Design, synthesis of 4-aminoquinoline-derived thiazolidines and their antimalarial activity and heme polymerization inhibition studies

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 28, Issue 3, 2013, Pages 619-626

  Solomon, V Raja ^a   Haq, W ^a   Srivastava, Kumkum ^a   Puri, Sunil K ^a   Katti, S B ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

4 Aminoquinoline; Antimalarial agents; CQ analogues; Heme polymerization

Indexed keywords

2 (2,6 DICHLORO PHENYL) THIAZOLIDINE 4 CARBOXYLIC ACID [2 (7 CHLOROQUINOLIN 4 YLAMINO) ETHYL] AMIDE HYDROCHLORIDE; 2 (4 CHLORO PHENYL) THIAZOLIDINE 4 CARBOXYLIC ACID [2 (7 CHLORO QUINOLININVIVO HYDROCHLORIDE; 4 AMINOQUINOLINE DERIVATIVE; ANTIMALARIAL AGENT; CHLORIDE; HEMATIN; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG; 2 (2,6 DICHLORO PHENYL) THIAZOLIDINE 4 CARBOXYLIC ACID [2 (7 CHLORO QUINOLININ 4 YLAMINO) ETHYL] AMIDE HYDROCHLORIDE; 2 (4 CHLORO PHENYL) THIAZOLIDINE 4 CARBOXYLIC ACID [2 (7 CHLORO QUINOLININ 4 YLAMINO) ETHYL] AMIDE HYDROCHLORIDE;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG INHIBITION; DRUG SYNTHESIS; DRUG TARGETING; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; POLYMERIZATION; PRIORITY JOURNAL; ANIMAL EXPERIMENT; ANIMAL MODEL; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; DRUG EFFICACY; HEME POLYMERIZATION; MALARIA; MINIMUM INHIBITORY CONCENTRATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

AMINOQUINOLINES; ANIMALS; ANTIMALARIALS; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HEME; HEMEPROTEINS; MALARIA; MICE; PLASMODIUM FALCIPARUM; POLYMERIZATION; THIAZOLIDINES;

PLASMODIUM FALCIPARUM; PLASMODIUM YOELII;

EID: 84875404408     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2012.666537     Document Type: Article

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