-
1
-
-
0034642499
-
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
-
Bachmaier, K., C. Krawczyk, I. Kozieradzki, Y. Y. Kong, T. Sasaki, A. Oliveira-dos Santos, S. Mariathasan, D. Bouchard, A. Wakeham, A. Itie, J. Le, P. S. Ohashi, I. Sarosi, H. Nishina, S. Lipkowitz, and J. M. Penninger. 2000. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature 403:211-216.
-
(2000)
Nature
, vol.403
, pp. 211-216
-
-
Bachmaier, K.1
Krawczyk, C.2
Kozieradzki, I.3
Kong, Y.Y.4
Sasaki, T.5
Oliveira-dos Santos, A.6
Mariathasan, S.7
Bouchard, D.8
Wakeham, A.9
Itie, A.10
Le, J.11
Ohashi, P.S.12
Sarosi, I.13
Nishina, H.14
Lipkowitz, S.15
Penninger, J.M.16
-
2
-
-
0037456795
-
-
Betschinger, J., K. Mechtler, and J. A. Knoblich. 2003. The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature 422:326-330.
-
Betschinger, J., K. Mechtler, and J. A. Knoblich. 2003. The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature 422:326-330.
-
-
-
-
3
-
-
0036369804
-
Genetic studies define MAGUK proteins as regulators of epithelial cell polarity
-
Caruana, G. 2002. Genetic studies define MAGUK proteins as regulators of epithelial cell polarity. Int. J. Dev. Biol. 46:511-518.
-
(2002)
Int. J. Dev. Biol
, vol.46
, pp. 511-518
-
-
Caruana, G.1
-
4
-
-
0033230122
-
Signaling pathways are focused at specialized regions of the plasma membrane by scaffolding proteins of the MAGUK family
-
Dimitratos, S. D., D. F. Woods, D. G. Stathakis, and P. J. Bryant. 1999. Signaling pathways are focused at specialized regions of the plasma membrane by scaffolding proteins of the MAGUK family. Bioessays 21:912-921.
-
(1999)
Bioessays
, vol.21
, pp. 912-921
-
-
Dimitratos, S.D.1
Woods, D.F.2
Stathakis, D.G.3
Bryant, P.J.4
-
5
-
-
0037434790
-
Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity
-
Etienne-Manneville, S., and A. Hall. 2003. Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity. Nature 421:753-756.
-
(2003)
Nature
, vol.421
, pp. 753-756
-
-
Etienne-Manneville, S.1
Hall, A.2
-
6
-
-
10744222965
-
Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells
-
Fujikawa, K., A. V. Miletic, F. W. Alt, R. Faccio, T. Brown, J. Hoog, J. Fredericks, S. Nishi, S. Mildiner, S. L. Moores, J. Brugge, F. S. Rosen, and W. Swat. 2003. Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells. J. Exp. Med. 198:1595-1608.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1595-1608
-
-
Fujikawa, K.1
Miletic, A.V.2
Alt, F.W.3
Faccio, R.4
Brown, T.5
Hoog, J.6
Fredericks, J.7
Nishi, S.8
Mildiner, S.9
Moores, S.L.10
Brugge, J.11
Rosen, F.S.12
Swat, W.13
-
7
-
-
22244455455
-
Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions
-
Funke, L., S. Dakoji, and D. S. Bredt. 2005. Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions. Annu. Rev. Biochem. 74:219-245.
-
(2005)
Annu. Rev. Biochem
, vol.74
, pp. 219-245
-
-
Funke, L.1
Dakoji, S.2
Bredt, D.S.3
-
8
-
-
33746731130
-
A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands
-
Giallourakis, C., Z. Cao, T. Green, H. Wachtel, X. Xie, M. Lopez-Illasaca, M. Daly, J. Rioux, and R. Xavier. 2006. A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands. Genome Res. 16:1056-1072.
-
(2006)
Genome Res
, vol.16
, pp. 1056-1072
-
-
Giallourakis, C.1
Cao, Z.2
Green, T.3
Wachtel, H.4
Xie, X.5
Lopez-Illasaca, M.6
Daly, M.7
Rioux, J.8
Xavier, R.9
-
9
-
-
34250004905
-
β-Catenin stabilization stalls the transition from double-positive to single positive stage and predisposes thymocytes to malignant transformation
-
Guo, Z., M. Dose, D. Kovalovsky, R. Chang, J. O'Neil, A. T. Look, H. von Boehmer, K. Khazaie, and F. Gounari. 2007. β-Catenin stabilization stalls the transition from double-positive to single positive stage and predisposes thymocytes to malignant transformation. Blood 109:5463-5472.
-
(2007)
Blood
, vol.109
, pp. 5463-5472
-
-
Guo, Z.1
Dose, M.2
Kovalovsky, D.3
Chang, R.4
O'Neil, J.5
Look, A.T.6
von Boehmer, H.7
Khazaie, K.8
Gounari, F.9
-
10
-
-
0030776844
-
Human homologue of the Drosophila discs large tumor suppressor binds to p561ck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes
-
Hanada, T., L. Lin, K. G. Chandy, S. S. Oh, and A. H. Chishti. 1997. Human homologue of the Drosophila discs large tumor suppressor binds to p561ck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes. J. Biol. Chem. 272:26899-26904.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 26899-26904
-
-
Hanada, T.1
Lin, L.2
Chandy, K.G.3
Oh, S.S.4
Chishti, A.H.5
-
11
-
-
0034666131
-
GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes
-
Hanada, T., L. Lin, E. V. Tibaldi, E. L. Reinherz, and A. H. Chishti. 2000. GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes. J. Biol. Chem. 275:28774-28784.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 28774-28784
-
-
Hanada, T.1
Lin, L.2
Tibaldi, E.V.3
Reinherz, E.L.4
Chishti, A.H.5
-
12
-
-
8644283766
-
The molecular adapter Carmal controls entry of IκB kinase into the central immune synapse
-
Hara, H., C. Bakal, T. Wada, D. Bouchard, R. Rottapel, T. Saito, and J. M. Penninger, 2004. The molecular adapter Carmal controls entry of IκB kinase into the central immune synapse. J. Exp. Med. 200:1167-1177.
-
(2004)
J. Exp. Med
, vol.200
, pp. 1167-1177
-
-
Hara, H.1
Bakal, C.2
Wada, T.3
Bouchard, D.4
Rottapel, R.5
Saito, T.6
Penninger, J.M.7
-
13
-
-
0037134787
-
Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95
-
Hering, H., and M. Sheng. 2002. Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95. FEBS Lett. 521:185-189.
-
(2002)
FEBS Lett
, vol.521
, pp. 185-189
-
-
Hering, H.1
Sheng, M.2
-
14
-
-
0034673760
-
Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2
-
Hsueh, Y. P., T. F. Wang, F. C. Yang, and M. Sheng. 2000. Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2. Nature 404:298-302.
-
(2000)
Nature
, vol.404
, pp. 298-302
-
-
Hsueh, Y.P.1
Wang, T.F.2
Yang, F.C.3
Sheng, M.4
-
15
-
-
0038795589
-
Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer
-
Humbert, P., S. Russell, and H. Richardson. 2003. Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer. Bioessays 25:542-553.
-
(2003)
Bioessays
, vol.25
, pp. 542-553
-
-
Humbert, P.1
Russell, S.2
Richardson, H.3
-
16
-
-
20444445916
-
A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation
-
Ludford-Menting, M. J., J. Oliaro, F. Sacirbegovic, E. T. Cheah, N. Pedersen, S. J. Thomas, A. Pasam, R. Iazzolino, L. E. Dow, N. J. Waterhouse, A. Murphy, S. Ellis, M. J. Smyth, M. H. Kershaw, P. K. Darcy, P. O. Humbert, and S. M. Russell. 2005. A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation. Immunity 22:737-748.
-
(2005)
Immunity
, vol.22
, pp. 737-748
-
-
Ludford-Menting, M.J.1
Oliaro, J.2
Sacirbegovic, F.3
Cheah, E.T.4
Pedersen, N.5
Thomas, S.J.6
Pasam, A.7
Iazzolino, R.8
Dow, L.E.9
Waterhouse, N.J.10
Murphy, A.11
Ellis, S.12
Smyth, M.J.13
Kershaw, M.H.14
Darcy, P.K.15
Humbert, P.O.16
Russell, S.M.17
-
17
-
-
33845930303
-
Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter
-
Mahoney, Z. X., B. Sammut, R. J. Xavier, J. Cunningham, G. Go, K. L. Brim, T. S. Stappenbeck, J. H. Miner, and W. Swat. 2006. Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter. Proc. Natl. Acad. Sci. USA 103:19872-19877.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 19872-19877
-
-
Mahoney, Z.X.1
Sammut, B.2
Xavier, R.J.3
Cunningham, J.4
Go, G.5
Brim, K.L.6
Stappenbeck, T.S.7
Miner, J.H.8
Swat, W.9
-
18
-
-
0032438114
-
Altered thymic positive selection and intracellular signals in Cbl-deficient mice
-
Naramura, M., H. K. Kole, R. J. Hu, and H. Gu. 1998. Altered thymic positive selection and intracellular signals in Cbl-deficient mice. Proc. Natl. Acad. Sci. USA 95:15547-15552.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15547-15552
-
-
Naramura, M.1
Kole, H.K.2
Hu, R.J.3
Gu, H.4
-
20
-
-
0034600901
-
Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3
-
Ohteki, T., M. Parsons, A. Zakarian, R. G. Jones, L. T. Nguyen, J. R. Woodgett, and P. S. Ohashi. 2000. Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3. J. Exp. Med. 192:99-104.
-
(2000)
J. Exp. Med
, vol.192
, pp. 99-104
-
-
Ohteki, T.1
Parsons, M.2
Zakarian, A.3
Jones, R.G.4
Nguyen, L.T.5
Woodgett, J.R.6
Ohashi, P.S.7
-
21
-
-
0033712944
-
Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte
-
Outram, S. V., A. Varas, C. V. Pepicelli, and T. Crompton. 2000. Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte. Immunity 13:187-197.
-
(2000)
Immunity
, vol.13
, pp. 187-197
-
-
Outram, S.V.1
Varas, A.2
Pepicelli, C.V.3
Crompton, T.4
-
22
-
-
25444446160
-
Biophysical and pharmacological aspects of K+ channels in T lymphocytes
-
Panyi, G. 2005. Biophysical and pharmacological aspects of K+ channels in T lymphocytes. Eur. Biophys. J. 34:515-529.
-
(2005)
Eur. Biophys. J
, vol.34
, pp. 515-529
-
-
Panyi, G.1
-
23
-
-
0037385561
-
A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl
-
Plant, P. J., J. P. Fawcett, D. C. Lin, A. D. Holdorf, K. Binns, S. Kulkarni, and T. Pawson. 2003. A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl. Nat. Cell Biol. 5:301-308.
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 301-308
-
-
Plant, P.J.1
Fawcett, J.P.2
Lin, D.C.3
Holdorf, A.D.4
Binns, K.5
Kulkarni, S.6
Pawson, T.7
-
24
-
-
33846514807
-
Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-κB transcription factors
-
Round, J. L., L. A. Humphries, T. Tomassian, P. Mittelstadt, M. Zhang, and M. C. Miceli. 2007. Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-κB transcription factors. Nat. Immunol. 8:154-161.
-
(2007)
Nat. Immunol
, vol.8
, pp. 154-161
-
-
Round, J.L.1
Humphries, L.A.2
Tomassian, T.3
Mittelstadt, P.4
Zhang, M.5
Miceli, M.C.6
-
25
-
-
13644268540
-
Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells
-
Round, J. L., T. Tomassian, M. Zhang, V. Patel, S. P. Schoenberger, and M. C. Miceli. 2005. Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells. J. Exp. Med. 201:419-430.
-
(2005)
J. Exp. Med
, vol.201
, pp. 419-430
-
-
Round, J.L.1
Tomassian, T.2
Zhang, M.3
Patel, V.4
Schoenberger, S.P.5
Miceli, M.C.6
-
26
-
-
0032572720
-
Csk controls antigen receptor-mediated development and selection of T-lineage cells
-
Schmedt, C., K. Saijo, T. Niidome, R. Kuhn, S. Aizawa, and A. Tarakhovsky. 1998. Csk controls antigen receptor-mediated development and selection of T-lineage cells. Nature 394:901-904.
-
(1998)
Nature
, vol.394
, pp. 901-904
-
-
Schmedt, C.1
Saijo, K.2
Niidome, T.3
Kuhn, R.4
Aizawa, S.5
Tarakhovsky, A.6
-
27
-
-
0034916230
-
PDZ domains and the organization of supramolecular complexes
-
Sheng, M., and C. Sala. 2001. PDZ domains and the organization of supramolecular complexes. Annu. Rev. Neurosci. 24:1-29.
-
(2001)
Annu. Rev. Neurosci
, vol.24
, pp. 1-29
-
-
Sheng, M.1
Sala, C.2
-
28
-
-
0021200413
-
-
Shultz, L. D., D. R. Coman, C. L. Bailey, W. G. Beamer, and C. L. Sidman. 1984. Viable motheaten, a new allele at the motheaten locus. I. Pathology. Am. J. Pathol. 116:179-192.
-
Shultz, L. D., D. R. Coman, C. L. Bailey, W. G. Beamer, and C. L. Sidman. 1984. "Viable motheaten," a new allele at the motheaten locus. I. Pathology. Am. J. Pathol. 116:179-192.
-
-
-
-
29
-
-
22044440293
-
T-cell generation by lymph node resident progenitor cells
-
Terra, R., I. Louis, R. Le Blanc, S. Ouellet, J. C. Zuniga-Pflucker, and C. Perreault. 2005. T-cell generation by lymph node resident progenitor cells. Blood 106:193-200.
-
(2005)
Blood
, vol.106
, pp. 193-200
-
-
Terra, R.1
Louis, I.2
Le Blanc, R.3
Ouellet, S.4
Zuniga-Pflucker, J.C.5
Perreault, C.6
-
30
-
-
26044480408
-
A CXCR4-dependent chemorepellent signal contributes to the emigration of mature single-positive CD4 cells from the fetal thymus
-
Vianello, F., P. Kraft, Y. T. Mok, W. K. Hart, N. White, and M. C. Poznansky. 2005. A CXCR4-dependent chemorepellent signal contributes to the emigration of mature single-positive CD4 cells from the fetal thymus. J. Immunol. 175:5115-5125.
-
(2005)
J. Immunol
, vol.175
, pp. 5115-5125
-
-
Vianello, F.1
Kraft, P.2
Mok, Y.T.3
Hart, W.K.4
White, N.5
Poznansky, M.C.6
-
31
-
-
33744791463
-
Wnt signaling: Is the party in the nucleus?
-
Willert, K., and K. A. Jones. 2006. Wnt signaling: is the party in the nucleus? Genes Dev. 20:1394-1404.
-
(2006)
Genes Dev
, vol.20
, pp. 1394-1404
-
-
Willert, K.1
Jones, K.A.2
-
32
-
-
4444382955
-
Discs large (Dlg1) complexes in lymphocyte activation
-
Xavier, R., S. Rabizadeh, K. Ishiguro, N. Andre, J. B. Ortiz, H. Wachtel, D. G. Morris, M. Lopez-Ilasaca, A. C. Shaw, W. Swat, and B. Seed. 2004. Discs large (Dlg1) complexes in lymphocyte activation. J. Cell Biol. 166:173- 178.
-
(2004)
J. Cell Biol
, vol.166
, pp. 173-178
-
-
Xavier, R.1
Rabizadeh, S.2
Ishiguro, K.3
Andre, N.4
Ortiz, J.B.5
Wachtel, H.6
Morris, D.G.7
Lopez-Ilasaca, M.8
Shaw, A.C.9
Swat, W.10
Seed, B.11
-
33
-
-
0038032917
-
Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity
-
Yamanaka, T., Y. Horikoshi, Y. Sugiyama, C. Ishiyama, A. Suzuki, T. Hirose, A. Iwamatsu, A. Shinohara, and S. Ohno. 2003. Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity. Curr. Biol. 13:734-743.
-
(2003)
Curr. Biol
, vol.13
, pp. 734-743
-
-
Yamanaka, T.1
Horikoshi, Y.2
Sugiyama, Y.3
Ishiyama, C.4
Suzuki, A.5
Hirose, T.6
Iwamatsu, A.7
Shinohara, A.8
Ohno, S.9
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