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Volumn 36, Issue 1, 2012, Pages 142-152

Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8 + T Cell Phenotypes

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 INTEGRIN; BETA1 INTEGRIN; CD27 ANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CD45RA ANTIGEN; CD45RO ANTIGEN; CD57 ANTIGEN; CD69 ANTIGEN; CD7 ANTIGEN; CD8 ANTIGEN; CELL SURFACE MARKER; CHEMOKINE RECEPTOR CCR7; CYTOKINE; FLUORESCENT DYE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANZYME B; HLA DR ANTIGEN; INTERLEUKIN 2; L SELECTIN; LEUKOSIALIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PERFORIN; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 84856278095     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2012.01.002     Document Type: Article
Times cited : (472)

References (48)
  • 5
    • 77954674575 scopus 로고    scopus 로고
    • Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ Tcells is linked to antigen recognition and Tcell differentiation
    • Bengsch B., Seigel B., Ruhl M., Timm J., Kuntz M., Blum H.E., Pircher H., Thimme R. Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ Tcells is linked to antigen recognition and Tcell differentiation. PLoS Pathog. 2010, 6:e1000947.
    • (2010) PLoS Pathog. , vol.6
    • Bengsch, B.1    Seigel, B.2    Ruhl, M.3    Timm, J.4    Kuntz, M.5    Blum, H.E.6    Pircher, H.7    Thimme, R.8
  • 8
    • 0014251127 scopus 로고
    • Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells invitro; inhibition by isoantibody and by drugs
    • Brunner K.T., Mauel J., Cerottini J.C., Chapuis B. Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells invitro; inhibition by isoantibody and by drugs. Immunology 1968, 14:181-196.
    • (1968) Immunology , vol.14 , pp. 181-196
    • Brunner, K.T.1    Mauel, J.2    Cerottini, J.C.3    Chapuis, B.4
  • 11
    • 79960835109 scopus 로고    scopus 로고
    • Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis
    • Davis M.M., Altman J.D., Newell E.W. Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis. Nat. Rev. Immunol. 2011, 11:551-558.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 551-558
    • Davis, M.M.1    Altman, J.D.2    Newell, E.W.3
  • 16
    • 0032482176 scopus 로고    scopus 로고
    • Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
    • Gallimore A., Glithero A., Godkin A., Tissot A.C., Plückthun A., Elliott T., Hengartner H., Zinkernagel R. Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. J.Exp. Med. 1998, 187:1383-1393.
    • (1998) J.Exp. Med. , vol.187 , pp. 1383-1393
    • Gallimore, A.1    Glithero, A.2    Godkin, A.3    Tissot, A.C.4    Plückthun, A.5    Elliott, T.6    Hengartner, H.7    Zinkernagel, R.8
  • 21
    • 33745685146 scopus 로고    scopus 로고
    • Simultaneous assessment of antigen-stimulated cytokine production and memory subset composition of memory CD8 Tcells
    • Jabbari A., Harty J.T. Simultaneous assessment of antigen-stimulated cytokine production and memory subset composition of memory CD8 Tcells. J.Immunol. Methods 2006, 313:161-168.
    • (2006) J.Immunol. Methods , vol.313 , pp. 161-168
    • Jabbari, A.1    Harty, J.T.2
  • 22
    • 0003658046 scopus 로고
    • PCA with more than two variables
    • John Wiley and Sons, New York, J.E. Jackson (Ed.)
    • Jackson J.E. PCA with more than two variables. User's Guide to Principal Compoenent Analysis 1991, 26-62. John Wiley and Sons, New York. J.E. Jackson (Ed.).
    • (1991) User's Guide to Principal Compoenent Analysis , pp. 26-62
    • Jackson, J.E.1
  • 23
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 Tcells that give rise to long-lived memory cells
    • Kaech S.M., Tan J.T., Wherry E.J., Konieczny B.T., Surh C.D., Ahmed R. Selective expression of the interleukin 7 receptor identifies effector CD8 Tcells that give rise to long-lived memory cells. Nat. Immunol. 2003, 4:1191-1198.
    • (2003) Nat. Immunol. , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 25
    • 79958122357 scopus 로고    scopus 로고
    • A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar Tcells
    • Ma C., Fan R., Ahmad H., Shi Q., Comin-Anduix B., Chodon T., Koya R.C., Liu C.C., Kwong G.A., Radu C.G., et al. A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar Tcells. Nat. Med. 2011, 17:738-743.
    • (2011) Nat. Med. , vol.17 , pp. 738-743
    • Ma, C.1    Fan, R.2    Ahmad, H.3    Shi, Q.4    Comin-Anduix, B.5    Chodon, T.6    Koya, R.C.7    Liu, C.C.8    Kwong, G.A.9    Radu, C.G.10
  • 26
    • 78650531619 scopus 로고    scopus 로고
    • Living in a house of cards: re-evaluating CD8+ T-cell immune correlates against HIV
    • Makedonas G., Betts M.R. Living in a house of cards: re-evaluating CD8+ T-cell immune correlates against HIV. Immunol. Rev. 2011, 239:109-124.
    • (2011) Immunol. Rev. , vol.239 , pp. 109-124
    • Makedonas, G.1    Betts, M.R.2
  • 28
    • 0037825764 scopus 로고    scopus 로고
    • Large numbers of dysfunctional CD8+ Tlymphocytes bearing receptors for a single dominant CMV epitope in the very old
    • Ouyang Q., Wagner W.M., Wikby A., Walter S., Aubert G., Dodi A.I., Travers P., Pawelec G. Large numbers of dysfunctional CD8+ Tlymphocytes bearing receptors for a single dominant CMV epitope in the very old. J.Clin. Immunol. 2003, 23:247-257.
    • (2003) J.Clin. Immunol. , vol.23 , pp. 247-257
    • Ouyang, Q.1    Wagner, W.M.2    Wikby, A.3    Walter, S.4    Aubert, G.5    Dodi, A.I.6    Travers, P.7    Pawelec, G.8
  • 29
    • 85047699080 scopus 로고    scopus 로고
    • A new " Logicle" display method avoids deceptive effects of logarithmic scaling for low signals and compensated data
    • Parks D.R., Roederer M., Moore W.A. A new " Logicle" display method avoids deceptive effects of logarithmic scaling for low signals and compensated data. Cytometry A 2006, 69:541-551.
    • (2006) Cytometry A , vol.69 , pp. 541-551
    • Parks, D.R.1    Roederer, M.2    Moore, W.A.3
  • 32
    • 41149160165 scopus 로고    scopus 로고
    • Emergence of polyfunctional CD8+ Tcells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy
    • Rehr M., Cahenzli J., Haas A., Price D.A., Gostick E., Huber M., Karrer U., Oxenius A. Emergence of polyfunctional CD8+ Tcells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy. J.Virol. 2008, 82:3391-3404.
    • (2008) J.Virol. , vol.82 , pp. 3391-3404
    • Rehr, M.1    Cahenzli, J.2    Haas, A.3    Price, D.A.4    Gostick, E.5    Huber, M.6    Karrer, U.7    Oxenius, A.8
  • 33
    • 40449141013 scopus 로고    scopus 로고
    • What is principal component analysis?
    • Ringnér M. What is principal component analysis?. Nat. Biotechnol. 2008, 26:303-304.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 303-304
    • Ringnér, M.1
  • 37
    • 77951681614 scopus 로고    scopus 로고
    • Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation
    • Rutishauser R.L., Kaech S.M. Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation. Immunol. Rev. 2010, 235:219-233.
    • (2010) Immunol. Rev. , vol.235 , pp. 219-233
    • Rutishauser, R.L.1    Kaech, S.M.2
  • 38
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F., Lenig D., Förster R., Lipp M., Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999, 401:708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Förster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 39
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory Tcell subsets: function, generation, and maintenance
    • Sallusto F., Geginat J., Lanzavecchia A. Central memory and effector memory Tcell subsets: function, generation, and maintenance. Annu. Rev. Immunol. 2004, 22:745-763.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 745-763
    • Sallusto, F.1    Geginat, J.2    Lanzavecchia, A.3
  • 40
    • 41149096579 scopus 로고    scopus 로고
    • T-cell quality in memory and protection: implications for vaccine design
    • Seder R.A., Darrah P.A., Roederer M. T-cell quality in memory and protection: implications for vaccine design. Nat. Rev. Immunol. 2008, 8:247-258.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 247-258
    • Seder, R.A.1    Darrah, P.A.2    Roederer, M.3
  • 41
    • 0035884987 scopus 로고    scopus 로고
    • Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes
    • Sliz P., Michielin O., Cerottini J.C., Luescher I., Romero P., Karplus M., Wiley D.C. Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes. J.Immunol. 2001, 167:3276-3284.
    • (2001) J.Immunol. , vol.167 , pp. 3276-3284
    • Sliz, P.1    Michielin, O.2    Cerottini, J.C.3    Luescher, I.4    Romero, P.5    Karplus, M.6    Wiley, D.C.7
  • 42
    • 79961208153 scopus 로고    scopus 로고
    • CD8+ CD28- and CD8+ CD57+ Tcells and their role in health and disease
    • Strioga M., Pasukoniene V., Characiejus D. CD8+ CD28- and CD8+ CD57+ Tcells and their role in health and disease. Immunology 2011, 134:17-32.
    • (2011) Immunology , vol.134 , pp. 17-32
    • Strioga, M.1    Pasukoniene, V.2    Characiejus, D.3
  • 43
    • 33749130614 scopus 로고    scopus 로고
    • Three memory subsets of human CD8+ Tcells differently expressing three cytolytic effector molecules
    • Takata H., Takiguchi M. Three memory subsets of human CD8+ Tcells differently expressing three cytolytic effector molecules. J.Immunol. 2006, 177:4330-4340.
    • (2006) J.Immunol. , vol.177 , pp. 4330-4340
    • Takata, H.1    Takiguchi, M.2
  • 46
    • 0023940215 scopus 로고
    • Enumeration ofIFN-gamma-producing human lymphocytes by spot-ELISA. A method todetect lymphokine-producing lymphocytes at the single-cell level
    • Versteegen J.M., Logtenberg T., Ballieux R.E. Enumeration ofIFN-gamma-producing human lymphocytes by spot-ELISA. A method todetect lymphokine-producing lymphocytes at the single-cell level. J.Immunol. Methods 1988, 111:25-29.
    • (1988) J.Immunol. Methods , vol.111 , pp. 25-29
    • Versteegen, J.M.1    Logtenberg, T.2    Ballieux, R.E.3
  • 47
    • 0030891988 scopus 로고    scopus 로고
    • Determination of antigen-specific memory/effector CD4+ Tcell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency
    • Waldrop S.L., Pitcher C.J., Peterson D.M., Maino V.C., Picker L.J. Determination of antigen-specific memory/effector CD4+ Tcell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency. J.Clin. Invest. 1997, 99:1739-1750.
    • (1997) J.Clin. Invest. , vol.99 , pp. 1739-1750
    • Waldrop, S.L.1    Pitcher, C.J.2    Peterson, D.M.3    Maino, V.C.4    Picker, L.J.5


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