Polymorphism of HMGA1 is associated with increased risk of type 2 diabetes among Chinese individuals

Diabetologia

Volumn 55, Issue 6, 2012, Pages 1685-1688

  Liu, L ^a   Ding, H ^a   Wang, H R ^a   Xu, Y J ^a   Cui, G L ^a   Wang, P H ^a   Yuan, G ^a   Yu, X F ^a   Wang, D W ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Genetic association; Han chinese population; HMGA1; Type 2 diabetes

Indexed keywords

HIGH MOBILITY GROUP A PROTEIN;

ADULT; ARTICLE; CHINESE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HMGA1 GENE; HUMAN; INTRON; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; AGED; ASIAN; GENETICS; GENOTYPE; MIDDLE AGED;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; DIABETES MELLITUS, TYPE 2; FEMALE; GENOTYPE; HMGA PROTEINS; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC;

EID: 84865442111     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2518-0     Document Type: Article

References (9)

1. Ahlqvist E, Ahluwalia TS, Groop L (2010) Genetics of type 2 diabetes. Clin Chem 57:241-254
2. Taniguchi CM, Emanuelli B, Kahn CR (2006) Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 7:85-96 (Pubitemid 43278292)
3. Foti D, Chiefari E, Fedele M et al (2005) Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice. Nat Med 11:765-773 (Pubitemid 41021209)
4. Chiefari E, Iiritano S, Paonessa F et al (2010) Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes. Nat Commun 1:40-46
5. Chiefari E, Tanyolac S, Paonessa F et al (2011) Functional variants of the HMGA1 gene and type 2 diabetes mellitus. JAMA 305:903-912
6. American Diabetes Association (2008) Standards of medical care in diabetes-2008. Diabetes Care 31(Suppl 1):S12-S54
7. Ding H, Cui G, Zhang L et al (2010) Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population. Pharmacogenet Genomics 20:187-194
8. Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265 (Pubitemid 40202029)
9. Gu D, Reynolds K, Duan X et al (2003) Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterASIA). Diabetologia 46:1190-1198 (Pubitemid 37214976)