Development of fluorescent substrates and assays for the key autophagy-related cysteine protease enzyme, ATG4B

Assay and Drug Development Technologies

Volumn 12, Issue 3, 2014, Pages 176-189

  Nguyen, Thanh G ^a   Honson, Nicolette S ^b   Arns, Steven ^a   Davis, Tara L ^c   Dhe Paganon, Sirano ^c   Kovacic, Suzana ^a   Kumar, Nag S ^a   Pfeifer, Tom A ^b   Young, Robert N ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b Center for Drug Research and Development   (Canada)

^c Structural Genomics Consortium   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATG4B PROTEIN; CYSTEINE PROTEINASE; PHOSPHOLIPASE A2; PROTEIN; SUBSTRATE PROTEIN LC3 B; UNCLASSIFIED DRUG; ATG4B PROTEIN, HUMAN; FLUORESCENT DYE;

ARTICLE; AUTOPHAGY; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SUBSTRATE; FLUORESCENCE ANALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; MASS SPECTROMETRY; MOLECULAR LIBRARY; PROTEIN CLEAVAGE; QUANTITATIVE ANALYSIS; SIGNAL NOISE RATIO; CHEMISTRY; DRUG SCREENING; ENZYME ACTIVATION; ENZYME SPECIFICITY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; PROCEDURES;

CYSTEINE ENDOPEPTIDASES; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENT DYES; MASS SPECTROMETRY; SUBSTRATE SPECIFICITY;

EID: 84898908105     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/adt.2013.561     Document Type: Article

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