Therapeutic applications of extracellular vesicles: Clinical promise and open questions

Annual Review of Pharmacology and Toxicology

Volumn 55, Issue , 2015, Pages 439-464

  György, Bence ^a,b   Hung, Michelle E ^c   Breakefield, Xandra O ^a   Leonard, Joshua N ^d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d Northwestern University   (United States)

Author keywords

Drug delivery; Exosomes; Extracellular RNA; Gene medicine; Gene therapy; Liposomes; Mesenchymal stem cells; Microvesicles; Nanoparticles

Indexed keywords

CANCER VACCINE; ESCRT PROTEIN; LIPOSOME; MENINGOCOCCUS VACCINE; NANOPARTICLE; OLIGONUCLEOTIDE; DNA; DRUG; DRUG CARRIER; RNA; VACCINE;

BORDETELLA PERTUSSIS; CELL MEMBRANE; DENDRITIC CELL; EIMERIA TENELLA; EXOSOME; EXTRACELLULAR VESICLE; HISTOCOMPATIBILITY COMPLEX; IMMUNE RESPONSE; IMMUNOMODULATION; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MULTIVESICULAR BODY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; TOXOPLASMA GONDII; VACCINATION; ANIMAL; DRUG DESIGN; GENE TRANSFER; HUMAN; IMMUNOLOGY; MEDICINAL CHEMISTRY; MEMBRANE MICROPARTICLE; METABOLISM; NANOTECHNOLOGY; TISSUE DISTRIBUTION;

ANIMALS; CELL-DERIVED MICROPARTICLES; CHEMISTRY, PHARMACEUTICAL; DNA; DRUG CARRIERS; DRUG DESIGN; EXOSOMES; GENE TRANSFER TECHNIQUES; HUMANS; NANOPARTICLES; NANOTECHNOLOGY; PHARMACEUTICAL PREPARATIONS; RNA; TISSUE DISTRIBUTION; VACCINES;

EID: 84920767728     PISSN: 03621642     EISSN: 15454304     Source Type: Book Series    
DOI: 10.1146/annurev-pharmtox-010814-124630     Document Type: Review

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