-
1
-
-
0034740197
-
Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies
-
M.P. Lambert, K.L. Viola, B.A. Chromy, L. Chang, T.E. Morgan, J. Yu, D.L. Venton, G.A. Krafft, C.E. Finch, and W.L. Klein Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies J. Neurochem. 79 2001 595 605
-
(2001)
J. Neurochem.
, vol.79
, pp. 595-605
-
-
Lambert, M.P.1
Viola, K.L.2
Chromy, B.A.3
Chang, L.4
Morgan, T.E.5
Yu, J.6
Venton, D.L.7
Krafft, G.A.8
Finch, C.E.9
Klein, W.L.10
-
2
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
D.M. Walsh, I. Klyubin, J.V. Fadeeva, W.K. Cullen, R. Anwyl, M.S. Wolfe, M.J. Rowan, and D.J. Selkoe Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo Nature 416 2002 535 539
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
3
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
D. Schenk, R. Barbour, W. Dunn, G. Gordon, H. Grajeda, T. Guido, K. Hu, J. Huang, K. Johnson-Wood, K. Khan, D. Kholodenko, M. Lee, Z. Liao, I. Lieberburg, R. Motter, L. Mutter, F. Soriano, G. Shopp, N. Vasquez, C. Vandevert, S. Walker, M. Wogulis, T. Yednock, D. Games, and P. Seubert Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse Nature 400 1999 173 177
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
4
-
-
0034700471
-
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
C. Janus, J. Pearson, J. McLaurin, P.M. Mathews, Y. Jiang, S.D. Schmidt, M.A. Chishti, P. Horne, D. Heslin, J. French, H.T. Mount, R.A. Nixon, M. Mercken, C. Bergeron, P.E. Fraser, P. George-Hyslop, and D. Westaway A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease Nature 408 2000 979 982
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Horne, P.8
Heslin, D.9
French, J.10
Mount, H.T.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
George-Hyslop, P.16
Westaway, D.17
-
5
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
D. Morgan, D.M. Diamond, P.E. Gottschall, K.E. Ugen, C. Dickey, J. Hardy, K. Duff, P. Jantzen, G. DiCarlo, D. Wilcock, K. Connor, J. Hatcher, C. Hope, M. Gordon, and G.W. Arendash A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease Nature 408 2000 982 985
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
Duff, K.7
Jantzen, P.8
Dicarlo, G.9
Wilcock, D.10
Connor, K.11
Hatcher, J.12
Hope, C.13
Gordon, M.14
Arendash, G.W.15
-
6
-
-
0037203825
-
Nerve inflammation halts trial for Alzheimer's drug
-
E. Check Nerve inflammation halts trial for Alzheimer's drug Nature 415 2002 462
-
(2002)
Nature
, vol.415
, pp. 462
-
-
Check, E.1
-
7
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report
-
J.A. Nicoll, D. Wilkinson, C. Holmes, P. Steart, H. Markham, and R.O. Weller Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report Nat. Med. 9 2003 448 452
-
(2003)
Nat. Med.
, vol.9
, pp. 448-452
-
-
Nicoll, J.A.1
Wilkinson, D.2
Holmes, C.3
Steart, P.4
Markham, H.5
Weller, R.O.6
-
8
-
-
10744230547
-
Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
-
J.M. Orgogozo, S. Gilman, J.F. Dartigues, B. Laurent, M. Puel, L.C. Kirby, P. Jouanny, B. Dubois, L. Eisner, S. Flitman, B.F. Michel, M. Boada, A. Frank, and C. Hock Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization Neurology 61 2003 46 54
-
(2003)
Neurology
, vol.61
, pp. 46-54
-
-
Orgogozo, J.M.1
Gilman, S.2
Dartigues, J.F.3
Laurent, B.4
Puel, M.5
Kirby, L.C.6
Jouanny, P.7
Dubois, B.8
Eisner, L.9
Flitman, S.10
Michel, B.F.11
Boada, M.12
Frank, A.13
Hock, C.14
-
9
-
-
5644283479
-
Immunization of Alzheimer model mice with adenovirus vectors encoding amyloid beta-protein and GM-CSF reduces amyloid load in the brain
-
H.D. Kim, F.K. Kong, Y. Cao, T.L. Lewis, H. Kim, D.C. Tang, and K. Fukuchi Immunization of Alzheimer model mice with adenovirus vectors encoding amyloid beta-protein and GM-CSF reduces amyloid load in the brain Neurosci. Lett. 370 2004 218 223
-
(2004)
Neurosci. Lett.
, vol.370
, pp. 218-223
-
-
Kim, H.D.1
Kong, F.K.2
Cao, Y.3
Lewis, T.L.4
Kim, H.5
Tang, D.C.6
Fukuchi, K.7
-
10
-
-
16244379191
-
Induction of a Th2 immune response by co-administration of recombinant adenovirus vectors encoding amyloid beta-protein and GM-CSF
-
H.D. Kim, Y. Cao, F.K. Kong, K.R. Van Kampen, T.L. Lewis, Z. Ma, D.C. Tang, and K. Fukuchi Induction of a Th2 immune response by co-administration of recombinant adenovirus vectors encoding amyloid beta-protein and GM-CSF Vaccine 23 2005 2977 2986
-
(2005)
Vaccine
, vol.23
, pp. 2977-2986
-
-
Kim, H.D.1
Cao, Y.2
Kong, F.K.3
Van Kampen, K.R.4
Lewis, T.L.5
Ma, Z.6
Tang, D.C.7
Fukuchi, K.8
-
11
-
-
0036852750
-
Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis
-
J. McLaurin, R. Cecal, M.E. Kierstead, X. Tian, A.L. Phinney, M. Manea, J.E. French, M.H. Lambermon, A.A. Darabie, M.E. Brown, C. Janus, M.A. Chishti, P. Horne, D. Westaway, P.E. Fraser, H.T. Mount, M. Przybylski, and P. George-Hyslop Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis Nat. Med. 8 2002 1263 1269
-
(2002)
Nat. Med.
, vol.8
, pp. 1263-1269
-
-
McLaurin, J.1
Cecal, R.2
Kierstead, M.E.3
Tian, X.4
Phinney, A.L.5
Manea, M.6
French, J.E.7
Lambermon, M.H.8
Darabie, A.A.9
Brown, M.E.10
Janus, C.11
Chishti, M.A.12
Horne, P.13
Westaway, D.14
Fraser, P.E.15
Mount, H.T.16
Przybylski, M.17
George-Hyslop, P.18
-
12
-
-
0035854603
-
Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42
-
T. Town, J. Tan, N. Sansone, D. Obregon, T. Klein, and M. Mullan Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42 Neurosci. Lett. 307 2001 101 104
-
(2001)
Neurosci. Lett.
, vol.307
, pp. 101-104
-
-
Town, T.1
Tan, J.2
Sansone, N.3
Obregon, D.4
Klein, T.5
Mullan, M.6
-
13
-
-
0037384333
-
Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid
-
D.H. Cribbs, A. Ghochikyan, V. Vasilevko, M. Tran, I. Petrushina, N. Sadzikava, D. Babikyan, P. Kesslak, T. Kieber-Emmons, C.W. Cotman, and M.G. Agadjanyan Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid Int. Immunol. 15 2003 505 514
-
(2003)
Int. Immunol.
, vol.15
, pp. 505-514
-
-
Cribbs, D.H.1
Ghochikyan, A.2
Vasilevko, V.3
Tran, M.4
Petrushina, I.5
Sadzikava, N.6
Babikyan, D.7
Kesslak, P.8
Kieber-Emmons, T.9
Cotman, C.W.10
Agadjanyan, M.G.11
-
14
-
-
0034660891
-
Vaccination against gonadotropin-releasing hormone (GnRH) using toxin receptor-binding domain-conjugated GnRH repeats
-
C.T. Hsu, C.Y. Ting, C.J. Ting, T.Y. Chen, C.P. Lin, J. Whang-Peng, and J. Hwang Vaccination against gonadotropin-releasing hormone (GnRH) using toxin receptor-binding domain-conjugated GnRH repeats Cancer Res. 60 2000 3701 3705
-
(2000)
Cancer Res.
, vol.60
, pp. 3701-3705
-
-
Hsu, C.T.1
Ting, C.Y.2
Ting, C.J.3
Chen, T.Y.4
Lin, C.P.5
Whang-Peng, J.6
Hwang, J.7
-
15
-
-
0028111578
-
Overexpression of a C-terminal portion of the beta-amyloid precursor protein in mouse brains by transplantation of transformed neuronal cells
-
K.I. Fukuchi, D.D. Kunkel, P.A. Schwartzkroin, K. Kamino, C.E. Ogburn, C.E. Furlong, and G.M. Martin Overexpression of a C-terminal portion of the beta-amyloid precursor protein in mouse brains by transplantation of transformed neuronal cells Exp. Neurol. 127 1994 253 264
-
(1994)
Exp. Neurol.
, vol.127
, pp. 253-264
-
-
Fukuchi, K.I.1
Kunkel, D.D.2
Schwartzkroin, P.A.3
Kamino, K.4
Ogburn, C.E.5
Furlong, C.E.6
Martin, G.M.7
-
16
-
-
0031046583
-
Genetic immunotherapy of established tumors with adenovirus-murine granulocyte-macrophage colony-stimulating factor
-
C.T. Lee, S. Wu, I.F. Ciernik, H. Chen, S. Nadaf-Rahrov, D. Gabrilovich, and D.P. Carbone Genetic immunotherapy of established tumors with adenovirus-murine granulocyte-macrophage colony-stimulating factor Hum. Gene Ther. 8 1997 187 193
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 187-193
-
-
Lee, C.T.1
Wu, S.2
Ciernik, I.F.3
Chen, H.4
Nadaf-Rahrov, S.5
Gabrilovich, D.6
Carbone, D.P.7
-
17
-
-
0035164001
-
Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines
-
Z. Shi, M. Zeng, G. Yang, F. Siegel, L.J. Cain, K.R. Van Kampen, C.A. Elmets, and D.C. Tang Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines J. Virol. 75 2001 11474 11482
-
(2001)
J. Virol.
, vol.75
, pp. 11474-11482
-
-
Shi, Z.1
Zeng, M.2
Yang, G.3
Siegel, F.4
Cain, L.J.5
Van Kampen, K.R.6
Elmets, C.A.7
Tang, D.C.8
-
18
-
-
0031772229
-
Amyloid-beta deposition in skeletal muscle of transgenic mice: Possible model of inclusion body myopathy
-
K. Fukuchi, D. Pham, M. Hart, L. Li, and J.R. Lindsey Amyloid-beta deposition in skeletal muscle of transgenic mice: possible model of inclusion body myopathy Am. J. Pathol. 153 1998 1687 1693
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 1687-1693
-
-
Fukuchi, K.1
Pham, D.2
Hart, M.3
Li, L.4
Lindsey, J.R.5
-
19
-
-
8944228919
-
High levels of circulating beta-amyloid peptide do not cause cerebral beta-amyloidosis in transgenic mice
-
K. Fukuchi, L. Ho, S.G. Younkin, D.D. Kunkel, C.E. Ogburn, R.C. LeBoeuf, C.E. Furlong, S.S. Deeb, D. Nochlin, J. Wegiel, H.M. Wisniewski, and G.M. Martin High levels of circulating beta-amyloid peptide do not cause cerebral beta-amyloidosis in transgenic mice Am. J. Pathol. 149 1996 219 227
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 219-227
-
-
Fukuchi, K.1
Ho, L.2
Younkin, S.G.3
Kunkel, D.D.4
Ogburn, C.E.5
Leboeuf, R.C.6
Furlong, C.E.7
Deeb, S.S.8
Nochlin, D.9
Wegiel, J.10
Wisniewski, H.M.11
Martin, G.M.12
-
20
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: Evidence for augmentation of a 42-specific gamma secretase
-
J.L. Jankowsky, D.J. Fadale, J. Anderson, G.M. Xu, V. Gonzales, N.A. Jenkins, N.G. Copeland, M.K. Lee, L.H. Younkin, S.L. Wagner, S.G. Younkin, and D.R. Borchelt Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase Hum. Mol. Genet. 13 2004 159 170
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Lee, M.K.8
Younkin, L.H.9
Wagner, S.L.10
Younkin, S.G.11
Borchelt, D.R.12
-
21
-
-
0037073558
-
The generation and characterization of potentially therapeutic Abeta antibodies in mice: Differences according to strain and immunization protocol
-
E.T. Spooner, R.V. Desai, C. Mori, J.F. Leverone, and C.A. Lemere The generation and characterization of potentially therapeutic Abeta antibodies in mice: differences according to strain and immunization protocol Vaccine 21 2002 290 297
-
(2002)
Vaccine
, vol.21
, pp. 290-297
-
-
Spooner, E.T.1
Desai, R.V.2
Mori, C.3
Leverone, J.F.4
Lemere, C.A.5
-
22
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability
-
K.N. Dahlgren, A.M. Manelli, W.B. Stine Jr., L.K. Baker, G.A. Krafft, and M.J. LaDu Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability J. Biol. Chem. 277 2002 32046 32053
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr., W.B.3
Baker, L.K.4
Krafft, G.A.5
Ladu, M.J.6
-
23
-
-
18144380723
-
Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis
-
E.B. Lee, L.Z. Leng, V.M. Lee, and J.Q. Trojanowski Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis FEBS Lett. 579 2005 2564 2568
-
(2005)
FEBS Lett.
, vol.579
, pp. 2564-2568
-
-
Lee, E.B.1
Leng, L.Z.2
Lee, V.M.3
Trojanowski, J.Q.4
-
24
-
-
4644318756
-
Adenoviruses as vaccine vectors
-
N. Tatsis, and H.C. Ertl Adenoviruses as vaccine vectors Mol. Ther. 10 2004 616 629
-
(2004)
Mol. Ther.
, vol.10
, pp. 616-629
-
-
Tatsis, N.1
Ertl, H.C.2
-
26
-
-
1842336320
-
Vaccination onto bare skin
-
D.C. Tang, Z. Shi, and D.T. Curiel Vaccination onto bare skin Nature 388 1997 729 730
-
(1997)
Nature
, vol.388
, pp. 729-730
-
-
Tang, D.C.1
Shi, Z.2
Curiel, D.T.3
-
27
-
-
11144258882
-
Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans
-
K.R. Van Kampen, Z. Shi, P. Gao, J. Zhang, K.W. Foster, D.T. Chen, D. Marks, C.A. Elmets, and D.C. Tang Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans Vaccine 23 2005 1029 1036
-
(2005)
Vaccine
, vol.23
, pp. 1029-1036
-
-
Van Kampen, K.R.1
Shi, Z.2
Gao, P.3
Zhang, J.4
Foster, K.W.5
Chen, D.T.6
Marks, D.7
Elmets, C.A.8
Tang, D.C.9
-
28
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
F. Bard, C. Cannon, R. Barbour, R.L. Burke, D. Games, H. Grajeda, T. Guido, K. Hu, J. Huang, K. Johnson-Wood, K. Khan, D. Kholodenko, M. Lee, I. Lieberburg, R. Motter, M. Nguyen, F. Soriano, N. Vasquez, K. Weiss, B. Welch, P. Seubert, D. Schenk, and T. Yednock Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease Nat. Med. 6 2000 916 919
-
(2000)
Nat. Med.
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, M.13
Lieberburg, I.14
Motter, R.15
Nguyen, M.16
Soriano, F.17
Vasquez, N.18
Weiss, K.19
Welch, B.20
Seubert, P.21
Schenk, D.22
Yednock, T.23
more..
-
29
-
-
0037452779
-
Epitope and isotype specificities of antibodies to beta-amyloid peptide for protection against Alzheimer's disease-like neuropathology
-
F. Bard, R. Barbour, C. Cannon, R. Carretto, M. Fox, D. Games, T. Guido, K. Hoenow, K. Hu, K. Johnson-Wood, K. Khan, D. Kholodenko, C. Lee, M. Lee, R. Motter, M. Nguyen, A. Reed, D. Schenk, P. Tang, N. Vasquez, P. Seubert, and T. Yednock Epitope and isotype specificities of antibodies to beta-amyloid peptide for protection against Alzheimer's disease-like neuropathology Proc. Natl. Acad. Sci. USA 100 2003 2023 2028
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2023-2028
-
-
Bard, F.1
Barbour, R.2
Cannon, C.3
Carretto, R.4
Fox, M.5
Games, D.6
Guido, T.7
Hoenow, K.8
Hu, K.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, C.13
Lee, M.14
Motter, R.15
Nguyen, M.16
Reed, A.17
Schenk, D.18
Tang, P.19
Vasquez, N.20
Seubert, P.21
Yednock, T.22
more..
-
30
-
-
0037449117
-
Abeta1-15 is less immunogenic than Abeta1-40/42 for intranasal immunization of wild-type mice but may be effective for "boosting"
-
J.F. Leverone, E.T. Spooner, H.K. Lehman, J.D. Clements, and C.A. Lemere Abeta1-15 is less immunogenic than Abeta1-40/42 for intranasal immunization of wild-type mice but may be effective for "boosting" Vaccine 21 2003 2197 2206
-
(2003)
Vaccine
, vol.21
, pp. 2197-2206
-
-
Leverone, J.F.1
Spooner, E.T.2
Lehman, H.K.3
Clements, J.D.4
Lemere, C.A.5
-
31
-
-
0036860352
-
Intranasal immunotherapy for the treatment of Alzheimer's disease: Escherichia coli LT and LT(R192G) as mucosal adjuvants
-
C.A. Lemere, E.T. Spooner, J.F. Leverone, C. Mori, and J.D. Clements Intranasal immunotherapy for the treatment of Alzheimer's disease: Escherichia coli LT and LT(R192G) as mucosal adjuvants Neurobiol. Aging 23 2002 991 1000
-
(2002)
Neurobiol. Aging
, vol.23
, pp. 991-1000
-
-
Lemere, C.A.1
Spooner, E.T.2
Leverone, J.F.3
Mori, C.4
Clements, J.D.5
|