Synthesis and antimalarial activity of urenyl Bis-chalcone in vitro and in vivo

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 28, Issue 6, 2013, Pages 1267-1273

  Domínguez, José N ^a   Gamboa De Domínguez, Neira ^a   Rodrigues, Juan ^a   Acosta, María Eugenia ^a   Caraballo, Noris ^b   León, Caritza ^b  

^a UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^b Universidad Pedagogica Experimental Libertador Institute Pedagogico de Caracas   (Venezuela)

Author keywords

Antimalarial; Bis chalcone; Plasmodium berghei; Urenyl

Indexed keywords

1,1 BIS[(3',4' N (URENYLPHENYL) 3 (3'',4'',5'' TRIMETHOXYPHENYL)] 2 PROPEN 1 ONE; ANTIMALARIAL AGENT; CHALCONE DERIVATIVE; CHLOROQUINE; GLOBIN; HEMATIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; HYDROLYSIS; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM BERGHEI INFECTION; POLYMERIZATION; PRIORITY JOURNAL; SURVIVAL TIME;

ANIMALS; ANTIMALARIALS; CHALCONES; DOSE-RESPONSE RELATIONSHIP, DRUG; HEME; MALE; MICE; MICE, INBRED STRAINS; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PLASMODIUM BERGHEI; POLYMERIZATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84887477905     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2012.733383     Document Type: Article

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