Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

PLoS Medicine

Volumn 11, Issue 7, 2014, Pages

  Agnandji, Selidji Todagbe ^a,b   Lell, Bertrand ^a,b   Fernandes, José Francisco ^a,b   Abossolo, Béatrice Peggy ^a,b   Kabwende, Anita Lumeka ^a,b   Adegnika, Ayola Akim ^a,b   Mordmüller, Benjamin ^a,b   Issifou, Saadou ^a,b   Kremsner, Peter Gottfried ^a,b   Loembe, Marguerite Massinga ^a,b   Sacarlal, Jahit ^c,d   Aide, Pedro ^c,d   Madrid, Lola ^c,d   Lanaspa, Miguel ^c,d   Mandjate, Sofia ^c,d   Aponte, John J ^c,d   Bulo, Helder ^c,d   Nhama, Abel ^c,d   Macete, Eusébio ^c,d   Alonso, Pedro ^c,d   Abdulla, Salim ^e,f   Salim, Nahya ^e,f   Mtoro, Ali Takadir ^e,f   Mutani, Paul ^e,f   Tanner, Marcel ^e,f   Mavere, Caroline ^e,f   Mwangoka, Grace ^e,f   Lweno, Omar ^e,f   Juma, Omar Ali ^e,f   Shekalaghe, Seif ^e,f   Tinto, Halidou ^g,h   D'Alessandro, Umberto ^g,h   Sorgho, Hermann ^g,h   Valea, Innocent ^g,h   Ouédraogo, Jean Bosco ^g,h   Lompo, Palpouguini ^g,h   Diallo, Salou ^g,h   Traore, Ousmane ^g,h   Bassole, Armand ^g,h   Dao, Edgard ^g,h   Hamel, Mary J ⁱ   Kariuki, Simon ⁱ   Oneko, Martina ⁱ   Odero, Chris ⁱ   Otieno, Kephas ⁱ   Awino, Norbert ⁱ   Muturi Kioi, Vincent ⁱ   Omoto, Jackton ⁱ   Laserson, Kayla F ⁱ   Slutsker, Laurence ⁱ   Otieno, Walter ^j   Otieno, Lucas ^j   Otsyula, Nekoye ^j   Gondi, Stacey ^j   Otieno, Allan ^j   Ogutu, Bernhards ^j   Ochola, Jew ^j   Onyango, Irene ^j   Oyieko, Janet ^j   Njuguna, Patricia ^k   Chilengi, Roma ^k   Akoo, Pauline ^k   Kerubo, Christine ^k   Maingi, Charity ^k   Olotu, Ally ^k   Bejon, Philip ^k   Marsh, Kevin ^k   Mwabingu, Gabriel ^k   Gitaka, Jesse ^k   Owusu Agyei, Seth ^l,m   Asante, Kwaku Poku ^l,m   Boahen, Owusu ^l,m   Dosoo, David ^l,m   Adjei, George ^l,m   Adeniji, Elisha ^l,m   Yawson, Abena Kunadu ^l,m   Kayan, Kingsley ^l,m   Chandramohan, Daniel ^l,m   Greenwood, Brian ^l,m   Lusingu, John ^m,n,o   Gesase, Samwel ^m,n,o   Malabeja, Anangisye ^m,n,o   Abdul, Omari ^m,n,o   Mahende, Coline ^m,n,o   Liheluka, Edwin ^m,n,o   Lemnge, Martha ^m,n,o   Theander, Thor G ^m,n,o   Drakeley, Chris ^m,n,o   Mbwana, Joyce ^m,n,o   Ansong, Daniel ^p   Agbenyega, Tsiri ^p   Adjei, Samuel ^p   Boateng, Harry Owusu ^p   Rettig, Theresa ^p   Bawa, John ^p   Sylverken, Justice ^p   Sambian, David ^p   Sarfo, Anima ^p   Agyekum, Alex ^p   Martinson, Francis ^q   Hoffman, Irving ^q   Mvalo, Tisungane ^q   Kamthunzi, Portia ^q   Nkomo, Rutendo ^q   Tembo, Tapiwa ^q   Tsidya, Gerald Tegha Mercy ^q   Kilembe, Jane ^q   Chawinga, Chimwemwe ^q   Ballou, W Ripley ^r   Cohen, Joe ^r   Guerra, Yolanda ^r   Jongert, Erik ^r   Lapierre, Didier ^r   Leach, Amanda ^r   Lievens, Marc ^r   Ofori Anyinam, Opokua ^r   Olivier, Aurélie ^r   Vekemans, Johan ^r   Kaslow, David ^s   Leboulleux, Didier ^s   Savarese, Barbara ^s   Schellenberg, David ^s   more..

^a ALBERT SCHWEITZER HOSPITAL   (Gabon)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c Ministérioda Saúde   (Mozambique)

^d CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^e IFAKARA HEALTH INSTITUTE   (Tanzania)

^f SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^g Centre National de la Recherche Scientifique et Technologique   (Burkina Faso)

^h INSTITUTE OF TROPICAL MEDICINE   (Belgium)

ⁱ KEMRI CDC Public Health and Research Collaboration   (Kenya)

^j KEMRI Walter Reed Project   (Kenya)

^k KEMRI WELLCOME TRUST RESEARCH PROGRAMME   (Kenya)

^l KINTAMPO HEALTH RESEARCH CENTRE   (Ghana)

^m LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

ⁿ NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (Tanzania)

^o UNIVERSITY OF COPENHAGEN   (Denmark)

^p KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Ghana)

^q UNIVERSITY OF NORTH CAROLINA PROJECT   (Malawi)

^r GSK   (Belgium)

^s PATH Malaria Vaccine Initiative   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CIRCUMSPOROZOITE PROTEIN; MALARIA VACCINE; MENINGOCOCCUS VACCINE; RABIES VACCINE; RTS S AS01; UNCLASSIFIED DRUG;

ARTICLE; BED NET; BLOOD SMEAR; CEREBROSPINAL FLUID CULTURE; CHILD; CONTROLLED STUDY; DISEASE SURVEILLANCE; DISEASE TRANSMISSION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG SURVEILLANCE PROGRAM; ENZYME LINKED IMMUNOSORBENT ASSAY; HAEMOPHILUS INFLUENZAE; HOSPITALIZATION; HUMAN; IMMUNOGENICITY; INCIDENCE; INFANT; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MALARIA; MEDICAL DICTIONARY FOR REGULATORY ACTIVITIES; MENINGITIS; MULTICENTER STUDY; PARASITEMIA; PHASE 3 CLINICAL TRIAL; PLASMODIUM FALCIPARUM; PRESCHOOL CHILD; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SALMONELLA; STREPTOCOCCUS PNEUMONIAE; VACCINATION;

EID: 84905389306     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001685     Document Type: Article

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