-
1
-
-
0034749999
-
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity
-
Adolfsson J, Borge OJ, Bryder D, Theilgaard-Monch K, Astrand-Grundstrom I, Sitnicka E, Sasaki Y, Jacobsen SE (2001) Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity 15:659–669
-
(2001)
Immunity
, vol.15
, pp. 659-669
-
-
Adolfsson, J.1
Borge, O.J.2
Bryder, D.3
Theilgaard-Monch, K.4
Astrand-Mrundstrom, I.5
Sitnicka, E.6
Sasaki, Y.7
Jacobsen, S.E.8
-
2
-
-
20244387299
-
Identification of Flt3 + lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
-
Adolfsson J, Mansson R, Buza-Vidas N, Hultquist A, Liuba K, Jensen CT, Bryder D, Yang L, Borge OJ, Thoren LA, Anderson K, Sitnicka E, Sasaki Y, Sigvardsson M, Jacobsen SE (2005) Identification of Flt3 + lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 121:295–306
-
(2005)
Cell
, vol.121
, pp. 295-306
-
-
Adolfsson, J.1
Mansson, R.2
Buza-Midas, N.3
Hultquist, A.4
Liuba, K.5
Jensen, C.T.6
Bryder, D.7
Yang, L.8
Borge, O.J.9
Thoren, L.A.10
Anderson, K.11
Sitnicka, E.12
Sasaki, Y.13
Sigvardsson, M.14
Jacobsen, S.E.15
-
3
-
-
37049009268
-
Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47
-
Agata Y, Tamaki N, Sakamoto S, Ikawa T, Masuda K, Kawamoto H, Murre C (2007) Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47. Immunity 27:871–884
-
(2007)
Immunity
, vol.27
, pp. 871-884
-
-
Agata, Y.1
Tamaki, N.2
Sakamoto, S.3
Ikawa, T.4
Masuda, K.5
Kawamoto, H.6
Murre, C.7
-
4
-
-
0037320932
-
Thymopoiesis independent of common lymphoid progenitors
-
Allman D, Sambandam A, Kim S, Miller JP, Pagan A, Well D, Meraz A, Bhandoola A (2003) Thymopoiesis independent of common lymphoid progenitors. Nat Immunol 4:168–174
-
(2003)
Nat Immunol
, vol.4
, pp. 168-174
-
-
Allman, D.1
Sambandam, A.2
Kim, S.3
Miller, J.P.4
Pagan, A.5
Well, D.6
Meraz, A.7
Bhandoola, A.8
-
5
-
-
84878267796
-
Polycomb complexes in stem cells and embryonic development
-
Aloia L, di Stefano B, di Croce L (2013) Polycomb complexes in stem cells and embryonic development. Development 140:2525–2534
-
(2013)
Development
, vol.140
, pp. 2525-2534
-
-
Aloia, L.1
Di Stefano, B.2
Di Croce, L.3
-
6
-
-
14944341196
-
The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage, and natural killer cell but no B-lymphocyte potential
-
Balciunaite G, Ceredig R, Rolink AG (2005) The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage, and natural killer cell but no B-lymphocyte potential. Blood 105:1930–1936
-
(2005)
Blood
, vol.105
, pp. 1930-1936
-
-
Balciunaite, G.1
Ceredig, R.2
Rolink, A.G.3
-
7
-
-
42049087865
-
The earliest thymic progenitors for T cells possess myeloid lineage potential
-
Bell JJ, Bhandoola A (2008) The earliest thymic progenitors for T cells possess myeloid lineage potential. Nature 452:764–767
-
(2008)
Nature
, vol.452
, pp. 764-767
-
-
Bell, J.J.1
Bhandoola, A.2
-
8
-
-
70350654370
-
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
-
Broske AM, Vockentanz L, Kharazi S, Huska MR, Mancini E, Scheller M, Kuhl C, Enns A, Prinz M, Jaenisch R, Nerlov C, Leutz A, Andrade-Navarro MA, Jacobsen SE, Rosenbauer F (2009) DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat Genet 41:1207–1215
-
(2009)
Nat Genet
, vol.41
, pp. 1207-1215
-
-
Broske, A.M.1
Vockentanz, L.2
Kharazi, S.3
Huska, M.R.4
Mancini, E.5
Scheller, M.6
Kuhl, C.7
Enns, A.8
Prinz, M.9
Jaenisch, R.10
Nerlov, C.11
Leutz, A.12
Andrade-Mavarro, M.A.13
Jacobsen, S.E.14
Rosenbauer, F.15
-
9
-
-
2542442633
-
Transcriptional control of early B cell development
-
Busslinger M (2004) Transcriptional control of early B cell development. Annu Rev Immunol 22:55–79
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 55-79
-
-
Busslinger, M.1
-
10
-
-
38549106607
-
Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion
-
Cales C, Roman-Trufero M, Pavon L, Serrano I, Melgar T, Endoh M, Perez C, Koseki H, Vidal M (2008) Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion. Mol Cell Biol 28:1018–1028
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1018-1028
-
-
Cales, C.1
Roman-Mrufero, M.2
Pavon, L.3
Serrano, I.4
Melgar, T.5
Endoh, M.6
Perez, C.7
Koseki, H.8
Vidal, M.9
-
11
-
-
0035807964
-
Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells
-
Christensen JL, Weissman IL (2001) Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells. Proc Natl Acad Sci USA 98:14541–14546
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14541-14546
-
-
Christensen, J.L.1
Weissman, I.L.2
-
12
-
-
34848853915
-
Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors
-
Cobaleda C, Jochum W, Busslinger M (2007) Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors. Nature 449:473–477
-
(2007)
Nature
, vol.449
, pp. 473-477
-
-
Cobaleda, C.1
Jochum, W.2
Busslinger, M.3
-
14
-
-
0034717335
-
Regulation of B lymphocyte and macrophage development by graded expression of PU.1
-
Dekoter RP, Singh H (2000) Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288:1439–1441
-
(2000)
Science
, vol.288
, pp. 1439-1441
-
-
Dekoter, R.P.1
Singh, H.2
-
15
-
-
48749094942
-
E2A proteins promote development of lymphoid-primed multipotent progenitors
-
Dias S, Mansson R, Gurbuxani S, Sigvardsson M, Kee BL (2008) E2A proteins promote development of lymphoid-primed multipotent progenitors. Immunity 29:217–227
-
(2008)
Immunity
, vol.29
, pp. 217-227
-
-
Dias, S.1
Mansson, R.2
Gurbuxani, S.3
Sigvardsson, M.4
Kee, B.L.5
-
16
-
-
0037839780
-
Bcl11: Sibling rivalry in lymphoid development
-
Durum SK (2003) Bcl11: Sibling rivalry in lymphoid development. Nat Immunol 4:512–514
-
(2003)
Nat Immunol
, vol.4
, pp. 512-514
-
-
Durum, S.K.1
-
17
-
-
84881464799
-
Critical role of p38 and GATA3 in natural helper cell function
-
Furusawa J, Moro K, Motomura Y, Okamoto K, Zhu J, Takayanagi H, Kubo M, Koyasu S (2013) Critical role of p38 and GATA3 in natural helper cell function. J Immunol 191:1818–1826
-
(2013)
J Immunol
, vol.191
, pp. 1818-1826
-
-
Furusawa, J.1
Moro, K.2
Motomura, Y.3
Okamoto, K.4
Zhu, J.5
Takayanagi, H.6
Kubo, M.7
Koyasu, S.8
-
18
-
-
70349446453
-
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development
-
Gascoyne DM, Long E, Veiga-Fernandes H, de Boer J, Williams O, Seddon B, Coles M, Kioussis D, Brady HJ (2009) The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol 10:1118–1124
-
(2009)
Nat Immunol
, vol.10
, pp. 1118-1124
-
-
Gascoyne, D.M.1
Long, E.2
Veiga-Mernandes, H.3
De Boer, J.4
Williams, O.5
Seddon, B.6
Coles, M.7
Kioussis, D.8
Brady, H.J.9
-
19
-
-
0027153201
-
A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8—triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
-
Godfrey DI, Kennedy J, Suda T, Zlotnik A (1993) A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8—triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J Immunol 150:4244–4252
-
(1993)
J Immunol
, vol.150
, pp. 4244-4252
-
-
Godfrey, D.I.1
Kennedy, J.2
Suda, T.3
Zlotnik, A.4
-
20
-
-
84866519013
-
Retinoic-acidreceptor- related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation
-
Halim TY, Maclaren A, Romanish MT, Gold MJ, McNagny KM, Takei F (2012) Retinoic-acidreceptor- related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation. Immunity 37:463–474
-
(2012)
Immunity
, vol.37
, pp. 463-474
-
-
Halim, T.Y.1
Maclaren, A.2
Romanish, M.T.3
Gold, M.J.4
Mc Nagny, K.M.5
Takei, F.6
-
21
-
-
0025868702
-
Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
-
Hardy RR, Carmack CE, Shinton SA, Kemp JD, Hayakawa K (1991) Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J Exp Med 173:1213–1225
-
(1991)
J Exp Med
, vol.173
, pp. 1213-1225
-
-
Hardy, R.R.1
Carmack, C.E.2
Shinton, S.A.3
Kemp, J.D.4
Hayakawa, K.5
-
22
-
-
0029788072
-
Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus
-
Hattori N, Kawamoto H, Fujimoto S, Kuno K, Katsura Y (1996) Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus. J Exp Med 184:1137–1147
-
(1996)
J Exp Med
, vol.184
, pp. 1137-1147
-
-
Hattori, N.1
Kawamoto, H.2
Fujimoto, S.3
Kuno, K.4
Katsura, Y.5
-
23
-
-
84868340057
-
Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest
-
Hidalgo I, Herrera-Merchan A, Ligos JM, Carramolino L, Nunez J, Martinez F, Dominguez O, Torres M, Gonzalez S (2012) Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest. Cell Stem Cell 11:649–662
-
(2012)
Cell Stem Cell
, vol.11
, pp. 649-662
-
-
Hidalgo, I.1
Herrera-Merchan, A.2
Ligos, J.M.3
Carramolino, L.4
Nunez, J.5
Martinez, F.6
Dominguez, O.7
Torres, M.8
Gonzalez, S.9
-
24
-
-
73949143689
-
GATA-3 is required for early T lineage progenitor development
-
Hosoya T, Kuroha T, Moriguchi T, Cummings D, Maillard I, Lim KC, Engel JD (2009) GATA-3 is required for early T lineage progenitor development. J Exp Med 206:2987–3000
-
(2009)
J Exp Med
, vol.206
, pp. 2987-3000
-
-
Hosoya, T.1
Kuroha, T.2
Moriguchi, T.3
Cummings, D.4
Maillard, I.5
Lim, K.C.6
Engel, J.D.7
-
25
-
-
84867769688
-
The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells
-
Hoyler T, Klose CS, Souabni A, Turqueti-Neves A, Pfeifer D, Rawlins EL, Voehringer D, Busslinger M, Diefenbach A (2012) The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells. Immunity 37:634–648
-
(2012)
Immunity
, vol.37
, pp. 634-648
-
-
Hoyler, T.1
Klose, C.S.2
Souabni, A.3
Turqueti-Meves, A.4
Pfeifer, D.5
Rawlins, E.L.6
Voehringer, D.7
Busslinger, M.8
Diefenbach, A.9
-
26
-
-
0036669273
-
Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow
-
Igarashi H, Gregory SC, Yokota T, Sakaguchi N, Kincade PW (2002) Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity 17:117–130
-
(2002)
Immunity
, vol.17
, pp. 117-130
-
-
Igarashi, H.1
Gregory, S.C.2
Yokota, T.3
Sakaguchi, N.4
Kincade, P.W.5
-
27
-
-
0035942179
-
Commitment to natural killer cells requires the helix-loop-helix inhibitor Id2
-
Ikawa T, Fujimoto S, Kawamoto H, Katsura Y, Yokota Y (2001) Commitment to natural killer cells requires the helix-loop-helix inhibitor Id2. Proc Natl Acad Sci USA 98:5164–5169
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5164-5169
-
-
Ikawa, T.1
Fujimoto, S.2
Kawamoto, H.3
Katsura, Y.4
Yokota, Y.5
-
28
-
-
77954321988
-
An essential developmental checkpoint for production of the T cell lineage
-
Ikawa T, Hirose S, Masuda K, Kakugawa K, Satoh R, Shibano-Satoh A, Kominami R, Katsura Y, Kawamoto H (2010) An essential developmental checkpoint for production of the T cell lineage. Science 329:93–96
-
(2010)
Science
, vol.329
, pp. 93-96
-
-
Ikawa, T.1
Hirose, S.2
Masuda, K.3
Kakugawa, K.4
Satoh, R.5
Shibano-Matoh, A.6
Kominami, R.7
Katsura, Y.8
Kawamoto, H.9
-
29
-
-
0033454058
-
Commitment of common T/natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay
-
Ikawa T, Kawamoto H, Fujimoto S, Katsura Y (1999) Commitment of common T/natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay. J Exp Med 190:1617–1626
-
(1999)
J Exp Med
, vol.190
, pp. 1617-1626
-
-
Ikawa, T.1
Kawamoto, H.2
Fujimoto, S.3
Katsura, Y.4
-
31
-
-
1642311876
-
Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent
-
Ikawa T, Kawamoto H, Wright LY, Murre C (2004) Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent. Immunity 20:349–360
-
(2004)
Immunity
, vol.20
, pp. 349-360
-
-
Ikawa, T.1
Kawamoto, H.2
Wright, L.Y.3
Murre, C.4
-
32
-
-
0026500983
-
Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation
-
Ikuta K, Weissman IL (1992) Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. Proc Natl Acad Sci USA 89:1502–1506
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1502-1506
-
-
Ikuta, K.1
Weissman, I.L.2
-
33
-
-
70350093398
-
Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development
-
Inlay MA, Bhattacharya D, Sahoo D, Serwold T, Seita J, Karsunky H, Plevritis SK, Dill DL, Weissman IL (2009) Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev 23:2376–2381
-
(2009)
Genes Dev
, vol.23
, pp. 2376-2381
-
-
Inlay, M.A.1
Bhattacharya, D.2
Sahoo, D.3
Serwold, T.4
Seita, J.5
Karsunky, H.6
Plevritis, S.K.7
Dill, D.L.8
Weissman, I.L.9
-
34
-
-
33344469959
-
The polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
-
Kamminga LM, Bystrykh LV, de Boer A, Houwer S, Douma J, Weersing E, Dontje B, de Haan G (2006) The polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood 107:2170–2179
-
(2006)
Blood
, vol.107
, pp. 2170-2179
-
-
Kamminga, L.M.1
Bystrykh, L.V.2
De Boer, A.3
Houwer, S.4
Douma, J.5
Weersing, E.6
Dontje, B.7
De Haan, G.8
-
35
-
-
77958532465
-
A map for lineage restriction of progenitors during hematopoiesis: The essence of the myeloid-based model
-
Kawamoto H, Ikawa T, Masuda K, Wada H, Katsura Y (2010) A map for lineage restriction of progenitors during hematopoiesis: The essence of the myeloid-based model. Immunol Rev 238:23–36
-
(2010)
Immunol Rev
, vol.238
, pp. 23-36
-
-
Kawamoto, H.1
Ikawa, T.2
Masuda, K.3
Wada, H.4
Katsura, Y.5
-
36
-
-
0034610970
-
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15- deficient mice
-
Kennedy MK, Glaccum M, Brown SN, Butz EA, Viney JL, Embers M, Matsuki N, Charrier K, Sedger L, Willis CR, Brasel K, Morrissey PJ, Stocking K, Schuh JC, Joyce S, Peschon JJ (2000) Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15- deficient mice. J Exp Med 191:771–780
-
(2000)
J Exp Med
, vol.191
, pp. 771-780
-
-
Kennedy, M.K.1
Glaccum, M.2
Brown, S.N.3
Butz, E.A.4
Viney, J.L.5
Embers, M.6
Matsuki, N.7
Charrier, K.8
Sedger, L.9
Willis, C.R.10
Brasel, K.11
Morrissey, P.J.12
Stocking, K.13
Schuh, J.C.14
Joyce, S.15
Peschon, J.J.16
-
37
-
-
18244386710
-
IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF
-
Kikuchi K, Lai AY, Hsu CL, Kondo M (2005) IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF. J Exp Med 201:1197–1203
-
(2005)
J Exp Med
, vol.201
, pp. 1197-1203
-
-
Kikuchi, K.1
Lai, A.Y.2
Hsu, C.L.3
Kondo, M.4
-
38
-
-
84876485242
-
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation
-
Klauke K, Radulovic V, Broekhuis M, Weersing E, Zwart E, Olthof S, Ritsema M, Bruggeman S, Wu X, Helin K, Bystrykh L, de Haan G (2013) Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation. Nat Cell Biol 15:353–362
-
(2013)
Nat Cell Biol
, vol.15
, pp. 353-362
-
-
Klauke, K.1
Radulovic, V.2
Broekhuis, M.3
Weersing, E.4
Zwart, E.5
Olthof, S.6
Ritsema, M.7
Bruggeman, S.8
Wu, X.9
Helin, K.10
Bystrykh, L.11
De Haan, G.12
-
39
-
-
84862703793
-
Transcriptional control of innate lymphocyte fate decisions
-
Klose CS, Hoyler T, Kiss EA, Tanriver Y, Diefenbach A (2012) Transcriptional control of innate lymphocyte fate decisions. Curr Opin Immunol 24:290–296
-
(2012)
Curr Opin Immunol
, vol.24
, pp. 290-296
-
-
Klose, C.S.1
Hoyler, T.2
Kiss, E.A.3
Tanriver, Y.4
Diefenbach, A.5
-
40
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo M, Weissman IL, Akashi K (1997) Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91:661–672
-
(1997)
Cell
, vol.91
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
41
-
-
84881236410
-
Positive feedback between PU.1 and the cell cycle controls myeloid differentiation
-
Kueh HY, Champhekhar A, Nutt SL, Elowitz MB, Rothenberg EV (2013) Positive feedback between PU.1 and the cell cycle controls myeloid differentiation. Science 341:670–673
-
(2013)
Science
, vol.341
, pp. 670-673
-
-
Kueh, H.Y.1
Champhekhar, A.2
Nutt, S.L.3
Elowitz, M.B.4
Rothenberg, E.V.5
-
42
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
Lee PP, Fitzpatrick DR, Beard C, Jessup HK, Lehar S, Makar KW, Perez-Melgosa M, Sweetser MT, Schlissel MS, Nguyen S, Cherry SR, Tsai JH, Tucker SM, Weaver WM, Kelso A, Jaenisch R, Wilson CB (2001) A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 15:763–774
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
Fitzpatrick, D.R.2
Beard, C.3
Jessup, H.K.4
Lehar, S.5
Makar, K.W.6
Perez-Melgosa, M.7
Sweetser, M.T.8
Schlissel, M.S.9
Nguyen, S.10
Cherry, S.R.11
Tsai, J.H.12
Tucker, S.M.13
Weaver, W.M.14
Kelso, A.15
Jaenisch, R.16
Wilson, C.B.17
-
43
-
-
84873595786
-
LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance
-
Lee SU, Maeda M, Ishikawa Y, Li SM, Wilson A, Jubb AM, Sakurai N, Weng L, Fiorini E, Radtke F, Yan M, Macdonald HR, Chen CC, Maeda T (2013) LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance. Blood 121:918–929
-
(2013)
Blood
, vol.121
, pp. 918-929
-
-
Lee, S.U.1
Maeda, M.2
Ishikawa, Y.3
Li, S.M.4
Wilson, A.5
Jubb, A.M.6
Sakurai, N.7
Weng, L.8
Fiorini, E.9
Radtke, F.10
Yan, M.11
Macdonald, H.R.12
Chen, C.C.13
Maeda, T.14
-
44
-
-
77954329976
-
An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b
-
Li L, Leid M, Rothenberg EV (2010a) An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b. Science 329:89–93
-
(2010)
Science
, vol.329
, pp. 89-93
-
-
Li, L.1
Leid, M.2
Rothenberg, E.V.3
-
45
-
-
77954326626
-
Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion
-
Li P, Burke S, Wang J, Chen X, Ortiz M, Lee SC, Lu D, Campos L, Goulding D, Ng BL, Dougan G, Huntly B, Gottgens B, Jenkins NA, Copeland NG, Colucci F, Liu P (2010b) Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion. Science 329:85–89
-
(2010)
Science
, vol.329
, pp. 85-89
-
-
Li, P.1
Burke, S.2
Wang, J.3
Chen, X.4
Ortiz, M.5
Lee, S.C.6
Lu, D.7
Campos, L.8
Goulding, D.9
Ng, B.L.10
Dougan, G.11
Huntly, B.12
Gottgens, B.13
Jenkins, N.A.14
Copeland, N.G.15
Colucci, F.16
Liu, P.17
-
46
-
-
0030483542
-
Identification of the earliest B lineage stage in mouse bone marrow
-
Li YS, Wasserman R, Hayakawa K, Hardy RR (1996) Identification of the earliest B lineage stage in mouse bone marrow. Immunity 5:527–535
-
(1996)
Immunity
, vol.5
, pp. 527-535
-
-
Li, Y.S.1
Wasserman, R.2
Hayakawa, K.3
Hardy, R.R.4
-
47
-
-
84873129944
-
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function
-
Liu B, Liu YF, Du YR, Mardaryev AN, Yang W, Chen H, Xu ZM, Xu CQ, Zhang XR, Botchkarev VA, Zhang Y, Xu GL (2013) Cbx4 regulates the proliferation of thymic epithelial cells and thymus function. Development 140:780–788
-
(2013)
Development
, vol.140
, pp. 780-788
-
-
Liu, B.1
Liu, Y.F.2
Du, Y.R.3
Mardaryev, A.N.4
Yang, W.5
Chen, H.6
Xu, Z.M.7
Xu, C.Q.8
Zhang, X.R.9
Botchkarev, V.A.10
Zhang, Y.11
Xu, G.L.12
-
48
-
-
0038516237
-
Bcl11a is essential for normal lymphoid development
-
Liu P, Keller JR, Ortiz M, Tessarollo L, Rachel RA, Nakamura T, Jenkins NA, Copeland NG (2003) Bcl11a is essential for normal lymphoid development. Nat Immunol 4:525–532
-
(2003)
Nat Immunol
, vol.4
, pp. 525-532
-
-
Liu, P.1
Keller, J.R.2
Ortiz, M.3
Tessarollo, L.4
Rachel, R.A.5
Nakamura, T.6
Jenkins, N.A.7
Copeland, N.G.8
-
49
-
-
27144501454
-
The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors
-
Lu M, Tayu R, Ikawa T, Masuda K, Matsumoto I, Mugishima H, Kawamoto H, Katsura Y (2005) The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors. J Immunol 175:5848–5856
-
(2005)
J Immunol
, vol.175
, pp. 5848-5856
-
-
Lu, M.1
Tayu, R.2
Ikawa, T.3
Masuda, K.4
Matsumoto, I.5
Mugishima, H.6
Kawamoto, H.7
Katsura, Y.8
-
50
-
-
84879423061
-
Role of LRF/pokemon in lineage fate decisions
-
Lunardi A, Guarnerio J, Wang G, Maeda T, Pandolfi PP (2013) Role of LRF/pokemon in lineage fate decisions. Blood 121:2845–2853
-
(2013)
Blood
, vol.121
, pp. 2845-2853
-
-
Lunardi, A.1
Guarnerio, J.2
Wang, G.3
Maeda, T.4
Pandolfi, P.P.5
-
51
-
-
34248580502
-
Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF
-
Maeda T, Merghoub T, Hobbs RM, Dong L, Maeda M, Zakrzewski J, Van den Brink MR, Zelent A, Shigematsu H, Akashi K, Teruya-Feldstein J, Cattoretti G, Pandolfi PP (2007) Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF. Science 316:860–866
-
(2007)
Science
, vol.316
, pp. 860-866
-
-
Maeda, T.1
Merghoub, T.2
Hobbs, R.M.3
Dong, L.4
Maeda, M.5
Zakrzewski, J.6
Van Den Brink, M.R.7
Zelent, A.8
Shigematsu, H.9
Akashi, K.10
Teruya-Meldstein, J.11
Cattoretti, G.12
Pandolfi, P.P.13
-
52
-
-
0346752253
-
Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells
-
Makar KW, Perez-Melgosa M, Shnyreva M, Weaver WM, Fitzpatrick DR, Wilson CB (2003) Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells. Nat Immunol 4:1183–1190
-
(2003)
Nat Immunol
, vol.4
, pp. 1183-1190
-
-
Makar, K.W.1
Perez-Melgosa, M.2
Shnyreva, M.3
Weaver, W.M.4
Fitzpatrick, D.R.5
Wilson, C.B.6
-
53
-
-
77951259076
-
Transcription control of early B cell differentiation
-
Mandel EM, Grosschedl R (2010) Transcription control of early B cell differentiation. Curr Opin Immunol 22:161–167
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 161-167
-
-
Mandel, E.M.1
Grosschedl, R.2
-
54
-
-
77951002652
-
Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity
-
Mansson R, Zandi S, Welinder E, Tsapogas P, Sakaguchi N, Bryder D, Sigvardsson M (2010) Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity. Blood 115:2601–2609
-
(2010)
Blood
, vol.115
, pp. 2601-2609
-
-
Mansson, R.1
Zandi, S.2
Welinder, E.3
Tsapogas, P.4
Sakaguchi, N.5
Bryder, D.6
Sigvardsson, M.7
-
55
-
-
0033980393
-
Helix-loop-helix proteins: Regulators of transcription in eukaryotic organisms
-
Massari ME, Murre C (2000) Helix-loop-helix proteins: regulators of transcription in eukaryotic organisms. Mol Cell Biol 20:429–440
-
(2000)
Mol Cell Biol
, vol.20
, pp. 429-440
-
-
Massari, M.E.1
Murre, C.2
-
56
-
-
35748931463
-
T cell lineage determination precedes the initiation of TCR beta gene rearrangement
-
Masuda K, Kakugawa K, Nakayama T, Minato N, Katsura Y, Kawamoto H (2007) T cell lineage determination precedes the initiation of TCR beta gene rearrangement. J Immunol 179:3699–3706
-
(2007)
J Immunol
, vol.179
, pp. 3699-3706
-
-
Masuda, K.1
Kakugawa, K.2
Nakayama, T.3
Minato, N.4
Katsura, Y.5
Kawamoto, H.6
-
57
-
-
0027305022
-
Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation
-
Matsuzaki Y, Gyotoku J, Ogawa M, Nishikawa S, Katsura Y, Gachelin G, Nakauchi H (1993) Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation. J Exp Med 178:1283–1292
-
(1993)
J Exp Med
, vol.178
, pp. 1283-1292
-
-
Matsuzaki, Y.1
Gyotoku, J.2
Ogawa, M.3
Nishikawa, S.4
Katsura, Y.5
Gachelin, G.6
Nakauchi, H.7
-
58
-
-
5044249424
-
Assembling a gene regulatory network for specification of the B cell fate
-
Medina KL, Pongubala JM, Reddy KL, Lancki DW, Dekoter R, Kieslinger M, Grosschedl R, Singh H (2004) Assembling a gene regulatory network for specification of the B cell fate. Dev Cell 7:607–617
-
(2004)
Dev Cell
, vol.7
, pp. 607-617
-
-
Medina, K.L.1
Pongubala, J.M.2
Reddy, K.L.3
Lancki, D.W.4
Dekoter, R.5
Kieslinger, M.6
Grosschedl, R.7
Singh, H.8
-
59
-
-
38949101970
-
Thymocyte proliferation induced by pre- T cell receptor signaling is maintained through polycomb gene product Bmi-1-mediated Cdkn2a repression
-
Miyazaki M, Miyazaki K, Itoi M, Katoh Y, Guo Y, Kanno R, Katoh-Fukui Y, Honda H, Amagai T, van Lohuizen M, Kawamoto H, Kanno M (2008) Thymocyte proliferation induced by pre- T cell receptor signaling is maintained through polycomb gene product Bmi-1-mediated Cdkn2a repression. Immunity 28:231–245
-
(2008)
Immunity
, vol.28
, pp. 231-245
-
-
Miyazaki, M.1
Miyazaki, K.2
Itoi, M.3
Katoh, Y.4
Guo, Y.5
Kanno, R.6
Katoh-Mukui, Y.7
Honda, H.8
Amagai, T.9
Van Lohuizen, M.10
Kawamoto, H.11
Kanno, M.12
-
60
-
-
84867773093
-
The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells
-
Mjosberg J, Bernink J, Golebski K, Karrich JJ, Peters CP, Blom B, te Velde AA, Fokkens WJ, van Drunen CM, Spits H (2012) The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells. Immunity 37:649–659
-
(2012)
Immunity
, vol.37
, pp. 649-659
-
-
Mjosberg, J.1
Bernink, J.2
Golebski, K.3
Karrich, J.J.4
Peters, C.P.5
Blom, B.6
Te Velde, A.A.7
Fokkens, W.J.8
Van Drunen, C.M.9
Spits, H.10
-
61
-
-
84055218931
-
Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells
-
Mochizuki-Kashio M, Mishima Y, Miyagi S, Negishi M, Saraya A, Konuma T, Shinga J, Koseki H, Iwama A (2011) Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells. Blood 118:6553–6561
-
(2011)
Blood
, vol.118
, pp. 6553-6561
-
-
Mochizuki-Mashio, M.1
Mishima, Y.2
Miyagi, S.3
Negishi, M.4
Saraya, A.5
Konuma, T.6
Shinga, J.7
Koseki, H.8
Iwama, A.9
-
62
-
-
75749122181
-
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
-
Moro K, Yamada T, Tanabe M, Takeuchi T, Ikawa T, Kawamoto H, Furusawa J, Ohtani M, Fujii H, Koyasu S (2010) Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Nature 463:540–544
-
(2010)
Nature
, vol.463
, pp. 540-544
-
-
Moro, K.1
Yamada, T.2
Tanabe, M.3
Takeuchi, T.4
Ikawa, T.5
Kawamoto, H.6
Furusawa, J.7
Ohtani, M.8
Fujii, H.9
Koyasu, S.10
-
63
-
-
84880780575
-
Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells
-
Nechanitzky R, Akbas D, Scherer S, Gyory I, Hoyler T, Ramamoorthy S, Diefenbach A, Grosschedl R (2013) Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells. Nat Immunol 14:867–875
-
(2013)
Nat Immunol
, vol.14
, pp. 867-875
-
-
Nechanitzky, R.1
Akbas, D.2
Scherer, S.3
Gyory, I.4
Hoyler, T.5
Ramamoorthy, S.6
Diefenbach, A.7
Grosschedl, R.8
-
64
-
-
77951817855
-
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
-
Neill DR, Wong SH, Bellosi A, Flynn RJ, Daly M, Langford TK, Bucks C, Kane CM, Fallon PG, Pannell R, Jolin HE, Mc Kenzie AN (2010) Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 464:1367–1370
-
(2010)
Nature
, vol.464
, pp. 1367-1370
-
-
Neill, D.R.1
Wong, S.H.2
Bellosi, A.3
Flynn, R.J.4
Daly, M.5
Langford, T.K.6
Bucks, C.7
Kane, C.M.8
Fallon, P.G.9
Pannell, R.10
Jolin, H.E.11
Mc Kenzie, A.N.12
-
65
-
-
0033533891
-
Commitment to the B-lymphoid lineage depends on the transcription factor Pax5
-
Nutt SL, Heavey B, Rolink AG, Busslinger M (1999) Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 401:556–562
-
(1999)
Nature
, vol.401
, pp. 556-562
-
-
Nutt, S.L.1
Heavey, B.2
Rolink, A.G.3
Busslinger, M.4
-
66
-
-
34250212629
-
The transcriptional regulation of B cell lineage commitment
-
Nutt SL, Kee BL (2007) The transcriptional regulation of B cell lineage commitment. Immunity 26:715–725
-
(2007)
Immunity
, vol.26
, pp. 715-725
-
-
Nutt, S.L.1
Kee, B.L.2
-
67
-
-
77449159608
-
Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1
-
Oguro H, Yuan J, Ichikawa H, Ikawa T, Yamazaki S, Kawamoto H, Nakauchi H, Iwama A (2010) Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1. Cell Stem Cell 6:279–286
-
(2010)
Cell Stem Cell
, vol.6
, pp. 279-286
-
-
Oguro, H.1
Yuan, J.2
Ichikawa, H.3
Ikawa, T.4
Yamazaki, S.5
Kawamoto, H.6
Nakauchi, H.7
Iwama, A.8
-
68
-
-
84882351849
-
MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors
-
Okuyama K, Ikawa T, Gentner B, Hozumi K, Harnprasopwat R, Lu J, Yamashita R, Ha D, Toyoshima T, Chanda B, Kawamata T, Yokoyama K, Wang S, Ando K, Lodish HF, Tojo A, Kawamoto H, Kotani A (2013) MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors. Proc Natl Acad Sci USA 110:13410–13415
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 13410-13415
-
-
Okuyama, K.1
Ikawa, T.2
Gentner, B.3
Hozumi, K.4
Harnprasopwat, R.5
Lu, J.6
Yamashita, R.7
Ha, D.8
Toyoshima, T.9
Chanda, B.10
Kawamata, T.11
Yokoyama, K.12
Wang, S.13
Ando, K.14
Lodish, H.F.15
Tojo, A.16
Kawamoto, H.17
Kotani, A.18
-
69
-
-
0029796633
-
Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
-
Osawa M, Hanada K, Hamada H, Nakauchi H (1996) Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273:242–245
-
(1996)
Science
, vol.273
, pp. 242-245
-
-
Osawa, M.1
Hanada, K.2
Hamada, H.3
Nakauchi, H.4
-
70
-
-
0348110327
-
Critical roles for transcription factor GATA-3 in thymocyte development
-
Pai SY, Truitt ML, Ting CN, Leiden JM, Glimcher LH, Ho IC (2003) Critical roles for transcription factor GATA-3 in thymocyte development. Immunity 19:863–875
-
(2003)
Immunity
, vol.19
, pp. 863-875
-
-
Pai, S.Y.1
Truitt, M.L.2
Ting, C.N.3
Leiden, J.M.4
Glimcher, L.H.5
Ho, I.C.6
-
71
-
-
0038349957
-
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
-
Park IK, Qian D, Kiel M, Becker MW, Pihalja M, Weissman IL, Morrison SJ, Clarke MF (2003) Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423:302–305
-
(2003)
Nature
, vol.423
, pp. 302-305
-
-
Park, I.K.1
Qian, D.2
Kiel, M.3
Becker, M.W.4
Pihalja, M.5
Weissman, I.L.6
Morrison, S.J.7
Clarke, M.F.8
-
72
-
-
38449102306
-
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
-
Pongubala JM, Northrup DL, Lancki DW, Medina KL, Treiber T, Bertolino E, Thomas M, Grosschedl R, Allman D, Singh H (2008) Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat Immunol 9:203–215
-
(2008)
Nat Immunol
, vol.9
, pp. 203-215
-
-
Pongubala, J.M.1
Northrup, D.L.2
Lancki, D.W.3
Medina, K.L.4
Treiber, T.5
Bertolino, E.6
Thomas, M.7
Grosschedl, R.8
Allman, D.9
Singh, H.10
-
73
-
-
2942516896
-
Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages
-
Porritt HE, Rumfelt LL, Tabrizifard S, Schmitt TM, Zuniga-Pflucker JC, Petrie HT (2004) Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 20:735–745
-
(2004)
Immunity
, vol.20
, pp. 735-745
-
-
Porritt, H.E.1
Rumfelt, L.L.2
Tabrizifard, S.3
Schmitt, T.M.4
Zuniga-Mflucker, J.C.5
Petrie, H.T.6
-
74
-
-
77954926597
-
Systemically dispersed innate IL-13-expressing cells in type 2 immunity
-
Price AE, Liang HE, Sullivan BM, Reinhardt RL, Eisley CJ, Erle DJ, Locksley RM (2010) Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc Natl Acad Sci USA 107:11489–11494
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 11489-11494
-
-
Price, A.E.1
Liang, H.E.2
Sullivan, B.M.3
Reinhardt, R.L.4
Eisley, C.J.5
Erle, D.J.6
Locksley, R.M.7
-
75
-
-
84864147148
-
The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis
-
Revilla IDR, Bilic I, Vilagos B, Tagoh H, Ebert A, Tamir IM, Smeenk L, Trupke J, Sommer A, Jaritz M, Busslinger M (2012) The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis. EMBO J 31:3130–3146
-
(2012)
EMBO J
, vol.31
, pp. 3130-3146
-
-
Revilla, I.D.R.1
Bilic, I.2
Vilagos, B.3
Tagoh, H.4
Ebert, A.5
Tamir, I.M.6
Smeenk, L.7
Trupke, J.8
Sommer, A.9
Jaritz, M.10
Busslinger, M.11
-
76
-
-
47849118209
-
Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros
-
Reynaud D, Demarco IA, Reddy KL, Schjerven H, Bertolino E, Chen Z, Smale ST, Winandy S, Singh H (2008) Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol 9:927–936
-
(2008)
Nat Immunol
, vol.9
, pp. 927-936
-
-
Reynaud, D.1
Demarco, I.A.2
Reddy, K.L.3
Schjerven, H.4
Bertolino, E.5
Chen, Z.6
Smale, S.T.7
Winandy, S.8
Singh, H.9
-
77
-
-
0034970328
-
Identification of committed NK cell progenitors in adult murine bone marrow
-
Rosmaraki EE, Douagi I, Roth C, Colucci F, Cumano A, di Santo JP (2001) Identification of committed NK cell progenitors in adult murine bone marrow. Eur J Immunol 31:1900–1909
-
(2001)
Eur J Immunol
, vol.31
, pp. 1900-1909
-
-
Rosmaraki, E.E.1
Douagi, I.2
Roth, C.3
Colucci, F.4
Cumano, A.5
Di Santo, J.P.6
-
78
-
-
84859161260
-
Transcriptional drivers of the T-cell lineage program
-
Rothenberg EV (2012) Transcriptional drivers of the T-cell lineage program. Curr Opin Immunol 24:132–138
-
(2012)
Curr Opin Immunol
, vol.24
, pp. 132-138
-
-
Rothenberg, E.V.1
-
80
-
-
84879588905
-
The Satb1 protein directs hematopoietic stem cell differentiation toward lymphoid lineages
-
Satoh Y, Yokota T, Sudo T, Kondo M, Lai A, Kincade PW, Kouro T, Iida R, Kokame K, Miyata T, Habuchi Y, Matsui K, Tanaka H, Matsumura I, Oritani K, Kohwi-Shigematsu T, Kanakura Y (2013) The Satb1 protein directs hematopoietic stem cell differentiation toward lymphoid lineages. Immunity 38:1105–1115
-
(2013)
Immunity
, vol.38
, pp. 1105-1115
-
-
Satoh, Y.1
Yokota, T.2
Sudo, T.3
Kondo, M.4
Lai, A.5
Kincade, P.W.6
Kouro, T.7
Iida, R.8
Kokame, K.9
Miyata, T.10
Habuchi, Y.11
Matsui, K.12
Tanaka, H.13
Matsumura, I.14
Oritani, K.15
Kohwi-Mhigematsu, T.16
Kanakura, Y.17
-
81
-
-
34547126466
-
Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function
-
Schebesta A, McManus S, Salvagiotto G, Delogu A, Busslinger GA, Busslinger M (2007) Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function. Immunity 27:49–63
-
(2007)
Immunity
, vol.27
, pp. 49-63
-
-
Schebesta, A.1
Mc Manus, S.2
Salvagiotto, G.3
Delogu, A.4
Busslinger, G.A.5
Busslinger, M.6
-
82
-
-
0032532301
-
Critical involvement of Tcf-1 in expansion of thymocytes
-
Schilham MW, Wilson A, Moerer P, Benaissa-Trouw BJ, Cumano A, Clevers HC (1998) Critical involvement of Tcf-1 in expansion of thymocytes. J Immunol 161:3984–3991
-
(1998)
J Immunol
, vol.161
, pp. 3984-3991
-
-
Schilham, M.W.1
Wilson, A.2
Moerer, P.3
Benaissa-Mrouw, B.J.4
Cumano, A.5
Clevers, H.C.6
-
83
-
-
77949956058
-
Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus
-
Schlenner SM, Madan V, Busch K, Tietz A, Laufle C, Costa C, Blum C, Fehling HJ, Rodewald HR (2010) Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus. Immunity 32:426–436
-
(2010)
Immunity
, vol.32
, pp. 426-436
-
-
Schlenner, S.M.1
Madan, V.2
Busch, K.3
Tietz, A.4
Laufle, C.5
Costa, C.6
Blum, C.7
Fehling, H.J.8
Rodewald, H.R.9
-
84
-
-
33846902089
-
Selective thymus settling regulated by cytokine and chemokine receptors
-
Schwarz BA, Sambandam A, Maillard I, Harman BC, Love PE, Bhandoola A (2007) Selective thymus settling regulated by cytokine and chemokine receptors. J Immunol 178:2008–2017
-
(2007)
J Immunol
, vol.178
, pp. 2008-2017
-
-
Schwarz, B.A.1
Sambandam, A.2
Maillard, I.3
Harman, B.C.4
Love, P.E.5
Bhandoola, A.6
-
85
-
-
3042693975
-
Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A
-
Seet CS, Brumbaugh RL, Kee BL (2004) Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A. J Exp Med 199:1689–1700
-
(2004)
J Exp Med
, vol.199
, pp. 1689-1700
-
-
Seet, C.S.1
Brumbaugh, R.L.2
Kee, B.L.3
-
86
-
-
60549106831
-
E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors
-
Semerad CL, Mercer EM, Inlay MA, Weissman IL, Murre C (2009) E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors. Proc Natl Acad Sci USA 106:1930–1935
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1930-1935
-
-
Semerad, C.L.1
Mercer, E.M.2
Inlay, M.A.3
Weissman, I.L.4
Murre, C.5
-
87
-
-
0023922373
-
Purification and characterization of mouse hematopoietic stem cells
-
Spangrude GJ, Heimfeld S, Weissman IL (1988) Purification and characterization of mouse hematopoietic stem cells. Science 241:58–62
-
(1988)
Science
, vol.241
, pp. 58-62
-
-
Spangrude, G.J.1
Heimfeld, S.2
Weissman, I.L.3
-
88
-
-
84859384082
-
Innate lymphoid cells: Emerging insights in development, lineage relationships, and function
-
Spits H, Cupedo T (2012) Innate lymphoid cells: emerging insights in development, lineage relationships, and function. Annu Rev Immunol 30:647–675
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 647-675
-
-
Spits, H.1
Cupedo, T.2
-
89
-
-
48749101937
-
WNT signalling in the immune system: WNT is spreading its wings
-
Staal FJ, Luis TC, Tiemessen MM (2008) WNT signalling in the immune system: WNT is spreading its wings. Nat Rev Immunol 8:581–593
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 581-593
-
-
Staal, F.J.1
Luis, T.C.2
Tiemessen, M.M.3
-
90
-
-
50549083083
-
The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis
-
Staal FJ, Sen JM (2008) The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis. Eur J Immunol 38:1788–1794
-
(2008)
Eur J Immunol
, vol.38
, pp. 1788-1794
-
-
Staal, F.J.1
Sen, J.M.2
-
91
-
-
0037320925
-
Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement
-
Su IH, Basavaraj A, Krutchinsky AN, Hobert O, Ullrich A, Chait BT, Tarakhovsky A (2003) Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. Nat Immunol 4:124–131
-
(2003)
Nat Immunol
, vol.4
, pp. 124-131
-
-
Su, I.H.1
Basavaraj, A.2
Krutchinsky, A.N.3
Hobert, O.4
Ullrich, A.5
Chait, B.T.6
Tarakhovsky, A.7
-
92
-
-
0031051547
-
Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain
-
Suzuki H, Duncan GS, Takimoto H, Mak TW (1997) Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain. J Exp Med 185:499–505
-
(1997)
J Exp Med
, vol.185
, pp. 499-505
-
-
Suzuki, H.1
Duncan, G.S.2
Takimoto, H.3
Mak, T.W.4
-
93
-
-
34247337999
-
De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells
-
Tadokoro Y, Ema H, Okano M, Li E, Nakauchi H (2007) De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells. J Exp Med 204:715–722
-
(2007)
J Exp Med
, vol.204
, pp. 715-722
-
-
Tadokoro, Y.1
Ema, H.2
Okano, M.3
Li, E.4
Nakauchi, H.5
-
94
-
-
34250217913
-
Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3
-
Taghon T, Yui MA, Rothenberg EV (2007) Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3. Nat Immunol 8:845–855
-
(2007)
Nat Immunol
, vol.8
, pp. 845-855
-
-
Taghon, T.1
Yui, M.A.2
Rothenberg, E.V.3
-
95
-
-
0029828994
-
Transcription factor GATA-3 is required for development of the T-cell lineage
-
Ting CN, Olson MC, Barton KP, Leiden JM (1996) Transcription factor GATA-3 is required for development of the T-cell lineage. Nature 384:474–478
-
(1996)
Nature
, vol.384
, pp. 474-478
-
-
Ting, C.N.1
Olson, M.C.2
Barton, K.P.3
Leiden, J.M.4
-
96
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
Trowbridge JJ, Snow JW, Kim J, Orkin SH (2009) DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 5:442–449
-
(2009)
Cell Stem Cell
, vol.5
, pp. 442-449
-
-
Trowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
97
-
-
77956175900
-
New insights into the development of lymphoid tissues
-
van de Pavert SA, Mebius RE (2010) New insights into the development of lymphoid tissues. Nat Rev Immunol 10:664–674
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 664-674
-
-
Van De Pavert, S.A.1
Mebius, R.E.2
-
98
-
-
84875462758
-
Nonredundant and locusspecific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells
-
van den Boom V, Rozenveld-Geugien M, Bonardi F, Malanga D, van Gosliga D, Heijink AM, Viglietto G, Morrone G, Fusetti F, Vellenga E, Schuringa JJ (2013) Nonredundant and locusspecific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells. Blood 121:2452–2461
-
(2013)
Blood
, vol.121
, pp. 2452-2461
-
-
Van Den Boom, V.1
Rozenveld-Meugien, M.2
Bonardi, F.3
Malanga, D.4
Van Gosliga, D.5
Heijink, A.M.6
Viglietto, G.7
Morrone, G.8
Fusetti, F.9
Vellenga, E.10
Schuringa, J.J.11
-
99
-
-
0028985161
-
An HMG-box-containing T-cell factor required for thymocyte differentiation
-
Verbeek S, Izon D, Hofhuis F, Robanus-Maandag E, te Riele H, van de Wetering M, Oosterwegel M, Wilson A, Macdonald HR, Clevers H (1995) An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature 374:70–74
-
(1995)
Nature
, vol.374
, pp. 70-74
-
-
Verbeek, S.1
Izon, D.2
Hofhuis, F.3
Robanus-Maandag, E.4
Te Riele, H.5
Van De Wetering, M.6
Oosterwegel, M.7
Wilson, A.8
Macdonald, H.R.9
Clevers, H.10
-
100
-
-
42049089318
-
Adult T-cell progenitors retain myeloid potential
-
Wada H, Masuda K, Satoh R, Kakugawa K, Ikawa T, Katsura Y, Kawamoto H (2008) Adult T-cell progenitors retain myeloid potential. Nature 452:768–772
-
(2008)
Nature
, vol.452
, pp. 768-772
-
-
Wada, H.1
Masuda, K.2
Satoh, R.3
Kakugawa, K.4
Ikawa, T.5
Katsura, Y.6
Kawamoto, H.7
-
102
-
-
79961140554
-
A critical role for TCF-1 in T-lineage specification and differentiation
-
Weber BN, Chi AW, Chavez A, Yashiro-Ohtani Y, Yang Q, Shestova O, Bhandoola A (2011) A critical role for TCF-1 in T-lineage specification and differentiation. Nature 476:63–68
-
(2011)
Nature
, vol.476
, pp. 63-68
-
-
Weber, B.N.1
Chi, A.W.2
Chavez, A.3
Yashiro-Mhtani, Y.4
Yang, Q.5
Shestova, O.6
Bhandoola, A.7
-
103
-
-
80054805278
-
The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor
-
Welinder E, Mansson R, Mercer EM, Bryder D, Sigvardsson M, Murre C (2011) The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor. Proc Natl Acad Sci USA 108:17402–17407
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 17402-17407
-
-
Welinder, E.1
Mansson, R.2
Mercer, E.M.3
Bryder, D.4
Sigvardsson, M.5
Murre, C.6
-
104
-
-
84863393407
-
Transcription factor RORalpha is critical for nuocyte development
-
Wong SH, Walker JA, Jolin HE, Drynan LF, Hams E, Camelo A, Barlow JL, Neill DR, Panova V, Koch U, Radtke F, Hardman CS, Hwang YY, Fallon PG, McKenzie AN (2012) Transcription factor RORalpha is critical for nuocyte development. Nat Immunol 13:229–236
-
(2012)
Nat Immunol
, vol.13
, pp. 229-236
-
-
Wong, S.H.1
Walker, J.A.2
Jolin, H.E.3
Drynan, L.F.4
Hams, E.5
Camelo, A.6
Barlow, J.L.7
Neill, D.R.8
Panova, V.9
Koch, U.10
Radtke, F.11
Hardman, C.S.12
Hwang, Y.Y.13
Fallon, P.G.14
Mc Kenzie, A.N.15
-
105
-
-
84878578156
-
Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo
-
Wu X, Satpathy AT, Kc W, Liu P, Murphy TL, Murphy KM (2013) Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo. PLoS One 8:64-800
-
(2013)
PLoS One
, vol.8
, pp. 64-800
-
-
Wu, X.1
Satpathy, A.T.2
Kc, W.3
Liu, P.4
Murphy, T.L.5
Murphy, K.M.6
-
106
-
-
84876465574
-
E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment
-
Xu W, Carr T, Ramirez K, Mc Gregor S, Sigvardsson M, Kee BL (2013) E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment. Blood 121:1534–1542
-
(2013)
Blood
, vol.121
, pp. 1534-1542
-
-
Xu, W.1
Carr, T.2
Ramirez, K.3
Mc Gregor, S.4
Sigvardsson, M.5
Kee, B.L.6
-
107
-
-
84883428326
-
Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells
-
Yamamoto R, Morita Y, Ooehara J, Hamanaka S, Onodera M, Rudolph KL, Ema H, Nakauchi H (2013) Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells. Cell 154:1112–1126
-
(2013)
Cell
, vol.154
, pp. 1112-1126
-
-
Yamamoto, R.1
Morita, Y.2
Ooehara, J.3
Hamanaka, S.4
Onodera, M.5
Rudolph, K.L.6
Ema, H.7
Nakauchi, H.8
-
108
-
-
15944363056
-
Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3—short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients
-
Yang L, Bryder D, Adolfsson J, Nygren J, Mansson R, Sigvardsson M, Jacobsen SE (2005) Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3—short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients. Blood 105:2717–2723
-
(2005)
Blood
, vol.105
, pp. 2717-2723
-
-
Yang, L.1
Bryder, D.2
Adolfsson, J.3
Nygren, J.4
Mansson, R.5
Sigvardsson, M.6
Jacobsen, S.E.7
-
110
-
-
84876762753
-
T cell factor 1 is required for group 2 innate lymphoid cell generation
-
Yang Q, Monticelli LA, Saenz SA, Chi AW, Sonnenberg GF, Tang J, de Obaldia ME, Bailis W, Bryson JL, Toscano K, Huang J, Haczku A, Pear WS, Artis D, Bhandoola A (2013) T cell factor 1 is required for group 2 innate lymphoid cell generation. Immunity 38:694–704
-
(2013)
Immunity
, vol.38
, pp. 694-704
-
-
Yang, Q.1
Monticelli, L.A.2
Saenz, S.A.3
Chi, A.W.4
Sonnenberg, G.F.5
Tang, J.6
De Obaldia, M.E.7
Bailis, W.8
Bryson, J.L.9
Toscano, K.10
Huang, J.11
Haczku, A.12
Pear, W.S.13
Artis, D.14
Bhandoola, A.15
-
111
-
-
82755186810
-
Cutting edge: Natural helper cells derive from lymphoid progenitors
-
Yang Q, Saenz SA, Zlotoff DA, Artis D, Bhandoola A (2011) Cutting edge: natural helper cells derive from lymphoid progenitors. J Immunol 187:5505–5509
-
(2011)
J Immunol
, vol.187
, pp. 5505-5509
-
-
Yang, Q.1
Saenz, S.A.2
Zlotoff, D.A.3
Artis, D.4
Bhandoola, A.5
-
112
-
-
67650588402
-
Pre-TCR signaling inactivates notch1 transcription by antagonizing E2A
-
Yashiro-Ohtani Y, He Y, Ohtani T, Jones ME, Shestova O, Xu L, Fang TC, Chiang MY, Intlekofer AM, Blacklow SC, Zhuang Y, Pear WS (2009) Pre-TCR signaling inactivates notch1 transcription by antagonizing E2A. Genes Dev 23:1665–1676
-
(2009)
Genes Dev
, vol.23
, pp. 1665-1676
-
-
Yashiro-Ohtani, Y.1
He, Y.2
Ohtani, T.3
Jones, M.E.4
Shestova, O.5
Xu, L.6
Fang, T.C.7
Chiang, M.Y.8
Intlekofer, A.M.9
Blacklow, S.C.10
Zhuang, Y.11
Pear, W.S.12
-
113
-
-
84869168809
-
The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy
-
Yu S, Zhou X, Steinke FC, Liu C, Chen SC, Zagorodna O, Jing X, Yokota Y, Meyerholz DK, Mullighan CG, Knudson CM, Zhao DM, Xue HH (2012) The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy. Immunity 37:813–826
-
(2012)
Immunity
, vol.37
, pp. 813-826
-
-
Yu, S.1
Zhou, X.2
Steinke, F.C.3
Liu, C.4
Chen, S.C.5
Zagorodna, O.6
Jing, X.7
Yokota, Y.8
Meyerholz, D.K.9
Mullighan, C.G.10
Knudson, C.M.11
Zhao, D.M.12
Xue, H.H.13
-
114
-
-
84875761924
-
Exploring the RNA world in hematopoietic cells through the lens of RNA-binding proteins
-
Yuan J, Muljo SA (2013) Exploring the RNA world in hematopoietic cells through the lens of RNA-binding proteins. Immunol Rev 253:290–303
-
(2013)
Immunol Rev
, vol.253
, pp. 290-303
-
-
Yuan, J.1
Muljo, S.A.2
-
115
-
-
77958542905
-
Load and lock: The molecular mechanisms of B-lymphocyte commitment
-
Zandi S, Bryder D, Sigvardsson M (2010) Load and lock: the molecular mechanisms of B-lymphocyte commitment. Immunol Rev 238:47–62
-
(2010)
Immunol Rev
, vol.238
, pp. 47-62
-
-
Zandi, S.1
Bryder, D.2
Sigvardsson, M.3
-
116
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W, Flavell RA (1997) The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89:587–596
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
117
-
-
9244263631
-
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses
-
Zhu J, Min B, Hu-Li J, Watson CJ, Grinberg A, Wang Q, Killeen N, Urban JF, Guo L, PAUL WE (2004) Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat Immunol 5:1157–1165
-
(2004)
Nat Immunol
, vol.5
, pp. 1157-1165
-
-
Zhu, J.1
Min, B.2
Hu-Mi, J.3
Watson, C.J.4
Grinberg, A.5
Wang, Q.6
Killeen, N.7
Urban, J.F.8
Guo, L.9
Paul, W.E.10
|