Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 5, 2012, Pages 1625-1630

  Zanin Zhorov, Alexandra ^a   Lin, Jiqiang ^a   Scher, Jose ^a   Kumari, Sudha ^a   Blair, David ^a   Hippen, Keli L ^b   Blazar, Bruce R ^b   Abramson, Steven B ^a   Lafaille, Juan J ^a   Dustin, Michael L ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Immunology; Supported planar bilayers; T cell receptor signaling

Indexed keywords

DISC LARGE HOMOLOG 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SCAFFOLD PROTEIN; T LYMPHOCYTE RECEPTOR; TENSIN; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL ISOLATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; LYMPHOCYTE FUNCTION; NEGATIVE FEEDBACK; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BLOTTING, WESTERN; FLOW CYTOMETRY; HUMANS; LYMPHOCYTE ACTIVATION; MICROSCOPY, FLUORESCENCE; RECEPTORS, ANTIGEN, T-CELL; RNA INTERFERENCE; T-LYMPHOCYTES, REGULATORY;

EID: 84863133195     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1110120109     Document Type: Article

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