Leptin enhances MMP-1, MMP-3 and MMP-13 production in human osteoarthritic cartilage and correlates with MMP-1 and MMP-3 in synovial fluid from oa patients

Clinical and Experimental Rheumatology

Volumn 29, Issue 1, 2011, Pages 57-64

  Koskinen, Anna ^a   Vuolteenaho, Katriina ^a   Nieminen, Riina ^a   Moilanen, Teemu ^a,b   Moilanen, Eeva ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b Coxa Hospital for Joint Replacement ^*  (Finland)

Author keywords

Adipokines; Cartilage; Leptin; Matrix metalloproteinases; Osteoarthritis

Indexed keywords

COLLAGENASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; NEUTROPHIL COLLAGENASE; PROTEIN KINASE C; STROMELYSIN;

AGED; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME IMMUNOASSAY; ENZYME SYNTHESIS; FEMALE; HUMAN; HUMAN TISSUE; KNEE ARTHROPLASTY; KNEE MENISCUS; KNEE OSTEOARTHRITIS; MALE; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SYNOVIAL FLUID LEVEL; UPREGULATION; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL CULTURE; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; SYNOVIAL FLUID;

AGED; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; FEMALE; HUMANS; LEPTIN; MALE; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 3; NF-KAPPA B; OSTEOARTHRITIS, KNEE; PROTEIN KINASE C; SYNOVIAL FLUID;

EID: 79955654715     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Article

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