Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum

Bioorganic and Medicinal Chemistry

Volumn 23, Issue 3, 2015, Pages 526-531

  Vullo, Daniela ^a   Del Prete, Sonia ^b   Fisher, Gillian M ^c   Andrews, Katherine T ^c   Poulsen, Sally Ann ^c   Capasso, Clemente ^b   Supuran, Claudiu T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b CNR   (Italy)

^c GRIFFITH UNIVERSITY   (Australia)

Author keywords

Carbonic anhydrase; Inhibitor; Plasmodium falciparum; Sulfamate; Sulfonamide; CA class enzyme

Indexed keywords

ACETAZOLAMIDE; BENZOLAMIDE; BRINZOLAMIDE; CARBONATE DEHYDRATASE; CELECOXIB; DICLOFENAMIDE; DORZOLAMIDE; ETHOXZOLAMIDE; HYDROCHLOROTHIAZIDE; INDISULAM; METHAZOLAMIDE; SULFONAMIDE; SULTIAME; TOPIRAMATE; VALDECOXIB; ZONISAMIDE; ANTIMALARIAL AGENT; CARBONATE DEHYDRATASE INHIBITOR;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; ENZYME INHIBITION; GROWTH INHIBITION; IN VITRO STUDY; MOLECULAR DYNAMICS; NONHUMAN; PARASITE IDENTIFICATION; PLASMODIUM FALCIPARUM; RESIDUE ANALYSIS; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

PLASMODIUM FALCIPARUM; PROTOZOA;

ANTIMALARIALS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 84921373698     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2014.12.009     Document Type: Article

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