Atg4b-Dependent Autophagic Flux Alleviates Huntington's Disease Progression

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Proenca, Catia C ^a   Stoehr, Natacha ^a   Bernhard, Mario ^a   Seger, Shanon ^a,e   Genoud, Christel ^b   Roscic, Ana ^a   Paganetti, Paolo ^a,d   Liu, Shanming ^a   Murphy, Leon O ^a   Kuhn, Rainer ^a,c   Bouwmeester, Tewis ^a   Galimberti, Ivan ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^c IRBM Promidis Pomezia   (Italy)

^d AC IMMUNE SA   (Switzerland)

^e Actelion Pharmaceuticals Allschwil   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 4B; AZD 8055; HUNTINGTIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BRAIN CORTEX; BRAIN SLICE; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE COURSE; DRUG EFFECT; DRUG TARGETING; EMBRYO; HUNTINGTON CHOREA; IN VITRO STUDY; MOUSE; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NONHUMAN; PROTEIN AGGREGATION;

ANIMALS; AUTOPHAGY; BIOCATALYSIS; CEREBRAL CORTEX; CYSTEINE ENDOPEPTIDASES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HUNTINGTON DISEASE; MORPHOLINES; NEOSTRIATUM; NERVE DEGENERATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; PHENOTYPE; TOR SERINE-THREONINE KINASES;

MUS MUSCULUS;

EID: 84879942257     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068357     Document Type: Article

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