Functional clustering of mutations in the dimer interface of the nucleotide binding folds of the sulfonylurea receptor

Journal of Biological Chemistry

Volumn 283, Issue 44, 2008, Pages 30322-30329

  Masia, Ricard ^a   Nichols, Colin G ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLOW INTERACTIONS; LAWS AND LEGISLATION; NUCLEOTIDES; OLIGOMERS; PROTEINS;

CHANNEL ACTIVITIES; CHANNEL REGULATIONS; DATA SUPPORTS; DIMER INTERFACES; FUNCTIONAL EFFECTS; HETERO DIMERS; INTACT CELLS; LOOP REGIONS; NUCLEOTIDE BINDINGS; SULFONYLUREA RECEPTORS;

NUCLEIC ACIDS;

ADENOSINE DIPHOSPHATE MAGNESIUM; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; CYSTEINE; DIMER; HETERODIMER; POTASSIUM CHANNEL; SULFONYLUREA RECEPTOR;

ANIMAL CELL; ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; GENETIC TRANSFECTION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE BINDING SITE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; SEQUENCE HOMOLOGY; VALIDITY;

ADENOSINE DIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CERCOPITHECUS AETHIOPS; COS CELLS; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DIMERIZATION; MODELS, MOLECULAR; MUTAGENESIS; MUTATION; NUCLEOTIDES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN BINDING; PROTEIN FOLDING; RECEPTORS, DRUG;

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 57649183334     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804318200     Document Type: Article

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