Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter

Nature Communications

Volumn 5, Issue , 2014, Pages

  Grossmann, Nina ^a   Vakkasoglu, Ahmet S ^b   Hulpke, Sabine ^a   Abele, Rupert ^a   Gaudet, Rachelle ^b   Tampé, Robert ^a  

^a GOETHE UNIVERSITY   (Germany)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ASPARTIC ACID; HETERODIMER; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; ANTIGEN; PROTEIN TRANSLOCASE; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING (TAP);

ANTIGEN; GERM CELL; HYDROLYSIS; PEPTIDE; SUBSTRATE; TRANSLOCATION;

ACTIVE TRANSPORT; ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL SURFACE; CONCENTRATION (PARAMETERS); CRYSTAL STRUCTURE; CRYSTALLIZATION; DIMERIZATION; EC50; ENERGY TRANSFER; ENZYME ACTIVITY; HYDROGEN BOND; INSECT CELL; MEMBRANE TRANSPORT; MICHAELIS MENTEN KINETICS; NONHUMAN; PROTEIN BINDING; PROTEIN HYDROLYSIS; PROTEIN TRANSPORT; SEDIMENTATION; SEDIMENTATION RATE; ULTRACENTRIFUGATION; ANIMAL; ANIMAL MODEL; HYDROLYSIS; INSECT; METABOLISM; PHYSIOLOGY; RAT; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; DIMERIZATION; HYDROLYSIS; INSECTS; MODELS, ANIMAL; PROTEIN TRANSLOCATION SYSTEMS; RATS;

EID: 84921028041     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6419     Document Type: Article

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