Selective phosphorylation of the Dlg1AB variant is critical for TCR-induced p38 activation and induction of proinflammatory cytokines in CD8+ T cells

Journal of Immunology

Volumn 193, Issue 6, 2014, Pages 2651-2660

  Crocetti, Jillian ^a   Silva, Oscar ^a   Humphries, Lisa A ^a,b   Tibbs, Michelle D ^a   Miceli, M Carrie ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SCAFFOLD PROTEIN; SCAFFOLD PROTEIN DLG1AB; SCAFFOLD PROTEIN DLG1B; SYNAPTOPHYSIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; CYTOKINE; ISOPROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; NERVE PROTEIN; PROTEIN KINASE LCK; SAPAP PROTEINS; TYROSINE;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CD8+ T LYMPHOCYTE; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; GENE EXPRESSION; IMMUNITY; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL COMMUNICATION; CHEMISTRY; GENETICS; IMMUNOLOGY; INFLAMMATION; LYMPHOCYTE ACTIVATION; METABOLISM; PHOSPHORYLATION; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CYTOKINES; ENZYME ACTIVATION; INFLAMMATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN ISOFORMS; RECEPTORS, ANTIGEN, T-CELL; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TYROSINE;

EID: 84921641429     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401196     Document Type: Article

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