Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations

Molecular Biology of the Cell

Volumn 7, Issue 7, 1996, Pages 1043-1058

  Elrod Erickson, Matthew J ^a   Kaiser, Chris A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA FRUCTOFURANOSIDASE; MEMBRANE PROTEIN; MUTANT PROTEIN; SECRETORY PROTEIN; SERINE CARBOXYPEPTIDASE;

ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE MUTATION; GOLGI COMPLEX; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE;

EID: 0030015550     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.7.7.1043     Document Type: Article

References (48)

1. Balch, W.E., McCaffery, J.M., Plutner, H., and Farquhar, M.G. (1994). Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum. Cell 76, 841-852.
2. Barlowe, C., Orci, L., Yeung, T., Hosobuchi, M., Hamamoto, S., Salama, N., Rexach, M.F., Ravazzola, M., Amherdt, M., and Schekman, R. (1994). COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 77, 895-907.
3. Bednarek, S.Y., Ravazzola, M., Hosobuchi, M., Amherdt, M., Perrelet, A., Schekman, R., and Orci, L. (1995). COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. Cell 83, 1183-1196.
4. Boehm, J., Ulrich, H.D., Ossig, R., and Schmitt, H.D. (1994). Kex2-dependent invertase secretion as a tool to study the targeting of transmembrane proteins which are involved in ER >Golgi transport in yeast. EMBO J. 13, 3696-3710.
5. Bohni, P.C., Schauer, I., Tekamp-Olson, P., and Schekman, R. (1987). Signal peptide cleavage mutants of yeast invertase. In: Proteases in Biological Control and Technology. New York: Alan R. Liss, Inc. 255-264.
6. d'Enfert, C., Barlowe, C., Nishikawa, S.-I., Nakano, A., and Schekman, R. (1991). Structural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulum. Mol. Cell. Biol. 11, 5727-5734.
7. Deshaies, R.J., and Schekman, R. (1990). Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery. Mol. Cell. Biol. 10, 6024-6035.
8. Espenshade, P., Gimeno, R.E., Holzmacher, E., Teung, P., and Kaiser, C.A. (1995). Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p. J. Cell Biol. 131, 311-324.
9. Gascón, S., Neumann, N.P., and Lampen, J.O. (1968). Comparative study of the properties of the purified internal and external invertases from yeast. J. Biol. Chem. 243, 1573-1577.
10. Gaynor, E.C., te Heesen, S., Graham, T.R., Aebi, M., and Emr, S.D. (1994). Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast. J. Cell Biol. 127, 653-665.
11. Gimeno, R.E., Espenshade, P., and Kaiser, C.A. (1995). SED4 encodes a yeast endoplasmic reticulum protein that binds Sec16p and participates in vesicle formation. J. Cell Biol. 131, 325-338.
12. Hardwick, K.G., Lewis, M.J., Semenza, J., Dean, N., and Pelham, H.R.B. (1990). ERD1, a yeast gene required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus. EMBO J. 9, 623-630.
13. Henikoff, S. (1984). Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. Gene 28, 351-359.
14. Hicke, L., Yoshihisa, T., and Schekman, R. (1992). Sec23p and a novel 105-kDa protein function as a multimeric complex to promote vesicle budding and protein transport from the endoplasmic reticulum. Mol. Biol. Cell 3, 667-676.
15. Kaiser, C., Michaelis, S., and Mitchell, A. (1994). Methods in Yeast Genetics, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
16. Kaiser, C.A., and Schekman, R. (1990). Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway. Cell 61, 723-733.
17. Kolodziej, P.A., and Young, R.A. (1991). Epitope tagging and protein surveillance. Methods Enzymol. 194, 508-519.
18. Kunkel, T.A., Roberts, J.D., and Zakour, R.A. (1987). Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol. 154, 367-382.
19. Kyte, J., and Doolittle, R.F. (1982). A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157, 105-132.
20. LaMantia, M., and Lennarz, W.J. (1993). The essential function of yeast protein disulfide isomerase does not reside in its isomerase activity. Cell 74, 899-908.
21. Letourner, F., Gaynor, E.C., Hennecke, S., Démollière, C., Dunden, R., Emr, S.D., Riezman, H., and Cosson, P. (1994). Coatamer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum. Cell 79, 1199-1207.
22. Mizuno, M., and Singer, S.J. (1993). A soluble secretory protein is first concentrated in the endoplasmic reticulum before transfer to the Golgi apparatus. Proc. Natl. Acad. Sci. USA 90, 5732-5736.
23. Nakano, A., Brada, D., and Schekman, R. (1988). A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast. J. Cell Biol. 107, 851-863.
24. Nakano, A., and Muramatsu, M. (1989). A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus. J. Cell Biol. 109, 2677-2691.
25. Nilsson, T., Jackson, M., and Peterson, P.A. (1989). Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum. Cell 58, 707-718.
26. Nishikawa, S.-I., and Nakano, A. (1993). Identification of a gene required for membrane protein retention in the early secretory pathway. Proc. Natl. Acad. Sci. USA 90, 8179-8183.
27. Oka, R., Nishikawa, S.-I., and Nakano, A. (1991). Reconstitution of GTP-binding Sar1 protein function in ER to Golgi transport. J. Cell Biol. 114, 671-679.
28. Orci, L., Ravazzola, M., Meda, P., Holcomb, C., Moore, H.-P., Hicke, L., and Schekman, R. (1991). Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm. Proc. Natl. Acad. Sci. USA 88, 8611-8615.
29. Palade, G. (1975). Intracellular aspects of the process of protein synthesis. Science 189, 347-358.
30. Parlati, F., Dominguez, M., Bergeron, J.J.M., and Thomas, D.Y. (1995). Saccharomyces cerevisiae CNE1 encodes an endoplasmic reticulum (ER) membrane protein with sequence similarity to calnexin and calreticulin and functions as a constituent of the ER quality control apparatus. J. Biol. Chem. 270, 244-253.
31. Pearse, B.M.F., and Robinson, M.S. (1990). Clathrin, adaptors, and sorting. Annu. Rev. Cell Biol. 6, 151-171.
32. Pelham, H.R.B. (1995). Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus. Curr. Opin. Cell Biol. 7, 530-535.
33. Pfeffer, S.R., and Rothman, J.E. (1987). Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi. Annu. Rev. Biochem. 56, 829-852.
34. Pryer, N.K., Salama, N.R., Schekman, R., and Kaiser, C.A. (1993). Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro. J. Cell Biol. 120, 865-875.
35. Pryer, N.K., Wuestehube, L.J., and Schekman, R. (1992). Vesicle-mediated protein sorting. Annu. Rev. Biochem. 61, 471-516.
36. Rose, M.D., Misra, L.M., and Vogel, J.P. (1989). KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene. Cell 57, 1211-1221.
37. Rose, M.D., Novick, P., Thomas, J.H., Botstein, D., and Fink, G.R. (1987). A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene 60, 237-243.
38. Rothman, J.E., and Orci, L. (1992). Molecular dissection of the secretory pathway. Nature 355, 409-415.
39. Salama, N.R., Yeung, T., and Schekman, R.W. (1993). The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins. EMBO J. 12, 4073-4082.
40. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
41. Schimmöller, F., Singer-Krüger, B., Schröder, S., Krüger, U., Barlowe, C., and Riezman, H. (1995). The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi. EMBO J. 14, 1329-1339.
42. Schutze, M.-P., Peterson, P.A., and Jackson, M.R. (1994). An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum. EMBO J. 13, 1696-1705.
43. Semenza, J., Hardwick, K., Dean, N., and Pelham, H. (1990). ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway. Cell 61, 1349-1357.
44. Shaywitz, D.A., Orci, L., and Kaiser, C.A. (1995). Human SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulum. J. Cell Biol. 128, 769-777.
45. Sikorski, R.S., and Hieter, P. (1989). A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122, 19-27.
46. Stamnes, M.A., Craighead, M.W., Hoe, M.H., Lampen, N., Geromanos, S., Tempst, P., and Rothman, J.E. (1995). An integral membrane component of coatamer-coated transport vesicles defines a family of proteins involved in budding. Proc. Natl Acad. Sci. USA 92, 8011-8015.
47. Stevens, T., Esmon, B., and Schekman, R. (1982). Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole. Cell 30, 439-448.
48. Tyers, M., Tokiwa, G., and Futcher, B. (1993). Comparison of the Saccharomyces cerivisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2, and other cyclins. EMBO J. 12, 1955-1968.