Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis

Arthritis and Rheumatism

Volumn 60, Issue 10, 2009, Pages 2935-2944

  Griffin, Timothy M ^a   Huebner, Janet L ^b   Kraus, Virginia B ^b   Guilak, Farshid ^b  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; LEPTIN; LEPTIN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY FAT; C57BL 6 MOUSE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; GENE DELETION; HISTOPATHOLOGY; IMMUNOASSAY; IMMUNOREGULATION; INCIDENCE; INFLAMMATION; JOINT DEGENERATION; KERATINOCYTE; KNEE OSTEOARTHRITIS; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECEPTOR GENE; RISK FACTOR; SIGNAL TRANSDUCTION; TRABECULAR BONE;

ADIPOSITY; ANIMALS; BIOMECHANICS; BODY COMPOSITION; BONE AND BONES; BONE DENSITY; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; INFLAMMATION; JOINTS; LEPTIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY, MORBID; OSTEOARTHRITIS; RECEPTORS, LEPTIN; RISK FACTORS; SIGNAL TRANSDUCTION;

EID: 70349771971     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24854     Document Type: Article

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