Phosphorylation of Smac by Akt promotes the caspase-3 activation during etoposide-induced apoptosis in HeLa cells

Molecular Carcinogenesis

Volumn 54, Issue 2, 2015, Pages 83-92

  Jeong, Chul Ho ^a   Chun, Kyung Soo ^a   Kundu, Juthika ^a   Park, Byoungduck ^a  

^a Keimyung University   (South Korea)

Author keywords

Akt; Apoptosis; Phosphorylation; Smac; XIAP

Indexed keywords

CASPASE 3; ETOPOSIDE; MUTANT PROTEIN; PROTEIN KINASE B; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE; X LINKED INHIBITOR OF APOPTOSIS; ANTINEOPLASTIC AGENT; DIABLO PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; SIGNAL PEPTIDE; XIAP PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CELL INTERACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME INDUCTION; ENZYME KINETICS; ENZYME PHOSPHORYLATION; HELA CELL LINE; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CELL PROLIFERATION; ETOPOSIDE; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIAL PROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SERINE; SIGNAL TRANSDUCTION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84920611709     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22075     Document Type: Article

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