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Volumn 23, Issue 1, 2015, Pages 22-30

Metabolic triggered inflammation in osteoarthritis

Author keywords

Inflammation; Metabolic factors; Obesity; Osteoarthritis

Indexed keywords

ADALIMUMAB; ADIPOCYTOKINE; ADIPONECTIN; AMG 108; ANTILIPEMIC AGENT; C REACTIVE PROTEIN; CYTOKINE; DIACEREIN; LEPTIN; MICRORNA; MONOCLONAL ANTIBODY; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; VITAMIN D;

EID: 84918821685     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2014.10.002     Document Type: Review
Times cited : (209)

References (105)
  • 1
    • 31044436046 scopus 로고    scopus 로고
    • Projections of US prevalence of arthritis and associated activity limitations
    • Hootman J.M., Helmick C.G. Projections of US prevalence of arthritis and associated activity limitations. Arthritis Rheum 2006, 54(1):226-229.
    • (2006) Arthritis Rheum , vol.54 , Issue.1 , pp. 226-229
    • Hootman, J.M.1    Helmick, C.G.2
  • 2
    • 72149116709 scopus 로고    scopus 로고
    • Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis
    • Blagojevic M., Jinks C., Jeffery A., Jordan K.P. Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis. Osteoarthritis Cartilage 2010, 18(1):24-33.
    • (2010) Osteoarthritis Cartilage , vol.18 , Issue.1 , pp. 24-33
    • Blagojevic, M.1    Jinks, C.2    Jeffery, A.3    Jordan, K.P.4
  • 3
    • 84870696930 scopus 로고    scopus 로고
    • Metabolic syndrome meets osteoarthritis
    • Zhuo Q., Yang W., Chen J., Wang Y. Metabolic syndrome meets osteoarthritis. Nat Rev Rheumatol 2012, 8(12):729-737.
    • (2012) Nat Rev Rheumatol , vol.8 , Issue.12 , pp. 729-737
    • Zhuo, Q.1    Yang, W.2    Chen, J.3    Wang, Y.4
  • 5
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444(7121):860-867.
    • (2006) Nature , vol.444 , Issue.7121 , pp. 860-867
    • Hotamisligil, G.S.1
  • 6
    • 77955362775 scopus 로고    scopus 로고
    • Chronic inflammation in obesity and the metabolic syndrome
    • Monteiro R., Azevedo I. Chronic inflammation in obesity and the metabolic syndrome. Mediators Inflamm 2010, 2010.
    • (2010) Mediators Inflamm , vol.2010
    • Monteiro, R.1    Azevedo, I.2
  • 7
    • 79151484704 scopus 로고    scopus 로고
    • Adipokines in inflammation and metabolic disease
    • Ouchi N., Parker J.L., Lugus J.J., Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol 2011, 11(2):85-97.
    • (2011) Nat Rev Immunol , vol.11 , Issue.2 , pp. 85-97
    • Ouchi, N.1    Parker, J.L.2    Lugus, J.J.3    Walsh, K.4
  • 9
    • 34548354722 scopus 로고    scopus 로고
    • Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
    • Zeyda M., Farmer D., Todoric J., Aszmann O., Speiser M., Gyori G., et al. Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int J Obes 2007, 31(9):1420-1428.
    • (2007) Int J Obes , vol.31 , Issue.9 , pp. 1420-1428
    • Zeyda, M.1    Farmer, D.2    Todoric, J.3    Aszmann, O.4    Speiser, M.5    Gyori, G.6
  • 10
    • 0033545342 scopus 로고    scopus 로고
    • Acute-phase proteins and other systemic responses to inflammation
    • Epstein F.H., Gabay C., Kushner I. Acute-phase proteins and other systemic responses to inflammation. NEngl J Med 1999, 340(6):448-454.
    • (1999) NEngl J Med , vol.340 , Issue.6 , pp. 448-454
    • Epstein, F.H.1    Gabay, C.2    Kushner, I.3
  • 11
  • 12
    • 77958523146 scopus 로고    scopus 로고
    • Not a simple fat-soluble vitamin: changes in serum 25-(OH)D levels are predicted by adiposity and adipocytokines in older adults
    • Ding C., Parameswaran V., Blizzard L., Burgess J., Jones G. Not a simple fat-soluble vitamin: changes in serum 25-(OH)D levels are predicted by adiposity and adipocytokines in older adults. JIntern Med 2010, 268(5):501-510.
    • (2010) JIntern Med , vol.268 , Issue.5 , pp. 501-510
    • Ding, C.1    Parameswaran, V.2    Blizzard, L.3    Burgess, J.4    Jones, G.5
  • 13
    • 65549144017 scopus 로고    scopus 로고
    • MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity
    • Xie H., Lim B., Lodish H.F. MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes 2009, 58(5):1050-1057.
    • (2009) Diabetes , vol.58 , Issue.5 , pp. 1050-1057
    • Xie, H.1    Lim, B.2    Lodish, H.F.3
  • 14
    • 50249134930 scopus 로고    scopus 로고
    • Association between leptin, body composition, sex and knee cartilage morphology in older adults: the Tasmanian older adult cohort (TASOAC) study
    • Ding C., Parameswaran V., Cicuttini F., Burgess J., Zhai G., Quinn S., et al. Association between leptin, body composition, sex and knee cartilage morphology in older adults: the Tasmanian older adult cohort (TASOAC) study. Ann Rheum Dis 2008, 67(9):1256-1261.
    • (2008) Ann Rheum Dis , vol.67 , Issue.9 , pp. 1256-1261
    • Ding, C.1    Parameswaran, V.2    Cicuttini, F.3    Burgess, J.4    Zhai, G.5    Quinn, S.6
  • 15
    • 23044502712 scopus 로고    scopus 로고
    • Knee structural alteration and BMI: a cross-sectional study
    • Ding C., Cicuttini F., Scott F., Cooley H., Jones G. Knee structural alteration and BMI: a cross-sectional study. Obes Res 2005, 13(2):350-361.
    • (2005) Obes Res , vol.13 , Issue.2 , pp. 350-361
    • Ding, C.1    Cicuttini, F.2    Scott, F.3    Cooley, H.4    Jones, G.5
  • 16
    • 39449130846 scopus 로고    scopus 로고
    • Obesity and knee osteoarthritis: new insights provided by body composition studies
    • Teichtahl A.J., Wang Y., Wluka A.E., Cicuttini F.M. Obesity and knee osteoarthritis: new insights provided by body composition studies. Obesity (Silver Spring) 2008, 16(2):232-240.
    • (2008) Obesity (Silver Spring) , vol.16 , Issue.2 , pp. 232-240
    • Teichtahl, A.J.1    Wang, Y.2    Wluka, A.E.3    Cicuttini, F.M.4
  • 17
    • 39749118008 scopus 로고    scopus 로고
    • BMI vs. body composition and radiographically defined osteoarthritis of the knee in women: a 4-year follow-up study
    • Sowers M., Yosef M., Jamadar D., Jacobson J., Karvonen-Gutierrez C., Jaffe M. BMI vs. body composition and radiographically defined osteoarthritis of the knee in women: a 4-year follow-up study. Osteoarthritis Cartilage 2008, 16(3):367-372.
    • (2008) Osteoarthritis Cartilage , vol.16 , Issue.3 , pp. 367-372
    • Sowers, M.1    Yosef, M.2    Jamadar, D.3    Jacobson, J.4    Karvonen-Gutierrez, C.5    Jaffe, M.6
  • 18
    • 84882270524 scopus 로고    scopus 로고
    • Body fat is associated with increased and lean mass with decreased knee cartilage loss in older adults: a prospective cohort study
    • Ding C., Stannus O., Cicuttini F., Antony B., Jones G. Body fat is associated with increased and lean mass with decreased knee cartilage loss in older adults: a prospective cohort study. Int J Obes 2013, 37(6):822-827.
    • (2013) Int J Obes , vol.37 , Issue.6 , pp. 822-827
    • Ding, C.1    Stannus, O.2    Cicuttini, F.3    Antony, B.4    Jones, G.5
  • 19
    • 39449122764 scopus 로고    scopus 로고
    • The longitudinal relationship between body composition and patella cartilage in healthy adults
    • Teichtahl A.J., Wang Y., Wluka A.E., Szramka M., English D.R., Giles G.G., et al. The longitudinal relationship between body composition and patella cartilage in healthy adults. Obesity (Silver Spring) 2008, 16(2):421-427.
    • (2008) Obesity (Silver Spring) , vol.16 , Issue.2 , pp. 421-427
    • Teichtahl, A.J.1    Wang, Y.2    Wluka, A.E.3    Szramka, M.4    English, D.R.5    Giles, G.G.6
  • 21
    • 84895463605 scopus 로고    scopus 로고
    • Body fat and lean mass have opposite effects on loss of knee cartilage and increase in knee pain in older adults: a prospective cohort study
    • Ding C., Stannus O., Antony B., Cicuttini F., Jones G. Body fat and lean mass have opposite effects on loss of knee cartilage and increase in knee pain in older adults: a prospective cohort study. Osteoarthritis Cartilage 2012, 20:S21.
    • (2012) Osteoarthritis Cartilage , vol.20 , pp. S21
    • Ding, C.1    Stannus, O.2    Antony, B.3    Cicuttini, F.4    Jones, G.5
  • 23
    • 84903866986 scopus 로고    scopus 로고
    • Infrapatellar fat pad in the knee: is local fat good or bad for knee osteoarthritis?
    • Han W., Cai S., Liu Z., Jin X., Wang X., Antony B., et al. Infrapatellar fat pad in the knee: is local fat good or bad for knee osteoarthritis?. Arthritis Res Ther 2014, 16(4):R145.
    • (2014) Arthritis Res Ther , vol.16 , Issue.4 , pp. R145
    • Han, W.1    Cai, S.2    Liu, Z.3    Jin, X.4    Wang, X.5    Antony, B.6
  • 25
    • 84863001000 scopus 로고    scopus 로고
    • Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage
    • de Boer T., Van Spil W., Huisman A., Polak A., Bijlsma J., Lafeber F., et al. Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage. Osteoarthritis Cartilage 2012, 20(8):846-853.
    • (2012) Osteoarthritis Cartilage , vol.20 , Issue.8 , pp. 846-853
    • de Boer, T.1    Van Spil, W.2    Huisman, A.3    Polak, A.4    Bijlsma, J.5    Lafeber, F.6
  • 26
    • 0029090011 scopus 로고
    • Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue
    • Masuzaki H., Ogawa Y., Isse N., Satoh N., Okazaki T., Shigemoto M., et al. Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue. Diabetes 1995, 44(7):855-858.
    • (1995) Diabetes , vol.44 , Issue.7 , pp. 855-858
    • Masuzaki, H.1    Ogawa, Y.2    Isse, N.3    Satoh, N.4    Okazaki, T.5    Shigemoto, M.6
  • 27
    • 79955654715 scopus 로고    scopus 로고
    • Leptin enhances MMP-1 MMP-3 and MMP-13 production in human osteoarthritis cartilage and correlates with MMP-1 and MMP-3 in synovial fluid from OA patients
    • Vuolteenaho K., Koskinen A., Nieminen R., Moilanen T., Moilanen E. Leptin enhances MMP-1 MMP-3 and MMP-13 production in human osteoarthritis cartilage and correlates with MMP-1 and MMP-3 in synovial fluid from OA patients. Clin Exp Rheumatol 2011, 29(1):57-64.
    • (2011) Clin Exp Rheumatol , vol.29 , Issue.1 , pp. 57-64
    • Vuolteenaho, K.1    Koskinen, A.2    Nieminen, R.3    Moilanen, T.4    Moilanen, E.5
  • 28
    • 69249202380 scopus 로고    scopus 로고
    • Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage-mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production
    • Vuolteenaho K., Koskinen A., Kukkonen M., Nieminen R., Paivarinta U., Moilanen T., et al. Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage-mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production. Mediators Inflamm 2009, 2009:345838.
    • (2009) Mediators Inflamm , vol.2009 , pp. 345838
    • Vuolteenaho, K.1    Koskinen, A.2    Kukkonen, M.3    Nieminen, R.4    Paivarinta, U.5    Moilanen, T.6
  • 29
    • 77956946117 scopus 로고    scopus 로고
    • Leptin plays a catabolic role on articular cartilage
    • Bao J.P., Chen W.P., Feng J., Hu P.F., Shi Z.L., Wu L.D. Leptin plays a catabolic role on articular cartilage. Mol Biol Rep 2010, 37(7):3265-3272.
    • (2010) Mol Biol Rep , vol.37 , Issue.7 , pp. 3265-3272
    • Bao, J.P.1    Chen, W.P.2    Feng, J.3    Hu, P.F.4    Shi, Z.L.5    Wu, L.D.6
  • 30
    • 70349771971 scopus 로고    scopus 로고
    • Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis
    • Griffin T.M., Huebner J.L., Kraus V.B., Guilak F. Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis. Arthritis Rheum 2009, 60(10):2935-2944.
    • (2009) Arthritis Rheum , vol.60 , Issue.10 , pp. 2935-2944
    • Griffin, T.M.1    Huebner, J.L.2    Kraus, V.B.3    Guilak, F.4
  • 31
    • 77952301751 scopus 로고    scopus 로고
    • The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study
    • Stannus O.P., Jones G., Quinn S.J., Cicuttini F.M., Dore D., Ding C. The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study. Arthritis Res Ther 2010, 12(3):R95.
    • (2010) Arthritis Res Ther , vol.12 , Issue.3 , pp. R95
    • Stannus, O.P.1    Jones, G.2    Quinn, S.J.3    Cicuttini, F.M.4    Dore, D.5    Ding, C.6
  • 32
    • 84917680165 scopus 로고    scopus 로고
    • Cross-sectional and longitudinal associations between circulating leptin and knee cartilage thickness in older adults
    • [Epub ahead of print]
    • Stannus O.P., Cao Y., Antony B., Blizzard L., Cicuttini F., Jones G., et al. Cross-sectional and longitudinal associations between circulating leptin and knee cartilage thickness in older adults. Ann Rheum Dis 2013 Sep 27, [Epub ahead of print]. 10.1136/annrheumdis-2013-203308.
    • (2013) Ann Rheum Dis
    • Stannus, O.P.1    Cao, Y.2    Antony, B.3    Blizzard, L.4    Cicuttini, F.5    Jones, G.6
  • 33
    • 84885431606 scopus 로고    scopus 로고
    • Do synovial leptin levels correlate with pain in end stage arthritis?
    • Lubbeke A., Finckh A., Puskas G.J., Suva D., Ladermann A., Bas S., et al. Do synovial leptin levels correlate with pain in end stage arthritis?. Int Orthop 2013, 37(10):2071-2079.
    • (2013) Int Orthop , vol.37 , Issue.10 , pp. 2071-2079
    • Lubbeke, A.1    Finckh, A.2    Puskas, G.J.3    Suva, D.4    Ladermann, A.5    Bas, S.6
  • 35
    • 84862134581 scopus 로고    scopus 로고
    • Sex dimorphism in the association of cardiometabolic characteristics and osteophytes-defined radiographic knee osteoarthritis among obese and non-obese adults: NHANES III
    • Karvonen-Gutierrez C.A., Sowers M.R., Heeringa S.G. Sex dimorphism in the association of cardiometabolic characteristics and osteophytes-defined radiographic knee osteoarthritis among obese and non-obese adults: NHANES III. Osteoarthritis Cartilage 2012, 20(7):614-621.
    • (2012) Osteoarthritis Cartilage , vol.20 , Issue.7 , pp. 614-621
    • Karvonen-Gutierrez, C.A.1    Sowers, M.R.2    Heeringa, S.G.3
  • 36
    • 78650674502 scopus 로고    scopus 로고
    • Adiponectin is a potential catabolic mediator in osteoarthritis cartilage
    • Kang E.H., Lee Y.J., Kim T.K., Chang C.B., Chung J.H., Shin K., et al. Adiponectin is a potential catabolic mediator in osteoarthritis cartilage. Arthritis Res Ther 2010, 12(6):R231.
    • (2010) Arthritis Res Ther , vol.12 , Issue.6 , pp. R231
    • Kang, E.H.1    Lee, Y.J.2    Kim, T.K.3    Chang, C.B.4    Chung, J.H.5    Shin, K.6
  • 38
  • 39
    • 77957697385 scopus 로고    scopus 로고
    • The synovial fluid adiponectin-leptin ratio predicts pain with knee osteoarthritis
    • Gandhi R., Takahashi M., Smith H., Rizek R., Mahomed N.N. The synovial fluid adiponectin-leptin ratio predicts pain with knee osteoarthritis. Clin Rheumatol 2010, 29(11):1223-1228.
    • (2010) Clin Rheumatol , vol.29 , Issue.11 , pp. 1223-1228
    • Gandhi, R.1    Takahashi, M.2    Smith, H.3    Rizek, R.4    Mahomed, N.N.5
  • 40
    • 49149103250 scopus 로고    scopus 로고
    • Anew player in cartilage homeostasis: adiponectin induces nitric oxide synthase type II and pro-inflammatory cytokines in chondrocytes
    • Lago R., Gomez R., Otero M., Lago F., Gallego R., Dieguez C., et al. Anew player in cartilage homeostasis: adiponectin induces nitric oxide synthase type II and pro-inflammatory cytokines in chondrocytes. Osteoarthritis Cartilage 2008, 16(9):1101-1109.
    • (2008) Osteoarthritis Cartilage , vol.16 , Issue.9 , pp. 1101-1109
    • Lago, R.1    Gomez, R.2    Otero, M.3    Lago, F.4    Gallego, R.5    Dieguez, C.6
  • 41
    • 81055126964 scopus 로고    scopus 로고
    • Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways
    • Koskinen A., Juslin S., Nieminen R., Moilanen T., Vuolteenaho K., Moilanen E. Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways. Arthritis Res Ther 2011, 13(6):R184.
    • (2011) Arthritis Res Ther , vol.13 , Issue.6 , pp. R184
    • Koskinen, A.1    Juslin, S.2    Nieminen, R.3    Moilanen, T.4    Vuolteenaho, K.5    Moilanen, E.6
  • 43
    • 77954240011 scopus 로고    scopus 로고
    • Resistin induces expression of proinflammatory cytokines and chemokines in human articular chondrocytes via transcription and messenger RNA stabilization
    • Zhang Z., Xing X., Hensley G., Chang L.W., Liao W., Abu-Amer Y., et al. Resistin induces expression of proinflammatory cytokines and chemokines in human articular chondrocytes via transcription and messenger RNA stabilization. Arthritis Rheum 2010, 62(7):1993-2003.
    • (2010) Arthritis Rheum , vol.62 , Issue.7 , pp. 1993-2003
    • Zhang, Z.1    Xing, X.2    Hensley, G.3    Chang, L.W.4    Liao, W.5    Abu-Amer, Y.6
  • 44
    • 84922349501 scopus 로고    scopus 로고
    • NAMPT (visfatin), a direct target of hypoxia-inducible factor-2alpha, is an essential catabolic regulator of osteoarthritis
    • [Epub ahead of print]
    • Yang S., Ryu J.H., Oh H., Jeon J., Kwak J.S., Kim J.H., et al. NAMPT (visfatin), a direct target of hypoxia-inducible factor-2alpha, is an essential catabolic regulator of osteoarthritis. Ann Rheum Dis 2013 Dec 17, [Epub ahead of print]. 10.1136/annrheumdis-2013-204355.
    • (2013) Ann Rheum Dis
    • Yang, S.1    Ryu, J.H.2    Oh, H.3    Jeon, J.4    Kwak, J.S.5    Kim, J.H.6
  • 45
    • 84903526594 scopus 로고    scopus 로고
    • Levels of chemerin and interleukin 8 in the synovial fluid of patients with inflammatory arthritides and osteoarthritis
    • Valcamonica E., Chighizola C.B., Comi D., De Lucia O., Pisoni L., Murgo A., et al. Levels of chemerin and interleukin 8 in the synovial fluid of patients with inflammatory arthritides and osteoarthritis. Clin Exp Rheumatol 2014, 32(2):243-250.
    • (2014) Clin Exp Rheumatol , vol.32 , Issue.2 , pp. 243-250
    • Valcamonica, E.1    Chighizola, C.B.2    Comi, D.3    De Lucia, O.4    Pisoni, L.5    Murgo, A.6
  • 46
    • 36549042103 scopus 로고    scopus 로고
    • Adipokines as emerging mediators of immune response and inflammation
    • Lago F., Dieguez C., Gomez-Reino J., Gualillo O. Adipokines as emerging mediators of immune response and inflammation. Nat Clin Pract Rheumatol 2007, 3(12):716-724.
    • (2007) Nat Clin Pract Rheumatol , vol.3 , Issue.12 , pp. 716-724
    • Lago, F.1    Dieguez, C.2    Gomez-Reino, J.3    Gualillo, O.4
  • 47
    • 42549148908 scopus 로고    scopus 로고
    • Molecular network of cartilage homeostasis and osteoarthritis
    • Hashimoto M., Nakasa T., Hikata T., Asahara H. Molecular network of cartilage homeostasis and osteoarthritis. Med Res Rev 2008, 28(3):464-481.
    • (2008) Med Res Rev , vol.28 , Issue.3 , pp. 464-481
    • Hashimoto, M.1    Nakasa, T.2    Hikata, T.3    Asahara, H.4
  • 48
    • 84871923224 scopus 로고    scopus 로고
    • Osteoarthritis synovial fluid activates pro-inflammatory cytokines in primary human chondrocytes
    • Hoff P., Buttgereit F., Burmester G.R., Jakstadt M., Gaber T., Andreas K., et al. Osteoarthritis synovial fluid activates pro-inflammatory cytokines in primary human chondrocytes. Int Orthop 2013, 37(1):145-151.
    • (2013) Int Orthop , vol.37 , Issue.1 , pp. 145-151
    • Hoff, P.1    Buttgereit, F.2    Burmester, G.R.3    Jakstadt, M.4    Gaber, T.5    Andreas, K.6
  • 50
    • 84870323722 scopus 로고    scopus 로고
    • Interleukin-17 sensitizes joint nociceptors to mechanical stimuli and contributes to arthritic pain through neuronal interleukin-17 receptors in rodents
    • Richter F., Natura G., Ebbinghaus M., von Banchet G.S., Hensellek S., Konig C., et al. Interleukin-17 sensitizes joint nociceptors to mechanical stimuli and contributes to arthritic pain through neuronal interleukin-17 receptors in rodents. Arthritis Rheum 2012, 64(12):4125-4134.
    • (2012) Arthritis Rheum , vol.64 , Issue.12 , pp. 4125-4134
    • Richter, F.1    Natura, G.2    Ebbinghaus, M.3    von Banchet, G.S.4    Hensellek, S.5    Konig, C.6
  • 51
    • 67650032606 scopus 로고    scopus 로고
    • Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: the Chingford Study
    • Livshits G., Zhai G., Hart D.J., Kato B.S., Wang H., Williams F.M., et al. Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: the Chingford Study. Arthritis Rheum 2009, 60(7):2037-2045.
    • (2009) Arthritis Rheum , vol.60 , Issue.7 , pp. 2037-2045
    • Livshits, G.1    Zhai, G.2    Hart, D.J.3    Kato, B.S.4    Wang, H.5    Williams, F.M.6
  • 52
    • 78149410926 scopus 로고    scopus 로고
    • Circulating levels of IL-6 and TNF-alpha are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults
    • Stannus O., Jones G., Cicuttini F., Parameswaran V., Quinn S., Burgess J., et al. Circulating levels of IL-6 and TNF-alpha are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults. Osteoarthritis Cartilage 2010, 18(11):1441-1447.
    • (2010) Osteoarthritis Cartilage , vol.18 , Issue.11 , pp. 1441-1447
    • Stannus, O.1    Jones, G.2    Cicuttini, F.3    Parameswaran, V.4    Quinn, S.5    Burgess, J.6
  • 53
    • 84874445047 scopus 로고    scopus 로고
    • Associations between serum levels of inflammatory markers and change in knee pain over 5 years in older adults: a prospective cohort study
    • Stannus O.P., Jones G., Blizzard L., Cicuttini F.M., Ding C. Associations between serum levels of inflammatory markers and change in knee pain over 5 years in older adults: a prospective cohort study. Ann Rheum Dis 2013, 72(4):535-540.
    • (2013) Ann Rheum Dis , vol.72 , Issue.4 , pp. 535-540
    • Stannus, O.P.1    Jones, G.2    Blizzard, L.3    Cicuttini, F.M.4    Ding, C.5
  • 54
    • 84892466722 scopus 로고    scopus 로고
    • Association between severity of knee osteoarthritis and serum and synovial fluid interleukin 17 concentrations
    • Chen B., Deng Y., Tan Y., Qin J., Chen L.B. Association between severity of knee osteoarthritis and serum and synovial fluid interleukin 17 concentrations. JInt Med Res 2014, 42(1):138-144.
    • (2014) JInt Med Res , vol.42 , Issue.1 , pp. 138-144
    • Chen, B.1    Deng, Y.2    Tan, Y.3    Qin, J.4    Chen, L.B.5
  • 56
    • 77954073360 scopus 로고    scopus 로고
    • Exercise increases interleukin-10 levels both intraarticularly and peri-synovially in patients with knee osteoarthritis: a randomized controlled trial
    • Helmark I.C., Mikkelsen U.R., Borglum J., Rothe A., Petersen M.C., Andersen O., et al. Exercise increases interleukin-10 levels both intraarticularly and peri-synovially in patients with knee osteoarthritis: a randomized controlled trial. Arthritis Res Ther 2010, 12(4):R126.
    • (2010) Arthritis Res Ther , vol.12 , Issue.4 , pp. R126
    • Helmark, I.C.1    Mikkelsen, U.R.2    Borglum, J.3    Rothe, A.4    Petersen, M.C.5    Andersen, O.6
  • 57
    • 84874021754 scopus 로고    scopus 로고
    • Obesity and C-reactive protein in various populations: a systematic review and meta-analysis
    • Choi J., Joseph L., Pilote L. Obesity and C-reactive protein in various populations: a systematic review and meta-analysis. Obes Rev 2013, 14(3):232-244.
    • (2013) Obes Rev , vol.14 , Issue.3 , pp. 232-244
    • Choi, J.1    Joseph, L.2    Pilote, L.3
  • 58
  • 59
    • 41149094180 scopus 로고    scopus 로고
    • High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life
    • Hanna F.S., Bell R.J., Cicuttini F.M., Davison S.L., Wluka A.E., Davis S.R. High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life. Arthritis Res Ther 2008, 10(1):R27.
    • (2008) Arthritis Res Ther , vol.10 , Issue.1 , pp. R27
    • Hanna, F.S.1    Bell, R.J.2    Cicuttini, F.M.3    Davison, S.L.4    Wluka, A.E.5    Davis, S.R.6
  • 60
    • 34247569933 scopus 로고    scopus 로고
    • Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis
    • Pearle A.D., Scanzello C.R., George S., Mandl L.A., DiCarlo E.F., Peterson M., et al. Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis. Osteoarthritis Cartilage 2007, 15(5):516-523.
    • (2007) Osteoarthritis Cartilage , vol.15 , Issue.5 , pp. 516-523
    • Pearle, A.D.1    Scanzello, C.R.2    George, S.3    Mandl, L.A.4    DiCarlo, E.F.5    Peterson, M.6
  • 61
    • 84918787550 scopus 로고    scopus 로고
    • Circulating C-reactive protein in osteoarthritis: a systematic review and meta-analysis
    • accepted
    • Jin X., Beguerie J., Zhang W., Blizzard L., Otahal P., Jones G., et al. Circulating C-reactive protein in osteoarthritis: a systematic review and meta-analysis. Ann Rheum Dis 2014, 72. accepted.
    • (2014) Ann Rheum Dis , vol.72
    • Jin, X.1    Beguerie, J.2    Zhang, W.3    Blizzard, L.4    Otahal, P.5    Jones, G.6
  • 62
    • 84866033089 scopus 로고    scopus 로고
    • Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases
    • Happonen K.E., Heinegard D., Saxne T., Blom A.M. Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases. Immunobiology 2012, 217(11):1088-1096.
    • (2012) Immunobiology , vol.217 , Issue.11 , pp. 1088-1096
    • Happonen, K.E.1    Heinegard, D.2    Saxne, T.3    Blom, A.M.4
  • 63
    • 84856100338 scopus 로고    scopus 로고
    • Identification of a central role for complement in osteoarthritis
    • Wang Q., Rozelle A.L., Lepus C.M., Scanzello C.R., Song J.J., Larsen D.M., et al. Identification of a central role for complement in osteoarthritis. Nat Med 2011, 17(12):1674-1679.
    • (2011) Nat Med , vol.17 , Issue.12 , pp. 1674-1679
    • Wang, Q.1    Rozelle, A.L.2    Lepus, C.M.3    Scanzello, C.R.4    Song, J.J.5    Larsen, D.M.6
  • 64
    • 84918782582 scopus 로고    scopus 로고
    • Complement activation and regulation in early and advanced stage osteoarthritis
    • A37-A
    • Scott J.L., Scanzello C.R., Dragomir C., Crow M.K. Complement activation and regulation in early and advanced stage osteoarthritis. Ann Rheum Dis 2011, 69(Suppl 2). A37-A.
    • (2011) Ann Rheum Dis , vol.69 SUPPL 2
    • Scott, J.L.1    Scanzello, C.R.2    Dragomir, C.3    Crow, M.K.4
  • 65
    • 67449093965 scopus 로고    scopus 로고
    • Ametabolic aspect of osteoarthritis: lipid as a possible contributor to the pathogenesis of cartilage degradation
    • Masuko K., Murata M., Suematsu N., Okamoto K., Yudoh K., Nakamura H., et al. Ametabolic aspect of osteoarthritis: lipid as a possible contributor to the pathogenesis of cartilage degradation. Clin Exp Rheumatol 2009, 27(2):347-353.
    • (2009) Clin Exp Rheumatol , vol.27 , Issue.2 , pp. 347-353
    • Masuko, K.1    Murata, M.2    Suematsu, N.3    Okamoto, K.4    Yudoh, K.5    Nakamura, H.6
  • 66
    • 0034733622 scopus 로고    scopus 로고
    • Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation. Possible role in cartilage aging and the pathogenesis of osteoarthritis
    • Tiku M.L., Shah R., Allison G.T. Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation. Possible role in cartilage aging and the pathogenesis of osteoarthritis. JBiol Chem 2000, 275(26):20069-20076.
    • (2000) JBiol Chem , vol.275 , Issue.26 , pp. 20069-20076
    • Tiku, M.L.1    Shah, R.2    Allison, G.T.3
  • 67
    • 77954700085 scopus 로고    scopus 로고
    • Impaired expression of genes regulating cholesterol efflux in human osteoarthritic chondrocytes
    • Tsezou A., Iliopoulos D., Malizos K.N., Simopoulou T. Impaired expression of genes regulating cholesterol efflux in human osteoarthritic chondrocytes. JOrthop Res 2010, 28(8):1033-1039.
    • (2010) JOrthop Res , vol.28 , Issue.8 , pp. 1033-1039
    • Tsezou, A.1    Iliopoulos, D.2    Malizos, K.N.3    Simopoulou, T.4
  • 68
    • 78650947739 scopus 로고    scopus 로고
    • Lipid metabolism and osteoarthritis: lessons from atherosclerosis
    • Gkretsi V., Simopoulou T., Tsezou A. Lipid metabolism and osteoarthritis: lessons from atherosclerosis. Prog Lipid Res 2011, 50(2):133-140.
    • (2011) Prog Lipid Res , vol.50 , Issue.2 , pp. 133-140
    • Gkretsi, V.1    Simopoulou, T.2    Tsezou, A.3
  • 69
    • 77952488264 scopus 로고    scopus 로고
    • Total cholesterol and triglycerides are associated with the development of new bone marrow lesions in asymptomatic middle-aged women - a prospective cohort study
    • Davies-Tuck M.L., Hanna F., Davis S.R., Bell R.J., Davison S.L., Wluka A.E., et al. Total cholesterol and triglycerides are associated with the development of new bone marrow lesions in asymptomatic middle-aged women - a prospective cohort study. Arthritis Res Ther 2009, 11(6):R181.
    • (2009) Arthritis Res Ther , vol.11 , Issue.6 , pp. R181
    • Davies-Tuck, M.L.1    Hanna, F.2    Davis, S.R.3    Bell, R.J.4    Davison, S.L.5    Wluka, A.E.6
  • 70
    • 84855893551 scopus 로고    scopus 로고
    • Alongitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee
    • Dore D., de Hoog J., Giles G., Ding C., Cicuttini F., Jones G. Alongitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee. Arthritis Res Ther 2012, 14(1):R13.
    • (2012) Arthritis Res Ther , vol.14 , Issue.1 , pp. R13
    • Dore, D.1    de Hoog, J.2    Giles, G.3    Ding, C.4    Cicuttini, F.5    Jones, G.6
  • 71
    • 84945207686 scopus 로고    scopus 로고
    • Dietary fatty acid content regulates wound repair andthe pathogenesis of osteoarthritis following joint injury
    • [Epub ahead of print]
    • Wu C.L., Jain D., McNeill J.N., Little D., Anderson J.A., Huebner J.L., et al. Dietary fatty acid content regulates wound repair andthe pathogenesis of osteoarthritis following joint injury. Ann Rheum Dis 2014 July 10, [Epub ahead of print]. 10.1136/annrheumdis-2014-205601.
    • (2014) Ann Rheum Dis
    • Wu, C.L.1    Jain, D.2    McNeill, J.N.3    Little, D.4    Anderson, J.A.5    Huebner, J.L.6
  • 72
    • 84859426389 scopus 로고    scopus 로고
    • Association of plasma n-6 and n-3 polyunsaturated fatty acids with synovitis in the knee: the MOST study
    • Baker K.R., Matthan N.R., Lichtenstein A.H., Niu J., Guermazi A., Roemer F., et al. Association of plasma n-6 and n-3 polyunsaturated fatty acids with synovitis in the knee: the MOST study. Osteoarthritis Cartilage 2012, 20(5):382-387.
    • (2012) Osteoarthritis Cartilage , vol.20 , Issue.5 , pp. 382-387
    • Baker, K.R.1    Matthan, N.R.2    Lichtenstein, A.H.3    Niu, J.4    Guermazi, A.5    Roemer, F.6
  • 73
    • 84859086298 scopus 로고    scopus 로고
    • Diabetes-induced osteoarthritis: from a new paradigm to a new phenotype
    • Berenbaum F. Diabetes-induced osteoarthritis: from a new paradigm to a new phenotype. Postgrad Med J 2012, 88(1038):240-242.
    • (2012) Postgrad Med J , vol.88 , Issue.1038 , pp. 240-242
    • Berenbaum, F.1
  • 74
    • 80855130827 scopus 로고    scopus 로고
    • Inflammatory effect of advanced glycation end products on human meniscal cells from osteoarthritic knees
    • Hiraiwa H., Sakai T., Mitsuyama H., Hamada T., Yamamoto R., Omachi T., et al. Inflammatory effect of advanced glycation end products on human meniscal cells from osteoarthritic knees. Inflamm Res 2011, 60(11):1039-1048.
    • (2011) Inflamm Res , vol.60 , Issue.11 , pp. 1039-1048
    • Hiraiwa, H.1    Sakai, T.2    Mitsuyama, H.3    Hamada, T.4    Yamamoto, R.5    Omachi, T.6
  • 75
    • 84863783685 scopus 로고    scopus 로고
    • Increased fasting serum glucose concentration is associated with adverse knee structural changes in adults with no knee symptoms and diabetes
    • Davies-Tuck M.L., Wang Y., Wluka A.E., Berry P.A., Giles G.G., English D.R., et al. Increased fasting serum glucose concentration is associated with adverse knee structural changes in adults with no knee symptoms and diabetes. Maturitas 2012, 72(4):373-378.
    • (2012) Maturitas , vol.72 , Issue.4 , pp. 373-378
    • Davies-Tuck, M.L.1    Wang, Y.2    Wluka, A.E.3    Berry, P.A.4    Giles, G.G.5    English, D.R.6
  • 76
    • 66049111676 scopus 로고    scopus 로고
    • Serum levels of vitamin D, sunlight exposure, and knee cartilage loss in older adults: the Tasmanian older adult cohort study
    • Ding C., Cicuttini F., Parameswaran V., Burgess J., Quinn S., Jones G. Serum levels of vitamin D, sunlight exposure, and knee cartilage loss in older adults: the Tasmanian older adult cohort study. Arthritis Rheum 2009, 60(5):1381-1389.
    • (2009) Arthritis Rheum , vol.60 , Issue.5 , pp. 1381-1389
    • Ding, C.1    Cicuttini, F.2    Parameswaran, V.3    Burgess, J.4    Quinn, S.5    Jones, G.6
  • 77
    • 79955615930 scopus 로고    scopus 로고
    • Association between serum vitamin D deficiency and knee osteoarthritis
    • Heidari B., Heidari P., Hajian-Tilaki K. Association between serum vitamin D deficiency and knee osteoarthritis. Int Orthop 2011, 35(11):1627-1631.
    • (2011) Int Orthop , vol.35 , Issue.11 , pp. 1627-1631
    • Heidari, B.1    Heidari, P.2    Hajian-Tilaki, K.3
  • 78
    • 84895430684 scopus 로고    scopus 로고
    • Moderate vitamin D deficiency is associated with changes in knee and hip pain in older adults: a 5-year longitudinal study
    • Laslett L.L., Quinn S., Burgess J.R., Parameswaran V., Winzenberg T.M., Jones G., et al. Moderate vitamin D deficiency is associated with changes in knee and hip pain in older adults: a 5-year longitudinal study. Ann Rheum Dis 2013, 73(4):697-703.
    • (2013) Ann Rheum Dis , vol.73 , Issue.4 , pp. 697-703
    • Laslett, L.L.1    Quinn, S.2    Burgess, J.R.3    Parameswaran, V.4    Winzenberg, T.M.5    Jones, G.6
  • 79
    • 77951117713 scopus 로고    scopus 로고
    • Role of microRNAs in obesity and the metabolic syndrome
    • Heneghan H.M., Miller N., Kerin M.J. Role of microRNAs in obesity and the metabolic syndrome. Obes Rev 2010, 11(5):354-361.
    • (2010) Obes Rev , vol.11 , Issue.5 , pp. 354-361
    • Heneghan, H.M.1    Miller, N.2    Kerin, M.J.3
  • 80
  • 81
    • 56649084972 scopus 로고    scopus 로고
    • Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks
    • Iliopoulos D., Malizos K.N., Oikonomou P., Tsezou A. Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS One 2008, 3(11):e3740.
    • (2008) PLoS One , vol.3 , Issue.11 , pp. e3740
    • Iliopoulos, D.1    Malizos, K.N.2    Oikonomou, P.3    Tsezou, A.4
  • 82
    • 69449103973 scopus 로고    scopus 로고
    • MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses
    • Miyaki S., Nakasa T., Otsuki S., Grogan S.P., Higashiyama R., Inoue A., et al. MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses. Arthritis Rheum 2009, 60(9):2723-2730.
    • (2009) Arthritis Rheum , vol.60 , Issue.9 , pp. 2723-2730
    • Miyaki, S.1    Nakasa, T.2    Otsuki, S.3    Grogan, S.P.4    Higashiyama, R.5    Inoue, A.6
  • 84
    • 84891747233 scopus 로고    scopus 로고
    • Overexpression of hsa-miR-148a promotes cartilage production and inhibits cartilage degradation by osteoarthritic chondrocytes
    • Vonk L.A., Kragten A.H., Dhert W.J., Saris D.B., Creemers L.B. Overexpression of hsa-miR-148a promotes cartilage production and inhibits cartilage degradation by osteoarthritic chondrocytes. Osteoarthritis Cartilage 2013, 21(1):145-153.
    • (2013) Osteoarthritis Cartilage , vol.21 , Issue.1 , pp. 145-153
    • Vonk, L.A.1    Kragten, A.H.2    Dhert, W.J.3    Saris, D.B.4    Creemers, L.B.5
  • 85
    • 84884619722 scopus 로고    scopus 로고
    • Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial
    • Messier S.P., Mihalko S.L., Legault C., Miller G.D., Nicklas B.J., DeVita P., et al. Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial. JAMA 2013, 310(12):1263-1273.
    • (2013) JAMA , vol.310 , Issue.12 , pp. 1263-1273
    • Messier, S.P.1    Mihalko, S.L.2    Legault, C.3    Miller, G.D.4    Nicklas, B.J.5    DeVita, P.6
  • 86
    • 84872773960 scopus 로고    scopus 로고
    • Influence of weight loss, body composition, and lifestyle behaviors on plasma adipokines: a randomized weight loss trial in older men and women with symptomatic knee osteoarthritis
    • Miller G.D., Jenks M.Z., Vendela M., Norris J.L., Muday G.K. Influence of weight loss, body composition, and lifestyle behaviors on plasma adipokines: a randomized weight loss trial in older men and women with symptomatic knee osteoarthritis. JObes 2012, 2012:708505.
    • (2012) JObes , vol.2012 , pp. 708505
    • Miller, G.D.1    Jenks, M.Z.2    Vendela, M.3    Norris, J.L.4    Muday, G.K.5
  • 87
    • 78650676944 scopus 로고    scopus 로고
    • Benefits of massive weight loss on symptoms, systemic inflammation and cartilage turnover in obese patients with knee osteoarthritis
    • Richette P., Poitou C., Garnero P., Vicaut E., Bouillot J.L., Lacorte J.M., et al. Benefits of massive weight loss on symptoms, systemic inflammation and cartilage turnover in obese patients with knee osteoarthritis. Ann Rheum Dis 2011, 70(1):139-144.
    • (2011) Ann Rheum Dis , vol.70 , Issue.1 , pp. 139-144
    • Richette, P.1    Poitou, C.2    Garnero, P.3    Vicaut, E.4    Bouillot, J.L.5    Lacorte, J.M.6
  • 88
    • 2142817993 scopus 로고    scopus 로고
    • Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial
    • Nicklas B.J., Ambrosius W., Messier S.P., Miller G.D., Penninx B.W., Loeser R.F., et al. Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial. Am J Clin Nutr 2004, 79(4):544-551.
    • (2004) Am J Clin Nutr , vol.79 , Issue.4 , pp. 544-551
    • Nicklas, B.J.1    Ambrosius, W.2    Messier, S.P.3    Miller, G.D.4    Penninx, B.W.5    Loeser, R.F.6
  • 89
    • 84879691407 scopus 로고    scopus 로고
    • Effects of glucosamine sulfate and exercise therapy on serum leptin levels in patients with knee osteoarthritis: preliminary results of randomized controlled clinical trial
    • Durmus D., Alayli G., Aliyazicioglu Y., Buyukakincak O., Canturk F. Effects of glucosamine sulfate and exercise therapy on serum leptin levels in patients with knee osteoarthritis: preliminary results of randomized controlled clinical trial. Rheumatol Int 2013, 33(3):593-599.
    • (2013) Rheumatol Int , vol.33 , Issue.3 , pp. 593-599
    • Durmus, D.1    Alayli, G.2    Aliyazicioglu, Y.3    Buyukakincak, O.4    Canturk, F.5
  • 90
    • 62549104691 scopus 로고    scopus 로고
    • Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebo-controlled study
    • Chevalier X., Goupille P., Beaulieu A.D., Burch F.X., Bensen W.G., Conrozier T., et al. Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum 2009, 61(3):344-352.
    • (2009) Arthritis Rheum , vol.61 , Issue.3 , pp. 344-352
    • Chevalier, X.1    Goupille, P.2    Beaulieu, A.D.3    Burch, F.X.4    Bensen, W.G.5    Conrozier, T.6
  • 91
    • 79960862976 scopus 로고    scopus 로고
    • Arandomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee
    • Cohen S.B., Proudman S., Kivitz A.J., Burch F.X., Donohue J.P., Burstein D., et al. Arandomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee. Arthritis Res Ther 2011, 13(4):R125.
    • (2011) Arthritis Res Ther , vol.13 , Issue.4 , pp. R125
    • Cohen, S.B.1    Proudman, S.2    Kivitz, A.J.3    Burch, F.X.4    Donohue, J.P.5    Burstein, D.6
  • 93
    • 84925542702 scopus 로고    scopus 로고
    • Adalimumab in patients with hand osteoarthritis refractory to analgesics and NSAIDs: a randomised, multicentre, double-blind, placebo-controlled trial
    • [Epub ahead of print]
    • Chevalier X., Ravaud P., Maheu E., Baron G., Rialland A., Vergnaud P., et al. Adalimumab in patients with hand osteoarthritis refractory to analgesics and NSAIDs: a randomised, multicentre, double-blind, placebo-controlled trial. Ann Rheum Dis 2014 May 9, [Epub ahead of print]. 10.1136/annrheumdis-2014-205348.
    • (2014) Ann Rheum Dis
    • Chevalier, X.1    Ravaud, P.2    Maheu, E.3    Baron, G.4    Rialland, A.5    Vergnaud, P.6
  • 94
    • 84860918903 scopus 로고    scopus 로고
    • Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: a double blind, randomised trial on structure modification
    • Verbruggen G., Wittoek R., Vander Cruyssen B., Elewaut D. Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: a double blind, randomised trial on structure modification. Ann Rheum Dis 2012, 71(6):891-898.
    • (2012) Ann Rheum Dis , vol.71 , Issue.6 , pp. 891-898
    • Verbruggen, G.1    Wittoek, R.2    Vander Cruyssen, B.3    Elewaut, D.4
  • 95
    • 84866904391 scopus 로고    scopus 로고
    • Targeting tumour necrosis factor alleviates signs and symptoms of inflammatory osteoarthritis of the knee
    • Maksymowych W.P., Russell A.S., Chiu P., Yan A., Jones N., Clare T., et al. Targeting tumour necrosis factor alleviates signs and symptoms of inflammatory osteoarthritis of the knee. Arthritis Res Ther 2012, 14(5):R206.
    • (2012) Arthritis Res Ther , vol.14 , Issue.5 , pp. R206
    • Maksymowych, W.P.1    Russell, A.S.2    Chiu, P.3    Yan, A.4    Jones, N.5    Clare, T.6
  • 97
    • 84872066639 scopus 로고    scopus 로고
    • Associations between statin use and changes in pain, function and structural progression: a longitudinal study of persons with knee osteoarthritis
    • Riddle D.L., Moxley G., Dumenci L. Associations between statin use and changes in pain, function and structural progression: a longitudinal study of persons with knee osteoarthritis. Ann Rheum Dis 2013, 72(2):196-203.
    • (2013) Ann Rheum Dis , vol.72 , Issue.2 , pp. 196-203
    • Riddle, D.L.1    Moxley, G.2    Dumenci, L.3
  • 98
    • 84879550749 scopus 로고    scopus 로고
    • Statin use and clinical osteoarthritis in the general population: a longitudinal study
    • Kadam U.T., Blagojevic M., Belcher J. Statin use and clinical osteoarthritis in the general population: a longitudinal study. JGen Intern Med 2013, 28(7):943-949.
    • (2013) JGen Intern Med , vol.28 , Issue.7 , pp. 943-949
    • Kadam, U.T.1    Blagojevic, M.2    Belcher, J.3
  • 99
    • 84875167607 scopus 로고    scopus 로고
    • Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: a randomized controlled trial
    • Belenchia A.M., Tosh A.K., Hillman L.S., Peterson C.A. Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: a randomized controlled trial. Am J Clin Nutr 2013, 97(4):774-781.
    • (2013) Am J Clin Nutr , vol.97 , Issue.4 , pp. 774-781
    • Belenchia, A.M.1    Tosh, A.K.2    Hillman, L.S.3    Peterson, C.A.4
  • 100
    • 84872070090 scopus 로고    scopus 로고
    • Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial
    • McAlindon T., LaValley M., Schneider E., Nuite M., Lee J.Y., Price L.L., et al. Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial. JAMA 2013, 309(2):155-162.
    • (2013) JAMA , vol.309 , Issue.2 , pp. 155-162
    • McAlindon, T.1    LaValley, M.2    Schneider, E.3    Nuite, M.4    Lee, J.Y.5    Price, L.L.6
  • 101
    • 84885954946 scopus 로고    scopus 로고
    • Does vitamin D improve osteoarthritis of the knee: a randomized controlled pilot trial
    • Sanghi D., Mishra A., Sharma A.C., Singh A., Natu S.M., Agarwal S., et al. Does vitamin D improve osteoarthritis of the knee: a randomized controlled pilot trial. Clin Orthop Relat Res 2013, 471(11):3556-3562.
    • (2013) Clin Orthop Relat Res , vol.471 , Issue.11 , pp. 3556-3562
    • Sanghi, D.1    Mishra, A.2    Sharma, A.C.3    Singh, A.4    Natu, S.M.5    Agarwal, S.6
  • 102
    • 84864529300 scopus 로고    scopus 로고
    • Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial
    • Cao Y., Jones G., Cicuttini F., Winzenberg T., Wluka A., Sharman J., et al. Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial. Trials 2012, 13:131.
    • (2012) Trials , vol.13 , pp. 131
    • Cao, Y.1    Jones, G.2    Cicuttini, F.3    Winzenberg, T.4    Wluka, A.5    Sharman, J.6
  • 103
    • 79955890241 scopus 로고    scopus 로고
    • MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis
    • Li X., Gibson G., Kim J.S., Kroin J., Xu S., van Wijnen A.J., et al. MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis. Gene 2011, 480(1-2):34-41.
    • (2011) Gene , vol.480 , Issue.1-2 , pp. 34-41
    • Li, X.1    Gibson, G.2    Kim, J.S.3    Kroin, J.4    Xu, S.5    van Wijnen, A.J.6
  • 104
    • 0035211844 scopus 로고    scopus 로고
    • Differential roles of nitric oxide and oxygen radicals in chondrocytes affected by osteoarthritis and rheumatoid arthritis
    • Mazzetti I., Grigolo B., Pulsatelli L., Dolzani P., Silvestri T., Roseti L., et al. Differential roles of nitric oxide and oxygen radicals in chondrocytes affected by osteoarthritis and rheumatoid arthritis. Clin Sci 2001, 101(6):593-599.
    • (2001) Clin Sci , vol.101 , Issue.6 , pp. 593-599
    • Mazzetti, I.1    Grigolo, B.2    Pulsatelli, L.3    Dolzani, P.4    Silvestri, T.5    Roseti, L.6
  • 105
    • 42149126726 scopus 로고    scopus 로고
    • Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis
    • Davies C.M., Guilak F., Weinberg J.B., Fermor B. Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis. Osteoarthritis Cartilage 2008, 16(5):624-630.
    • (2008) Osteoarthritis Cartilage , vol.16 , Issue.5 , pp. 624-630
    • Davies, C.M.1    Guilak, F.2    Weinberg, J.B.3    Fermor, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.