메뉴 건너뛰기




Volumn 21, Issue R1, 2012, Pages

Exosomes and microvesicles: Extracellular vesicles for genetic information transfer and gene therapy

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; SMALL INTERFERING RNA;

EID: 84867118648     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds317     Document Type: Article
Times cited : (769)

References (122)
  • 1
    • 0034682335 scopus 로고    scopus 로고
    • Lateral gene transfer and the nature of bacterial innovation
    • Ochman, H., Lawrence, J.G. and Groisman, E.A. (2000) Lateral gene transfer and the nature of bacterial innovation. Nature, 405, 299-304.
    • (2000) Nature , vol.405 , pp. 299-304
    • Ochman, H.1    Lawrence, J.G.2    Groisman, E.A.3
  • 2
    • 0033856775 scopus 로고    scopus 로고
    • Viral vectors for gene transfer: a review of their use in the treatment of human diseases
    • Walther, W. and Stein, U. (2000) Viral vectors for gene transfer: a review of their use in the treatment of human diseases. Drugs, 60, 249-271.
    • (2000) Drugs , vol.60 , pp. 249-271
    • Walther, W.1    Stein, U.2
  • 3
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi, H. (2007) Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol., 9, 654-659.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 654-659
    • Valadi, H.1
  • 4
    • 84866426167 scopus 로고    scopus 로고
    • Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? Front
    • Bellingham, S.A. and Hill, A.F. (2012) Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? Front. Physio., 3, 124.
    • (2012) Physio , vol.3 , pp. 124
    • Bellingham, S.A.1    Hill, A.F.2
  • 5
    • 71549122588 scopus 로고    scopus 로고
    • Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells
    • Hong, B.S. (2009) Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells. BMC Genomics, 10, 556.
    • (2009) BMC Genomics , vol.10 , pp. 556
    • Hong, B.S.1
  • 8
    • 79953858598 scopus 로고    scopus 로고
    • Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
    • Alvarez-Erviti, L. (2011) Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat. Biotechnol., 29, 341-345.
    • (2011) Nat. Biotechnol. , vol.29 , pp. 341-345
    • Alvarez-Erviti, L.1
  • 9
    • 84866941540 scopus 로고    scopus 로고
    • Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes
    • doi:10.1093/nar/gks463
    • Wahlgren, J. (2012) Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes. Nucleic Acids Res. doi:10.1093/nar/gks463.
    • (2012) Nucleic Acids Res
    • Wahlgren, J.1
  • 10
    • 0021719707 scopus 로고
    • Endocytosis and intracellular processing of transferrin and colloidal gold-transferrin in rat reticulocytes: demonstration of a pathway for receptor shedding
    • Harding, C., Heuser, J. and Stahl, P. (1984) Endocytosis and intracellular processing of transferrin and colloidal gold-transferrin in rat reticulocytes: demonstration of a pathway for receptor shedding. Eur. J. Cell Biol., 35, 256-263.
    • (1984) Eur. J. Cell Biol. , vol.35 , pp. 256-263
    • Harding, C.1    Heuser, J.2    Stahl, P.3
  • 11
    • 0020956787 scopus 로고
    • Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor
    • Pan, B.T. and Johnstone, R.M. (1983) Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Cell, 33, 967-978.
    • (1983) Cell , vol.33 , pp. 967-978
    • Pan, B.T.1    Johnstone, R.M.2
  • 13
    • 0030702085 scopus 로고    scopus 로고
    • The exosome: a conserved eukaryotic RNA processing complex containing multiple 3′ - 5′ exoribonucleases
    • Mitchell, P., Petfalski, E., Shevchenko, A., Mann, M. and Tollervey, D. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3′ -5′ exoribonucleases. Cell, 91, 457-466.
    • (1997) Cell , vol.91 , pp. 457-466
    • Mitchell, P.1    Petfalski, E.2    Shevchenko, A.3    Mann, M.4    Tollervey, D.5
  • 14
    • 84859515309 scopus 로고    scopus 로고
    • The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities
    • Pant, S., Hilton, H. and Burczynski, M.E. (2012) The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities. Biochem. Pharmacol., 83, 1484-1494.
    • (2012) Biochem. Pharmacol. , vol.83 , pp. 1484-1494
    • Pant, S.1    Hilton, H.2    Burczynski, M.E.3
  • 16
    • 84859098155 scopus 로고    scopus 로고
    • Vesicle formation within endosomes: an ESCRT marks the spot
    • Mayers, J.R. and Audhya, A. (2012) Vesicle formation within endosomes: an ESCRT marks the spot. Commun. Integr. Biol., 5, 50-56.
    • (2012) Commun. Integr. Biol. , vol.5 , pp. 50-56
    • Mayers, J.R.1    Audhya, A.2
  • 17
    • 7244260436 scopus 로고    scopus 로고
    • Exosome secretion: the art of reutilizing nonrecycled proteins?
    • de Gassart, A., Géminard, C., Hoekstra, D. and Vidal, M. (2004) Exosome secretion: the art of reutilizing nonrecycled proteins? Traffic, 5, 896-903.
    • (2004) Traffic , vol.5 , pp. 896-903
    • de Gassart, A.1    Géminard, C.2    Hoekstra, D.3    Vidal, M.4
  • 18
    • 63649086486 scopus 로고    scopus 로고
    • The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
    • Raiborg, C. and Stenmark, H. (2009) The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature, 458, 445-452.
    • (2009) Nature , vol.458 , pp. 445-452
    • Raiborg, C.1    Stenmark, H.2
  • 21
    • 84863199863 scopus 로고    scopus 로고
    • Get on the exosome bus with ALIX
    • Hurley, J.H. and Odorizzi, G. (2012) Get on the exosome bus with ALIX. Nat. Cell Biol., 14, 654-655.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 654-655
    • Hurley, J.H.1    Odorizzi, G.2
  • 22
    • 84858230240 scopus 로고    scopus 로고
    • Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein
    • Nabhan, J.F., Hu, R., Oh, R.S., Cohen, S.N. and Lu, Q. (2012) Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein. Proc. Natl Acad. Sci. USA, 109, 4146-4151.
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 4146-4151
    • Nabhan, J.F.1    Hu, R.2    Oh, R.S.3    Cohen, S.N.4    Lu, Q.5
  • 25
    • 33646146422 scopus 로고    scopus 로고
    • Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery
    • Ratajczak, J., Miekus, K., Kucia, M., Zhang, J., Reca, R., Dvorak, P. and Ratajczak, M.Z. (2006) Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia, 20, 847-856.
    • (2006) Leukemia , vol.20 , pp. 847-856
    • Ratajczak, J.1    Miekus, K.2    Kucia, M.3    Zhang, J.4    Reca, R.5    Dvorak, P.6    Ratajczak, M.Z.7
  • 26
    • 84859608013 scopus 로고    scopus 로고
    • Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells
    • Waldenström, A., Gennebäck, N., Hellman, U. and Ronquist, G. (2012) Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. PLoS One, 7, e34653.
    • (2012) PLoS One , vol.7
    • Waldenström, A.1    Gennebäck, N.2    Hellman, U.3    Ronquist, G.4
  • 28
    • 84862618600 scopus 로고    scopus 로고
    • Tumour-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers
    • D'Souza-Schorey, C. and Clancy, J.W. (2012) Tumour-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers. Genes Dev., 26, 1287-1299.
    • (2012) Genes Dev , vol.26 , pp. 1287-1299
    • D'Souza-Schorey, C.1    Clancy, J.W.2
  • 29
    • 77957091969 scopus 로고    scopus 로고
    • Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis
    • Kosaka, N., Iguchi, H. and Ochiya, T. (2010) Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis. Cancer Sci., 101, 2087-2092.
    • (2010) Cancer Sci , vol.101 , pp. 2087-2092
    • Kosaka, N.1    Iguchi, H.2    Ochiya, T.3
  • 32
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: composition, biogenesis and function
    • Théry, C., Zitvogel, L. and Amigorena, S. (2002) Exosomes: composition, biogenesis and function. Nat. Rev. Immunol., 2, 569-579.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 569-579
    • Théry, C.1    Zitvogel, L.2    Amigorena, S.3
  • 35
    • 77955643809 scopus 로고    scopus 로고
    • Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
    • Collino, F., Deregibus, M.C., Bruno, S., Sterpone, L., Aghemo, G., Viltono, L., Tetta, C. and Camussi, G. (2010) Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs. PLoS One, 5, e11803.
    • (2010) PLoS One , vol.5
    • Collino, F.1    Deregibus, M.C.2    Bruno, S.3    Sterpone, L.4    Aghemo, G.5    Viltono, L.6    Tetta, C.7    Camussi, G.8
  • 36
    • 69949117622 scopus 로고    scopus 로고
    • Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
    • Gibbings, D.J., Ciaudo, C., Erhardt, M. and Voinnet, O. (2009) Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat. Cell Biol., 11, 1143-1149.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 1143-1149
    • Gibbings, D.J.1    Ciaudo, C.2    Erhardt, M.3    Voinnet, O.4
  • 40
    • 2942749975 scopus 로고    scopus 로고
    • Hematopoietic stem cells convert into liver cells within days without fusion
    • Jang, Y.-Y., Collector, M.I., Baylin, S.B., Diehl, A.M. and Sharkis, S.J. (2004) Hematopoietic stem cells convert into liver cells within days without fusion. Nat. Cell Biol., 6, 532-539.
    • (2004) Nat. Cell Biol. , vol.6 , pp. 532-539
    • Jang, Y.-Y.1    Collector, M.I.2    Baylin, S.B.3    Diehl, A.M.4    Sharkis, S.J.5
  • 41
    • 34748870750 scopus 로고    scopus 로고
    • Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation
    • Aliotta, J.M., Sanchez-Guijo, F.M., Dooner, G.J., Johnson, K.W., Dooner, M.S., Greer, K.A., Greer, D., Pimentel, J., Kolankiewicz, L.M., Puente, N. et al. (2007) Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation. Stem Cells, 25, 2245-2256.
    • (2007) Stem Cells , vol.25 , pp. 2245-2256
    • Aliotta, J.M.1    Sanchez-Guijo, F.M.2    Dooner, G.J.3    Johnson, K.W.4    Dooner, M.S.5    Greer, K.A.6    Greer, D.7    Pimentel, J.8    Kolankiewicz, L.M.9    Puente, N.10
  • 42
    • 78650170923 scopus 로고    scopus 로고
    • Cellular phenotype switching and microvesicles
    • Quesenberry, P.J. and Aliotta, J.M. (2010) Cellular phenotype switching and microvesicles. Adv. Drug Deliv. Rev., 62, 1141-1148.
    • (2010) Adv. Drug Deliv. Rev. , vol.62 , pp. 1141-1148
    • Quesenberry, P.J.1    Aliotta, J.M.2
  • 43
    • 77049115799 scopus 로고    scopus 로고
    • Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription
    • Aliotta, J.M., Pereira, M., Johnson, K.W., de Paz, N., Dooner, M.S., Puente, N., Ayala, C., Brilliant, K., Berz, D., Lee, D. et al. (2010) Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription. Exp. Hematol., 38, 233-245.
    • (2010) Exp. Hematol. , vol.38 , pp. 233-245
    • Aliotta, J.M.1    Pereira, M.2    Johnson, K.W.3    de Paz, N.4    Dooner, M.S.5    Puente, N.6    Ayala, C.7    Brilliant, K.8    Berz, D.9    Lee, D.10
  • 46
    • 21544470261 scopus 로고    scopus 로고
    • Direct stimulation of nai{dotless}̈ve T cells by antigen-presenting cell vesicles
    • Sprent, J. (2005) Direct stimulation of nai{dotless}̈ve T cells by antigen-presenting cell vesicles. Blood Cells Mol. Dis., 35, 17-20.
    • (2005) Blood Cells Mol. Dis. , vol.35 , pp. 17-20
    • Sprent, J.1
  • 47
    • 0035863818 scopus 로고    scopus 로고
    • Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes
    • Skokos, D. (2001) Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. J. Immunol., 166, 868-876.
    • (2001) J. Immunol. , vol.166 , pp. 868-876
    • Skokos, D.1
  • 48
    • 0034771968 scopus 로고    scopus 로고
    • Tolerosomes are produced by intestinal epithelial cells
    • Karlsson, M. (2001) 'Tolerosomes' are produced by intestinal epithelial cells. Eur. J. Immunol., 31, 2892-2900.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 2892-2900
    • Karlsson, M.1
  • 49
    • 0037443410 scopus 로고    scopus 로고
    • Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo
    • Skokos, D., Botros, H.G., Demeure, C., Morin, J., Peronet, R., Birkenmeier, G., Boudaly, S. and Mécheri, S. (2003) Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. J. Immunol., 170, 3037- 3045.
    • (2003) J. Immunol. , vol.170 , pp. 3037-3045
    • Skokos, D.1    Botros, H.G.2    Demeure, C.3    Morin, J.4    Peronet, R.5    Birkenmeier, G.6    Boudaly, S.7    Mécheri, S.8
  • 50
    • 85009840654 scopus 로고    scopus 로고
    • Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells
    • Ekström, K., Valadi, H., Sjöstrand, M., Malmähll, C., Bossios, A., Eldh, M. and Lötvall, J. (2012) Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. J Extracellular Vesicles, 1, 18389.
    • (2012) J Extracellular Vesicles , vol.1 , pp. 18389
    • Ekström, K.1    Valadi, H.2    Sjöstrand, M.3    Malmhäll, C.4    Bossios, A.5    Eldh, M.6    Lötvall, J.7
  • 53
    • 77957037314 scopus 로고    scopus 로고
    • microRNA as a new immune-regulatory agent in breast milk
    • Kosaka, N., Izumi, H., Sekine, K. and Ochiya, T. (2010) microRNA as a new immune-regulatory agent in breast milk. Silence, 1, 7.
    • (2010) Silence , vol.1 , pp. 7
    • Kosaka, N.1    Izumi, H.2    Sekine, K.3    Ochiya, T.4
  • 54
    • 83655181807 scopus 로고    scopus 로고
    • Immune-related microRNAs are abundant in breast milk exosomes
    • doi:10.7150/ijbs.8.118
    • Zhou, Q. (2012) Immune-related microRNAs are abundant in breast milk exosomes. Int. J. Biol. Sci. 118. doi:10.7150/ijbs.8.118.
    • (2012) Int. J. Biol. Sci , pp. 118
    • Zhou, Q.1
  • 57
    • 38949191397 scopus 로고    scopus 로고
    • Exosomal transfer of proteins and RNAs at synapses in the nervous system
    • Smalheiser, N.R. (2007) Exosomal transfer of proteins and RNAs at synapses in the nervous system. Biol. Direct, 2, 35.
    • (2007) Biol. Direct , vol.2 , pp. 35
    • Smalheiser, N.R.1
  • 63
    • 0034710564 scopus 로고    scopus 로고
    • Endocytic entry of HIV-1
    • Fackler, O.T. and Peterlin, B.M. (2000) Endocytic entry of HIV-1. Curr. Biol., 10, 1005-1008.
    • (2000) Curr. Biol. , vol.10 , pp. 1005-1008
    • Fackler, O.T.1    Peterlin, B.M.2
  • 64
    • 0033929004 scopus 로고    scopus 로고
    • Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection
    • Mack, M., Kleinschmidt, A., Brühl, H., Klier, C., Nelson, P.J., Cihak, J., PlachÝ, J., Stangassinger, M., Erfle, V. and Schlöndorff, D. (2000) Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection. Nat. Med., 6, 769-775.
    • (2000) Nat. Med. , vol.6 , pp. 769-775
    • Mack, M.1    Kleinschmidt, A.2    Brühl, H.3    Klier, C.4    Nelson, P.J.5    Cihak, J.6    Plachý, J.7    Stangassinger, M.8    Erfle, V.9    Schlöndorff, D.10
  • 65
    • 0037414989 scopus 로고    scopus 로고
    • Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV
    • Rozmyslowicz, T., Majka, M., Kijowski, J., Murphy, S.L., Conover, D.O., Poncz, M., Ratajczak, J., Gaulton, G.N. and Ratajczak, M.Z. (2003) Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV. AIDS, 17, 33-42.
    • (2003) AIDS , vol.17 , pp. 33-42
    • Rozmyslowicz, T.1    Majka, M.2    Kijowski, J.3    Murphy, S.L.4    Conover, D.O.5    Poncz, M.6    Ratajczak, J.7    Gaulton, G.N.8    Ratajczak, M.Z.9
  • 67
    • 80053175966 scopus 로고    scopus 로고
    • Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
    • Yang, M., Chen, J., Su, F., Yu, B., Su, F., Lin, L., Liu, Y., Huang, J.-D. and Song, E. (2011) Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Mol. Cancer, 10, 117.
    • (2011) Mol. Cancer , vol.10 , pp. 117
    • Yang, M.1    Chen, J.2    Su, F.3    Yu, B.4    Su, F.5    Lin, L.6    Liu, Y.7    Huang, J.-D.8    Song, E.9
  • 68
    • 68549128599 scopus 로고    scopus 로고
    • Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors
    • Wysoczynski, M. and Ratajczak, M.Z. (2009) Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors. Int. J. Cancer, 125, 1595-1603.
    • (2009) Int. J. Cancer , vol.125 , pp. 1595-1603
    • Wysoczynski, M.1    Ratajczak, M.Z.2
  • 70
    • 77953142134 scopus 로고    scopus 로고
    • Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes
    • Park, J.E., Tan, H.S., Datta, A., Lai, R.C., Zhang, H., Meng, W., Lim, S.K. and Sze, S.K. (2010) Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol. Cell Proteomics, 9, 1085- 1099.
    • (2010) Mol. Cell Proteomics , vol.9 , pp. 1085-1099
    • Park, J.E.1    Tan, H.S.2    Datta, A.3    Lai, R.C.4    Zhang, H.5    Meng, W.6    Lim, S.K.7    Sze, S.K.8
  • 71
    • 0030779677 scopus 로고    scopus 로고
    • Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives
    • Mattson, M.P. (1997) Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives. Physiol. Rev., 77, 1081- 1132.
    • (1997) Physiol. Rev. , vol.77 , pp. 1081-1132
    • Mattson, M.P.1
  • 72
    • 0030433777 scopus 로고    scopus 로고
    • Cell biology of the beta-amyloid precursor protein and the genetics of Alzheimer's disease
    • Selkoe, D.J. (1996) Cell biology of the beta-amyloid precursor protein and the genetics of Alzheimer's disease. Cold Spring Harb. Symp. Quant. Biol., 61, 587-596.
    • (1996) Cold Spring Harb. Symp. Quant. Biol. , vol.61 , pp. 587-596
    • Selkoe, D.J.1
  • 73
    • 0029934134 scopus 로고    scopus 로고
    • Trafficking of cell-surface amyloid beta-protein precursor. II. Endocytosis, recycling and lysosomal targeting detected by immunolocalization
    • Yamazaki, T., Koo, E.H. and Selkoe, D.J. (1996) Trafficking of cell-surface amyloid beta-protein precursor. II. Endocytosis, recycling and lysosomal targeting detected by immunolocalization. J. Cell. Sci., 109 (Pt 5), 999-1008.
    • (1996) J. Cell. Sci. , vol.109 , Issue.PT 5 , pp. 999-1008
    • Yamazaki, T.1    Koo, E.H.2    Selkoe, D.J.3
  • 76
    • 43249087541 scopus 로고    scopus 로고
    • Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
    • Sharples, R.A., Vella, L.J., Nisbet, R.M., Naylor, R., Perez, K., Barnham, K.J., Masters, C.L., Hill, A.F. et al. (2008) Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes. FASEB J., 22, 1469-1478.
    • (2008) FASEB J , vol.22 , pp. 1469-1478
    • Sharples, R.A.1    Vella, L.J.2    Nisbet, R.M.3    Naylor, R.4    Perez, K.5    Barnham, K.J.6    Masters, C.L.7    Hill, A.F.8
  • 77
    • 43049160705 scopus 로고    scopus 로고
    • Exosomes: the Trojan horses of neurodegeneration
    • Ghidoni, R., Benussi, L. and Binetti, G. (2008) Exosomes: the Trojan horses of neurodegeneration. Med. Hypotheses, 70, 1226-1227.
    • (2008) Med. Hypotheses , vol.70 , pp. 1226-1227
    • Ghidoni, R.1    Benussi, L.2    Binetti, G.3
  • 78
    • 84856707794 scopus 로고    scopus 로고
    • Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease
    • Saman, S., Kim, W., Raya, M., Visnick, Y., Miro, S., Saman, S., Jackson, B., McKee, A.C., Alvarez, V.E., Lee, N.C.Y. et al. (2012) Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J. Biol. Chem., 287, 3842-3849.
    • (2012) J. Biol. Chem. , vol.287 , pp. 3842-3849
    • Saman, S.1    Kim, W.2    Raya, M.3    Visnick, Y.4    Miro, S.5    Saman, S.6    Jackson, B.7    McKee, A.C.8    Alvarez, V.E.9    Lee, N.C.Y.10
  • 79
    • 84862274671 scopus 로고    scopus 로고
    • Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD)
    • Wang, G., Dinkins, M., He, Q., Zhu, G., Poirier, C., Campbell, A., Mayer-Proschel, M. and Bieberich, E. (2012) Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD). J. Biol. Chem., 287, 21384-21395.
    • (2012) J. Biol. Chem. , vol.287 , pp. 21384-21395
    • Wang, G.1    Dinkins, M.2    He, Q.3    Zhu, G.4    Poirier, C.5    Campbell, A.6    Mayer-Proschel, M.7    Bieberich, E.8
  • 82
    • 84862230811 scopus 로고    scopus 로고
    • g-Synuclein: seeding of a-synuclein aggregation and transmission between cells
    • doi:10.1021/bi300478w
    • Surgucheva, I., Sharov, V.S. and Surguchov, A. (2012) g-Synuclein: seeding of a-synuclein aggregation and transmission between cells. Biochemistry. doi:10.1021/bi300478w.
    • (2012) Biochemistry
    • Surgucheva, I.1    Sharov, V.S.2    Surguchov, A.3
  • 83
    • 33947709328 scopus 로고    scopus 로고
    • Packaging of prions into exosomes is associated with a novel pathway of PrP processing
    • Vella, L.J., Sharples, R.A., Lawson, V.A., Masters, C.L., Cappai, R. and Hill, A.F. (2007) Packaging of prions into exosomes is associated with a novel pathway of PrP processing. J. Pathol., 211, 582-590.
    • (2007) J. Pathol. , vol.211 , pp. 582-590
    • Vella, L.J.1    Sharples, R.A.2    Lawson, V.A.3    Masters, C.L.4    Cappai, R.5    Hill, A.F.6
  • 84
    • 34948834742 scopus 로고    scopus 로고
    • Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA
    • Deregibus, M.C., Cantaluppi, V., Calogero, R., Lo Iacono, M., Tetta, C., Biancone, L., Bruno, S., Bussolati, B. and Camussi, G. (2007) Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA. Blood, 110, 2440-2448.
    • (2007) Blood , vol.110 , pp. 2440-2448
    • Deregibus, M.C.1    Cantaluppi, V.2    Calogero, R.3    Lo Iacono, M.4    Tetta, C.5    Biancone, L.6    Bruno, S.7    Bussolati, B.8    Camussi, G.9
  • 87
    • 84864530691 scopus 로고    scopus 로고
    • Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia-reperfusion injury by microRNA-dependent reprogramming of resident renal cells
    • doi:10.1038/ ki.2012.105
    • Cantaluppi, V., Gatti, S., Medica, D., Figliolini, F., Bruno, S., Deregibus, M.C., Sordi, A., Biancone, L., Tetta, C. and Camussi, G. (2012) Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia-reperfusion injury by microRNA-dependent reprogramming of resident renal cells. Kidney Int. doi:10.1038/ ki.2012.105.
    • (2012) Kidney Int
    • Cantaluppi, V.1    Gatti, S.2    Medica, D.3    Figliolini, F.4    Bruno, S.5    Deregibus, M.C.6    Sordi, A.7    Biancone, L.8    Tetta, C.9    Camussi, G.10
  • 89
    • 79955571241 scopus 로고    scopus 로고
    • Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury
    • Gatti, S., Bruno, S., Deregibus, M.C., Sordi, A., Cantaluppi, V., Tetta, C. and Camussi, G. (2011) Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury. Nephrol. Dial. Transplant., 26, 1474-1483.
    • (2011) Nephrol. Dial. Transplant. , vol.26 , pp. 1474-1483
    • Gatti, S.1    Bruno, S.2    Deregibus, M.C.3    Sordi, A.4    Cantaluppi, V.5    Tetta, C.6    Camussi, G.7
  • 92
    • 79960223740 scopus 로고    scopus 로고
    • Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease
    • Lai, R.C., Chen, T.S. and Lim, S.K. (2011) Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease. Regen Med, 6, 481-492.
    • (2011) Regen Med , vol.6 , pp. 481-492
    • Lai, R.C.1    Chen, T.S.2    Lim, S.K.3
  • 93
    • 75649119273 scopus 로고    scopus 로고
    • Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs
    • Chen, T.S., Lai, R.C., Lee, M.M., Choo, A.B.H., Lee, C.N. and Lim, S.K. (2010) Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs. Nucleic Acids Res., 38, 215-224.
    • (2010) Nucleic Acids Res , vol.38 , pp. 215-224
    • Chen, T.S.1    Lai, R.C.2    Lee, M.M.3    Choo, A.B.H.4    Lee, C.N.5    Lim, S.K.6
  • 94
    • 77958098024 scopus 로고    scopus 로고
    • Exosomes/microvesicles as a mechanism of cell-to-cell communication
    • Camussi, G., Deregibus, M.C., Bruno, S., Cantaluppi, V. and Biancone, L. (2010) Exosomes/microvesicles as a mechanism of cell-to-cell communication. Kidney Int., 78, 838-848.
    • (2010) Kidney Int , vol.78 , pp. 838-848
    • Camussi, G.1    Deregibus, M.C.2    Bruno, S.3    Cantaluppi, V.4    Biancone, L.5
  • 95
    • 84858783222 scopus 로고    scopus 로고
    • Lipid-based carriers of microRNAs and intercellular communication
    • Vickers, K.C. and Remaley, A.T. (2012) Lipid-based carriers of microRNAs and intercellular communication. Curr. Opin. Lipidol., 23, 91-97.
    • (2012) Curr. Opin. Lipidol. , vol.23 , pp. 91-97
    • Vickers, K.C.1    Remaley, A.T.2
  • 96
    • 0025409497 scopus 로고
    • Rabies virus binding to an acetylcholine receptor alpha-subunit peptide
    • Lentz, T.L. (1990) Rabies virus binding to an acetylcholine receptor alpha-subunit peptide. J. Mol. Recognit., 3, 82-88.
    • (1990) J. Mol. Recognit. , vol.3 , pp. 82-88
    • Lentz, T.L.1
  • 97
    • 43249109372 scopus 로고    scopus 로고
    • Isolation and characterization of exosomes from cell culture supernatants and biological fluids
    • Chapter 3, Unit 3.22
    • Théry, C., Amigorena, S., Raposo, G. and Clayton, A. (2006) Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol. Chapter 3, Unit 3.22.
    • (2006) Curr Protoc Cell Biol
    • Théry, C.1    Amigorena, S.2    Raposo, G.3    Clayton, A.4
  • 99
    • 84858037808 scopus 로고    scopus 로고
    • Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes
    • Tauro, B.J., Greening, D.W., Mathias, R.A., Ji, H., Mathivanan, S., Scott, A.M. and Simpson, R.J. (2012) Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Methods, 56, 293-304.
    • (2012) Methods , vol.56 , pp. 293-304
    • Tauro, B.J.1    Greening, D.W.2    Mathias, R.A.3    Ji, H.4    Mathivanan, S.5    Scott, A.M.6    Simpson, R.J.7
  • 102
    • 84866781675 scopus 로고    scopus 로고
    • Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry
    • van der Vlist, E.J., Nolte-'t Hoen, E.N.M., Stoorvogel, W., Arkesteijn, G.J.A. and Wauben, M.H.M. (2012) Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry. Nat. Protoc., 7, 1311-1326.
    • (2012) Nat. Protoc. , vol.7 , pp. 1311-1326
    • van der Vlist, E.J.1    Nolte-'t Hoen, E.N.M.2    Stoorvogel, W.3    Arkesteijn, G.J.A.4    Wauben, M.H.M.5
  • 104
    • 77957557995 scopus 로고    scopus 로고
    • Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome
    • Rood, I.M., Deegens, J.K.J., Merchant, M.L., Tamboer, W.P.M., Wilkey, D.W., Wetzels, J.F.M. and Klein, J.B. (2010) Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome. Kidney Int., 78, 810-816.
    • (2010) Kidney Int , vol.78 , pp. 810-816
    • Rood, I.M.1    Deegens, J.K.J.2    Merchant, M.L.3    Tamboer, W.P.M.4    Wilkey, D.W.5    Wetzels, J.F.M.6    Klein, J.B.7
  • 105
    • 84867117645 scopus 로고    scopus 로고
    • Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes
    • doi:10.1074/ mcp.M111.014845
    • Hosseini-Beheshti, E., Pham, S., Adomat, H., Li, N. and Guns, E.S. (2012) Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Mol. Cell. Proteomics. doi:10.1074/ mcp.M111.014845.
    • (2012) Mol. Cell. Proteomics.
    • Hosseini-Beheshti, E.1    Pham, S.2    Adomat, H.3    Li, N.4    Guns, E.S.5
  • 106
    • 79953243174 scopus 로고    scopus 로고
    • Exosomes as biomarker treasure chests for prostate cancer
    • Duijvesz, D., Luider, T., Bangma, C.H. and Jenster, G. (2011) Exosomes as biomarker treasure chests for prostate cancer. Eur. Urol., 59, 823- 831.
    • (2011) Eur. Urol. , vol.59 , pp. 823-831
    • Duijvesz, D.1    Luider, T.2    Bangma, C.H.3    Jenster, G.4
  • 107
    • 79954568598 scopus 로고    scopus 로고
    • Protein targeting to exosomes/microvesicles by plasma membrane anchors
    • Shen, B., Wu, N., Yang, J.-M. and Gould, S.J. (2011) Protein targeting to exosomes/microvesicles by plasma membrane anchors. J. Biol. Chem., 286, 14383-14395.
    • (2011) J. Biol. Chem. , vol.286 , pp. 14383-14395
    • Shen, B.1    Wu, N.2    Yang, J.-M.3    Gould, S.J.4
  • 110
    • 84862262370 scopus 로고    scopus 로고
    • Identification of nucleotide patterns enriched in secreted RNAs as putative cis-acting elements targeting them to exosome nano-vesicles
    • Batagov, A.O., Kuznetsov, V.A. and Kurochkin, I.V. (2011) Identification of nucleotide patterns enriched in secreted RNAs as putative cis-acting elements targeting them to exosome nano-vesicles. BMC Genomics, 12 (Suppl. 3), S18.
    • (2011) BMC Genomics , vol.12 , Issue.SUPPL. 3
    • Batagov, A.O.1    Kuznetsov, V.A.2    Kurochkin, I.V.3
  • 111
    • 78650722735 scopus 로고    scopus 로고
    • Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA
    • Eldh, M., Ekström, K., Valadi, H., Sjöstrand, M., Olsson, B., Jernås, M. and Lötvall, J. (2010) Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. PLoS One, 5, e15353.
    • (2010) PLoS One , vol.5
    • Eldh, M.1    Ekström, K.2    Valadi, H.3    Sjöstrand, M.4    Olsson, B.5    Jernås, M.6    Lötvall, J.7
  • 113
    • 79953081976 scopus 로고    scopus 로고
    • Interaction and uptake of exosomes by ovarian cancer cells
    • Escrevente, C., Keller, S., Altevogt, P. and Costa, J. (2011) Interaction and uptake of exosomes by ovarian cancer cells. BMC Cancer, 11, 108.
    • (2011) BMC Cancer , vol.11 , pp. 108
    • Escrevente, C.1    Keller, S.2    Altevogt, P.3    Costa, J.4
  • 114
    • 77957269172 scopus 로고    scopus 로고
    • Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy
    • Tian, T., Wang, Y., Wang, H., Zhu, Z. and Xiao, Z. (2010) Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy. J. Cell. Biochem., 111, 488-496.
    • (2010) J. Cell. Biochem. , vol.111 , pp. 488-496
    • Tian, T.1    Wang, Y.2    Wang, H.3    Zhu, Z.4    Xiao, Z.5
  • 115
    • 68849129712 scopus 로고    scopus 로고
    • Membrane vesicles as conveyors of immune responses
    • Théry, C., Ostrowski, M. and Segura, E. (2009) Membrane vesicles as conveyors of immune responses. Nat. Rev. Immunol., 9, 581-593.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 581-593
    • Théry, C.1    Ostrowski, M.2    Segura, E.3
  • 117
    • 79955481749 scopus 로고    scopus 로고
    • Exosomes as intercellular signalosomes and pharmacological effectors
    • Record, M., Subra, C., Silvente-Poirot, S. and Poirot, M. (2011) Exosomes as intercellular signalosomes and pharmacological effectors. Biochem. Pharmacol., 81, 1171-1182.
    • (2011) Biochem. Pharmacol. , vol.81 , pp. 1171-1182
    • Record, M.1    Subra, C.2    Silvente-Poirot, S.3    Poirot, M.4
  • 118
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: a review of programmed cell death
    • Elmore, S. (2007) Apoptosis: a review of programmed cell death. Toxicol. Pathol., 35, 495-516.
    • (2007) Toxicol. Pathol. , vol.35 , pp. 495-516
    • Elmore, S.1
  • 119
    • 3042738397 scopus 로고    scopus 로고
    • Neuronal apoptotic bodies: phagocytosis and degradation by primary microglial cells
    • Stolzing, A. and Grune, T. (2004) Neuronal apoptotic bodies: phagocytosis and degradation by primary microglial cells. FASEB J., 18, 743-745.
    • (2004) FASEB J , vol.18 , pp. 743-745
    • Stolzing, A.1    Grune, T.2
  • 120
    • 78649741781 scopus 로고    scopus 로고
    • Ectosomes as modulators of inflammation and immunity
    • Sadallah, S., Eken, C. and Schifferli, J.A. (2011) Ectosomes as modulators of inflammation and immunity. Clin. Exp. Immunol., 163, 26-32.
    • (2011) Clin. Exp. Immunol. , vol.163 , pp. 26-32
    • Sadallah, S.1    Eken, C.2    Schifferli, J.A.3
  • 121
    • 84858864047 scopus 로고    scopus 로고
    • Prostasomes are mediators of intercellular communication: from basic research to clinical implications
    • Ronquist, G. (2012) Prostasomes are mediators of intercellular communication: from basic research to clinical implications. J. Intern. Med., 271, 400-413.
    • (2012) J. Intern. Med. , vol.271 , pp. 400-413
    • Ronquist, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.