DNA damage-induced CHK1 autophosphorylation at Ser296 is regulated by an intramolecular mechanism

FEBS Letters

Volumn 586, Issue 22, 2012, Pages 3974-3979

  Okita, Naoyuki ^a   Minato, Shota ^a   Ohmi, Eri ^a   Tanuma, Sei Ichi ^a   Higami, Yoshikazu ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

ATR; CHK1; cis Autophosphorylation; DNA damage; Kinase

Indexed keywords

CHECKPOINT KINASE 1;

AMINO ACID COMPOSITION; ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA DAMAGE; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; SERINE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84868599554     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.09.048     Document Type: Article

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