Sequences in the nonconsensus nucleotide-binding domain of ABCG5/ABCG8 required for sterol transport

Journal of Biological Chemistry

Volumn 286, Issue 9, 2011, Pages 7308-7314

  Wang, Jin ^a   Grishin, Nick ^a   Kinch, Lisa ^a   Cohen, Jonathan C ^a,b   Hobbs, Helen H ^a,b   Xie, Xiao Song ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATES; ATP HYDROLYSIS; ATP-BINDING CASSETTE TRANSPORTERS; HEPATOCYTES; HETERODIMERS; HYPERCHOLESTEROLEMIA; NORMAL FUNCTION; NUCLEOTIDE-BINDING DOMAIN; PLANT STEROLS; STRUCTURAL REQUIREMENTS; SUBSTRATE SPECIFICITY; TRANSPORT ACTIVITY;

AMINO ACIDS; CHOLESTEROL; LIPIDS; NUCLEOTIDES;

ALCOHOLS;

ABC TRANSPORTER; ABC TRANSPORTER G5; ABC TRANSPORTER G8; ADENOSINE TRIPHOSPHATE; ASPARTIC ACID; CHOLESTEROL; GLUTAMINE; HISTIDINE; STEROL; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME SPECIFICITY; HYDROLYSIS; LIPID TRANSPORT; MOUSE; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MOTIF;

AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MEMBRANE; CHOLESTEROL; CONSERVED SEQUENCE; LIPOPROTEINS; LIVER; LIVER NEOPLASMS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RATS; STEROLS;

EID: 79953220143     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.210880     Document Type: Article

References (24)

1. Higgins, C. F. (1992) Annu. Rev. Cell Biol. 8, 67-113
2. Procko, E., O'Mara, M. L., Bennett, W. F., Tieleman, D. P., and Gaudet, R. (2009) FASEB J. 23, 1287-1302
3. Zhang, D. W., Graf, G. A., Gerard, R. D., Cohen, J. C., and Hobbs, H. H. (2006) J. Biol. Chem. 281, 4507-4516
4. Moody, J. E., and Thomas, P. J. (2005) J. Bioenerg. Biomembr. 37, 475-479
5. Oswald, C., Holland, I. B., and Schmitt, L. (2006) Naunyn-Schmiedeberg's Arch. Pharmacol. 372, 385-399
6. Locher, K. P., Lee, A. T., and Rees, D. C. (2002) Science 296, 1091-1098
7. Smith, P. C., Karpowich, N., Millen, L., Moody, J. E., Rosen, J., Thomas, P. J., and Hunt, J. F. (2002) Mol. Cell 10, 139-149
8. Procko, E., and Gaudet, R. (2009) Curr. Opin. Immunol. 21, 84-91
9. Berger, A. L., Ikuma, M., and Welsh, M. J. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 455-460
10. Chen, M., Abele, R., and Tampé, R. (2004) J. Biol. Chem. 279, 46073-46081
11. Yu, L., Hammer, R. E., Li-Hawkins, J., Von Bergmann, K., Lutjohann, D., Cohen, J. C., and Hobbs, H. H. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 16237-16242
12. Yu, L., Li-Hawkins, J., Hammer, R. E., Berge, K. E., Horton, J. D., Cohen, J. C., and Hobbs, H. H. (2002) J. Clin. Invest. 110, 671-680
13. Graf, G. A., Li, W. P., Gerard, R. D., Gelissen, I., White, A., Cohen, J. C., and Hobbs, H. H. (2002) J. Clin. Invest. 110, 659-669
14. Graf, G. A., Yu, L., Li, W. P., Gerard, R., Tuma, P. L., Cohen, J. C., and Hobbs, H. H. (2003) J. Biol. Chem. 278, 48275-48282
15. Berge, K. E., Tian, H., Graf, G. A., Yu, L., Grishin, N. V., Schultz, J., Kwiterovich, P., Shan, B., Barnes, R., and Hobbs, H. H. (2000) Science 290, 1771-1775
16. Wang, J., Sun, F., Zhang, D. W., Ma, Y., Xu, F., Belani, J. D., Cohen, J. C., Hobbs, H. H., and Xie, X. S. (2006) J. Biol. Chem. 281, 27894-27904
17. Wang, J., Zhang, D. W., Lei, Y., Xu, F., Cohen, J. C., Hobbs, H. H., and Xie, X. S. (2008) Biochemistry 47, 5194-5204
18. Yu, L., von Bergmann, K., Lutjohann, D., Hobbs, H. H., and Cohen, J. C. (2004) J. Lipid Res. 45, 301-307
19. Shyamala, V., Baichwal, V., Beall, E., and Ames, G. F. (1991) J. Biol. Chem. 266, 18714-18719
20. Ambudkar, S. V., Kim, I. W., Xia, D., and Sauna, Z. E. (2006) FEBS Lett. 580, 1049-1055
21. Aleksandrov, L., Aleksandrov, A. A., Chang, X. B., and Riordan, J. R. (2002) J. Biol. Chem. 277, 15419-15425
22. Ernst, R., Kueppers, P., Klein, C. M., Schwarzmueller, T., Kuchler, K., and Schmitt, L. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 5069-5074
23. Beaudet, L., Urbatsch, I. L., and Gros, P. (1998) Biochemistry 37, 9073-9082
24. Zaitseva, J., Jenewein, S., Jumpertz, T., Holland, I. B., and Schmitt, L. (2005) EMBO J. 24, 1901-1910