Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 30, 2014, Pages 11025-11030

  Hohl, Michael ^a   Hürlimann, Lea M ^a   Boḧm, Simon ^b   Schop̈pe, Jendrik ^a   Grütter, Markus G ^a   Bordignon, Enrica ^b,c   Seeger, Markus A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Allosteric communication; Membrane transport; X ray crystallography

Indexed keywords

ABC EXPORTER; ABC TRANSPORTER; ADENOSINE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ALANINE; ASPARTIC ACID; PURINE NUCLEOSIDE PHOSPHORYLASE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CROSS LINKING; ENZYME ACTIVITY; HYDROGEN BOND; HYDROLYSIS; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ALLOSTERIC COMMUNICATION; MEMBRANE TRANSPORT; X-RAY CRYSTALLOGRAPHY;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; ALLOSTERIC SITE; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT, ACTIVE; LACTOCOCCUS LACTIS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84905040016     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1400485111     Document Type: Article

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