Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse

EMBO Journal

Volumn 29, Issue 14, 2010, Pages 2301-2314

  Lasserre, Rémi ^a,b   Charrin, Stéphanie ^a,b,g   Cuche, Céline ^a,b   Danckaert, Anne ^a   Thoulouze, Maria Isabel ^a,b   De Chaumont, Fabrice ^a,f   Duong, Tarn ^a,h   Perrault, Nathalie ^c,d,e   Varin Blank, Nadine ^c,d,e,h   Olivo Marin, Jean Christophe ^a,b   Etienne Manneville, Sandrine ^a,b   Arpin, Monique ^b,f   Di Bartolo, Vincenzo ^a,b   Alcover, Andrés ^a,b  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c INSTITUT COCHIN   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e INSERM   (France)

^f INSTITUT CURIE   (France)

^g HÔPITAL PAUL BROUSSE   (France)

^h UNIVERSITÉ PARIS 13   (France)

Author keywords

Dlg1; ezrin; immunological synapse; microclusters; microtubules

Indexed keywords

DLG1 PROTEIN; EZRIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SCAFFOLD PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; IMMUNOREGULATION; MICROFILAMENT; MICROTUBULE; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CYTOSKELETAL PROTEINS; ENZYME ACTIVATION; HUMANS; IMMUNOLOGICAL SYNAPSES; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICROTUBULES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 77954886643     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.127     Document Type: Article

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