Beerman, T.A.1
McHugh, M.M.2
Sigmund, R.3
Lown, J.W.4
Rao, K.E.5
Bathini, Y.6
-
15
-
-
0343091571
-
Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs
-
Brosh, R. M. Jr, Karow, J. K., White, E. J., Shaw, N. D., Hickson, I. D. And Bohr, V. A. (2000) Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs. Nucleic Acids Res., 28, 2420-2430.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2420-2430
-
-
Brosh, R.M.1
Karow, J.K.2
White, E.J.3
Shaw, N.D.4
Hickson, I.D.5
Bohr, V.A.6
-
16
-
-
34547496561
-
Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide
-
Nickols, N. G. And Dervan, P. B. (2007) Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide. Proc. Natl Acad. Sci. U.S.A., 104, 10418-10423.
-
(2007)
Proc. Natl Acad. Sci. U.S.A.
, vol.104
, pp. 10418-10423
-
-
Nickols, N.G.1
Dervan, P.B.2
-
17
-
-
84873150881
-
Antitumor activity of a pyrrole-imidazole polyamide
-
Yang, F., Nickols, N. G., Li, B. C., Marinov, G. K., Said, J. W. And Dervan, P. B. (2013) Antitumor activity of a pyrrole-imidazole polyamide. Proc. Natl Acad. Sci. U.S.A., 110, 1863-1868.
-
(2013)
Proc. Natl Acad. Sci. U.S.A.
, vol.110
, pp. 1863-1868
-
-
Yang, F.1
Nickols, N.G.2
Li, B.C.3
Marinov, G.K.4
Said, J.W.5
Dervan, P.B.6
-
18
-
-
0036280321
-
Solid-phase synthesis of DNA binding polyamides on oxime resin
-
Belitsky, J. M., Nguyen, D. H., Wurtz, N. R. And Dervan, P. B. (2002) Solid-phase synthesis of DNA binding polyamides on oxime resin. Bioorg. Med. Chem., 10, 2767-2774.
-
(2002)
Bioorg. Med. Chem.
, vol.10
, pp. 2767-2774
-
-
Belitsky, J.M.1
Nguyen, D.H.2
Wurtz, N.R.3
Dervan, P.B.4
-
19
-
-
34347230544
-
Sulforhodamine B colorimetric assay for cytotoxicity screening
-
Vichai, V. And Kirtikara, K. (2006) Sulforhodamine B colorimetric assay for cytotoxicity screening. Nat. Protoc., 1, 1112-1116.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 1112-1116
-
-
Vichai, V.1
Kirtikara, K.2
-
20
-
-
0027249291
-
A new sulfonated tetrazolium salt that produces a highly water-soluble formazan dye
-
Ishiyama, M., Shiga, M., Sasamoto, K., Mizoguchi, M. And He, P. G. (1993) A new sulfonated tetrazolium salt that produces a highly water-soluble formazan dye. Chem. Pharm. Bull. (Tokyo), 41, 1118-1122.
-
(1993)
Chem. Pharm. Bull. (Tokyo)
, vol.41
, pp. 1118-1122
-
-
Ishiyama, M.1
Shiga, M.2
Sasamoto, K.3
Mizoguchi, M.4
He, P.G.5
-
21
-
-
79952127438
-
Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress
-
Aggarwal, M., Sommers, J. A., Shoemaker, R. H. And Brosh, R. M. Jr (2011) Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stresS. Proc. Natl Acad. Sci. U.S.A., 108, 1525-1530.
-
(2011)
Proc. Natl Acad. Sci. U.S.A.
, vol.108
, pp. 1525-1530
-
-
Aggarwal, M.1
Sommers, J.A.2
Shoemaker, R.H.3
Brosh, R.M.4
-
22
-
-
0037080675
-
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
-
Zou, L., Cortez, D. And Elledge, S. J. (2002) Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes Dev., 16, 198-208.
-
(2002)
Genes Dev.
, vol.16
, pp. 198-208
-
-
Zou, L.1
Cortez, D.2
Elledge, S.J.3
-
23
-
-
80053188747
-
Coupling dTTP hydrolysis with DNA unwinding by the DNA helicase of bacteriophage T7
-
Satapathy, A. K., Kulczyk, A. W., Ghosh, S., van Oijen, A. M. And Richardson, C. C. (2011) Coupling dTTP hydrolysis with DNA unwinding by the DNA helicase of bacteriophage T7. J. Biol. Chem., 286, 34468-34478.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 34468-34478
-
-
Satapathy, A.K.1
Kulczyk, A.W.2
Ghosh, S.3
Van Oijen, A.M.4
Richardson, C.C.5
-
24
-
-
79959913882
-
Characterization of the endonuclease and ATP-dependent flap endo/exonuclease of Dna2
-
Fortini, B. K., Pokharel, S., Polaczek, P., Balakrishnan, L., Bambara, R. A. And Campbell, J. L. (2011) Characterization of the endonuclease and ATP-dependent flap endo/exonuclease of Dna2. J. Biol. Chem., 286, 23763-23770.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 23763-23770
-
-
Fortini, B.K.1
Pokharel, S.2
Polaczek, P.3
Balakrishnan, L.4
Bambara, R.A.5
Campbell, J.L.6
-
25
-
-
84869485349
-
DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network
-
Karanja, K. K., Cox, S. W., Duxin, J. P., Stewart, S. A. And Campbell, J. L. (2012) DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network. Cell cycle, 11, 3983-3996.
-
(2012)
Cell Cycle
, vol.11
, pp. 3983-3996
-
-
Karanja, K.K.1
Cox, S.W.2
Duxin, J.P.3
Stewart, S.A.4
Campbell, J.L.5
-
26
-
-
0027056581
-
A consensus DNA-binding site for the androgen receptor
-
Roche, P. J., Hoare, S. A. And Parker, M. G. (1992) A consensus DNA-binding site for the androgen receptor. Mol. Endocrinol., 6, 2229-2235.
-
(1992)
Mol. Endocrinol.
, vol.6
, pp. 2229-2235
-
-
Roche, P.J.1
Hoare, S.A.2
Parker, M.G.3
-
27
-
-
70149095918
-
Cyclic pyrrole-imidazole polyamides targeted to the androgen response element
-
Chenoweth, D. M., Harki, D. A., Phillips, J. W., Dose, C. And Dervan, P. B. (2009) Cyclic pyrrole-imidazole polyamides targeted to the androgen response element. J. Am. Chem. Soc., 131, 7182-7188.
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 7182-7188
-
-
Chenoweth, D.M.1
Harki, D.A.2
Phillips, J.W.3
Dose, C.4
Dervan, P.B.5
-
28
-
-
33747880070
-
Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins
-
Xu, Y. Y., Chen, S. Y., Ross, K. N. And Balk, S. P. (2006) Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins. Cancer Res., 66, 7783-7792.
-
(2006)
Cancer Res.
, vol.66
, pp. 7783-7792
-
-
Xu, Y.Y.1
Chen, S.Y.2
Ross, K.N.3
Balk, S.P.4
-
29
-
-
33646417329
-
DU-145 and PC-3 human prostate cancer cell lines express androgen receptor: Implications for the androgen receptor functions and regulation
-
Alimirah, F., Chen, J., Basrawala, Z., Xin, H. And Choubey, D. (2006) DU-145 and PC-3 human prostate cancer cell lines express androgen receptor: implications for the androgen receptor functions and regulation. FEBS Lett., 580, 2294-2300.
-
(2006)
FEBS Lett.
, vol.580
, pp. 2294-2300
-
-
Alimirah, F.1
Chen, J.2
Basrawala, Z.3
Xin, H.4
Choubey, D.5
-
30
-
-
27144491909
-
Nuclear dynamics of PCNA in DNA replication and repair
-
Essers, J., Theil, A. F., Baldeyron, C., van Cappellen, W. A., Houtsmuller, A. B., Kanaar, R. And Vermeulen, W. (2005) Nuclear dynamics of PCNA in DNA replication and repair. Mol. Cell. Biol., 25, 9350-9359.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9350-9359
-
-
Essers, J.1
Theil, A.F.2
Baldeyron, C.3
Van Cappellen, W.A.4
Houtsmuller, A.B.5
Kanaar, R.6
Vermeulen, W.7
-
31
-
-
80051678503
-
Thr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase
-
Nam, E. A., Zhao, R. X., Glick, G. G., Bansbach, C. E., Friedman, D. B. And Cortez, D. (2011) Thr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase. J. Biol. Chem., 286, 28707-28714.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28707-28714
-
-
Nam, E.A.1
Zhao, R.X.2
Glick, G.G.3
Bansbach, C.E.4
Friedman, D.B.5
Cortez, D.6
-
32
-
-
79960467426
-
ATR autophosphorylation as a molecular switch for checkpoint activation
-
Liu, S. Z., Shiotani, B., Lahiri, M., Marechal, A., Tse, A., Leung, C. C. Y., Glover, J. N. M., Yang, X. H. H. And Zou, L. (2011) ATR autophosphorylation as a molecular switch for checkpoint activation. Mol. Cell, 43, 192-202.
-
(2011)
Mol. Cell
, vol.43
, pp. 192-202
-
-
Liu, S.Z.1
Shiotani, B.2
Lahiri, M.3
Marechal, A.4
Tse, A.5
Leung, C.C.Y.6
Glover, J.N.M.7
Yang, X.H.H.8
Zou, L.9
-
33
-
-
79960834396
-
Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines
-
Peasland, A., Wang, L. Z., Rowling, E., Kyle, S., Chen, T., Hopkins, A., Cliby, W. A., Sarkaria, J., Beale, G., Edmondson, R. J. et al. (2011) Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines. Br. J. Cancer, 105, 372-381.
-
(2011)
Br. J. Cancer
, vol.105
, pp. 372-381
-
-
Peasland, A.1
Wang, L.Z.2
Rowling, E.3
Kyle, S.4
Chen, T.5
Hopkins, A.6
Cliby, W.A.7
Sarkaria, J.8
Beale, G.9
Edmondson, R.J.10
-
34
-
-
76149146422
-
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
-
So, S. R., Davis, A. J. And Chen, D. J. (2009) Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites. J. Cell Biol., 187, 977-990.
-
(2009)
J. Cell Biol.
, vol.187
, pp. 977-990
-
-
So, S.R.1
Davis, A.J.2
Chen, D.J.3
-
35
-
-
0035927713
-
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses
-
Bao, S. D., Tibbetts, R. S., Brumbaugh, K. M., Fang, Y. N., Richardson, D. A., Ali, A., Chen, S. M., Abraham, R. T. And Wang, X. F. (2001) ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature, 411, 969-974.
-
(2001)
Nature
, vol.411
, pp. 969-974
-
-
Bao, S.D.1
Tibbetts, R.S.2
Brumbaugh, K.M.3
Fang, Y.N.4
Richardson, D.A.5
Ali, A.6
Chen, S.M.7
Abraham, R.T.8
Wang, X.F.9
-
36
-
-
79953183356
-
Autophosphorylation and ATM activation: Additional sites add to the complexity
-
Kozlov, S. V., Graham, M. E., Jakob, B., Tobias, F., Kijas, A. W., Tanuji, M., Chen, P., Robinson, P. J., Taucher-Scholz, G., Suzuki, K. et al. (2011) Autophosphorylation and ATM activation: Additional sites add to the complexity. J. Biol. Chem., 286, 9107-9119.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 9107-9119
-
-
Kozlov, S.V.1
Graham, M.E.2
Jakob, B.3
Tobias, F.4
Kijas, A.W.5
Tanuji, M.6
Chen, P.7
Robinson, P.J.8
Taucher-Scholz, G.9
Suzuki, K.10
-
37
-
-
9744271049
-
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
-
Hickson, I., Zhao, Y., Richardson, C. J., Green, S. J., Martin, N. M., Orr, A. I., Reaper, P. M., Jackson, S. P., Curtin, N. J. And Smith, G. C. (2004) Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res., 64, 9152-9159.
-
(2004)
Cancer Res.
, vol.64
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
Green, S.J.4
Martin, N.M.5
Orr, A.I.6
Reaper, P.M.7
Jackson, S.P.8
Curtin, N.J.9
Smith, G.C.10
-
38
-
-
84868213765
-
Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress
-
Liu, S. Q., Opiyo, S. O., Manthey, K., Glanzer, J. G., Ashley, A. K., Amerin, C., Troksa, K., Shrivastav, M., Nickoloff, J. A. And Oakley, G. G. (2012) Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress. Nucleic Acids Res., 40, 10780-10794.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 10780-10794
-
-
Liu, S.Q.1
Opiyo, S.O.2
Manthey, K.3
Glanzer, J.G.4
Ashley, A.K.5
Amerin, C.6
Troksa, K.7
Shrivastav, M.8
Nickoloff, J.A.9
Oakley, G.G.10
-
39
-
-
84868599554
-
DNA damage-induced CHK1 autophosphorylation at Ser296 is regulated by an intramolecular mechanism
-
Okita, N., Minato, S., Ohmi, E., Tanuma, S. And Higami, Y. (2012) DNA damage-induced CHK1 autophosphorylation at Ser296 is regulated by an intramolecular mechanism. FEBS Lett., 586, 3974-3979.
-
(2012)
FEBS Lett.
, vol.586
, pp. 3974-3979
-
-
Okita, N.1
Minato, S.2
Ohmi, E.3
Tanuma, S.4
Higami, Y.5
-
40
-
-
70849110242
-
Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress
-
Vassin, V. M., Anantha, R. W., Sokolova, E., Kanner, S. And Borowiec, J. A. (2009) Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress. J. Cell Sci., 122, 4070-4080.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 4070-4080
-
-
Vassin, V.M.1
Anantha, R.W.2
Sokolova, E.3
Kanner, S.4
Borowiec, J.A.5
-
41
-
-
0035930536
-
Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks
-
Ward, I. M., Wu, X. L. And Chen, J. J. (2001) Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks. J. Biol. Chem., 276, 47755-47758.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47755-47758
-
-
Ward, I.M.1
Wu, X.L.2
Chen, J.J.3
-
42
-
-
44249118962
-
ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis
-
Pabla, N., Huang, S., Mi, Q. S., Daniel, R. And Dong, Z. (2008) ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. J. Biol. Chem., 283, 6572-6583.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 6572-6583
-
-
Pabla, N.1
Huang, S.2
Mi, Q.S.3
Daniel, R.4
Dong, Z.5
-
43
-
-
79959629469
-
Analysis of protein dynamics at active, stalled, and collapsed replication forks
-
Sirbu, B. M., Couch, F. B., Feigerle, J. T., Bhaskara, S., Hiebert, S. W. And Cortez, D. (2011) Analysis of protein dynamics at active, stalled, and collapsed replication forks. Genes Dev., 25, 1320-1327.
-
(2011)
Genes Dev.
, vol.25
, pp. 1320-1327
-
-
Sirbu, B.M.1
Couch, F.B.2
Feigerle, J.T.3
Bhaskara, S.4
Hiebert, S.W.5
Cortez, D.6
-
44
-
-
66349084196
-
H2AX is required for cell cycle arrest via the p53/p21 pathway
-
Fragkos, M., Jurvansuu, J. And Beard, P. (2009) H2AX is required for cell cycle arrest via the p53/p21 pathway. Mol. Cell. Biol., 29, 2828-2840.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 2828-2840
-
-
Fragkos, M.1
Jurvansuu, J.2
Beard, P.3
-
45
-
-
11144227916
-
Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses
-
Yoo, H. Y., Shevchenko, A. And Dunphy, W. G. (2004) Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses. J. Biol. Chem., 279, 53353-53364.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 53353-53364
-
-
Yoo, H.Y.1
Shevchenko, A.2
Dunphy, W.G.3
-
46
-
-
40949133430
-
Plx1 is required for chromosomal DNA replication under stressful conditions
-
Trenz, K., Errico, A. And Costanzo, V. (2008) Plx1 is required for chromosomal DNA replication under stressful conditions. EMBO J., 27, 876-885.
-
(2008)
EMBO J.
, vol.27
, pp. 876-885
-
-
Trenz, K.1
Errico, A.2
Costanzo, V.3
-
47
-
-
84883780177
-
FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling
-
Lossaint, G., Larroque, M., Ribeyre, C., Bec, N., Larroque, C., Decaillet, C., Gari, K. And Constantinou, A. (2013) FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling. Mol. Cell, 51, 678-690.
-
(2013)
Mol. Cell
, vol.51
, pp. 678-690
-
-
Lossaint, G.1
Larroque, M.2
Ribeyre, C.3
Bec, N.4
Larroque, C.5
Decaillet, C.6
Gari, K.7
Constantinou, A.8
-
48
-
-
84863244765
-
ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway
-
Shigechi, T., Tomida, J., Sato, K., Kobayashi, M., Eykelenboom, J. K., Pessina, F., Zhang, Y., Uchida, E., Ishiai, M., Lowndes, N. F. et al. (2012) ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway. Cancer Res., 72, 1149-1156.
-
(2012)
Cancer Res.
, vol.72
, pp. 1149-1156
-
-
Shigechi, T.1
Tomida, J.2
Sato, K.3
Kobayashi, M.4
Eykelenboom, J.K.5
Pessina, F.6
Zhang, Y.7
Uchida, E.8
Ishiai, M.9
Lowndes, N.F.10
-
49
-
-
84863753191
-
A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2
-
Schlacher, K., Wu, H. And Jasin, M. (2012) A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2. Cancer Cell, 22, 106-116.
-
(2012)
Cancer Cell
, vol.22
, pp. 106-116
-
-
Schlacher, K.1
Wu, H.2
Jasin, M.3
-
50
-
-
4043133287
-
ATR couples FANCD2 monoubiquitination to the DNA-damage response
-
Andreassen, P. R., D'Andrea, A. D. And Taniguchi, T. (2004) ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes Dev., 18, 1958-1963.
-
(2004)
Genes Dev.
, vol.18
, pp. 1958-1963
-
-
Andreassen, P.R.1
D'Andrea, A.D.2
Taniguchi, T.3
-
51
-
-
34248184445
-
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated
-
Kennedy, R. D., Chen, C. C., Stuckert, P., Archila, E. M., De la Vega, M. A., Moreau, L. A., Shimamura, A. And D'Andrea, A. D. (2007) Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J. Clin. Invest., 117, 1440-1449.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1440-1449
-
-
Kennedy, R.D.1
Chen, C.C.2
Stuckert, P.3
Archila, E.M.4
De La Vega, M.A.5
Moreau, L.A.6
Shimamura, A.7
D'Andrea, A.D.8
-
52
-
-
84880784164
-
Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity
-
Koundrioukoff, S., Carignon, S., Techer, H., Letessier, A., Brison, O. And Debatisse, M. (2013) Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity. PLoS Genet., 9, e1003643.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003643
-
-
Koundrioukoff, S.1
Carignon, S.2
Techer, H.3
Letessier, A.4
Brison, O.5
Debatisse, M.6
-
53
-
-
84887081781
-
Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry
-
Sirbu, B. M., McDonald, W. H., Dungrawala, H., Badu-Nkansah, A., Kavanaugh, G. M., Chen, Y., Tabb, D. L. And Cortez, D. (2013) Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry. J. Biol. Chem., 288, 31458-31467.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 31458-31467
-
-
Sirbu, B.M.1
McDonald, W.H.2
Dungrawala, H.3
Badu-Nkansah, A.4
Kavanaugh, G.M.5
Chen, Y.6
Tabb, D.L.7
Cortez, D.8
-
54
-
-
55549137026
-
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway
-
Ishiai, M., Kitao, H., Smogorzewska, A., Tomida, J., Kinomura, A., Uchida, E., Saberi, A., Kinoshita, E., Kinoshita-Kikuta, E., Koike, T. et al. (2008) FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Nat. Struct. Mol. Biol., 15, 1138-1146.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 1138-1146
-
-
Ishiai, M.1
Kitao, H.2
Smogorzewska, A.3
Tomida, J.4
Kinomura, A.5
Uchida, E.6
Saberi, A.7
Kinoshita, E.8
Kinoshita-Kikuta, E.9
Koike, T.10
-
55
-
-
34247257202
-
The structural determinants of checkpoint activation
-
MacDougall, C. A., Byun, T. S., Van, C., Yee, M. C. And Cimprich, K. A. (2007) The structural determinants of checkpoint activation. Genes Dev., 21, 898-903.
-
(2007)
Genes Dev.
, vol.21
, pp. 898-903
-
-
MacDougall, C.A.1
Byun, T.S.2
Van, C.3
Yee, M.C.4
Cimprich, K.A.5
-
56
-
-
80054121212
-
Differential roles for Chk1 and FANCD2 in ATR-mediated signalling for psoralen photoactivation-induced senescence
-
Hovest, M. G., Krieg, T. And Herrmann, G. (2011) Differential roles for Chk1 and FANCD2 in ATR-mediated signalling for psoralen photoactivation-induced senescence. Exp. Dermatol., 20, 883-889.
-
(2011)
Exp. Dermatol.
, vol.20
, pp. 883-889
-
-
Hovest, M.G.1
Krieg, T.2
Herrmann, G.3
-
57
-
-
67649842315
-
Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival
-
Wagner, J. M. And Karnitz, L. M. (2009) Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival. Mol. Pharmacol., 76, 208-214.
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 208-214
-
-
Wagner, J.M.1
Karnitz, L.M.2
-
58
-
-
84881539569
-
A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair
-
Tomida, J., Itaya, A., Shigechi, T., Unno, J., Uchida, E., Ikura, M., Masuda, Y., Matsuda, S., Adachi, J., Kobayashi, M. et al. (2013) A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair. Nucleic Acids Res., 41, 6930-6941.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 6930-6941
-
-
Tomida, J.1
Itaya, A.2
Shigechi, T.3
Unno, J.4
Uchida, E.5
Ikura, M.6
Masuda, Y.7
Matsuda, S.8
Adachi, J.9
Kobayashi, M.10
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