-
1
-
-
84877628647
-
Autophagy in human health and disease
-
Choi AM, Ryter SW, Levine B. Autophagy in human health and disease. N Engl J Med. 2013;368(7):651-662.
-
(2013)
N Engl J Med.
, vol.368
, Issue.7
, pp. 651-662
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
2
-
-
84897143522
-
To be or not to be? How selective autophagy and cell death govern cell fate
-
Green DR, Levine B. To be or not to be? How selective autophagy and cell death govern cell fate. Cell. 2014;157(1):65-75.
-
(2014)
Cell.
, vol.157
, Issue.1
, pp. 65-75
-
-
Green, D.R.1
Levine, B.2
-
3
-
-
84886797274
-
Autophagy in infection, inflammation and immunity
-
Deretic V, Saitoh T, Akira S. Autophagy in infection, inflammation and immunity. Nat Rev Immunol. 2013;13(10):722-737.
-
(2013)
Nat Rev Immunol.
, vol.13
, Issue.10
, pp. 722-737
-
-
Deretic, V.1
Saitoh, T.2
Akira, S.3
-
4
-
-
37649005234
-
Autophagy in the patho-genesis of disease
-
Levine B, Kroemer G. Autophagy in the patho-genesis of disease. Cell. 2008;132(1):27-42.
-
(2008)
Cell.
, vol.132
, Issue.1
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
5
-
-
78751672975
-
Autoph-agy in immunity and inflammation
-
Levine B, Mizushima N, Virgin HW. Autoph-agy in immunity and inflammation. Nature. 2011;469(7330):323-335.
-
(2011)
Nature.
, vol.469
, Issue.7330
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
6
-
-
84919465425
-
Exo-somes and autophagy: Coordinated mechanisms for the maintenance of cellular fitness
-
Baixauli F, López-Otín C, Mittelbrunn M. Exo-somes and autophagy: coordinated mechanisms for the maintenance of cellular fitness. Fron t Immunol. 2014;5:403.
-
(2014)
Fron T Immunol.
, vol.5
, pp. 403
-
-
Baixauli, F.1
López-Otín, C.2
Mittelbrunn, M.3
-
7
-
-
84901833411
-
Autophagy and human disease: Emerging themes
-
Schneider JL, Cuervo AM. Autophagy and human disease: emerging themes. Curr Opin Genet Dev. 2014;26C:16-23.
-
(2014)
Curr Opin Genet Dev.
, vol.26 C
, pp. 16-23
-
-
Schneider, J.L.1
Cuervo, A.M.2
-
9
-
-
3042723794
-
Autophagy: Molecular mechanisms, physiological functions and relevance in human pathology
-
Marino G, Lopez-Otin C. Autophagy: molecular mechanisms, physiological functions and relevance in human pathology. Cell Mol Life Sci. 2004;61(12):1439-1454.
-
(2004)
Cell Mol Life Sci.
, vol.61
, Issue.12
, pp. 1439-1454
-
-
Marino, G.1
Lopez-Otin, C.2
-
10
-
-
78651423598
-
Microautophagy of cytosolic proteins by late endosomes
-
Sahu R, et al. Microautophagy of cytosolic proteins by late endosomes. Dev Cell. 2011;20(1):131-139.
-
(2011)
Dev Cell.
, vol.20
, Issue.1
, pp. 131-139
-
-
Sahu, R.1
-
11
-
-
84864318195
-
Chaperone-mediated autophagy: A unique way to enter the lysosome world
-
Kaushik S, Cuervo AM. Chaperone-mediated autophagy: a unique way to enter the lysosome world. Trends Cell Biol. 2012;22(8):407-417.
-
(2012)
Trends Cell Biol.
, vol.22
, Issue.8
, pp. 407-417
-
-
Kaushik, S.1
Cuervo, A.M.2
-
12
-
-
79955631150
-
Autophagy in the cellular energetic balance
-
Singh R, Cuervo AM. Autophagy in the cellular energetic balance. Cell Metab. 2011;13(5):495-504.
-
(2011)
Cell Metab.
, vol.13
, Issue.5
, pp. 495-504
-
-
Singh, R.1
Cuervo, A.M.2
-
13
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signaling regulation
-
Yang Z, Klionsky DJ. Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol. 2010;22(2):124-131.
-
(2010)
Curr Opin Cell Biol.
, vol.22
, Issue.2
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
14
-
-
84859366447
-
Protease signalling: The cutting edge
-
Turk B, Turk D, Turk V. Protease signalling: the cutting edge. EMBO J. 2012;31(7):1630-1643.
-
(2012)
EMBO J.
, vol.31
, Issue.7
, pp. 1630-1643
-
-
Turk, B.1
Turk, D.2
Turk, V.3
-
15
-
-
77950012622
-
The regulatory crosstalk between kinases and proteases in cancer
-
Lopez-Otin C, Hunter T. The regulatory crosstalk between kinases and proteases in cancer. Nat Rev Cancer. 2010;10(4):278-292.
-
(2010)
Nat Rev Cancer.
, vol.10
, Issue.4
, pp. 278-292
-
-
Lopez-Otin, C.1
Hunter, T.2
-
16
-
-
79952628267
-
The Beclin 1 network regulates autophagy and apoptosis
-
Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ. 2011;18(4):571-580.
-
(2011)
Cell Death Differ.
, vol.18
, Issue.4
, pp. 571-580
-
-
Kang, R.1
Zeh, H.J.2
Lotze, M.T.3
Tang, D.4
-
17
-
-
77950252174
-
Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
-
Djavaheri-Mergny M, Maiuri MC, Kroemer G. Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1. Oncogene. 2010;29(12):1717-1719.
-
(2010)
Oncogene.
, vol.29
, Issue.12
, pp. 1717-1719
-
-
Djavaheri-Mergny, M.1
Maiuri, M.C.2
Kroemer, G.3
-
18
-
-
33749162486
-
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
-
Yousefi S, et al. Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol. 2006;8(10):1124-1132.
-
(2006)
Nat Cell Biol.
, vol.8
, Issue.10
, pp. 1124-1132
-
-
Yousefi, S.1
-
19
-
-
78649251041
-
The in vitro cleavage of the hAtg proteins by cell death proteases
-
Norman JM, Cohen GM, Bampton ET. The in vitro cleavage of the hAtg proteins by cell death proteases. Au tophagy. 2010;6(8):1042-1056.
-
(2010)
Au Tophagy.
, vol.6
, Issue.8
, pp. 1042-1056
-
-
Norman, J.M.1
Cohen, G.M.2
Bampton, E.T.3
-
20
-
-
84896730900
-
A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3
-
Murthy A, et al. A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3. Nature. 2014;506(7489):456-462.
-
(2014)
Nature.
, vol.506
, Issue.7489
, pp. 456-462
-
-
Murthy, A.1
-
21
-
-
84861380457
-
Deubiquitinases in cancer: New functions and therapeutic options
-
Fraile JM, Quesada V, Rodriguez D, Freije JM, Lopez-Otin C. Deubiquitinases in cancer: new functions and therapeutic options. Oncogene. 2012;31(19):2373-2388.
-
(2012)
Oncogene.
, vol.31
, Issue.19
, pp. 2373-2388
-
-
Fraile, J.M.1
Quesada, V.2
Rodriguez, D.3
Freije, J.M.4
Lopez-Otin, C.5
-
22
-
-
84890178991
-
Substrate recognition in selective autophagy and the ubiquit-in-proteasome system
-
Schreiber A, Peter M. Substrate recognition in selective autophagy and the ubiquit-in-proteasome system. Biochim Biophys Acta. 2014;1843(1):163-181.
-
(2014)
Biochim Biophys Acta.
, vol.1843
, Issue.1
, pp. 163-181
-
-
Schreiber, A.1
Peter, M.2
-
23
-
-
84870980670
-
Ubiquiti-nation and selective autophagy
-
Shaid S, Brandts CH, Serve H, Dikic I. Ubiquiti-nation and selective autophagy. Cell Death Differ. 2013;20(1):21-30.
-
(2013)
Cell Death Differ.
, vol.20
, Issue.1
, pp. 21-30
-
-
Shaid, S.1
Brandts, C.H.2
Serve, H.3
Dikic, I.4
-
24
-
-
84883187967
-
Emerging roles of E3 ubiquitin ligases in autophagy
-
Kuang E, Qi J, Ronai Z. Emerging roles of E3 ubiquitin ligases in autophagy. Trends Biochem Sci. 2013;38(9):453-460.
-
(2013)
Trends Biochem Sci.
, vol.38
, Issue.9
, pp. 453-460
-
-
Kuang, E.1
Qi, J.2
Ronai, Z.3
-
25
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquiti-nated protein aggregates by autophagy
-
Pankiv S, et al. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquiti-nated protein aggregates by autophagy. J Biol Chem. 2007;282(33):24131-24145.
-
(2007)
J Biol Chem.
, vol.282
, Issue.33
, pp. 24131-24145
-
-
Pankiv, S.1
-
26
-
-
81755185877
-
α-Synuclein fate is determined by USP9X-regulated monoubiquitination
-
Rott R, et al. α-Synuclein fate is determined by USP9X-regulated monoubiquitination. Proc Natl Acad Sci U S A. 2011;108(46):18666-18671.
-
(2011)
Proc Natl Acad Sci U S A.
, vol.108
, Issue.46
, pp. 18666-18671
-
-
Rott, R.1
-
27
-
-
84920095272
-
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
-
Cornelissen T, et al. The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy. Hum Mol Genet. 2014;23(19):5227-5242.
-
(2014)
Hum Mol Genet.
, vol.23
, Issue.19
, pp. 5227-5242
-
-
Cornelissen, T.1
-
28
-
-
84903179483
-
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
-
Bingol B, et al. The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy. Nature. 2014;510(7505):370-375.
-
(2014)
Nature.
, vol.510
, Issue.7505
, pp. 370-375
-
-
Bingol, B.1
-
29
-
-
75949130828
-
PINK1/Parkin-mediated mitoph-agy is dependent on VDAC1 and p62/SQSTM1
-
Geisler S, et al. PINK1/Parkin-mediated mitoph-agy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol. 2010;12(2):119-131.
-
(2010)
Nat Cell Biol.
, vol.12
, Issue.2
, pp. 119-131
-
-
Geisler, S.1
-
30
-
-
84864060156
-
The Salmonella deubiquitinase SseL inhibits selective autoph-agy of cytosolic aggregates
-
Mesquita FS, Thomas M, Sachse M, Santos AJ, Figueira R, Holden DW. The Salmonella deubiquitinase SseL inhibits selective autoph-agy of cytosolic aggregates. PLoS Pathog. 2012;8(6):e1002743.
-
(2012)
PLoS Pathog.
, vol.8
, Issue.6
, pp. e1002743
-
-
Mesquita, F.S.1
Thomas, M.2
Sachse, M.3
Santos, A.J.4
Figueira, R.5
Holden, D.W.6
-
31
-
-
82755197676
-
Lysosomes and lysosomal cathepsins in cell death
-
Repnik U, Stoka V, Turk V, Turk B. Lysosomes and lysosomal cathepsins in cell death. Biochim Biophys Acta. 2012;1824(1):22-33.
-
(2012)
Biochim Biophys Acta.
, vol.1824
, Issue.1
, pp. 22-33
-
-
Repnik, U.1
Stoka, V.2
Turk, V.3
Turk, B.4
-
33
-
-
58149178573
-
The Degradome database: Mammalian proteases and diseases of prote-olysis
-
Database issue)
-
Quesada V, Ordonez GR, Sanchez LM, Puente XS, Lopez-Otin C. The Degradome database: mammalian proteases and diseases of prote-olysis. Nucleic Acids Res. 2009;37(Database issue):D239-D243.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. D239-D243
-
-
Quesada, V.1
Ordonez, G.R.2
Sanchez, L.M.3
Puente, X.S.4
Lopez-Otin, C.5
-
34
-
-
0034676037
-
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
-
Kirisako T, et al. The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol. 2000;151(2):263-276.
-
(2000)
J Cell Biol.
, vol.151
, Issue.2
, pp. 263-276
-
-
Kirisako, T.1
-
35
-
-
84893500894
-
Molecular mechanism of autophagic membrane-scaffold assembly and disassembly
-
Kaufmann A, Beier V, Franquelim HG, Wollert T. Molecular mechanism of autophagic membrane-scaffold assembly and disassembly. Cell. 2014;156(3):469-481.
-
(2014)
Cell.
, vol.156
, Issue.3
, pp. 469-481
-
-
Kaufmann, A.1
Beier, V.2
Franquelim, H.G.3
Wollert, T.4
-
36
-
-
34447099450
-
Atg8, a ubiquitin-like protein required for autopha-gosome formation, mediates membrane tethering and hemifusion
-
Nakatogawa H, Ichimura Y, Ohsumi Y. Atg8, a ubiquitin-like protein required for autopha-gosome formation, mediates membrane tethering and hemifusion. Cell. 2007;130(1):165-178.
-
(2007)
Cell.
, vol.130
, Issue.1
, pp. 165-178
-
-
Nakatogawa, H.1
Ichimura, Y.2
Ohsumi, Y.3
-
37
-
-
84862618804
-
A role for Atg8-PE deconjugation in autophagosome biogenesis
-
Nair U, et al. A role for Atg8-PE deconjugation in autophagosome biogenesis. Autophagy. 2012;8(5):780-793.
-
(2012)
Autophagy.
, vol.8
, Issue.5
, pp. 780-793
-
-
Nair, U.1
-
38
-
-
84857256919
-
Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis
-
Nakatogawa H, Ishii J, Asai E, Ohsumi Y. Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis. Autophagy. 2012;8(2):177-186.
-
(2012)
Autophagy.
, vol.8
, Issue.2
, pp. 177-186
-
-
Nakatogawa, H.1
Ishii, J.2
Asai, E.3
Ohsumi, Y.4
-
39
-
-
84864886799
-
Dual roles of Atg8-PE deconjugation by Atg4 in autophagy
-
Yu ZQ, et al. Dual roles of Atg8-PE deconjugation by Atg4 in autophagy. Autophagy. 2012;8(6):883-892.
-
(2012)
Autophagy.
, vol.8
, Issue.6
, pp. 883-892
-
-
Yu, Z.Q.1
-
40
-
-
84865518164
-
Differential function of the two Atg4 homologues in the aggrephagy pathway in Caenorhabditis elegans
-
Wu F, Li Y, Wang F, Noda NN, Zhang H. Differential function of the two Atg4 homologues in the aggrephagy pathway in Caenorhabditis elegans. J Biol Chem. 2012;287(35):29457-29467.
-
(2012)
J Biol Chem.
, vol.287
, Issue.35
, pp. 29457-29467
-
-
Wu, F.1
Li, Y.2
Wang, F.3
Noda, N.N.4
Zhang, H.5
-
41
-
-
14744268915
-
Processing of ATG8s, ubiquitin-like proteins, and their deconjugation by ATG4s are essential for plant autophagy
-
Yoshimoto K, et al. Processing of ATG8s, ubiquitin-like proteins, and their deconjugation by ATG4s are essential for plant autophagy. Plant Cell. 2004;16(11):2967-2983.
-
(2004)
Plant Cell.
, vol.16
, Issue.11
, pp. 2967-2983
-
-
Yoshimoto, K.1
-
42
-
-
0037423403
-
Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy
-
Marino G, Uria JA, Puente XS, Quesada V, Bord-allo J, Lopez-Otin C. Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy. J Biol Chem. 2003;278(6):3671-3678.
-
(2003)
J Biol Chem.
, vol.278
, Issue.6
, pp. 3671-3678
-
-
Marino, G.1
Uria, J.A.2
Puente, X.S.3
Quesada, V.4
Bord-Allo, J.5
Lopez-Otin, C.6
-
43
-
-
77953122645
-
LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
-
Weidberg H, Shvets E, Shpilka T, Shimron F, Shin-der V, Elazar Z. LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis. EMBO J. 2010;29(11):1792-1802.
-
(2010)
EMBO J.
, vol.29
, Issue.11
, pp. 1792-1802
-
-
Weidberg, H.1
Shvets, E.2
Shpilka, T.3
Shimron, F.4
Shin-Der, V.5
Elazar, Z.6
-
44
-
-
84869222326
-
ATG8 family proteins act as scaffolds for assembly of the ULK complex: Sequence requirements for LC3-interacting region (LIR) motifs
-
Alemu EA, et al. ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs. J Biol Chem. 2012;287(47):39275-39290.
-
(2012)
J Biol Chem.
, vol.287
, Issue.47
, pp. 39275-39290
-
-
Alemu, E.A.1
-
45
-
-
79953190772
-
Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates
-
Li M, Hou Y, Wang J, Chen X, Shao ZM, Yin XM. Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates. J Biol Chem. 2011;286(9):7327-7338.
-
(2011)
J Biol Chem.
, vol.286
, Issue.9
, pp. 7327-7338
-
-
Li, M.1
Hou, Y.2
Wang, J.3
Chen, X.4
Shao, Z.M.5
Yin, X.M.6
-
46
-
-
0347695019
-
A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L
-
Hemelaar J, Lelyveld VS, Kessler BM, Ploegh HL. A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L. J Biol Chem. 2003;278(51):51841-51850.
-
(2003)
J Biol Chem.
, vol.278
, Issue.51
, pp. 51841-51850
-
-
Hemelaar, J.1
Lelyveld, V.S.2
Kessler, B.M.3
Ploegh, H.L.4
-
47
-
-
29144517659
-
The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers
-
Kumanomidou T, et al. The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers. J Mol Biol. 2006;355(4):612-618.
-
(2006)
J Mol Biol.
, vol.355
, Issue.4
, pp. 612-618
-
-
Kumanomidou, T.1
-
48
-
-
65649136884
-
The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy
-
Satoo K, et al. The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. EMBO J. 2009;28(9):1341-1350.
-
(2009)
EMBO J.
, vol.28
, Issue.9
, pp. 1341-1350
-
-
Satoo, K.1
-
49
-
-
28844502647
-
Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy
-
Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F. Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy. J Biol Chem. 2005;280(48):40058-40065.
-
(2005)
J Biol Chem.
, vol.280
, Issue.48
, pp. 40058-40065
-
-
Sugawara, K.1
Suzuki, N.N.2
Fujioka, Y.3
Mizushima, N.4
Ohsumi, Y.5
Inagaki, F.6
-
50
-
-
84898639632
-
Atomistic autophagy: The structures of cellular self-digestion
-
Hurley JH, Schulman BA. Atomistic autophagy: the structures of cellular self-digestion. Cell. 2014;157(2):300-311.
-
(2014)
Cell.
, vol.157
, Issue.2
, pp. 300-311
-
-
Hurley, J.H.1
Schulman, B.A.2
-
51
-
-
0037515749
-
The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A
-
Scherz-Shouval R, Sagiv Y, Shorer H, Elazar Z. The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A. J Biol Chem. 2003;278(16):14053-14058.
-
(2003)
J Biol Chem.
, vol.278
, Issue.16
, pp. 14053-14058
-
-
Scherz-Shouval, R.1
Sagiv, Y.2
Shorer, H.3
Elazar, Z.4
-
52
-
-
69649090647
-
Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis
-
Betin VM, Lane JD. Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. J Cell Sci. 2009;122(pt 14):2554-2566.
-
(2009)
J Cell Sci.
, vol.122
, pp. 2554-2566
-
-
Betin, V.M.1
Lane, J.D.2
-
53
-
-
84862280415
-
A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochon-drial import and oxidative stress
-
Betin VM, MacVicar TD, Parsons SF, Anstee DJ, Lane JD. A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochon-drial import and oxidative stress. Autophagy. 2012;8(4):664-676.
-
(2012)
Autophagy.
, vol.8
, Issue.4
, pp. 664-676
-
-
Betin, V.M.1
MacVicar, T.D.2
Parsons, S.F.3
Anstee, D.J.4
Lane, J.D.5
-
54
-
-
84880913038
-
Autophagy facilitates organelle clearance during differentiation of human ery-throblasts: Evidence for a role for ATG4 paralogs during autophagosome maturation
-
Betin VM, Singleton BK, Parsons SF, Anstee DJ, Lane JD. Autophagy facilitates organelle clearance during differentiation of human ery-throblasts: evidence for a role for ATG4 paralogs during autophagosome maturation. Autophagy. 2013;9(6):881-893.
-
(2013)
Autophagy.
, vol.9
, Issue.6
, pp. 881-893
-
-
Betin, V.M.1
Singleton, B.K.2
Parsons, S.F.3
Anstee, D.J.4
Lane, J.D.5
-
55
-
-
79251577061
-
The regulation of autophagy - Unanswered questions
-
Chen Y, Klionsky DJ. The regulation of autophagy - unanswered questions. J Cell Sci. 2011; 124(pt 2):161-170.
-
(2011)
J Cell Sci.
, vol.124
, pp. 161-170
-
-
Chen, Y.1
Klionsky, D.J.2
-
57
-
-
84877311822
-
Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses
-
Kenzelmann Broz D, et al. Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses. Genes Dev. 2013;27(9):1016-1031.
-
(2013)
Genes Dev.
, vol.27
, Issue.9
, pp. 1016-1031
-
-
Kenzelmann Broz, D.1
-
58
-
-
36448940798
-
FoxO3 controls autoph-agy in skeletal muscle in vivo
-
Mammucari C, et al. FoxO3 controls autoph-agy in skeletal muscle in vivo. Cell Metab. 2007;6(6):458-471.
-
(2007)
Cell Metab.
, vol.6
, Issue.6
, pp. 458-471
-
-
Mammucari, C.1
-
59
-
-
36448968532
-
FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells
-
Zhao J, et al. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab. 2007;6(6):472-483.
-
(2007)
Cell Metab.
, vol.6
, Issue.6
, pp. 472-483
-
-
Zhao, J.1
-
60
-
-
57449121645
-
The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells
-
Lu Z, et al. The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells. J Clin Invest. 2008;118(12):3917-3929.
-
(2008)
J Clin Invest.
, vol.118
, Issue.12
, pp. 3917-3929
-
-
Lu, Z.1
-
61
-
-
84905053713
-
ARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7
-
Lu Z, et al. ARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7. Cell Death Differ. 2014;21(8):1275-1289.
-
(2014)
Cell Death Differ.
, vol.21
, Issue.8
, pp. 1275-1289
-
-
Lu, Z.1
-
62
-
-
53749087325
-
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
-
Chen ZH, et al. Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One. 2008;3(10):e3316.
-
(2008)
PLoS One.
, vol.3
, Issue.10
, pp. e3316
-
-
Chen, Z.H.1
-
63
-
-
84881299126
-
Transactivation of Atg4b by C/EBPβ promotes autophagy to facilitate adipogenesis
-
Guo L, et al. Transactivation of Atg4b by C/EBPβ promotes autophagy to facilitate adipogenesis. Mol Cell Biol. 2013;33(16):3180-3190.
-
(2013)
Mol Cell Biol.
, vol.33
, Issue.16
, pp. 3180-3190
-
-
Guo, L.1
-
64
-
-
81255143302
-
MicroRNA-101 is a potent inhibitor of autophagy
-
Frankel LB, et al. microRNA-101 is a potent inhibitor of autophagy. EMBO J. 2011;30(22):4628-4641.
-
(2011)
EMBO J.
, vol.30
, Issue.22
, pp. 4628-4641
-
-
Frankel, L.B.1
-
65
-
-
85046981182
-
MiR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1
-
Korkmaz G, le Sage C, Tekirdag KA, Agami R, Gozuacik D. miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1. Autophagy. 2012;8(2):165-176.
-
(2012)
Autophagy.
, vol.8
, Issue.2
, pp. 165-176
-
-
Korkmaz, G.1
Le Sage, C.2
Tekirdag, K.A.3
Agami, R.4
Gozuacik, D.5
-
66
-
-
84902184873
-
The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells
-
Rothe K, et al. The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells. Blood. 2014;123(23):3622-3634.
-
(2014)
Blood.
, vol.123
, Issue.23
, pp. 3622-3634
-
-
Rothe, K.1
-
67
-
-
34247186472
-
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
-
Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J. 2007;26(7):1749-1760.
-
(2007)
EMBO J.
, vol.26
, Issue.7
, pp. 1749-1760
-
-
Scherz-Shouval, R.1
Shvets, E.2
Fass, E.3
Shorer, H.4
Gil, L.5
Elazar, Z.6
-
68
-
-
73649087254
-
Constitutive reactive oxygen species generation from autophagosome/lys-osome in neuronal oxidative toxicity
-
Kubota C, et al. Constitutive reactive oxygen species generation from autophagosome/lys-osome in neuronal oxidative toxicity. J Biol Chem. 2010;285(1):667-674.
-
(2010)
J Biol Chem.
, vol.285
, Issue.1
, pp. 667-674
-
-
Kubota, C.1
-
69
-
-
84880616033
-
7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B
-
He C, et al. 7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B. Am J Pathol. 2013;183(2):626-637.
-
(2013)
Am J Pathol.
, vol.183
, Issue.2
, pp. 626-637
-
-
He, C.1
-
70
-
-
84868148976
-
Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection
-
Kuang E, et al. Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection. PLoS Genet. 2012;8(10):e1003007.
-
(2012)
PLoS Genet.
, vol.8
, Issue.10
, pp. e1003007
-
-
Kuang, E.1
-
71
-
-
77951215334
-
Roles of the lipid-binding motifs of Atg18 and Atg21 in the cytoplasm to vacuole targeting pathway and autophagy
-
Nair U, Cao Y, Xie Z, Klionsky DJ. Roles of the lipid-binding motifs of Atg18 and Atg21 in the cytoplasm to vacuole targeting pathway and autophagy. J Biol Chem. 2010;285(15):11476-11488.
-
(2010)
J Biol Chem.
, vol.285
, Issue.15
, pp. 11476-11488
-
-
Nair, U.1
Cao, Y.2
Xie, Z.3
Klionsky, D.J.4
-
72
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma A, et al. The role of autophagy during the early neonatal starvation period. Nature. 2004;432(7020):1032-1036.
-
(2004)
Nature.
, vol.432
, Issue.7020
, pp. 1032-1036
-
-
Kuma, A.1
-
73
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-defi-cient mice
-
Komatsu M, et al. Impairment of starvation-induced and constitutive autophagy in Atg7-defi-cient mice. J Cell Biol. 2005;169(3):425-434.
-
(2005)
J Cell Biol.
, vol.169
, Issue.3
, pp. 425-434
-
-
Komatsu, M.1
-
74
-
-
34547132328
-
Tissue-specific autophagy alterations and increased tumorigene-sis in mice deficient in Atg4C/autophagin-3
-
Marino G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N, Lopez-Otin C. Tissue-specific autophagy alterations and increased tumorigene-sis in mice deficient in Atg4C/autophagin-3. J Biol Chem. 2007;282(25):18573-18583.
-
(2007)
J Biol Chem.
, vol.282
, Issue.25
, pp. 18573-18583
-
-
Marino, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
Lopez-Otin, C.6
-
75
-
-
77954988580
-
Autophagy is essential for mouse sense of balance
-
Marino G, et al. Autophagy is essential for mouse sense of balance. J Clin Invest. 2010;120(7):2331-2344.
-
(2010)
J Clin Invest.
, vol.120
, Issue.7
, pp. 2331-2344
-
-
Marino, G.1
-
76
-
-
77957653753
-
Autophagy, proteases and the sense of balance
-
Cabrera S, Marino G, Fernandez AF, Lopez-Otin C. Autophagy, proteases and the sense of balance. Autophagy. 2010;6(7):961-963.
-
(2010)
Autophagy.
, vol.6
, Issue.7
, pp. 961-963
-
-
Cabrera, S.1
Marino, G.2
Fernandez, A.F.3
Lopez-Otin, C.4
-
77
-
-
84882942176
-
ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
-
Cabrera S, et al. ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis. Autophagy. 2013;9(8):1188-1200.
-
(2013)
Autophagy.
, vol.9
, Issue.8
, pp. 1188-1200
-
-
Cabrera, S.1
-
78
-
-
83455173649
-
Autophagy proteins regulate the secretory component of osteoclastic bone resorption
-
DeSelm CJ, et al. Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev Cell. 2011;21(5):966-974.
-
(2011)
Dev Cell.
, vol.21
, Issue.5
, pp. 966-974
-
-
Deselm, C.J.1
-
79
-
-
77954992496
-
A balancing act for auto-phagin
-
Till A, Subramani S. A balancing act for auto-phagin. J Clin Invest. 2010;120(7):2273-2276.
-
(2010)
J Clin Invest.
, vol.120
, Issue.7
, pp. 2273-2276
-
-
Till, A.1
Subramani, S.2
-
80
-
-
84873407151
-
Non-autophagic roles of autophagy-related proteins
-
Subramani S, Malhotra V. Non-autophagic roles of autophagy-related proteins. EMBO Rep. 2013;14(2):143-151.
-
(2013)
EMBO Rep.
, vol.14
, Issue.2
, pp. 143-151
-
-
Subramani, S.1
Malhotra, V.2
-
81
-
-
84859982621
-
Nondegradative role of Atg5-Atg12/Atg16L1 autophagy protein complex in antiviral activity of interferon γ
-
Hwang S, et al. Nondegradative role of Atg5-Atg12/Atg16L1 autophagy protein complex in antiviral activity of interferon γ. Cell Host Microbe. 2012;11(4):397-409.
-
(2012)
Cell Host Microbe.
, vol.11
, Issue.4
, pp. 397-409
-
-
Hwang, S.1
-
82
-
-
84880376355
-
Emerging regulation and functions of autophagy
-
Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nat Cell Biol. 2013;15(7):713-720.
-
(2013)
Nat Cell Biol.
, vol.15
, Issue.7
, pp. 713-720
-
-
Boya, P.1
Reggiori, F.2
Codogno, P.3
-
83
-
-
84901641301
-
Defective autophagy impairs ATF3 activity and worsens lung injury during endotox-emia
-
Aguirre A, et al. Defective autophagy impairs ATF3 activity and worsens lung injury during endotox-emia. J Mol Med (Berl). 2014;92(6):665-676.
-
(2014)
J Mol Med (Berl).
, vol.92
, Issue.6
, pp. 665-676
-
-
Aguirre, A.1
-
84
-
-
84879177668
-
Impairment of autophagy decreases ventilator-induced lung injury by blockade of the NF-κB pathway
-
Lopez-Alonso I, et al. Impairment of autophagy decreases ventilator-induced lung injury by blockade of the NF-κB pathway. Am J Physiol Lung Cell Mol Physiol. 2013;304(12):L844-L852.
-
(2013)
Am J Physiol Lung Cell Mol Physiol.
, vol.304
, Issue.12
, pp. L844-L852
-
-
Lopez-Alonso, I.1
-
85
-
-
84907059940
-
Hypomethylation signature of tumor-initiating cells predicts poor prognosis of ovarian cancer patients
-
Liao YP, et al. Hypomethylation signature of tumor-initiating cells predicts poor prognosis of ovarian cancer patients. Hum Mol Genet. 2014;23(7):1894-1906.
-
(2014)
Hum Mol Genet.
, vol.23
, Issue.7
, pp. 1894-1906
-
-
Liao, Y.P.1
-
86
-
-
84887341385
-
A mammosphere formation RNAi screen reveals that ATG4A promotes a breast cancer stem-like phenotype
-
Wolf J, et al. A mammosphere formation RNAi screen reveals that ATG4A promotes a breast cancer stem-like phenotype. Breast Cancer Res. 2013;15(6):R109.
-
(2013)
Breast Cancer Res.
, vol.15
, Issue.6
, pp. R109
-
-
Wolf, J.1
-
87
-
-
77957596324
-
A pilot study on morphology and the mechanism involved in linearly patterned programmed cell necrosis in melanoma
-
Han C, et al. A pilot study on morphology and the mechanism involved in linearly patterned programmed cell necrosis in melanoma. Oncol Lett. 2010;1(5):821-826.
-
(2010)
Oncol Lett.
, vol.1
, Issue.5
, pp. 821-826
-
-
Han, C.1
-
88
-
-
84861526009
-
Deconvoluting the context-dependent role for autophagy in cancer
-
White E. Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer. 2012;12(6):401-410.
-
(2012)
Nat Rev Cancer.
, vol.12
, Issue.6
, pp. 401-410
-
-
White, E.1
-
89
-
-
84855959618
-
Genetic variants in autophagy-re-lated genes and granuloma formation in a cohort of surgically treated Crohn's disease patients
-
Brinar M, et al. Genetic variants in autophagy-re-lated genes and granuloma formation in a cohort of surgically treated Crohn's disease patients. J Crohns Colitis. 2012;6(1):43-50.
-
(2012)
J Crohns Colitis.
, vol.6
, Issue.1
, pp. 43-50
-
-
Brinar, M.1
-
90
-
-
44349124113
-
The genetics and immunopathogenesis of inflammatory bowel disease
-
Cho JH. The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol. 2008;8(6):458-466.
-
(2008)
Nat Rev Immunol.
, vol.8
, Issue.6
, pp. 458-466
-
-
Cho, J.H.1
-
91
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet. 2007;39(2):207-211.
-
(2007)
Nat Genet.
, vol.39
, Issue.2
, pp. 207-211
-
-
Hampe, J.1
-
92
-
-
79955790354
-
Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease
-
Henckaerts L, et al. Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease. Inflamm Bowel Dis. 2011;17(6):1392-1397.
-
(2011)
Inflamm Bowel Dis.
, vol.17
, Issue.6
, pp. 1392-1397
-
-
Henckaerts, L.1
-
93
-
-
34347338690
-
Sequence variants in the autoph-agy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
Parkes M, et al. Sequence variants in the autoph-agy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet. 2007;39(7):830-832.
-
(2007)
Nat Genet.
, vol.39
, Issue.7
, pp. 830-832
-
-
Parkes, M.1
-
94
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease patho-genesis
-
Rioux JD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease patho-genesis. Nat Genet. 2007;39(5):596-604.
-
(2007)
Nat Genet.
, vol.39
, Issue.5
, pp. 596-604
-
-
Rioux, J.D.1
-
95
-
-
84859958624
-
HIV-1 and HIV-2 infections induce autophagy in Jurkat and CD4+ T cells
-
Wang X, et al. HIV-1 and HIV-2 infections induce autophagy in Jurkat and CD4+ T cells. Cell Signal. 2012;24(7):1414-1419.
-
(2012)
Cell Signal.
, vol.24
, Issue.7
, pp. 1414-1419
-
-
Wang, X.1
-
96
-
-
69549135689
-
The autophagy machinery is required to initiate hepatitis C virus replication
-
Dreux M, Gastaminza P, Wieland SF, Chisari FV. The autophagy machinery is required to initiate hepatitis C virus replication. Proc Natl Acad Sci U S A. 2009;106(33):14046-14051.
-
(2009)
Proc Natl Acad Sci U S A.
, vol.106
, Issue.33
, pp. 14046-14051
-
-
Dreux, M.1
Gastaminza, P.2
Wieland, S.F.3
Chisari, F.V.4
-
97
-
-
79551573171
-
Autophagy in protists
-
Duszenko M, et al. Autophagy in protists. Au tophagy. 2011;7(2):127-158.
-
(2011)
Au Tophagy.
, vol.7
, Issue.2
, pp. 127-158
-
-
Duszenko, M.1
-
98
-
-
82755198904
-
The peptidases of Trypanosoma cruzi: Digestive enzymes, virulence factors, and mediators of autophagy and programmed cell death
-
Alvarez VE, Niemirowicz GT, Cazzulo JJ. The peptidases of Trypanosoma cruzi: digestive enzymes, virulence factors, and mediators of autophagy and programmed cell death. Biochim Biophys Acta. 2012;1824(1):195-206.
-
(2012)
Biochim Biophys Acta.
, vol.1824
, Issue.1
, pp. 195-206
-
-
Alvarez, V.E.1
Niemirowicz, G.T.2
Cazzulo, J.J.3
-
99
-
-
84873295136
-
Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of Leishma-nia major
-
Williams RA, Mottram JC, Coombs GH. Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of Leishma-nia major. J Biol Chem. 2013;288(5):3678-3690.
-
(2013)
J Biol Chem.
, vol.288
, Issue.5
, pp. 3678-3690
-
-
Williams, R.A.1
Mottram, J.C.2
Coombs, G.H.3
-
100
-
-
41249091247
-
Autophagy is involved in nutritional stress response and differentiation in Trypano-soma cruzi
-
Alvarez VE, Kosec G, Sant'Anna C, Turk V, Cazzulo JJ, Turk B. Autophagy is involved in nutritional stress response and differentiation in Trypano-soma cruzi. J Biol Chem. 2008;283(6):3454-3464.
-
(2008)
J Biol Chem.
, vol.283
, Issue.6
, pp. 3454-3464
-
-
Alvarez, V.E.1
Kosec, G.2
Sant'Anna, C.3
Turk, V.4
Cazzulo, J.J.5
Turk, B.6
-
101
-
-
84880260000
-
Meta-caspases, autophagins and metallocarboxypep-tidases: Potential new targets for chemotherapy of the trypanosomiases
-
Alvarez VE, Niemirowicz GT, Cazzulo JJ. Meta-caspases, autophagins and metallocarboxypep-tidases: potential new targets for chemotherapy of the trypanosomiases. Curr Med Chem. 2013;20(25):3069-3077.
-
(2013)
Curr Med Chem.
, vol.20
, Issue.25
, pp. 3069-3077
-
-
Alvarez, V.E.1
Niemirowicz, G.T.2
Cazzulo, J.J.3
-
102
-
-
84878864199
-
The hallmarks of aging
-
Lopez-Otin C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013;153(6):1194-1217.
-
(2013)
Cell.
, vol.153
, Issue.6
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
103
-
-
46249086799
-
Premature aging in mice activates a systemic metabolic response involving autophagy induction
-
Marino G, et al. Premature aging in mice activates a systemic metabolic response involving autophagy induction. Hum Mol Genet. 2008;17(14):2196-2211.
-
(2008)
Hum Mol Genet.
, vol.17
, Issue.14
, pp. 2196-2211
-
-
Marino, G.1
-
104
-
-
80052641742
-
A genome-wide association study of aging
-
Walter S, et al. A genome-wide association study of aging. Neurobiol Aging. 2011; 32(11):2109.e15-2109.e28.
-
(2011)
Neurobiol Aging.
, vol.32
, Issue.11
, pp. 2109e15-2109e28
-
-
Walter, S.1
-
105
-
-
80052388263
-
A monitoring method for Atg4 activation in living cells using peptide-con-jugated polymeric nanoparticles
-
Choi KM, et al. A monitoring method for Atg4 activation in living cells using peptide-con-jugated polymeric nanoparticles. Autophagy. 2011;7(9):1052-1062.
-
(2011)
Autophagy.
, vol.7
, Issue.9
, pp. 1052-1062
-
-
Choi, K.M.1
-
106
-
-
77957656800
-
Synthetic substrates for measuring activity of autophagy proteases: Autophagins (Atg4)
-
Shu CW, Drag M, Bekes M, Zhai D, Salvesen GS, Reed JC. Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4). Autophagy. 2010;6(7):936-947.
-
(2010)
Autophagy.
, vol.6
, Issue.7
, pp. 936-947
-
-
Shu, C.W.1
Drag, M.2
Bekes, M.3
Zhai, D.4
Salvesen, G.S.5
Reed, J.C.6
-
107
-
-
79951968329
-
High-throughput fluorescence assay for small-molecule inhibitors of autopha-gins/Atg4
-
Shu CW, et al. High-throughput fluorescence assay for small-molecule inhibitors of autopha-gins/Atg4. J Biomol Screen. 2011;16(2):174-182.
-
(2011)
J Biomol Screen.
, vol.16
, Issue.2
, pp. 174-182
-
-
Shu, C.W.1
-
108
-
-
84898908105
-
Development of fluorescent substrates and assays for the key autophagy-related cysteine protease enzyme, ATG4B
-
Nguyen TG, et al. Development of fluorescent substrates and assays for the key autophagy-related cysteine protease enzyme, ATG4B. Assay Drug Dev Technol. 2014;12(3):176-189.
-
(2014)
Assay Drug Dev Technol.
, vol.12
, Issue.3
, pp. 176-189
-
-
Nguyen, T.G.1
-
109
-
-
84896542255
-
Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis
-
Dupont N, et al. Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis. Curr Biol. 2014;24(6):609-620.
-
(2014)
Curr Biol.
, vol.24
, Issue.6
, pp. 609-620
-
-
Dupont, N.1
-
110
-
-
58149290220
-
An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure
-
Fujita N, et al. An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure. Mol Biol Cell. 2008;19(11):4651-4659.
-
(2008)
Mol Biol Cell.
, vol.19
, Issue.11
, pp. 4651-4659
-
-
Fujita, N.1
-
111
-
-
84886883442
-
Glucose-starved cells do not engage in prosurvival autophagy
-
Ramirez-Peinado S, et al. Glucose-starved cells do not engage in prosurvival autophagy. J Biol Chem. 2013;288(42):30387-30398.
-
(2013)
J Biol Chem.
, vol.288
, Issue.42
, pp. 30387-30398
-
-
Ramirez-Peinado, S.1
-
112
-
-
84901405852
-
Autophagy enhances hepato-cellular carcinoma progression by activation of mitochondrial beta-oxidation
-
Toshima T, et al. Autophagy enhances hepato-cellular carcinoma progression by activation of mitochondrial beta-oxidation. J Gastroenterol. 2014;49(5):907-916.
-
(2014)
J Gastroenterol.
, vol.49
, Issue.5
, pp. 907-916
-
-
Toshima, T.1
-
113
-
-
84876211114
-
MiR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells
-
Xu Y, et al. miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells. Oncol Rep. 2013;29(5):2019-2024.
-
(2013)
Oncol Rep.
, vol.29
, Issue.5
, pp. 2019-2024
-
-
Xu, Y.1
-
114
-
-
84863344601
-
Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation
-
Huang Y, Guerrero-Preston R, Ratovitski EA. Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation. Cell Cycle. 2012;11(6):1247-1259.
-
(2012)
Cell Cycle.
, vol.11
, Issue.6
, pp. 1247-1259
-
-
Huang, Y.1
Guerrero-Preston, R.2
Ratovitski, E.A.3
-
115
-
-
84864313580
-
Autoph-agy in the brains of young patients with poorly controlled T1DM and fatal diabetic ketoacidosis
-
Hoffman WH, Shacka JJ, Andjelkovic AV. Autoph-agy in the brains of young patients with poorly controlled T1DM and fatal diabetic ketoacidosis. Exp Mol Pathol. 2012;93(2):273-280.
-
(2012)
Exp Mol Pathol.
, vol.93
, Issue.2
, pp. 273-280
-
-
Hoffman, W.H.1
Shacka, J.J.2
Andjelkovic, A.V.3
-
116
-
-
84864118315
-
JNK-dependent Atg4 upregulation mediates asperphenamate derivative BBP-in-duced autophagy in MCF-7 cells
-
Li Y, et al. JNK-dependent Atg4 upregulation mediates asperphenamate derivative BBP-in-duced autophagy in MCF-7 cells. Toxicol Appl Pharmacol. 2012;263(1):21-31.
-
(2012)
Toxicol Appl Pharmacol.
, vol.263
, Issue.1
, pp. 21-31
-
-
Li, Y.1
-
117
-
-
84894031635
-
Autophagy gene fingerprint in human ischemia and reperfusion
-
Singh KK, et al. Autophagy gene fingerprint in human ischemia and reperfusion. J Thorac Cardiovasc Surg. 2014;147(3):1065-1072.e1061.
-
(2014)
J Thorac Cardiovasc Surg.
, vol.147
, Issue.3
, pp. 1065-1072e1061
-
-
Singh, K.K.1
-
118
-
-
81855221944
-
Autophagy suppresses age-dependent ischemia and reperfusion injury in livers of mice
-
Wang JH, et al. Autophagy suppresses age-dependent ischemia and reperfusion injury in livers of mice. Gastroenterology. 2011;141(6):2188-2199.e2186.
-
(2011)
Gastroenterology.
, vol.141
, Issue.6
, pp. 2188-2199e2186
-
-
Wang, J.H.1
-
119
-
-
84879942257
-
Atg4b-dependent autophagic flux alleviates Huntington's disease progression
-
Proenca CC, et al. Atg4b-dependent autophagic flux alleviates Huntington's disease progression. PLoS O ne. 2013;8(7):e68357.
-
(2013)
PLoS O Ne.
, vol.8
, Issue.7
, pp. e68357
-
-
Proenca, C.C.1
-
120
-
-
84888820115
-
Context-dependent role of ATG4B as target for autophagy inhibition in prostate cancer therapy
-
Tran E, et al. Context-dependent role of ATG4B as target for autophagy inhibition in prostate cancer therapy. Biochem Biophys Res Commun. 2013;441(4):726-731.
-
(2013)
Biochem Biophys Res Commun.
, vol.441
, Issue.4
, pp. 726-731
-
-
Tran, E.1
-
121
-
-
40449086885
-
Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy
-
Apel A, Herr I, Schwarz H, Rodemann HP, Mayer A. Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res. 2008;68(5):1485-1494.
-
(2008)
Cancer Res.
, vol.68
, Issue.5
, pp. 1485-1494
-
-
Apel, A.1
Herr, I.2
Schwarz, H.3
Rodemann, H.P.4
Mayer, A.5
-
122
-
-
84866057244
-
Targeting autoph-agy: The Achilles' heel of cancer
-
Gorski SM, Ries J, Lum JJ. Targeting autoph-agy: the Achilles' heel of cancer. Autophagy. 2012;8(8):1279-1280.
-
(2012)
Autophagy.
, vol.8
, Issue.8
, pp. 1279-1280
-
-
Gorski, S.M.1
Ries, J.2
Lum, J.J.3
-
123
-
-
33748308883
-
Targeting proteases: Successes, failures and future prospects
-
Turk B. Targeting proteases: successes, failures and future prospects. Nat Rev Drug Discov. 2006;5(9):785-799.
-
(2006)
Nat Rev Drug Discov.
, vol.5
, Issue.9
, pp. 785-799
-
-
Turk, B.1
-
124
-
-
0001417555
-
GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28
-
Sagiv Y, Legesse-Miller A, Porat A, Elazar Z. GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28. EMBO J. 2000;19(7):1494-1504.
-
(2000)
EMBO J.
, vol.19
, Issue.7
, pp. 1494-1504
-
-
Sagiv, Y.1
Legesse-Miller, A.2
Porat, A.3
Elazar, Z.4
-
125
-
-
0034919997
-
The subcellular distribution of GABARAP and its ability to interact with NSF suggest a role for this protein in the intracellular transport of GABA(A) receptors
-
Kittler JT, et al. The subcellular distribution of GABARAP and its ability to interact with NSF suggest a role for this protein in the intracellular transport of GABA(A) receptors. Mol Cell Neuro-sci. 2001;18(1):13-25.
-
(2001)
Mol Cell Neuro-sci.
, vol.18
, Issue.1
, pp. 13-25
-
-
Kittler, J.T.1
-
126
-
-
33646372722
-
GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor
-
Chen C, Li JG, Chen Y, Huang P, Wang Y, Liu-Chen LY. GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor. J Biol Chem. 2006;281(12):7983-7993.
-
(2006)
J Biol Chem.
, vol.281
, Issue.12
, pp. 7983-7993
-
-
Chen, C.1
Li, J.G.2
Chen, Y.3
Huang, P.4
Wang, Y.5
Liu-Chen, L.Y.6
-
127
-
-
0023156677
-
18 kDa microtu-bule-associated protein: Identification as a new light chain (LC-3) of microtubule-associated protein 1 (MAP-1)
-
Kuznetsov SA, Gelfand VI. 18 kDa microtu-bule-associated protein: identification as a new light chain (LC-3) of microtubule-associated protein 1 (MAP-1). FEBS Lett. 1987;212(1):145-148.
-
(1987)
FEBS Lett.
, vol.212
, Issue.1
, pp. 145-148
-
-
Kuznetsov, S.A.1
Gelfand, V.I.2
-
128
-
-
0028289946
-
Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B
-
Mann SS, Hammarback JA. Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B. J Biol Chem. 1994;269(15):11492-11497.
-
(1994)
J Biol Chem.
, vol.269
, Issue.15
, pp. 11492-11497
-
-
Mann, S.S.1
Hammarback, J.A.2
-
129
-
-
84856010816
-
Selective subversion of autoph-agy complexes facilitates completion of the Brucella intracellular cycle
-
Starr T, et al. Selective subversion of autoph-agy complexes facilitates completion of the Brucella intracellular cycle. Cell Host Microbe. 2012;11(1):33-45.
-
(2012)
Cell Host Microbe.
, vol.11
, Issue.1
, pp. 33-45
-
-
Starr, T.1
-
130
-
-
84856760438
-
Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice
-
Rodriguez-Muela N, Germain F, Marino G, Fitze PS, Boya P. Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice. Cell Death Differ. 2012;19(1):162-169.
-
(2012)
Cell Death Differ.
, vol.19
, Issue.1
, pp. 162-169
-
-
Rodriguez-Muela, N.1
Germain, F.2
Marino, G.3
Fitze, P.S.4
Boya, P.5
-
131
-
-
78149475088
-
Regulation of mammalian autophagy in physiology and pathophysiology
-
Ravikumar B, et al. Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev. 2010;90(4):1383-1435.
-
(2010)
Physiol Rev.
, vol.90
, Issue.4
, pp. 1383-1435
-
-
Ravikumar, B.1
-
132
-
-
84874596968
-
Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection
-
Byrne BG, Dubuisson JF, Joshi AD, Persson JJ, Swanson MS. Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection. MBio. 2013;4(1):e00620-12.
-
(2013)
MBio.
, vol.4
, Issue.1
, pp. e00620-e00712
-
-
Byrne, B.G.1
Dubuisson, J.F.2
Joshi, A.D.3
Persson, J.J.4
Swanson, M.S.5
-
133
-
-
84866002291
-
The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
-
Cerami E, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2012;2(5):401-404.
-
(2012)
Cancer Discov.
, vol.2
, Issue.5
, pp. 401-404
-
-
Cerami, E.1
-
134
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao J, et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal. 2013;6(269):pl1.
-
(2013)
Sci Signal.
, vol.6
, Issue.269
, pp. 11
-
-
Gao, J.1
|