-
1
-
-
32544439098
-
Aberrant termination triggers nonsense-mediated mRNA decay
-
Amrani N., Dong S., He F., Ganesan R., Ghosh S., Kervestin S., Li C., Mangus D.A., Spatrick P., Jacobson A. Aberrant termination triggers nonsense-mediated mRNA decay. Biochem. Soc. Trans. 2006, 34:39-42.
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 39-42
-
-
Amrani, N.1
Dong, S.2
He, F.3
Ganesan, R.4
Ghosh, S.5
Kervestin, S.6
Li, C.7
Mangus, D.A.8
Spatrick, P.9
Jacobson, A.10
-
2
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation
-
Apelqvist A., Li H., Sommer L., Beatus P., Anderson D.J., Honjo T., Hrabe de Angelis M., Lendahl U., Edlund H. Notch signalling controls pancreatic cell differentiation. Nature 1999, 400:877-881.
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelqvist, A.1
Li, H.2
Sommer, L.3
Beatus, P.4
Anderson, D.J.5
Honjo, T.6
Hrabe de Angelis, M.7
Lendahl, U.8
Edlund, H.9
-
3
-
-
34247183601
-
MafB is required for islet beta cell maturation
-
Artner I., Blanchi B., Raum J.C., Guo M., Kaneko T., Cordes S., Sieweke M., Stein R. MafB is required for islet beta cell maturation. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:3853-3858.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 3853-3858
-
-
Artner, I.1
Blanchi, B.2
Raum, J.C.3
Guo, M.4
Kaneko, T.5
Cordes, S.6
Sieweke, M.7
Stein, R.8
-
4
-
-
0037343917
-
Single-cell transcript analysis of pancreas development
-
Chiang M.K., Melton D.A. Single-cell transcript analysis of pancreas development. Dev. Cell 2003, 4:383-393.
-
(2003)
Dev. Cell
, vol.4
, pp. 383-393
-
-
Chiang, M.K.1
Melton, D.A.2
-
5
-
-
2342510386
-
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
-
Dor Y., Brown J., Martinez O.I., Melton D.A. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 2004, 429:41-46.
-
(2004)
Nature
, vol.429
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
6
-
-
33645080922
-
Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas
-
Fujikura J., Hosoda K., Iwakura H., Tomita T., Noguchi M., Masuzaki H., Tanigaki K., Yabe D., Honjo T., Nakao K. Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas. Cell Metab. 2006, 3:59-65.
-
(2006)
Cell Metab.
, vol.3
, pp. 59-65
-
-
Fujikura, J.1
Hosoda, K.2
Iwakura, H.3
Tomita, T.4
Noguchi, M.5
Masuzaki, H.6
Tanigaki, K.7
Yabe, D.8
Honjo, T.9
Nakao, K.10
-
7
-
-
68349113777
-
Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas
-
Golson M.L., Le Lay J., Gao N., Bramswig N., Loomes K.M., Oakey R., May C.L., White P., Kaestner K.H. Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech. Dev. 2009, 126:687-699.
-
(2009)
Mech. Dev.
, vol.126
, pp. 687-699
-
-
Golson, M.L.1
Le Lay, J.2
Gao, N.3
Bramswig, N.4
Loomes, K.M.5
Oakey, R.6
May, C.L.7
White, P.8
Kaestner, K.H.9
-
8
-
-
0034652287
-
Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
Gradwohl G., Dierich A., LeMeur M., Guillemot F. neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:1607-1611.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
Guillemot, F.4
-
9
-
-
0035112448
-
Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes
-
Grapin-Botton A., Majithia A.R., Melton D.A. Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes. Genes Dev. 2001, 15:444-454.
-
(2001)
Genes Dev.
, vol.15
, pp. 444-454
-
-
Grapin-Botton, A.1
Majithia, A.R.2
Melton, D.A.3
-
10
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
Gu G., Dubauskaite J., Melton D.A. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002, 129:2447-2457.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
11
-
-
1642474003
-
Global expression analysis of gene regulatory pathways during endocrine pancreatic development
-
Gu G., Wells J.M., Dombkowski D., Preffer F., Aronow B., Melton D.A. Global expression analysis of gene regulatory pathways during endocrine pancreatic development. Development 2004, 131:165-179.
-
(2004)
Development
, vol.131
, pp. 165-179
-
-
Gu, G.1
Wells, J.M.2
Dombkowski, D.3
Preffer, F.4
Aronow, B.5
Melton, D.A.6
-
12
-
-
0034121735
-
Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages
-
Herrera P.L. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 2000, 127:2317-2322.
-
(2000)
Development
, vol.127
, pp. 2317-2322
-
-
Herrera, P.L.1
-
13
-
-
0033996527
-
Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3
-
Huang H.P., Liu M., El-Hodiri H.M., Chu K., Jamrich M., Tsai M.J. Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Mol. Cell. Biol. 2000, 20:3292-3307.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3292-3307
-
-
Huang, H.P.1
Liu, M.2
El-Hodiri, H.M.3
Chu, K.4
Jamrich, M.5
Tsai, M.J.6
-
14
-
-
0033984886
-
Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation
-
Jensen J., Heller R.S., Funder-Nielsen T., Pedersen E.E., Lindsell C., Weinmaster G., Madsen O.D., Serup P. Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation. Diabetes 2000, 49:163-176.
-
(2000)
Diabetes
, vol.49
, pp. 163-176
-
-
Jensen, J.1
Heller, R.S.2
Funder-Nielsen, T.3
Pedersen, E.E.4
Lindsell, C.5
Weinmaster, G.6
Madsen, O.D.7
Serup, P.8
-
15
-
-
18544404101
-
Control of endodermal endocrine development by Hes-1
-
Jensen J., Pedersen E.E., Galante P., Hald J., Heller R.S., Ishibashi M., Kageyama R., Guillemot F., Serup P., Madsen O.D. Control of endodermal endocrine development by Hes-1. Nat. Genet. 2000, 24:36-44.
-
(2000)
Nat. Genet.
, vol.24
, pp. 36-44
-
-
Jensen, J.1
Pedersen, E.E.2
Galante, P.3
Hald, J.4
Heller, R.S.5
Ishibashi, M.6
Kageyama, R.7
Guillemot, F.8
Serup, P.9
Madsen, O.D.10
-
16
-
-
33847217554
-
Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types
-
Johansson K.A., Dursun U., Jordan N., Gu G., Beermann F., Gradwohl G., Grapin-Botton A. Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev. Cell 2007, 12:457-465.
-
(2007)
Dev. Cell
, vol.12
, pp. 457-465
-
-
Johansson, K.A.1
Dursun, U.2
Jordan, N.3
Gu, G.4
Beermann, F.5
Gradwohl, G.6
Grapin-Botton, A.7
-
17
-
-
54949151933
-
Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition
-
Kageyama R., Ohtsuka T., Shimojo H., Imayoshi I. Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition. Nat. Neurosci. 2008, 11:1247-1251.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 1247-1251
-
-
Kageyama, R.1
Ohtsuka, T.2
Shimojo, H.3
Imayoshi, I.4
-
18
-
-
0036730427
-
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
-
Kawaguchi Y., Cooper B., Gannon M., Ray M., MacDonald R.J., Wright C.V. The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat. Genet. 2002, 32:128-134.
-
(2002)
Nat. Genet.
, vol.32
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
Ray, M.4
MacDonald, R.J.5
Wright, C.V.6
-
19
-
-
0037097981
-
Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity
-
Lee C.S., Perreault N., Brestelli J.E., Kaestner K.H. Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Genes Dev. 2002, 16:1488-1497.
-
(2002)
Genes Dev.
, vol.16
, pp. 1488-1497
-
-
Lee, C.S.1
Perreault, N.2
Brestelli, J.E.3
Kaestner, K.H.4
-
20
-
-
0032242705
-
Notch signalling and the control of cell fate choices in vertebrates
-
Lewis J. Notch signalling and the control of cell fate choices in vertebrates. Semin. Cell Dev. Biol. 1998, 9:583-589.
-
(1998)
Semin. Cell Dev. Biol.
, vol.9
, pp. 583-589
-
-
Lewis, J.1
-
21
-
-
0033561410
-
Z/AP, a double reporter for cre-mediated recombination
-
Lobe C.G., Koop K.E., Kreppner W., Lomeli H., Gertsenstein M., Nagy A. Z/AP, a double reporter for cre-mediated recombination. Dev. Biol. 1999, 208:281-292.
-
(1999)
Dev. Biol.
, vol.208
, pp. 281-292
-
-
Lobe, C.G.1
Koop, K.E.2
Kreppner, W.3
Lomeli, H.4
Gertsenstein, M.5
Nagy, A.6
-
22
-
-
0016209638
-
Applications of a theory of biological pattern formation based on lateral inhibition
-
Meinhardt H., Gierer A. Applications of a theory of biological pattern formation based on lateral inhibition. J. Cell Sci. 1974, 15:321-346.
-
(1974)
J. Cell Sci.
, vol.15
, pp. 321-346
-
-
Meinhardt, H.1
Gierer, A.2
-
23
-
-
8344225224
-
Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice
-
Mellitzer G., Martin M., Sidhoum-Jenny M., Orvain C., Barths J., Seymour P.A., Sander M., Gradwohl G. Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice. Mol. Endocrinol. 2004, 18:2765-2776.
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 2765-2776
-
-
Mellitzer, G.1
Martin, M.2
Sidhoum-Jenny, M.3
Orvain, C.4
Barths, J.5
Seymour, P.A.6
Sander, M.7
Gradwohl, G.8
-
24
-
-
33645281942
-
IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas
-
Mellitzer G., Bonne S., Luco R.F., Van De Casteele M., Lenne-Samuel N., Collombat P., Mansouri A., Lee J., Lan M., Pipeleers D., et al. IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas. EMBO J. 2006, 25:1344-1352.
-
(2006)
EMBO J.
, vol.25
, pp. 1344-1352
-
-
Mellitzer, G.1
Bonne, S.2
Luco, R.F.3
Van De Casteele, M.4
Lenne-Samuel, N.5
Collombat, P.6
Mansouri, A.7
Lee, J.8
Lan, M.9
Pipeleers, D.10
-
25
-
-
0037119430
-
Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe
-
Panin V.M., Shao L., Lei L., Moloney D.J., Irvine K.D., Haltiwanger R.S. Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe. J. Biol. Chem. 2002, 277:29945-29952.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29945-29952
-
-
Panin, V.M.1
Shao, L.2
Lei, L.3
Moloney, D.J.4
Irvine, K.D.5
Haltiwanger, R.S.6
-
26
-
-
33750369213
-
The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice
-
Petri A., Ahnfelt-Ronne J., Frederiksen K.S., Edwards D.G., Madsen D., Serup P., Fleckner J., Heller R.S. The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice. J. Mol. Endocrinol. 2006, 37:301-316.
-
(2006)
J. Mol. Endocrinol.
, vol.37
, pp. 301-316
-
-
Petri, A.1
Ahnfelt-Ronne, J.2
Frederiksen, K.S.3
Edwards, D.G.4
Madsen, D.5
Serup, P.6
Fleckner, J.7
Heller, R.S.8
-
27
-
-
84924133024
-
The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity
-
Pin C.L., Rukstalis J.M., Johnson C., Konieczny S.F. The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J. Cell Biol. 2001, 155:519-530.
-
(2001)
J. Cell Biol.
, vol.155
, pp. 519-530
-
-
Pin, C.L.1
Rukstalis, J.M.2
Johnson, C.3
Konieczny, S.F.4
-
28
-
-
33745863033
-
Islet beta cell failure in type 2 diabetes
-
Prentki M., Nolan C.J. Islet beta cell failure in type 2 diabetes. J. Clin. Invest. 2006, 116:1802-1812.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1802-1812
-
-
Prentki, M.1
Nolan, C.J.2
-
29
-
-
2942615168
-
Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types
-
Schonhoff S.E., Giel-Moloney M., Leiter A.B. Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types. Dev. Biol. 2004, 270:443-454.
-
(2004)
Dev. Biol.
, vol.270
, pp. 443-454
-
-
Schonhoff, S.E.1
Giel-Moloney, M.2
Leiter, A.B.3
-
30
-
-
0033825383
-
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
-
Schwitzgebel V.M., Scheel D.W., Conners J.R., Kalamaras J., Lee J.E., Anderson D.J., Sussel L., Johnson J.D., German M.S. Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 2000, 127:3533-3542.
-
(2000)
Development
, vol.127
, pp. 3533-3542
-
-
Schwitzgebel, V.M.1
Scheel, D.W.2
Conners, J.R.3
Kalamaras, J.4
Lee, J.E.5
Anderson, D.J.6
Sussel, L.7
Johnson, J.D.8
German, M.S.9
-
31
-
-
33846910410
-
SOX9 is required for maintenance of the pancreatic progenitor cell pool
-
Seymour P.A., Freude K.K., Tran M.N., Mayes E.E., Jensen J., Kist R., Scherer G., Sander M. SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:1865-1870.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 1865-1870
-
-
Seymour, P.A.1
Freude, K.K.2
Tran, M.N.3
Mayes, E.E.4
Jensen, J.5
Kist, R.6
Scherer, G.7
Sander, M.8
-
32
-
-
0033986128
-
Getting to the guts of enteroendocrine differentiation
-
Skipper M., Lewis J. Getting to the guts of enteroendocrine differentiation. Nat. Genet. 2000, 24:3-4.
-
(2000)
Nat. Genet.
, vol.24
, pp. 3-4
-
-
Skipper, M.1
Lewis, J.2
-
33
-
-
3042856262
-
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
-
Srinivas S., Watanabe T., Lin C.S., William C.M., Tanabe Y., Jessell T.M., Costantini F. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev. Biol. 2001, 1:4.
-
(2001)
BMC Dev. Biol.
, vol.1
, pp. 4
-
-
Srinivas, S.1
Watanabe, T.2
Lin, C.S.3
William, C.M.4
Tanabe, Y.5
Jessell, T.M.6
Costantini, F.7
-
34
-
-
33847210675
-
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver
-
Stanger B.Z., Tanaka A.J., Melton D.A. Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver. Nature 2007, 445:886-891.
-
(2007)
Nature
, vol.445
, pp. 886-891
-
-
Stanger, B.Z.1
Tanaka, A.J.2
Melton, D.A.3
-
35
-
-
64649093843
-
MFng is dispensable for mouse pancreas development and function
-
Svensson P., Bergqvist I., Norlin S., Edlund H. MFng is dispensable for mouse pancreas development and function. Mol. Cell. Biol. 2009, 29:2129-2138.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 2129-2138
-
-
Svensson, P.1
Bergqvist, I.2
Norlin, S.3
Edlund, H.4
-
36
-
-
55549147549
-
Biphasic Ngn3 expression in the developing pancreas
-
Villasenor A., Chong D.C., Cleaver O. Biphasic Ngn3 expression in the developing pancreas. Dev. Dyn. 2008, 237:3270-3279.
-
(2008)
Dev. Dyn.
, vol.237
, pp. 3270-3279
-
-
Villasenor, A.1
Chong, D.C.2
Cleaver, O.3
-
37
-
-
43049145766
-
Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation
-
Wang S., Hecksher-Sorensen J., Xu Y., Zhao A., Dor Y., Rosenberg L., Serup P., Gu G. Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation. Dev. Biol. 2008, 317:531-540.
-
(2008)
Dev. Biol.
, vol.317
, pp. 531-540
-
-
Wang, S.1
Hecksher-Sorensen, J.2
Xu, Y.3
Zhao, A.4
Dor, Y.5
Rosenberg, L.6
Serup, P.7
Gu, G.8
-
38
-
-
35748956880
-
Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse
-
Wang S., Zhang J., Zhao A., Hipkens S., Magnuson M.A., Gu G. Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse. Mech. Dev. 2007, 124:898-910.
-
(2007)
Mech. Dev.
, vol.124
, pp. 898-910
-
-
Wang, S.1
Zhang, J.2
Zhao, A.3
Hipkens, S.4
Magnuson, M.A.5
Gu, G.6
-
39
-
-
67649865643
-
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function
-
Wang S., Jensen J.N., Seymour P.A., Hsu W., Dor Y., Sander M., Magnuson M.A., Serup P., Gu G. Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:9715-9720.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 9715-9720
-
-
Wang, S.1
Jensen, J.N.2
Seymour, P.A.3
Hsu, W.4
Dor, Y.5
Sander, M.6
Magnuson, M.A.7
Serup, P.8
Gu, G.9
-
40
-
-
40949142371
-
Defining pancreatic endocrine precursors and their descendants
-
White P., May C.L., Lamounier R.N., Brestelli J.E., Kaestner K.H. Defining pancreatic endocrine precursors and their descendants. Diabetes 2008, 57:654-668.
-
(2008)
Diabetes
, vol.57
, pp. 654-668
-
-
White, P.1
May, C.L.2
Lamounier, R.N.3
Brestelli, J.E.4
Kaestner, K.H.5
-
41
-
-
62649093531
-
Chemicals turn human embryonic stem cells towards beta cells
-
Yang Y.P., Wright C. Chemicals turn human embryonic stem cells towards beta cells. Nat. Chem. Biol. 2009, 5:195-196.
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 195-196
-
-
Yang, Y.P.1
Wright, C.2
-
42
-
-
65349105337
-
Using small molecules to great effect in stem cell differentiation
-
Zaret K.S. Using small molecules to great effect in stem cell differentiation. Cell Stem Cell 2009, 4:373-374.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 373-374
-
-
Zaret, K.S.1
-
43
-
-
34250893048
-
A multipotent progenitor domain guides pancreatic organogenesis
-
Zhou Q., Law A.C., Rajagopal J., Anderson W.J., Gray P.A., Melton D.A. A multipotent progenitor domain guides pancreatic organogenesis. Dev. Cell 2007, 13:103-114.
-
(2007)
Dev. Cell
, vol.13
, pp. 103-114
-
-
Zhou, Q.1
Law, A.C.2
Rajagopal, J.3
Anderson, W.J.4
Gray, P.A.5
Melton, D.A.6
-
44
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou Q., Brown J., Kanarek A., Rajagopal J., Melton D.A. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008, 455:627-632.
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(2008)
Nature
, vol.455
, pp. 627-632
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Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
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