NAMPT (visfatin), a direct target of hypoxiainducible factor-2α, is an essential catabolic regulator of osteoarthritis

Annals of the Rheumatic Diseases

Volumn 74, Issue 3, 2015, Pages 595-602

  Yang, Siyoung ^a,b   Ryu, Je Hwang ^c   Oh, Hwanhee ^a   Jeon, Jimin ^a   Kwak, Ji Sun ^a   Kim, Jin Hong ^a   Kim, Hyun Ah ^d   Chun, Churl Hong ^e   Chun, Jang Soo ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Chonnam National University   (South Korea)

^d Hallym University   (South Korea)

^e Wonkwang University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE 3; DAPORINAD; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MACROPHAGE ELASTASE; MESSENGER RNA; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; STROMELYSIN; AGGRECAN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; COLLAGEN TYPE 2; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; MATRIX METALLOPROTEINASE;

ADENOVIRIDAE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE; CARTILAGE CELL; CONTROLLED STUDY; ENZYME DEGRADATION; GAIN OF FUNCTION MUTATION; HUMAN; HUMAN TISSUE; LOSS OF FUNCTION MUTATION; MALE; MENISCAL SURGERY; MOUSE; NAMPT GENE; NONHUMAN; OSTEOARTHRITIS; PATHOGENESIS; PROTEIN EXPRESSION; ANIMAL; ARTICULAR CARTILAGE; C57BL MOUSE; CYTOLOGY; EXPERIMENTAL ARTHRITIS; KNEE MENISCUS; METABOLISM; SURGERY; UPREGULATION;

AGGRECANS; ANIMALS; ARTHRITIS, EXPERIMENTAL; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARTILAGE, ARTICULAR; CHONDROCYTES; COLLAGEN TYPE II; HUMANS; MATRIX METALLOPROTEINASES; MENISCI, TIBIAL; MICE; MICE, INBRED C57BL; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; OSTEOARTHRITIS; UP-REGULATION;

EID: 84922349501     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2013-204355     Document Type: Article

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