The MHC I loading complex: A multitasking machinery in adaptive immunity

Trends in Biochemical Sciences

Volumn 38, Issue 8, 2013, Pages 412-420

  Hulpke, Sabine ^a   Tampé, Robert ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

ABC transporters; Chaperones; ER quality control; Macromolecular complexes; MHC class I molecules; Proteasome; Tapasin; Transporter associated with antigen processing

Indexed keywords

ABC TRANSPORTER; CALNEXIN; CALRETICULIN; CARRIER PROTEIN; CHAPERONE; CYCLIN DEPENDENT KINASE INHIBITOR 1C; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEINASE; TAPASIN; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 2; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; AMINO TERMINAL SEQUENCE; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CYTOTOXIC T LYMPHOCYTE; ENDOPLASMIC RETICULUM; HOST PATHOGEN INTERACTION; HUMAN; INNATE IMMUNITY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; STOICHIOMETRY;

ABC TRANSPORTERS; CHAPERONES; ER QUALITY CONTROL; MACROMOLECULAR COMPLEXES; MHC CLASS I MOLECULES; PROTEASOME; TAPASIN; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING;

ADAPTIVE IMMUNITY; ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; ENDOPLASMIC RETICULUM; GENES, MHC CLASS I; HUMANS; MODELS, BIOLOGICAL; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84880756901     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2013.06.003     Document Type: Review

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