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Volumn 20, Issue 3, 2000, Pages 900-911

The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN; HIGH MOBILITY GROUP PROTEIN; HOMEODOMAIN PROTEIN; INSULIN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

EID: 0033962883     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.3.900-911.2000     Document Type: Article
Times cited : (171)

References (53)
  • 1
    • 0031787987 scopus 로고    scopus 로고
    • High mobility group I/Y protein functions as a specific cofactor for Oct-2A: Mapping of interaction domains
    • Abdulkadir, S. A., V. Casolaro, A. K. Tai, D. Thanos, and S. J. Ono. 1998. High mobility group I/Y protein functions as a specific cofactor for Oct-2A: mapping of interaction domains. J. Leukoc. Biol. 64:681-691.
    • (1998) J. Leukoc. Biol. , vol.64 , pp. 681-691
    • Abdulkadir, S.A.1    Casolaro, V.2    Tai, A.K.3    Thanos, D.4    Ono, S.J.5
  • 2
    • 0029950724 scopus 로고    scopus 로고
    • The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice
    • Ahlgren, U., J. Jonsson, and H. Edlund. 1996. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice. Development 122:1409-1416.
    • (1996) Development , vol.122 , pp. 1409-1416
    • Ahlgren, U.1    Jonsson, J.2    Edlund, H.3
  • 3
    • 0032525981 scopus 로고    scopus 로고
    • β-Cell-specific inactivation of the mouse ipf1/Pdx1 gene results in loss of the β-cell phenotype and maturity onset diabetes
    • Ahlgren, U., J. Jonsson, L. Jonsson, K. Simu, and H. Edlund. 1998. β-Cell-specific inactivation of the mouse ipf1/Pdx1 gene results in loss of the β-cell phenotype and maturity onset diabetes. Genes Dev. 12:1763-1768.
    • (1998) Genes Dev. , vol.12 , pp. 1763-1768
    • Ahlgren, U.1    Jonsson, J.2    Jonsson, L.3    Simu, K.4    Edlund, H.5
  • 5
    • 0027204066 scopus 로고
    • The E2A gene product contains two separable and functionally distinct transcription activation domains
    • Aronheim, A., R. Shiran, A. Rosen, and M. D. Walker. 1993. The E2A gene product contains two separable and functionally distinct transcription activation domains. Proc. Natl. Acad. Sci. USA 90:8063-8067.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8063-8067
    • Aronheim, A.1    Shiran, R.2    Rosen, A.3    Walker, M.D.4
  • 6
    • 0025323711 scopus 로고
    • Structural features of the HMG chromosomal proteins and their genes
    • Bustin, M., D. A. Lehn, and D. Landsman. 1990. Structural features of the HMG chromosomal proteins and their genes. Biochim. Biophys. Acta 1049: 231-243.
    • (1990) Biochim. Biophys. Acta , vol.1049 , pp. 231-243
    • Bustin, M.1    Lehn, D.A.2    Landsman, D.3
  • 7
    • 0032498230 scopus 로고    scopus 로고
    • The enhanceosome and transcriptional synergy
    • Carey, M. 1998. The enhanceosome and transcriptional synergy. Cell 92:5-8.
    • (1998) Cell , vol.92 , pp. 5-8
    • Carey, M.1
  • 8
    • 0027966927 scopus 로고
    • The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein
    • Chan, S. K., L. Jaffe, M. Capovilla, J. Botas, and R. S. Mann. 1994. The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein. Cell 78:603-615.
    • (1994) Cell , vol.78 , pp. 603-615
    • Chan, S.K.1    Jaffe, L.2    Capovilla, M.3    Botas, J.4    Mann, R.S.5
  • 9
    • 0030001136 scopus 로고    scopus 로고
    • Insulin gene: Organisation, expression and regulation
    • Dumonteil, E., and J. Philippe. 1996. Insulin gene: organisation, expression and regulation. Diabetes Metab. 22:164-173.
    • (1996) Diabetes Metab. , vol.22 , pp. 164-173
    • Dumonteil, E.1    Philippe, J.2
  • 10
    • 0030799792 scopus 로고    scopus 로고
    • The cardiac transcription factors Nkx2-5 and GATA-4 are mutural cofactors
    • Durocher, D., F. Charron, R. Warren, R. J. Schwartz, and M. Nemer. 1997. The cardiac transcription factors Nkx2-5 and GATA-4 are mutural cofactors. EMBO J. 18:5687-5696.
    • (1997) EMBO J. , vol.18 , pp. 5687-5696
    • Durocher, D.1    Charron, F.2    Warren, R.3    Schwartz, R.J.4    Nemer, M.5
  • 11
    • 0029825698 scopus 로고    scopus 로고
    • Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation
    • Eckner, R., T. P. Yao, E. Oldread, and D. M. Livingston. 1996. Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes Dev. 10:2478-2490.
    • (1996) Genes Dev. , vol.10 , pp. 2478-2490
    • Eckner, R.1    Yao, T.P.2    Oldread, E.3    Livingston, D.M.4
  • 12
    • 0026742624 scopus 로고
    • Hepatocyte nuclear factor 1α is expressed in a hamster insulinoma line and transactivates the rat insulin I gene
    • Emens, L. A., D. W. Landers, and L. G. Moss. 1992. Hepatocyte nuclear factor 1α is expressed in a hamster insulinoma line and transactivates the rat insulin I gene. Proc. Natl. Acad. Sci. USA 89:7300-7304.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7300-7304
    • Emens, L.A.1    Landers, D.W.2    Moss, L.G.3
  • 14
    • 0026016780 scopus 로고
    • Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer
    • German, M. S., M. A. Blanar, C. Nelson, L. G. Moss, and W. J. Rutter. 1991. Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer. Mol. Endocrinol. 5:292-299.
    • (1991) Mol. Endocrinol. , vol.5 , pp. 292-299
    • German, M.S.1    Blanar, M.A.2    Nelson, C.3    Moss, L.G.4    Rutter, W.J.5
  • 15
    • 0026602931 scopus 로고
    • The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes
    • German, M. S., L. G. Moss, J. Wang, and W. J. Rutter. 1992. The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes. Mol. Cell. Biol. 12: 1777-1788.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1777-1788
    • German, M.S.1    Moss, L.G.2    Wang, J.3    Rutter, W.J.4
  • 16
    • 0026471057 scopus 로고
    • Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: Building a functional insulin minienhancer complex
    • German, M. S., J. Wang, R. B. Chadwick, and W. J. Rutter. 1992. Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex. Genes Dev. 6:2165-2176.
    • (1992) Genes Dev. , vol.6 , pp. 2165-2176
    • German, M.S.1    Wang, J.2    Chadwick, R.B.3    Rutter, W.J.4
  • 17
    • 0029060412 scopus 로고
    • Higher-order nucleoprotein complexes in transcription: Analogies with site-specific recombination
    • Grosschedl, R. 1995. Higher-order nucleoprotein complexes in transcription: analogies with site-specific recombination. Curr. Opin. Cell Biol. 7:362-370.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 362-370
    • Grosschedl, R.1
  • 18
    • 0028197368 scopus 로고
    • HMG domain proteins: Architectural elements in the assembly of nucleoprotein structures
    • Grosschedl, R., K. Giese, and J. Pagel. 1994. HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. Trends Genet. 10:94-100.
    • (1994) Trends Genet. , vol.10 , pp. 94-100
    • Grosschedl, R.1    Giese, K.2    Pagel, J.3
  • 19
    • 0021888904 scopus 로고
    • Heritable formation of pancreatic β-cell tumors in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes
    • Hanahan, D. 1985. Heritable formation of pancreatic β-cell tumors in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature 315:115-122.
    • (1985) Nature , vol.315 , pp. 115-122
    • Hanahan, D.1
  • 20
    • 0031011850 scopus 로고    scopus 로고
    • Transcriptional synergy between LIM-homeodomain proteins and basic helix-loop-helix proteins: The LIM2 domain determines specificity
    • Johnson, J. D., W. Zhang, A. Rudnick, W. J. Rutter, and M. S. German. 1997. Transcriptional synergy between LIM-homeodomain proteins and basic helix-loop-helix proteins: the LIM2 domain determines specificity. Mol. Cell. Biol. 17:3488-3496.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3488-3496
    • Johnson, J.D.1    Zhang, W.2    Rudnick, A.3    Rutter, W.J.4    German, M.S.5
  • 21
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson, J., L. Carlsson, T. Edlund, and H. Edlund. 1994. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371:606-609.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 22
    • 0025280050 scopus 로고
    • Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain
    • Karlsson, O., S. Thor, T. Norberg, H. Ohlsson, and T. Edlund. 1990. Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain. Nature 344:879-882.
    • (1990) Nature , vol.344 , pp. 879-882
    • Karlsson, O.1    Thor, S.2    Norberg, T.3    Ohlsson, H.4    Edlund, T.5
  • 23
    • 0024494832 scopus 로고
    • Individual protein-binding domains of the insulin gene enhancer positively activate β-cell-specific transcription
    • Karlsson, O., M. D. Walker, W. J. Rutter, and T. Edlund. 1989. Individual protein-binding domains of the insulin gene enhancer positively activate β-cell-specific transcription. Mol. Cell. Biol. 9:823-827.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 823-827
    • Karlsson, O.1    Walker, M.D.2    Rutter, W.J.3    Edlund, T.4
  • 24
    • 0002135521 scopus 로고    scopus 로고
    • Insulin gene regulation
    • D. LeRoith, J. Olefsky, and S. Taylor (ed.), Lippincott-Raven Publishers, Philadelphia, Pa
    • Kennedy, G., and M. German. 1996. Insulin gene regulation, p. 20-26. In D. LeRoith, J. Olefsky, and S. Taylor (ed.), Diabetes mellitus: a fundamental and clinical text. Lippincott-Raven Publishers, Philadelphia, Pa.
    • (1996) Diabetes Mellitus: A Fundamental and Clinical Text , pp. 20-26
    • Kennedy, G.1    German, M.2
  • 25
    • 0031310825 scopus 로고    scopus 로고
    • The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome
    • Kim, T. K., and T. Maniatis. 1997. The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome. Mol. Cell 1:119-129.
    • (1997) Mol. Cell , vol.1 , pp. 119-129
    • Kim, T.K.1    Maniatis, T.2
  • 26
    • 0031844382 scopus 로고    scopus 로고
    • The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression
    • Lee, Y., T. Shioi, H. Kasahara, S. M. Jobe, R. J. Wiese, B. E. Markham, and S. Izumo. 1998. The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression. Mol. Cell. Biol. 18:3120-3129.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3120-3129
    • Lee, Y.1    Shioi, T.2    Kasahara, H.3    Jobe, S.M.4    Wiese, R.J.5    Markham, B.E.6    Izumo, S.7
  • 27
    • 0029017459 scopus 로고
    • Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y
    • Leger, H., E. Sock, K. Renner, F. Grummt, and M. Wegner. 1995. Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y. Mol. Cell. Biol. 15:3738-3747.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3738-3747
    • Leger, H.1    Sock, E.2    Renner, K.3    Grummt, F.4    Wegner, M.5
  • 28
    • 0027373441 scopus 로고
    • Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells
    • Leonard, J., B. Peers, T. Johnson, K. Ferreri, S. Lee, and M. R. Montminy. 1993. Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol. Endocrinol. 7:1275-1283.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1275-1283
    • Leonard, J.1    Peers, B.2    Johnson, T.3    Ferreri, K.4    Lee, S.5    Montminy, M.R.6
  • 29
    • 0028006811 scopus 로고
    • Glucose modulates the binding activity of the beta-cell transcription factor IUF1 in a phosphorylation-dependent manner
    • MacFarlane, W., M. Read, M. Gilligan, I. Bujalska, and K. Docherty. 1994. Glucose modulates the binding activity of the beta-cell transcription factor IUF1 in a phosphorylation-dependent manner. Biochem. J. 303:625-631.
    • (1994) Biochem. J. , vol.303 , pp. 625-631
    • MacFarlane, W.1    Read, M.2    Gilligan, M.3    Bujalska, I.4    Docherty, K.5
  • 30
    • 0030447883 scopus 로고    scopus 로고
    • Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells
    • Marshak, S., H. Totary, E. Cerasi, and D. Melloul. 1996. Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells. Proc. Natl. Acad. Sci. USA 93:15057-15062.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15057-15062
    • Marshak, S.1    Totary, H.2    Cerasi, E.3    Melloul, D.4
  • 31
    • 0029655318 scopus 로고    scopus 로고
    • The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells
    • Massari, M. E., P. A. Jennings, and C. Murre. 1996. The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells. Mol. Cell. Biol. 16:121-129.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 121-129
    • Massari, M.E.1    Jennings, P.A.2    Murre, C.3
  • 32
    • 0028314969 scopus 로고
    • IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene
    • Miller, C. P., R. E. McGehee, Jr., and J. F. Habener. 1994. IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J. 13:1145-1156.
    • (1994) EMBO J. , vol.13 , pp. 1145-1156
    • Miller, C.P.1    McGehee R.E., Jr.2    Habener, J.F.3
  • 33
    • 0001032841 scopus 로고
    • The helix-loop-helix motif: Structure and function
    • S. L. McKnight and K. R. Yamamoto (ed.). Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
    • Murre, C., and D. Baltimore. 1992. The helix-loop-helix motif: structure and function, p. 861-879. In S. L. McKnight and K. R. Yamamoto (ed.), Transcriptional regulation. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
    • (1992) Transcriptional Regulation , pp. 861-879
    • Murre, C.1    Baltimore, D.2
  • 34
    • 0030887841 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression
    • Mutoh, H., B. P. Fung, F. J. Naya, M. J. Tsai, J. Nishitani, and A. B. Leiter. 1997. The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression. Proc. Natl. Acad. Sci. USA 94:3560-3564.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3560-3564
    • Mutoh, H.1    Fung, B.P.2    Naya, F.J.3    Tsai, M.J.4    Nishitani, J.5    Leiter, A.B.6
  • 35
    • 0028941181 scopus 로고
    • Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor
    • Naya, F. J., C. M. Stellrecht, and M. J. Tsai. 1995. Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev. 9:1009-1019.
    • (1995) Genes Dev. , vol.9 , pp. 1009-1019
    • Naya, F.J.1    Stellrecht, C.M.2    Tsai, M.J.3
  • 37
    • 0027384997 scopus 로고
    • IPF1, a homeodomain-containing transactivator of the insulin gene
    • Ohlsson, H., K. Karlsson, and T. Edlund. 1993. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J. 12:4251-4259.
    • (1993) EMBO J. , vol.12 , pp. 4251-4259
    • Ohlsson, H.1    Karlsson, K.2    Edlund, T.3
  • 38
    • 0028567837 scopus 로고
    • Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1
    • Peers, B., J. Leonard, S. Sharma, G. Teitelman, and M. R. Montminy. 1994. Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol. Endocrinol. 8:1798-1806.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1798-1806
    • Peers, B.1    Leonard, J.2    Sharma, S.3    Teitelman, G.4    Montminy, M.R.5
  • 39
    • 0028868441 scopus 로고
    • The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: Importance of the FPWMK motif and of the homeodomain
    • Peers, B., S. Sharma, T. Johnson, M. Kamps, and M. Monteminy. 1995. The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain. Mol. Cell. Biol. 15:7091-7097.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 7091-7097
    • Peers, B.1    Sharma, S.2    Johnson, T.3    Kamps, M.4    Monteminy, M.5
  • 40
    • 0031009805 scopus 로고    scopus 로고
    • Functional characterization of the transactivation properties of the PDX-1 homeodomain protein
    • Peshavaria, M., E. Henderson, A. Sharma, C. V. Wright, and R. Stein. 1997. Functional characterization of the transactivation properties of the PDX-1 homeodomain protein. Mol. Cell. Biol. 17:3987-3996.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3987-3996
    • Peshavaria, M.1    Henderson, E.2    Sharma, A.3    Wright, C.V.4    Stein, R.5
  • 41
    • 0031943003 scopus 로고    scopus 로고
    • p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene
    • Qiu, Y., A. Sharma, and R. Stein. 1998. p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene. Mol. Cell. Biol. 18:2957-2964.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2957-2964
    • Qiu, Y.1    Sharma, A.2    Stein, R.3
  • 43
    • 0031815073 scopus 로고    scopus 로고
    • GATA-4 and Nkx-2.5 coactive Nkx-2 DNA binding targets: Role for regulating early cardiac gene expression
    • Sepulveda, J. L., N. Belaguli, V. Nigam, C. Y. Chen, M. Nemer, and R. J. Schwartz. 1998. GATA-4 and Nkx-2.5 coactive Nkx-2 DNA binding targets: role for regulating early cardiac gene expression. Mol. Cell. Biol. 18:3405-3415.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3405-3415
    • Sepulveda, J.L.1    Belaguli, N.2    Nigam, V.3    Chen, C.Y.4    Nemer, M.5    Schwartz, R.J.6
  • 44
    • 0029166081 scopus 로고
    • The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site
    • Serup, P., H. V. Petersen, E. E. Pedersen, H. Edlund, J. Leonard, J. S. Petersen, L. I. Larsson, and O. D. Madsen. 1995. The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site. Biochem. J. 310:997-1003.
    • (1995) Biochem. J. , vol.310 , pp. 997-1003
    • Serup, P.1    Petersen, H.V.2    Pedersen, E.E.3    Edlund, H.4    Leonard, J.5    Petersen, J.S.6    Larsson, L.I.7    Madsen, O.D.8
  • 45
    • 0030911386 scopus 로고    scopus 로고
    • A direct contact between the dorsal rel homology domain and Twist may mediate transcriptional synergy
    • Shirokawa, J. M., and A. J. Courey. 1997. A direct contact between the dorsal rel homology domain and Twist may mediate transcriptional synergy. Mol. Cell. Biol. 17:3345-3355.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3345-3355
    • Shirokawa, J.M.1    Courey, A.J.2
  • 46
    • 0031031571 scopus 로고    scopus 로고
    • Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
    • Stoffers, D. A., N. T. Zinkin, V. Stanojevic, W. L. Clarke, and J. F. Habener. 1997. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat. Genet. 15:106-110.
    • (1997) Nat. Genet. , vol.15 , pp. 106-110
    • Stoffers, D.A.1    Zinkin, N.T.2    Stanojevic, V.3    Clarke, W.L.4    Habener, J.F.5
  • 47
    • 0029617947 scopus 로고
    • Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome
    • Thanos, D., and T. Maniatis. 1995. Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome. Cell 83:1091-1100.
    • (1995) Cell , vol.83 , pp. 1091-1100
    • Thanos, D.1    Maniatis, T.2
  • 48
    • 0028169993 scopus 로고
    • Extradenticle raises the DNA binding specificity of homeotic selector gene products
    • van Dijk, M. A., and C. Murre. 1994. extradenticle raises the DNA binding specificity of homeotic selector gene products. Cell 78:617-624.
    • (1994) Cell , vol.78 , pp. 617-624
    • Van Dijk, M.A.1    Murre, C.2
  • 49
    • 0030457705 scopus 로고    scopus 로고
    • Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor
    • Waeber, G., N. Thompson, P. Nicod, and C. Bonny. 1996. Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor. Mol. Endocrinol. 10:1327-1334.
    • (1996) Mol. Endocrinol. , vol.10 , pp. 1327-1334
    • Waeber, G.1    Thompson, N.2    Nicod, P.3    Bonny, C.4
  • 50
    • 0021071029 scopus 로고
    • Cell-specific expression controlled by the 5' flanking regions of the insulin and chymotrypsin genes
    • Walker, M. D., T. Edlund, A. M. Boulet, and W. J. Rutter. 1983. Cell-specific expression controlled by the 5' flanking regions of the insulin and chymotrypsin genes. Nature 306:557-581.
    • (1983) Nature , vol.306 , pp. 557-581
    • Walker, M.D.1    Edlund, T.2    Boulet, A.M.3    Rutter, W.J.4
  • 52
    • 0029909387 scopus 로고    scopus 로고
    • The human glucokinase gene beta-cell-type promoter: An essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells
    • Watada, H., Y. Kajimoto, Y. Umayahara, T. Matsuoka, H. Kaneto, Y. Fujitani, T. Kamada, R. Kawamori, and Y. Yamasaki. 1996. The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells. Diabetes 45:1478-1488.
    • (1996) Diabetes , vol.45 , pp. 1478-1488
    • Watada, H.1    Kajimoto, Y.2    Umayahara, Y.3    Matsuoka, T.4    Kaneto, H.5    Fujitani, Y.6    Kamada, T.7    Kawamori, R.8    Yamasaki, Y.9
  • 53
    • 0029811475 scopus 로고    scopus 로고
    • HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation
    • Zappavigna, V., L. Falciola, M. H. Citterich, F. Mavilio, and M. E. Bianchi. 1996. HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation. EMBO J. 15:4981-4991.
    • (1996) EMBO J. , vol.15 , pp. 4981-4991
    • Zappavigna, V.1    Falciola, L.2    Citterich, M.H.3    Mavilio, F.4    Bianchi, M.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.