메뉴 건너뛰기




Volumn 5, Issue DEC, 2014, Pages

Cooperation between HMGA1, PDX-1 and MafA is essential for glucose-induced insulin transcription in pancreatic beta cells

Author keywords

Diabetes; HMGA1; Insulin gene; MafA; PDX 1; Transcription; cells

Indexed keywords

GLUCOSE; GLUTATHIONE TRANSFERASE; HIGH MOBILITY GROUP AT HOOK 1 PROTEIN; INSULIN RECEPTOR; PEPTIDES AND PROTEINS; PROTEIN V MAF; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

EID: 84920122824     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2014.00237     Document Type: Review
Times cited : (44)

References (60)
  • 1
    • 84907274301 scopus 로고    scopus 로고
    • Recent advances in the molecular genetics of type 2 diabetes mellitus
    • Brunetti A, Chiefar E, Foti D. Recent advances in the molecular genetics of type 2 diabetes mellitus. World J Diabetes (2014) 5(2):128-40
    • (2014) World J Diabetes , vol.5 , Issue.2 , pp. 128-140
    • Brunetti, A.1    Chiefar, E.2    Foti, D.3
  • 2
    • 84855679374 scopus 로고    scopus 로고
    • Perspectives on the contribution of genetics to the pathogenesis of type 2 diabetes mellitus
    • Brunetti A, Chiefari E, Foti D. Perspectives on the contribution of genetics to the pathogenesis of type 2 diabetes mellitus. Recenti Prog Med (2011) 102(12):468-75
    • (2011) Recenti Prog Med , vol.102 , Issue.12 , pp. 468-475
    • Brunetti, A.1    Chiefari, E.2    Foti, D.3
  • 3
    • 84875966088 scopus 로고    scopus 로고
    • Regulation of insulin synthesis and secretion and pancreatic beta-cell dysfunction in diabetes
    • Fu Z, Gilbert ER, Liu D. Regulation of insulin synthesis and secretion and pancreatic beta-cell dysfunction in diabetes. Curr Diabetes Rev (2013) 9(1):25-53
    • (2013) Curr Diabetes Rev , vol.9 , Issue.1 , pp. 25-53
    • Fu, Z.1    Gilbert, E.R.2    Liu, D.3
  • 4
    • 33846459471 scopus 로고    scopus 로고
    • Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells
    • Vander Mierde D, Scheuner D, Quintens R, Patel R, Song B, Tsukamoto K, et al. Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells. Endocrinology (2007) 148(2):609-17
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 609-617
    • Vander Mierde, D.1    Scheuner, D.2    Quintens, R.3    Patel, R.4    Song, B.5    Tsukamoto, K.6
  • 5
    • 0028127761 scopus 로고
    • Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression
    • Sharma A, Stein R. Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression. Mol Cell Biol (1994) 14(2):871-9
    • (1994) Mol Cell Biol , vol.14 , Issue.2 , pp. 871-879
    • Sharma, A.1    Stein, R.2
  • 7
    • 33845544522 scopus 로고    scopus 로고
    • Comparative analysis of insulin gene promoters: implications for diabetes research
    • Hay CW, Docherty K. Comparative analysis of insulin gene promoters: implications for diabetes research. Diabetes (2006) 55(12):3201-13
    • (2006) Diabetes , vol.55 , Issue.12 , pp. 3201-3213
    • Hay, C.W.1    Docherty, K.2
  • 8
    • 0021071029 scopus 로고
    • Cell-specific expression controlled by the 5'-flanking region of insulin and chymotrypsin genes
    • Walker MD, Edlund T, Boulet AM, Rutter WJ. Cell-specific expression controlled by the 5'-flanking region of insulin and chymotrypsin genes. Nature (1983) 306(5943):557-61
    • (1983) Nature , vol.306 , Issue.5943 , pp. 557-561
    • Walker, M.D.1    Edlund, T.2    Boulet, A.M.3    Rutter, W.J.4
  • 9
    • 0027154077 scopus 로고
    • Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters
    • Melloul D, Ben-Neriah Y, Cerasi E. Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters. Proc Natl Acad Sci USA (1993) 90(9):3865-9
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.9 , pp. 3865-3869
    • Melloul, D.1    Ben-Neriah, Y.2    Cerasi, E.3
  • 10
    • 0036210550 scopus 로고    scopus 로고
    • Regulation of insulin gene transcription
    • Melloul D, Marshak S, Cerasi E. Regulation of insulin gene transcription. Diabetologia (2002) 45(3):309-26
    • (2002) Diabetologia , vol.45 , Issue.3 , pp. 309-326
    • Melloul, D.1    Marshak, S.2    Cerasi, E.3
  • 11
    • 0028358092 scopus 로고
    • The insulin gene contains multiple transcriptional elements that respond to glucose.
    • German MS, Wang J. The insulin gene contains multiple transcriptional elements that respond to glucose. Mol Cell Biol (1994) 14(6):4067-75
    • (1994) Mol Cell Biol , vol.14 , Issue.6 , pp. 4067-4075
    • German, M.S.1    Wang, J.2
  • 12
    • 0027944249 scopus 로고
    • Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes
    • Petersen HV, Serup P, Leonard J, Michelsen BK, Madsen OD. Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes. Proc Natl Acad Sci USA (1994) 91(22):10465-9
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.22 , pp. 10465-10469
    • Petersen, H.V.1    Serup, P.2    Leonard, J.3    Michelsen, B.K.4    Madsen, O.D.5
  • 13
    • 0030927342 scopus 로고    scopus 로고
    • The beta cell transcription factors and development of the pancreas
    • Sander M, German MS. The beta cell transcription factors and development of the pancreas. J Mol Med (1997) 75(5):327-40
    • (1997) J Mol Med , vol.75 , Issue.5 , pp. 327-340
    • Sander, M.1    German, M.S.2
  • 14
    • 0033962883 scopus 로고    scopus 로고
    • The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter
    • Ohneda K, Mirmira RG, Wang J, Johnson JD, German MS. The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter. Mol Cell Biol (2000) 20(3):900-11
    • (2000) Mol Cell Biol , vol.20 , Issue.3 , pp. 900-911
    • Ohneda, K.1    Mirmira, R.G.2    Wang, J.3    Johnson, J.D.4    German, M.S.5
  • 15
    • 0024454676 scopus 로고
    • A tissue-specific nuclear factor binds to multiple sites in the human insulin-gene enhancer
    • Boam DS, Docherty K. A tissue-specific nuclear factor binds to multiple sites in the human insulin-gene enhancer. Biochem J (1989) 264(1):233-9
    • (1989) Biochem J , vol.264 , Issue.1 , pp. 233-239
    • Boam, D.S.1    Docherty, K.2
  • 16
    • 0027373441 scopus 로고
    • Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells
    • Leonard J, Peers B, Johnson T, Ferreri K, Lee S, Montminy MR. Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol Endocrinol (1993) 7(10):1275-83
    • (1993) Mol Endocrinol , vol.7 , Issue.10 , pp. 1275-1283
    • Leonard, J.1    Peers, B.2    Johnson, T.3    Ferreri, K.4    Lee, S.5    Montminy, M.R.6
  • 17
    • 0027384997 scopus 로고
    • IPF1, a homeodomain-containing transactivator of the insulin gene
    • Ohlsson H, Karlsson K, Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J (1993) 12(11):4251-9
    • (1993) EMBO J , vol.12 , Issue.11 , pp. 4251-4259
    • Ohlsson, H.1    Karlsson, K.2    Edlund, T.3
  • 18
    • 0028314969 scopus 로고
    • IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene
    • Miller CP, McGehee RE Jr, Habener JF. IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J (1994) 13(5):1145-56
    • (1994) EMBO J , vol.13 , Issue.5 , pp. 1145-1156
    • Miller, C.P.1    McGehee R.E, Jr.2    Habener, J.F.3
  • 19
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J, Carlsson L, Edlund T, Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature (1994) 371(6498):606-9
    • (1994) Nature , vol.371 , Issue.6498 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 20
    • 0030447883 scopus 로고    scopus 로고
    • Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells
    • Marshak S, Totary H, Cerasi E, Melloul D. Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells. Proc Natl Acad Sci USA (1996) 93(26):15057-62
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.26 , pp. 15057-15062
    • Marshak, S.1    Totary, H.2    Cerasi, E.3    Melloul, D.4
  • 21
    • 0034775035 scopus 로고    scopus 로고
    • Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function
    • McKinnon CM, Docherty K. Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function. Diabetologia (2001) 44(10):1203-14
    • (2001) Diabetologia , vol.44 , Issue.10 , pp. 1203-1214
    • McKinnon, C.M.1    Docherty, K.2
  • 22
    • 43449091944 scopus 로고    scopus 로고
    • PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function
    • Kaneto H, Miyatsuka T, Kawamori D, Yamamoto K, Kato K, Shiraiwa T, et al. PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function. Endocr J (2008) 55(2):235-52
    • (2008) Endocr J , vol.55 , Issue.2 , pp. 235-252
    • Kaneto, H.1    Miyatsuka, T.2    Kawamori, D.3    Yamamoto, K.4    Kato, K.5    Shiraiwa, T.6
  • 23
    • 0032525981 scopus 로고    scopus 로고
    • Beta-cell specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
    • Ahlgren U, Jonsson J, Jonsson L, Simu K, Edlund H. Beta-cell specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev (1998) 12(12):1763-8
    • (1998) Genes Dev , vol.12 , Issue.12 , pp. 1763-1768
    • Ahlgren, U.1    Jonsson, J.2    Jonsson, L.3    Simu, K.4    Edlund, H.5
  • 24
    • 0031253820 scopus 로고    scopus 로고
    • Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
    • Stoffers DA, Ferrer J, Clarke WL, Habener JF. Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nat Genet (1997) 17(2):138-9
    • (1997) Nat Genet , vol.17 , Issue.2 , pp. 138-139
    • Stoffers, D.A.1    Ferrer, J.2    Clarke, W.L.3    Habener, J.F.4
  • 26
    • 0037076351 scopus 로고    scopus 로고
    • Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA
    • Olbrot M, Rud J, Moss LG, Sharma A. Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA. Proc Natl Acad Sci USA (2002) 99(10):6737-42
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.10 , pp. 6737-6742
    • Olbrot, M.1    Rud, J.2    Moss, L.G.3    Sharma, A.4
  • 27
    • 1542271011 scopus 로고    scopus 로고
    • Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells
    • Kataoka K, Shioda S, Ando K, Sakagami K, Handa H, Yasuda K. Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells. J Mol Endocrinol (2004) 32(1):9-20
    • (2004) J Mol Endocrinol , vol.32 , Issue.1 , pp. 9-20
    • Kataoka, K.1    Shioda, S.2    Ando, K.3    Sakagami, K.4    Handa, H.5    Yasuda, K.6
  • 28
    • 0041970072 scopus 로고    scopus 로고
    • Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells
    • Matsuoka TA, Zhao L, Artner I, Jarrett HW, Friedman D, Means A, et al. Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells. Mol Cell Biol (2003) 23(17):6049-62
    • (2003) Mol Cell Biol , vol.23 , Issue.17 , pp. 6049-6062
    • Matsuoka, T.A.1    Zhao, L.2    Artner, I.3    Jarrett, H.W.4    Friedman, D.5    Means, A.6
  • 30
    • 80052381881 scopus 로고    scopus 로고
    • MafA and MafB activity in pancreatic β cells
    • Hang Y, Stein R. MafA and MafB activity in pancreatic β cells. Trends Endocrinol Metab (2011) 22(9):364-73
    • (2011) Trends Endocrinol Metab , vol.22 , Issue.9 , pp. 364-373
    • Hang, Y.1    Stein, R.2
  • 31
    • 84866115684 scopus 로고    scopus 로고
    • MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells
    • Zhao X, Mohan R, Özcan S, Tang X. MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells. J Biol Chem (2012) 287(37):31155-64
    • (2012) J Biol Chem , vol.287 , Issue.37 , pp. 31155-31164
    • Zhao, X.1    Mohan, R.2    Özcan, S.3    Tang, X.4
  • 32
    • 84881218353 scopus 로고    scopus 로고
    • Inactivation of specific β cell transcription factors in type 2 diabetes
    • Guo S, Dai C, Guo M, Taylor B, Harmon JS, Sander M, et al. Inactivation of specific β cell transcription factors in type 2 diabetes. J Clin Invest (2013) 123(8):3305-16
    • (2013) J Clin Invest , vol.123 , Issue.8 , pp. 3305-3316
    • Guo, S.1    Dai, C.2    Guo, M.3    Taylor, B.4    Harmon, J.S.5    Sander, M.6
  • 33
    • 77957583357 scopus 로고    scopus 로고
    • MafA and MafB regulate genes critical to beta-cells in a unique temporal manner
    • Artner I, Hang Y, Mazur M, Yamamoto T, Guo M, Lindner J, et al. MafA and MafB regulate genes critical to beta-cells in a unique temporal manner. Diabetes (2010) 59(10):2530-9
    • (2010) Diabetes , vol.59 , Issue.10 , pp. 2530-2539
    • Artner, I.1    Hang, Y.2    Mazur, M.3    Yamamoto, T.4    Guo, M.5    Lindner, J.6
  • 34
    • 0030358586 scopus 로고    scopus 로고
    • High-mobility-group chromosomal proteins: architectural components that facilitate chromatin function.
    • Bustin M, Reeves R. High-mobility-group chromosomal proteins: architectural components that facilitate chromatin function. Prog Nucleic Acid Res Mol Biol (1996) 54:35-100
    • (1996) Prog Nucleic Acid Res Mol Biol , vol.54 , pp. 35-100
    • Bustin, M.1    Reeves, R.2
  • 35
    • 0035838991 scopus 로고    scopus 로고
    • Coordination of a transcriptional switch by HMGI(Y) acetylation Science
    • Munshi N, Agalioti T, Lomvardas S, Merika M, Chen G, Thanos D. Coordination of a transcriptional switch by HMGI(Y) acetylation Science (2001) 293(5532):1133-6
    • (2001) , vol.293 , Issue.5532 , pp. 1133-1136
    • Munshi, N.1    Agalioti, T.2    Lomvardas, S.3    Merika, M.4    Chen, G.5    Thanos, D.6
  • 36
    • 0037385239 scopus 로고    scopus 로고
    • A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription
    • Foti D, Iuliano R, Chiefari E, Brunetti A. A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription. Mol Cell Biol (2003) 23(8):2720-32
    • (2003) Mol Cell Biol , vol.23 , Issue.8 , pp. 2720-2732
    • Foti, D.1    Iuliano, R.2    Chiefari, E.3    Brunetti, A.4
  • 37
    • 38849089984 scopus 로고    scopus 로고
    • The HMGA proteins: a myriad of functions
    • Cleynen I, Van de Ven WJ. The HMGA proteins: a myriad of functions. Int J Oncol (2008) 32(2):289-305
    • (2008) Int J Oncol , vol.32 , Issue.2 , pp. 289-305
    • Cleynen, I.1    Van de Ven, W.J.2
  • 38
    • 22544482628 scopus 로고    scopus 로고
    • Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice
    • Foti D, Chiefari E, Fedele M, Iuliano R, Brunetti L, Paonessa F, et al. Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice. Nat Med (2005) 11(7):765-73
    • (2005) Nat Med , vol.11 , Issue.7 , pp. 765-773
    • Foti, D.1    Chiefari, E.2    Fedele, M.3    Iuliano, R.4    Brunetti, L.5    Paonessa, F.6
  • 39
    • 0035128347 scopus 로고    scopus 로고
    • Transcriptional regulation of the insulin receptor by the high mobility group protein HMGI(Y)
    • Brunetti A, Manfioletti G, Chiefari E, Goldfine ID, Foti D. Transcriptional regulation of the insulin receptor by the high mobility group protein HMGI(Y). FASEB J (2001) 15(2):492-500
    • (2001) FASEB J , vol.15 , Issue.2 , pp. 492-500
    • Brunetti, A.1    Manfioletti, G.2    Chiefari, E.3    Goldfine, I.D.4    Foti, D.5
  • 40
    • 0029868156 scopus 로고    scopus 로고
    • PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
    • Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development (1996) 122(3):983-95
    • (1996) Development , vol.122 , Issue.3 , pp. 983-995
    • Offield, M.F.1    Jetton, T.L.2    Labosky, P.A.3    Ray, M.4    Stein, R.W.5    Magnuson, M.A.6
  • 41
    • 0027178671 scopus 로고
    • Identification of unique nuclear regulatory proteins for the insulin receptor gene, which appear during myocyte and adipocyte differentiation
    • Brunetti A, Foti D, Goldfine ID. Identification of unique nuclear regulatory proteins for the insulin receptor gene, which appear during myocyte and adipocyte differentiation. J Clin Invest (1993) 92(3):1288-95
    • (1993) J Clin Invest , vol.92 , Issue.3 , pp. 1288-1295
    • Brunetti, A.1    Foti, D.2    Goldfine, I.D.3
  • 42
    • 0030048931 scopus 로고    scopus 로고
    • Human diabetes associated with defects in regulatory proteins for the insulin receptor gene
    • Brunetti A, Brunetti L, Foti D, Accili D, Goldfine ID. Human diabetes associated with defects in regulatory proteins for the insulin receptor gene. J Clin Invest (1996) 97(1):258-62
    • (1996) J Clin Invest , vol.97 , Issue.1 , pp. 258-262
    • Brunetti, A.1    Brunetti, L.2    Foti, D.3    Accili, D.4    Goldfine, I.D.5
  • 43
    • 33744909111 scopus 로고    scopus 로고
    • Activator protein-2 overexpression accounts for increased insulin receptor expression in human breast cancer
    • Paonessa F, Foti D, Costa V, Chiefari E, Brunetti G, Leone F, et al. Activator protein-2 overexpression accounts for increased insulin receptor expression in human breast cancer. Cancer Res (2006) 66(10):5085-93
    • (2006) Cancer Res , vol.66 , Issue.10 , pp. 5085-5093
    • Paonessa, F.1    Foti, D.2    Costa, V.3    Chiefari, E.4    Brunetti, G.5    Leone, F.6
  • 44
    • 67649881278 scopus 로고    scopus 로고
    • The cAMP502 HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis.
    • Chiefari E, Paonessa F, Iiritano S, Le Pera I, Palmieri D, Brunetti G, et al. The cAMP502 HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis. BMC Biol (2009) 7:24
    • (2009) BMC Biol , vol.7 , pp. 24
    • Chiefari, E.1    Paonessa, F.2    Iiritano, S.3    Le Pera, I.4    Palmieri, D.5    Brunetti, G.6
  • 45
    • 77649182245 scopus 로고    scopus 로고
    • Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas
    • Wang S, Yan J, Anderson DA, Xu Y, Kanal MC, Cao Z, Wright CV, et al. Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas. Dev Biol (2010) 339(1):26-37
    • (2010) Dev Biol , vol.339 , Issue.1 , pp. 26-37
    • Wang, S.1    Yan, J.2    Anderson, D.A.3    Xu, Y.4    Kanal, M.C.5    Cao, Z.6    Wright, C.V.7
  • 46
    • 0037176915 scopus 로고    scopus 로고
    • HMGA1 enhances the transcriptional activity and binding of the estrogen receptor to its responsive element
    • Massaad-Massade L, Navarro S, Krummrei U, Reeves R, Beaune P, Barouki R. HMGA1 enhances the transcriptional activity and binding of the estrogen receptor to its responsive element. Biochemistry (2002) 41(8):2760-8
    • (2002) Biochemistry , vol.41 , Issue.8 , pp. 2760-2768
    • Massaad-Massade, L.1    Navarro, S.2    Krummrei, U.3    Reeves, R.4    Beaune, P.5    Barouki, R.6
  • 47
    • 53149104775 scopus 로고    scopus 로고
    • Glucose regulation of insulin gene expression in pancreatic beta-cells
    • Andrali SS, Sampley ML, Vanderford NL, Ozcan S. Glucose regulation of insulin gene expression in pancreatic beta-cells. Biochem J (2008) 415(1):1-10
    • (2008) Biochem J , vol.415 , Issue.1 , pp. 1-10
    • Andrali, S.S.1    Sampley, M.L.2    Vanderford, N.L.3    Ozcan, S.4
  • 48
    • 79951648091 scopus 로고    scopus 로고
    • Regulation of β-cell-specific and glucose-dependent MafA expression
    • Vanderford NL. Regulation of β-cell-specific and glucose-dependent MafA expression. Islets (2011) 3(1):35-7
    • (2011) Islets , vol.3 , Issue.1 , pp. 35-37
    • Vanderford, N.L.1
  • 49
    • 40749152739 scopus 로고    scopus 로고
    • Reinventing type 2 diabetes: pathogenesis, treatment, and prevention
    • Unger RH. Reinventing type 2 diabetes: pathogenesis, treatment, and prevention. JAMA (2008) 299(10):1185-7
    • (2008) JAMA , vol.299 , Issue.10 , pp. 1185-1187
    • Unger, R.H.1
  • 50
    • 0026634172 scopus 로고
    • A ubiquitous factor is required for C/EBP-related proteins to form stable transcription complexes on an albumin promoter segment in vitro
    • Milos PM, Zaret KS. A ubiquitous factor is required for C/EBP-related proteins to form stable transcription complexes on an albumin promoter segment in vitro. Genes Dev (1992) 6(6):991-1004
    • (1992) Genes Dev , vol.6 , Issue.6 , pp. 991-1004
    • Milos, P.M.1    Zaret, K.S.2
  • 51
    • 0028049833 scopus 로고
    • Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury
    • Eizirik DL, Pipeleers DG, Ling Z, Welsh N, Hellerström C, Andersson A. Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci USA (1994) 91(20):9253-6
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.20 , pp. 9253-9256
    • Eizirik, D.L.1    Pipeleers, D.G.2    Ling, Z.3    Welsh, N.4    Hellerström, C.5    Andersson, A.6
  • 52
    • 0035863135 scopus 로고    scopus 로고
    • Intercellular signals regulating pancreas development and function
    • Kim SK, Hebrok M. Intercellular signals regulating pancreas development and function. Genes Dev (2001) 15(2):111-27
    • (2001) Genes Dev , vol.15 , Issue.2 , pp. 111-127
    • Kim, S.K.1    Hebrok, M.2
  • 53
    • 68749092973 scopus 로고    scopus 로고
    • From bending DNA to diabetes: the curious case of HMGA1.
    • Semple RK. From bending DNA to diabetes: the curious case of HMGA1. J Biol (2009) 8(7):64
    • (2009) J Biol , vol.8 , Issue.7 , pp. 64
    • Semple, R.K.1
  • 54
    • 84856793694 scopus 로고    scopus 로고
    • Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes
    • Chiefari E, Iiritano S, Paonessa F, Le Pera I, Arcidiacono B, Filocamo M, et al. Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes. Nat Commun (2010) 1:40
    • (2010) Nat Commun , vol.1 , pp. 40
    • Chiefari, E.1    Iiritano, S.2    Paonessa, F.3    Le Pera, I.4    Arcidiacono, B.5    Filocamo, M.6
  • 57
    • 84865442111 scopus 로고    scopus 로고
    • Polymorphism of HMGA1 is associated with increased risk of type 2 diabetes among Chinese individuals
    • Liu L, Ding H, Wang HR, Xu YJ, Cui GL, Wang PH, et al. Polymorphism of HMGA1 is associated with increased risk of type 2 diabetes among Chinese individuals. Diabetologia (2012) 55(6):1685-8
    • (2012) Diabetologia , vol.55 , Issue.6 , pp. 1685-1688
    • Liu, L.1    Ding, H.2    Wang, H.R.3    Xu, Y.J.4    Cui, G.L.5    Wang, P.H.6
  • 59
    • 84875795546 scopus 로고    scopus 로고
    • A polymorphism of HMGA1 is associated with increased risk of metabolic syndrome and related components.
    • Chiefari E, Tanyolaç S, Iiritano S, Sciacqua A, Capula C, Arcidiacono B, et al. A polymorphism of HMGA1 is associated with increased risk of metabolic syndrome and related components. Sci Rep (2013) 3:1491
    • (2013) Sci Rep , vol.3 , pp. 1491
    • Chiefari, E.1    Tanyolaç, S.2    Iiritano, S.3    Sciacqua, A.4    Capula, C.5    Arcidiacono, B.6
  • 60
    • 84892557704 scopus 로고    scopus 로고
    • Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population
    • Pullinger CR, Goldfine ID, Tanyolaç S, Movsesyan I, Faynboym M, Durlach V, et al. Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population. Metab Syndr Relat Disord (2014) 12(1):25-30
    • (2014) Metab Syndr Relat Disord , vol.12 , Issue.1 , pp. 25-30
    • Pullinger, C.R.1    Goldfine, I.D.2    Tanyolaç, S.3    Movsesyan, I.4    Faynboym, M.5    Durlach, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.