-
1
-
-
73949133993
-
The molecular basis of the host response to lipopolysaccharide
-
Bryant CE, Spring DR, Gangloff M, Gay NJ. The molecular basis of the host response to lipopolysaccharide. Nat Rev Microbiol (2010) 8:8-14. doi:10.1038/nrmicro2266
-
(2010)
Nat Rev Microbiol
, vol.8
, pp. 8-14
-
-
Bryant, C.E.1
Spring, D.R.2
Gangloff, M.3
Gay, N.J.4
-
2
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in toll-like receptor signalling
-
O'Neill LA, Bowie AG. The family of five: TIR-domain-containing adaptors in toll-like receptor signalling. Nat Rev Immunol (2007) 7:353-64. doi:10.1038/nri2079
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
3
-
-
33746214788
-
A protein associated with toll-like receptor 4 (PRAT4A) regulates cell surface expression of TLR4
-
Wakabayashi Y, Kobayashi M, Akashi-Takamura S, Tanimura N, Konno K, Takahashi K, et al. A protein associated with toll-like receptor 4 (PRAT4A) regulates cell surface expression of TLR4. J Immunol (2006) 177:1772-9. doi:10.4049/jimmunol.177.3.1772
-
(2006)
J Immunol
, vol.177
, pp. 1772-1779
-
-
Wakabayashi, Y.1
Kobayashi, M.2
Akashi-Takamura, S.3
Tanimura, N.4
Konno, K.5
Takahashi, K.6
-
4
-
-
36549072863
-
A protein associated with toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses
-
Takahashi K, Shibata T, Akashi-Takamura S, Kiyokawa T, Wakabayashi Y, Tanimura N, et al. A protein associated with toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses. J Exp Med (2007) 204:2963-76. doi:10.1084/jem.20071132
-
(2007)
J Exp Med
, vol.204
, pp. 2963-2976
-
-
Takahashi, K.1
Shibata, T.2
Akashi-Takamura, S.3
Kiyokawa, T.4
Wakabayashi, Y.5
Tanimura, N.6
-
5
-
-
0034795208
-
Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability
-
Randow F, Seed B. Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability. Nat Cell Biol (2001) 3:891-6. doi:10.1038/ncb1001-891
-
(2001)
Nat Cell Biol
, vol.3
, pp. 891-896
-
-
Randow, F.1
Seed, B.2
-
6
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai Y, Akashi S, Nagafuku M, Ogata M, Iwakura Y, Akira S, et al. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat Immunol (2002) 3:667-72. doi:10.1038/ni809
-
(2002)
Nat Immunol
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
Akira, S.6
-
7
-
-
0037127309
-
MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor
-
Correia JD, Ulevitch RJ. MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor. J Biol Chem (2002) 277:1845-54. doi:10.1074/jbc.M109910200
-
(2002)
J Biol Chem
, vol.277
, pp. 1845-1854
-
-
Correia, J.D.1
Ulevitch, R.J.2
-
8
-
-
0037619127
-
MD-2 is necessary for the toll-like receptor 4 protein to undergo glycosylation essential for its translocation to the cell surface
-
Ohnishi T, Muroi M, Tanamoto K. MD-2 is necessary for the toll-like receptor 4 protein to undergo glycosylation essential for its translocation to the cell surface. Clin Diagn Lab Immunol (2003) 10:405-10. doi:10.1128/CDLI.10.3.405-410.2003
-
(2003)
Clin Diagn Lab Immunol
, vol.10
, pp. 405-410
-
-
Ohnishi, T.1
Muroi, M.2
Tanamoto, K.3
-
9
-
-
1642529500
-
Isolation of an endotoxin-MD-2 complex that produces toll-like receptor 4-dependent cell activation at picomolar concentrations
-
Gioannini TL, Teghanemt A, Zhang D, Coussens NP, Dockstader W, Ramaswamy S, et al. Isolation of an endotoxin-MD-2 complex that produces toll-like receptor 4-dependent cell activation at picomolar concentrations. Proc Natl Acad Sci U S A (2004) 101:4186-91. doi:10.1073/pnas.0306906101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 4186-4191
-
-
Gioannini, T.L.1
Teghanemt, A.2
Zhang, D.3
Coussens, N.P.4
Dockstader, W.5
Ramaswamy, S.6
-
10
-
-
81055129630
-
CD14 controls the LPS-induced endocytosis of toll-like receptor 4
-
Zanoni I, Ostuni R, Marek LR, Barresi S, Barbalat R, Barton GM, et al. CD14 controls the LPS-induced endocytosis of toll-like receptor 4. Cell (2011) 147:868-80. doi:10.1016/j.cell.2011.09.051
-
(2011)
Cell
, vol.147
, pp. 868-880
-
-
Zanoni, I.1
Ostuni, R.2
Marek, L.R.3
Barresi, S.4
Barbalat, R.5
Barton, G.M.6
-
11
-
-
0025166114
-
Cd14, a receptor for complexes of lipopolysaccharide (Lps) and Lps binding-protein
-
Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC. Cd14, a receptor for complexes of lipopolysaccharide (Lps) and Lps binding-protein. Science (1990) 249:1431-3. doi:10.1126/science.1698311
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
12
-
-
0034292364
-
Cutting edge: lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B
-
Jiang QQ, Akashi S, Miyake K, Petty HR. Cutting edge: lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. J Immunol (2000) 165:3541-4. doi:10.4049/jimmunol.165.7.3541
-
(2000)
J Immunol
, vol.165
, pp. 3541-3544
-
-
Jiang, Q.Q.1
Akashi, S.2
Miyake, K.3
Petty, H.R.4
-
13
-
-
84918825642
-
The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membrane
-
Liaunardy-Jopeace A, Bryant CE, Gay NJ. The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membrane. Sci Signal (2014) 7:ra70. doi:10.1126/scisignal.2005275
-
(2014)
Sci Signal
, vol.7
-
-
Liaunardy-Jopeace, A.1
Bryant, C.E.2
Gay, N.J.3
-
14
-
-
84857726793
-
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation
-
Doyle SL, Husebye H, Connolly DJ, Espevik T, O'Neill LA, McGettrick AF. The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nat Commun (2012) 3:707. doi:10.1038/ncomms1706
-
(2012)
Nat Commun
, vol.3
, pp. 707
-
-
Doyle, S.L.1
Husebye, H.2
Connolly, D.J.3
Espevik, T.4
O'Neill, L.A.5
McGettrick, A.F.6
-
15
-
-
77956358594
-
Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane
-
Wang D, Lou J, Ouyang C, Chen W, Liu Y, Liu X, et al. Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane. Proc Natl Acad Sci U S A (2010) 107:13806-11. doi:10.1073/pnas.1009428107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 13806-13811
-
-
Wang, D.1
Lou, J.2
Ouyang, C.3
Chen, W.4
Liu, Y.5
Liu, X.6
-
16
-
-
77958487596
-
The Rab11a GTPase controls toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
-
Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, et al. The Rab11a GTPase controls toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes. Immunity (2010) 33:583-96. doi:10.1016/j.immuni.2010.09.010
-
(2010)
Immunity
, vol.33
, pp. 583-596
-
-
Husebye, H.1
Aune, M.H.2
Stenvik, J.3
Samstad, E.4
Skjeldal, F.5
Halaas, O.6
-
17
-
-
34547953017
-
Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4
-
Wang Y, Chen T, Han C, He D, Liu H, An H, et al. Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Blood (2007) 110:962-71. doi:10.1182/blood-2007-01-066027
-
(2007)
Blood
, vol.110
, pp. 962-971
-
-
Wang, Y.1
Chen, T.2
Han, C.3
He, D.4
Liu, H.5
An, H.6
-
18
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio M, Ni J, Feng P, Dixit VM. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science (1997) 278:1612-5. doi:10.1126/science.278.5343.1612
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
19
-
-
0031423761
-
MyD88: an adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche H, Henzel WJ, Shillinglaw W, Li S, Cao ZD. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity (1997) 7:837-47. doi:10.1016/S1074-7613(00)80402-1
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.D.5
-
20
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity (1999) 11:115-22. doi:10.1016/S1074-7613(00)80086-2
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
21
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for toll-like receptor-4 signal transduction
-
Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, et al. Mal (MyD88-adapter-like) is required for toll-like receptor-4 signal transduction. Nature (2001) 413:78-83. doi:10.1038/35092578
-
(2001)
Nature
, vol.413
, pp. 78-83
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
-
22
-
-
0035555301
-
TIRAP: an adapter molecule in the toll signaling pathway
-
Horng T, Barton GM, Medzhitov R. TIRAP: an adapter molecule in the toll signaling pathway. Nat Immunol (2001) 2:835-41. doi:10.1038/ni0901-835
-
(2001)
Nat Immunol
, vol.2
, pp. 835-841
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
23
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science (2003) 301:640-3. doi:10.1126/science.1087262
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
-
24
-
-
0037114185
-
Cutting edge: a novel toll/IL-1 receptor Domain containing adapter that preferentially activates the IFN-beta promoter in the toll-like receptor signaling
-
Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K, et al. Cutting edge: a novel toll/IL-1 receptor Domain containing adapter that preferentially activates the IFN-beta promoter in the toll-like receptor signaling. J Immunol (2002) 169:6668-72. doi:10.4049/jimmunol.169.12.6668
-
(2002)
J Immunol
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
-
25
-
-
0042591216
-
TIRP, a novel toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling
-
Bin LH, Xu LG, Shu HB. TIRP, a novel toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. J Biol Chem (2003) 278:24526-32. doi:10.1074/jbc.M303451200
-
(2003)
J Biol Chem
, vol.278
, pp. 24526-24532
-
-
Bin, L.H.1
Xu, L.G.2
Shu, H.B.3
-
26
-
-
0242624622
-
TRAM is specifically involved in the toll-like receptor 4-mediated MyD88- independent signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Uematsu S, Hoshino K, Kaisho T, et al. TRAM is specifically involved in the toll-like receptor 4-mediated MyD88- independent signaling pathway. Nat Immunol (2003) 4:1144-50. doi:10.1038/ni986
-
(2003)
Nat Immunol
, vol.4
, pp. 1144-1150
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Uematsu, S.4
Hoshino, K.5
Kaisho, T.6
-
27
-
-
33748871187
-
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent toll-like receptor signaling
-
Carty M, Goodbody R, Schroder M, Stack J, Moynagh PN, Bowie AG. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent toll-like receptor signaling. Nat Immunol (2006) 7:1074-81. doi:10.1038/ni1382
-
(2006)
Nat Immunol
, vol.7
, pp. 1074-1081
-
-
Carty, M.1
Goodbody, R.2
Schroder, M.3
Stack, J.4
Moynagh, P.N.5
Bowie, A.G.6
-
28
-
-
77953315434
-
SARM inhibits both TRIF- and MyD88-mediated AP-1 activation
-
Peng J, Yuan Q, Lin B, Panneerselvam P, Wang X, Luan XL, et al. SARM inhibits both TRIF- and MyD88-mediated AP-1 activation. Eur J Immunol (2010) 40:1738-47. doi:10.1002/eji.200940034
-
(2010)
Eur J Immunol
, vol.40
, pp. 1738-1747
-
-
Peng, J.1
Yuan, Q.2
Lin, B.3
Panneerselvam, P.4
Wang, X.5
Luan, X.L.6
-
29
-
-
0035367786
-
A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans
-
Mink M, Fogelgren B, Olszewski K, Maroy P, Csiszar K. A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics (2001) 74:234-44. doi:10.1006/geno.2001.6548
-
(2001)
Genomics
, vol.74
, pp. 234-244
-
-
Mink, M.1
Fogelgren, B.2
Olszewski, K.3
Maroy, P.4
Csiszar, K.5
-
30
-
-
84892714228
-
Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages
-
Ling GS, Bennett J, Woollard KJ, Szajna M, Fossati-Jimack L, Taylor PR, et al. Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages. Nat Commun (2014) 5:3039. doi:10.1038/ncomms4039
-
(2014)
Nat Commun
, vol.5
, pp. 3039
-
-
Ling, G.S.1
Bennett, J.2
Woollard, K.J.3
Szajna, M.4
Fossati-Jimack, L.5
Taylor, P.R.6
-
31
-
-
84856745386
-
Phospholipase Cgamma-2 and intracellular calcium are required for lipopolysaccharide-induced toll-like receptor 4 (TLR4) endocytosis and interferon regulatory factor 3 (IRF3) activation
-
Chiang CY, Veckman V, Limmer K, David M. Phospholipase Cgamma-2 and intracellular calcium are required for lipopolysaccharide-induced toll-like receptor 4 (TLR4) endocytosis and interferon regulatory factor 3 (IRF3) activation. J Biol Chem (2012) 287:3704-9. doi:10.1074/jbc.C111.328559
-
(2012)
J Biol Chem
, vol.287
, pp. 3704-3709
-
-
Chiang, C.Y.1
Veckman, V.2
Limmer, K.3
David, M.4
-
32
-
-
0142157000
-
Intracellular recognition of lipopolysaccharide by toll-like receptor 4 in intestinal epithelial cells
-
Hornef MW, Normark BH, Vandewalle A, Normark S. Intracellular recognition of lipopolysaccharide by toll-like receptor 4 in intestinal epithelial cells. J Exp Med (2003) 198:1225-35. doi:10.1084/jem.20022194
-
(2003)
J Exp Med
, vol.198
, pp. 1225-1235
-
-
Hornef, M.W.1
Normark, B.H.2
Vandewalle, A.3
Normark, S.4
-
33
-
-
68649089025
-
Chaperones and transport proteins regulate TLR4 trafficking and activation
-
Saitoh S. Chaperones and transport proteins regulate TLR4 trafficking and activation. Immunobiology (2009) 214:594-600. doi:10.1016/j.imbio.2008.11.012
-
(2009)
Immunobiology
, vol.214
, pp. 594-600
-
-
Saitoh, S.1
-
34
-
-
70349855203
-
Glycoprotein folding, quality control and ER-associated degradation
-
Lederkremer GZ. Glycoprotein folding, quality control and ER-associated degradation. Curr Opin Struct Biol (2009) 19:515-23. doi:10.1016/j.sbi.2009.06.004
-
(2009)
Curr Opin Struct Biol
, vol.19
, pp. 515-523
-
-
Lederkremer, G.Z.1
-
35
-
-
84878253184
-
Organization of the ER-Golgi interface for membrane traffic control
-
Brandizzi F, Barlowe C. Organization of the ER-Golgi interface for membrane traffic control. Nat Rev Mol Cell Biol (2013) 14:382-92. doi:10.1038/nrm3588
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 382-392
-
-
Brandizzi, F.1
Barlowe, C.2
-
36
-
-
70149084008
-
The p24 family and selective transport processes at the ER-Golgi interface
-
Strating JR, Martens GJ. The p24 family and selective transport processes at the ER-Golgi interface. Biol Cell (2009) 101:495-509. doi:10.1042/BC20080233
-
(2009)
Biol Cell
, vol.101
, pp. 495-509
-
-
Strating, J.R.1
Martens, G.J.2
-
37
-
-
67749120450
-
A comprehensive overview of the vertebrate p24 family: identification of a novel tissue-specifically expressed member
-
Strating JR, van Bakel NH, Leunissen JA, Martens GJ. A comprehensive overview of the vertebrate p24 family: identification of a novel tissue-specifically expressed member. Mol Biol Evol (2009) 26:1707-14. doi:10.1093/molbev/msp099
-
(2009)
Mol Biol Evol
, vol.26
, pp. 1707-1714
-
-
Strating, J.R.1
van Bakel, N.H.2
Leunissen, J.A.3
Martens, G.J.4
-
38
-
-
0028964475
-
The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi
-
Schimmoller F, Singer-Kruger B, Schroder S, Kruger U, Barlowe C, Riezman H. The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi. EMBO J (1995) 14:1329-39.
-
(1995)
EMBO J
, vol.14
, pp. 1329-1339
-
-
Schimmoller, F.1
Singer-Kruger, B.2
Schroder, S.3
Kruger, U.4
Barlowe, C.5
Riezman, H.6
-
39
-
-
0034033881
-
The transmembrane protein p23 contributes to the organization of the Golgi apparatus
-
Rojo M, Emery G, Marjomaki V, McDowall AW, Parton RG, Gruenberg J. The transmembrane protein p23 contributes to the organization of the Golgi apparatus. J Cell Sci (2000) 113(Pt 6):1043-57.
-
(2000)
J Cell Sci
, vol.113
, Issue.6 PART
, pp. 1043-1057
-
-
Rojo, M.1
Emery, G.2
Marjomaki, V.3
McDowall, A.W.4
Parton, R.G.5
Gruenberg, J.6
-
40
-
-
0033965985
-
The p24 family member p23 is required for early embryonic development
-
Denzel A, Otto F, Girod A, Pepperkok R, Watson R, Rosewell I, et al. The p24 family member p23 is required for early embryonic development. Curr Biol (2000) 10:55-8. doi:10.1016/S0960-9822(99)00266-3
-
(2000)
Curr Biol
, vol.10
, pp. 55-58
-
-
Denzel, A.1
Otto, F.2
Girod, A.3
Pepperkok, R.4
Watson, R.5
Rosewell, I.6
-
41
-
-
0030015550
-
Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations
-
Elrod-Erickson MJ, Kaiser CA. Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations. Mol Biol Cell (1996) 7:1043-58. doi:10.1091/mbc.7.7.1043
-
(1996)
Mol Biol Cell
, vol.7
, pp. 1043-1058
-
-
Elrod-Erickson, M.J.1
Kaiser, C.A.2
-
42
-
-
0035159694
-
Deletion of yeast p24 genes activates the unfolded protein response
-
Belden WJ, Barlowe C. Deletion of yeast p24 genes activates the unfolded protein response. Mol Biol Cell (2001) 12:957-69. doi:10.1091/mbc.12.4.957
-
(2001)
Mol Biol Cell
, vol.12
, pp. 957-969
-
-
Belden, W.J.1
Barlowe, C.2
-
43
-
-
77951249789
-
The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta
-
Jerome-Majewska LA, Achkar T, Luo L, Lupu F, Lacy E. The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta. Dev Biol (2010) 341:154-66. doi:10.1016/j.ydbio.2010.02.019
-
(2010)
Dev Biol
, vol.341
, pp. 154-166
-
-
Jerome-Majewska, L.A.1
Achkar, T.2
Luo, L.3
Lupu, F.4
Lacy, E.5
-
44
-
-
84879071925
-
Rab10 delivers GLUT4 storage vesicles to the plasma membrane
-
Chen Y, Lippincott-Schwartz J. Rab10 delivers GLUT4 storage vesicles to the plasma membrane. Commun Integr Biol (2013) 6:e23779. doi:10.4161/cib.23779
-
(2013)
Commun Integr Biol
, vol.6
-
-
Chen, Y.1
Lippincott-Schwartz, J.2
-
45
-
-
35648992037
-
p24A, a type I transmembrane protein, controls ARF1-dependent resensitization of protease-activated receptor-2 by influence on receptor trafficking
-
Luo W, Wang Y, Reiser G. p24A, a type I transmembrane protein, controls ARF1-dependent resensitization of protease-activated receptor-2 by influence on receptor trafficking. J Biol Chem (2007) 282:30246-55. doi:10.1074/jbc.M703205200
-
(2007)
J Biol Chem
, vol.282
, pp. 30246-30255
-
-
Luo, W.1
Wang, Y.2
Reiser, G.3
-
46
-
-
84886398358
-
Anti-CD14 antibody reduces LPS responsiveness via TLR4 internalization in human monocytes
-
Kim D, Kim JY. Anti-CD14 antibody reduces LPS responsiveness via TLR4 internalization in human monocytes. Mol Immunol (2014) 57:210-5. doi:10.1016/j.molimm.2013.09.009
-
(2014)
Mol Immunol
, vol.57
, pp. 210-215
-
-
Kim, D.1
Kim, J.Y.2
-
47
-
-
77956942676
-
Carbon monoxide suppresses membrane expression of TLR4 via myeloid differentiation factor-2 in betaTC3 cells
-
Rocuts F, Ma Y, Zhang X, Gao W, Yue Y, Vartanian T, et al. Carbon monoxide suppresses membrane expression of TLR4 via myeloid differentiation factor-2 in betaTC3 cells. J Immunol (2010) 185:2134-9. doi:10.4049/jimmunol.0902782
-
(2010)
J Immunol
, vol.185
, pp. 2134-2139
-
-
Rocuts, F.1
Ma, Y.2
Zhang, X.3
Gao, W.4
Yue, Y.5
Vartanian, T.6
-
48
-
-
33644508366
-
Endocytic pathways regulate toll-like receptor 4 signaling and link innate and adaptive immunity
-
Husebye H, Halaas O, Stenmark H, Tunheim G, Sandanger O, Bogen B, et al. Endocytic pathways regulate toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO J (2006) 25:683-92. doi:10.1038/sj.emboj.7600991
-
(2006)
EMBO J
, vol.25
, pp. 683-692
-
-
Husebye, H.1
Halaas, O.2
Stenmark, H.3
Tunheim, G.4
Sandanger, O.5
Bogen, B.6
-
49
-
-
40949134086
-
TRAM couples endocytosis of toll-like receptor 4 to the induction of interferon-beta
-
Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R. TRAM couples endocytosis of toll-like receptor 4 to the induction of interferon-beta. Nat Immunol (2008) 9:361-8. doi:10.1038/ni1569
-
(2008)
Nat Immunol
, vol.9
, pp. 361-368
-
-
Kagan, J.C.1
Su, T.2
Horng, T.3
Chow, A.4
Akira, S.5
Medzhitov, R.6
-
50
-
-
67649422321
-
Therapeutic targeting of toll-like receptors for infectious and inflammatory diseases and cancer
-
O'Neill LA, Bryant CE, Doyle SL. Therapeutic targeting of toll-like receptors for infectious and inflammatory diseases and cancer. Pharmacol Rev (2009) 61:177-97. doi:10.1124/pr.109.001073
-
(2009)
Pharmacol Rev
, vol.61
, pp. 177-197
-
-
O'Neill, L.A.1
Bryant, C.E.2
Doyle, S.L.3
-
51
-
-
77955886553
-
Crucial role for human toll-like receptor 4 in the development of contact allergy to nickel
-
Schmidt M, Raghavan B, Muller V, Vogl T, Fejer G, Tchaptchet S, et al. Crucial role for human toll-like receptor 4 in the development of contact allergy to nickel. Nat Immunol (2010) 11:814-9. doi:10.1038/ni.1919
-
(2010)
Nat Immunol
, vol.11
, pp. 814-819
-
-
Schmidt, M.1
Raghavan, B.2
Muller, V.3
Vogl, T.4
Fejer, G.5
Tchaptchet, S.6
-
52
-
-
84896737910
-
Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions
-
Resman N, Oblak A, Gioannini TL, Weiss JP, Jerala R. Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions. J Immunol (2014) 192:1887-95. doi:10.4049/jimmunol.1302119
-
(2014)
J Immunol
, vol.192
, pp. 1887-1895
-
-
Resman, N.1
Oblak, A.2
Gioannini, T.L.3
Weiss, J.P.4
Jerala, R.5
-
53
-
-
84881408201
-
Allergens as immunomodulatory proteins: the cat dander protein Fel d 1 enhances TLR activation by lipid ligands
-
Herre J, Gronlund H, Brooks H, Hopkins L, Waggoner L, Murton B, et al. Allergens as immunomodulatory proteins: the cat dander protein Fel d 1 enhances TLR activation by lipid ligands. J Immunol (2013) 191:1529-35. doi:10.4049/jimmunol.1300284
-
(2013)
J Immunol
, vol.191
, pp. 1529-1535
-
-
Herre, J.1
Gronlund, H.2
Brooks, H.3
Hopkins, L.4
Waggoner, L.5
Murton, B.6
-
54
-
-
84869880290
-
High-mobility group box family of proteins: ligand and sensor for innate immunity
-
Yanai H, Ban T, Taniguchi T. High-mobility group box family of proteins: ligand and sensor for innate immunity. Trends Immunol (2012) 33:633-40. doi:10.1016/j.it.2012.10.005
-
(2012)
Trends Immunol
, vol.33
, pp. 633-640
-
-
Yanai, H.1
Ban, T.2
Taniguchi, T.3
-
55
-
-
23644456849
-
The matrix component biglycan is proinflammatory and signals through toll-like receptors 4 and 2 in macrophages
-
Schaefer L, Babelova A, Kiss E, Hausser HJ, Baliova M, Krzyzankova M, et al. The matrix component biglycan is proinflammatory and signals through toll-like receptors 4 and 2 in macrophages. J Clin Inv (2005) 115:2223-33. doi:10.1172/JCI23755
-
(2005)
J Clin Inv
, vol.115
, pp. 2223-2233
-
-
Schaefer, L.1
Babelova, A.2
Kiss, E.3
Hausser, H.J.4
Baliova, M.5
Krzyzankova, M.6
-
56
-
-
67650502739
-
Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease
-
Midwood K, Sacre S, Piccinini AM, Inglis J, Trebaul A, Chan E, et al. Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease. Nat Med (2009) 15:774-80. doi:10.1038/nm.1987
-
(2009)
Nat Med
, vol.15
, pp. 774-780
-
-
Midwood, K.1
Sacre, S.2
Piccinini, A.M.3
Inglis, J.4
Trebaul, A.5
Chan, E.6
-
57
-
-
34948900275
-
Mrp8 and Mrp14 are endogenous activators of toll-like receptor 4, promoting lethal, endotoxin-induced shock
-
Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, et al. Mrp8 and Mrp14 are endogenous activators of toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat Med (2007) 13:1042-9. doi:10.1038/nm1638
-
(2007)
Nat Med
, vol.13
, pp. 1042-1049
-
-
Vogl, T.1
Tenbrock, K.2
Ludwig, S.3
Leukert, N.4
Ehrhardt, C.5
van Zoelen, M.A.6
-
58
-
-
67349182481
-
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
-
Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature (2009) 458:1191-5. doi:10.1038/nature07830
-
(2009)
Nature
, vol.458
, pp. 1191-1195
-
-
Park, B.S.1
Song, D.H.2
Kim, H.M.3
Choi, B.S.4
Lee, H.5
Lee, J.O.6
-
59
-
-
77950591965
-
MD-2-mediated ionic interactions between lipid A and TLR4 are essential for receptor activation
-
Meng J, Lien E, Golenbock DT. MD-2-mediated ionic interactions between lipid A and TLR4 are essential for receptor activation. J Biol Chem (2009) 285(12):8695-702. doi:10.1074/jbc.M109.075127
-
(2009)
J Biol Chem
, vol.285
, Issue.12
, pp. 8695-8702
-
-
Meng, J.1
Lien, E.2
Golenbock, D.T.3
-
60
-
-
84870576417
-
Metal allergens nickel and cobalt facilitate TLR4 homodimerization independently of MD2
-
Raghavan B, Martin SF, Esser PR, Goebeler M, Schmidt M. Metal allergens nickel and cobalt facilitate TLR4 homodimerization independently of MD2. EMBO Rep (2012) 13:1109-15. doi:10.1038/embor.2012.155
-
(2012)
EMBO Rep
, vol.13
, pp. 1109-1115
-
-
Raghavan, B.1
Martin, S.F.2
Esser, P.R.3
Goebeler, M.4
Schmidt, M.5
-
61
-
-
4143150809
-
The myeloid expressed EF-hand proteins display a diverse pattern of lipid raft association
-
Nacken W, Sorg C, Kerkhoff C. The myeloid expressed EF-hand proteins display a diverse pattern of lipid raft association. FEBS Lett (2004) 572:289-93. doi:10.1016/j.febslet.2004.07.024
-
(2004)
FEBS Lett
, vol.572
, pp. 289-293
-
-
Nacken, W.1
Sorg, C.2
Kerkhoff, C.3
-
62
-
-
84892647719
-
PIP(3) induces the recycling of receptor tyrosine kinases
-
Laketa V, Zarbakhsh S, Traynor-Kaplan A, Macnamara A, Subramanian D, Putyrski M, et al. PIP(3) induces the recycling of receptor tyrosine kinases. Sci Signal (2014) 7:ra5. doi:10.1126/scisignal.2004532
-
(2014)
Sci Signal
, vol.7
-
-
Laketa, V.1
Zarbakhsh, S.2
Traynor-Kaplan, A.3
Macnamara, A.4
Subramanian, D.5
Putyrski, M.6
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