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Volumn 8, Issue 1, 2014, Pages 103-114

Antiepileptic drugs influences on body weight in people with epilepsy

Author keywords

adiponectin; antiepileptic drugs; galanin; ghrelin; insulin; leptin; metabolic adverse effects; neuropeptide Y; obesity; weight

Indexed keywords

ADIPONECTIN; ANTICONVULSIVE AGENT; GALANIN; GHRELIN; INSULIN; LEPTIN; NEUROPEPTIDE Y; VALPROIC ACID; HORMONE; NEUROPEPTIDE;

EID: 84916930962     PISSN: 17512433     EISSN: 17512441     Source Type: Journal    
DOI: 10.1586/17512433.2015.991716     Document Type: Review
Times cited : (51)

References (156)
  • 1
    • 0035060226 scopus 로고    scopus 로고
    • On the association between valproate and polycystic ovary syndrome: A response and an alternative view
    • Isojärvi JI, Taubøll E, Tapanainen JS, et al. On the association between valproate and polycystic ovary syndrome: a response and an alternative view. Epilepsia 2001;42(3): 305-10
    • (2001) Epilepsia , vol.42 , Issue.3 , pp. 305-310
    • Isojärvi, J.I.1    Taubøll, E.2    Tapanainen, J.S.3
  • 2
    • 0036091246 scopus 로고    scopus 로고
    • Serum insulin and leptin levels in valproate-associated obesity
    • Pylvänen V, Knip M, Pakarinen A, et al. Serum insulin and leptin levels in valproate-associated obesity. Epilepsia 2002; 43(5):514-17
    • (2002) Epilepsia , vol.43 , Issue.5 , pp. 514-517
    • Pylvänen, V.1    Knip, M.2    Pakarinen, A.3
  • 3
    • 0035987274 scopus 로고    scopus 로고
    • Insulin resistance in epileptic girls who gain weight after therapy with valproic acid
    • Verrotti A, Basciani F, De Simone M, et al. Insulin resistance in epileptic girls who gain weight after therapy with valproic acid. J Child Neurol 2002;17(4):265-8
    • (2002) J Child Neurol , vol.17 , Issue.4 , pp. 265-268
    • Verrotti, A.1    Basciani, F.2    De Simone, M.3
  • 4
    • 0042840536 scopus 로고    scopus 로고
    • Predictors of weight loss in adults with topiramate-treated epilepsy
    • Ben-Menachem E, Axelsen M, Johanson EH, et al. Predictors of weight loss in adults with topiramate-treated epilepsy. Obes Res 2003;11(4):556-62
    • (2003) Obes Res , vol.11 , Issue.4 , pp. 556-562
    • Ben-Menachem, E.1    Axelsen, M.2    Johanson, E.H.3
  • 5
    • 0041331539 scopus 로고    scopus 로고
    • Effect of antiepileptic drugs on bodyweight: Overview and clinical implications for the treatment of epilepsy
    • Biton V. Effect of antiepileptic drugs on bodyweight: overview and clinical implications for the treatment of epilepsy. CNS Drugs 2003;17(11):781-91
    • (2003) CNS Drugs , vol.17 , Issue.11 , pp. 781-791
    • Biton, V.1
  • 6
    • 34249780805 scopus 로고    scopus 로고
    • Leptin and insulin homeostasis in epilepsy: Relation to weight adverse conditions
    • Hamed SA. Leptin and insulin homeostasis in epilepsy: relation to weight adverse conditions. Epilepsy Res 2007;75(1):1-9
    • (2007) Epilepsy Res , vol.75 , Issue.1 , pp. 1-9
    • Hamed, S.A.1
  • 7
    • 64449085683 scopus 로고    scopus 로고
    • States of serum leptin and insulin in children with epilepsy: Risk predictors of weight gain
    • Hamed SA, Fida NM, Hamed EA. States of serum leptin and insulin in children with epilepsy: risk predictors of weight gain. Eur J Paediatr Neurol 2009;13(3):261-8
    • (2009) Eur J Paediatr Neurol , vol.13 , Issue.3 , pp. 261-268
    • Hamed, S.A.1    Fida, N.M.2    Hamed, E.A.3
  • 8
    • 3242788750 scopus 로고    scopus 로고
    • Amygdaloid kindled seizures induce weight gain that reflects left hemisphere dominance in rats
    • Bhatt R, Bhatt S, Rameshwar P, Siegel A. Amygdaloid kindled seizures induce weight gain that reflects left hemisphere dominance in rats. Physiol Behav 2004;82(2-3):581-7
    • (2004) Physiol Behav , vol.82 , Issue.2-3 , pp. 581-587
    • Bhatt, R.1    Bhatt, S.2    Rameshwar, P.3    Siegel, A.4
  • 9
    • 0031711383 scopus 로고    scopus 로고
    • Involvement of basolateral nucleus and central nucleus of amygdala in the regulation of ingestive behavior in rat
    • Ganaraj B, Jeganathan PS. Involvement of basolateral nucleus and central nucleus of amygdala in the regulation of ingestive behavior in rat. Indian J Med Res 1998;108:98-103
    • (1998) Indian J Med Res , vol.108 , pp. 98-103
    • Ganaraj, B.1    Jeganathan, P.S.2
  • 11
    • 84907499945 scopus 로고    scopus 로고
    • Obesity and its association with generalized epilepsy, idiopathic syndrome, and family history of epilepsy
    • Ladino LD, Ronquillo LH, Tellez-Zenteno JF. Obesity and its association with generalized epilepsy, idiopathic syndrome, and family history of epilepsy. Epileptic Disord 2014;16(3): 343-53
    • (2014) Epileptic Disord , vol.16 , Issue.3 , pp. 343-353
    • Ladino, L.D.1    Ronquillo, L.H.2    Tellez-Zenteno, J.F.3
  • 13
    • 0030852379 scopus 로고
    • Weight gain in epileptic patients during treatment with valproic acid: A retrospective study
    • Corman CL, Leung NM, Guberman AH. Weight gain in epileptic patients during treatment with valproic acid: a retrospective study. Can J Neurol Sci 1977;24(3):240-4
    • (1977) Can J Neurol Sci , vol.24 , Issue.3 , pp. 240-244
    • Corman, C.L.1    Leung, N.M.2    Guberman, A.H.3
  • 14
    • 0031005862 scopus 로고    scopus 로고
    • Weight gain with valproate or carbamazepine-A reappraisal
    • Easter D, O'Brvan-Tear CG, Verity C. Weight gain with valproate or carbamazepine-A reappraisal. Seizure 1997; 6(2):121-5
    • (1997) Seizure , vol.6 , Issue.2 , pp. 121-125
    • Easter, D.1    O'brvan-Tear, C.G.2    Verity, C.3
  • 15
    • 0343445201 scopus 로고    scopus 로고
    • The effects of valproate, carbamazepine, and oxcarbamazepine on growth and sexual maturation in girls with epilepsy
    • Rättyä J, Vainionpää L, Knip M, et al. The effects of valproate, carbamazepine, and oxcarbamazepine on growth and sexual maturation in girls with epilepsy. Pediatrics 1999;103(3):588-93
    • (1999) Pediatrics , vol.103 , Issue.3 , pp. 588-593
    • Rättyä, J.1    Vainionpää, L.2    Knip, M.3
  • 16
    • 0033551501 scopus 로고    scopus 로고
    • Serum leptin changes in epileptic patients who gain weight after therapy with valproic acid
    • Verrotti A, Basciani F, Morresi S, et al. Serum leptin changes in epileptic patients who gain weight after therapy with valproic acid. Neurology 1999;53(1):230-2
    • (1999) Neurology , vol.53 , Issue.1 , pp. 230-232
    • Verrotti, A.1    Basciani, F.2    Morresi, S.3
  • 17
    • 0034086861 scopus 로고    scopus 로고
    • Weight gain associated with valproate in childhood
    • Demir E, Aysun S. Weight gain associated with valproate in childhood. Pediatr Neurol 2000;22(5):361-4
    • (2000) Pediatr Neurol , vol.22 , Issue.5 , pp. 361-364
    • Demir, E.1    Aysun, S.2
  • 18
    • 0037310224 scopus 로고    scopus 로고
    • Valproic acid-associated weight gain in older children and teens with epilepsy
    • Wirrell EC. Valproic acid-associated weight gain in older children and teens with epilepsy. Pediatr Neurol 2003;28(2):126-9
    • (2003) Pediatr Neurol , vol.28 , Issue.2 , pp. 126-129
    • Wirrell, E.C.1
  • 19
    • 25144468830 scopus 로고    scopus 로고
    • Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up
    • Maggioni F, Ruffatti S, Dainese F, et al. Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up. J Headache Pain 2005;6(4): 322-4
    • (2005) J Headache Pain , vol.6 , Issue.4 , pp. 322-324
    • Maggioni, F.1    Ruffatti, S.2    Dainese, F.3
  • 21
    • 84862575407 scopus 로고    scopus 로고
    • Characterizing and understanding body weight patterns in patients treated with pregabalin
    • Cabrera J, Emir B, Dills D, et al. Characterizing and understanding body weight patterns in patients treated with pregabalin. Curr Med Res Opin 2012; 28(6):1027-37
    • (2012) Curr Med Res Opin , vol.28 , Issue.6 , pp. 1027-1037
    • Cabrera, J.1    Emir, B.2    Dills, D.3
  • 22
    • 0033595496 scopus 로고    scopus 로고
    • Positive and negative psychiatric effects of antiepileptic drugs in patients with seizure disorders
    • Ketter TA, Post RM, Theodore WH. Positive and negative psychiatric effects of antiepileptic drugs in patients with seizure disorders. Neurology 1999;53(5 Suppl 2): S53-67
    • (1999) Neurology , vol.53 , Issue.5 , pp. S53-67
    • Ketter, T.A.1    Post, R.M.2    Theodore, W.H.3
  • 23
    • 70449533094 scopus 로고    scopus 로고
    • Six months of postmarketing experience with adjunctive lacosamide in patients with pharmacoresistant focal epilepsy at a tertiary epilepsy center in Germany
    • Wehner T, Bauer S, Hamer HM, et al. Six months of postmarketing experience with adjunctive lacosamide in patients with pharmacoresistant focal epilepsy at a tertiary epilepsy center in Germany. Epilepsy Behav 2009;16(3):423-5
    • (2009) Epilepsy Behav , vol.16 , Issue.3 , pp. 423-425
    • Wehner, T.1    Bauer, S.2    Hamer, H.M.3
  • 24
    • 84872053451 scopus 로고    scopus 로고
    • Dramatic weight loss with rufinamide
    • Mourand I, Crespel A, Gelisse P. Dramatic weight loss with rufinamide. Epilepsia 2013; 54(1):e5-8
    • (2013) Epilepsia , vol.54 , Issue.1 , pp. e5-8
    • Mourand, I.1    Crespel, A.2    Gelisse, P.3
  • 25
    • 0033869417 scopus 로고    scopus 로고
    • Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin
    • Hogan RE, Bertrand ME, Deaton RL, Sommerville KW. Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin. Epilepsy Res 2000;41(1):23-8
    • (2000) Epilepsy Res , vol.41 , Issue.1 , pp. 23-28
    • Hogan, R.E.1    Bertrand, M.E.2    Deaton, R.L.3    Sommerville, K.W.4
  • 26
    • 0034884255 scopus 로고    scopus 로고
    • Oxcarbazepine in the treatment of epilepsy
    • Glauser TA. Oxcarbazepine in the treatment of epilepsy. Pharmacotherapy 2001;21(8): 904-19
    • (2001) Pharmacotherapy , vol.21 , Issue.8 , pp. 904-919
    • Glauser, T.A.1
  • 27
    • 0037305116 scopus 로고    scopus 로고
    • Lamotrigine versus valproate monotherapy-associated weight change in adolescents with epilepsy: Results from a post hoc analysis of a randomized, double-blind clinical trial
    • Biton V, Levisohn P, Hoyler S, et al. Lamotrigine versus valproate monotherapy-associated weight change in adolescents with epilepsy: results from a post hoc analysis of a randomized, double-blind clinical trial. J Child Neurol 2003;18(2):133-9
    • (2003) J Child Neurol , vol.18 , Issue.2 , pp. 133-139
    • Biton, V.1    Levisohn, P.2    Hoyler, S.3
  • 28
    • 0038094412 scopus 로고    scopus 로고
    • Higher androgens and weight gain with valproate compared with lamotrigine for epilepsy
    • Morrell MJ, Isojärvi J, Taylor AE, et al. Higher androgens and weight gain with valproate compared with lamotrigine for epilepsy. Epilepsy Res 2003;54(2-3):189-99
    • (2003) Epilepsy Res , vol.54 , Issue.2-3 , pp. 189-199
    • Morrell, M.J.1    Isojärvi, J.2    Taylor, A.E.3
  • 29
    • 85047700414 scopus 로고    scopus 로고
    • Impact of lamotrigine and lithium on weight in obese and nonobese patients with bipolar 1 disorder
    • Bowden CL, Calabrese JR, Ketter TA, et al. Impact of lamotrigine and lithium on weight in obese and nonobese patients with bipolar 1 disorder. Am J Psychiatry 2006; 163(7):1199-201
    • (2006) Am J Psychiatry , vol.163 , Issue.7 , pp. 1199-1201
    • Bowden, C.L.1    Calabrese, J.R.2    Ketter, T.A.3
  • 30
    • 33745835789 scopus 로고    scopus 로고
    • Effects of lamotrigine and lithium on body weight during maintenance treatment of bipolar i disorder
    • Sachs G, Bowden C, Calabrese JR, et al. Effects of lamotrigine and lithium on body weight during maintenance treatment of bipolar I disorder. Bipolar Disord 2006; 8(2):175-81
    • (2006) Bipolar Disord , vol.8 , Issue.2 , pp. 175-181
    • Sachs, G.1    Bowden, C.2    Calabrese, J.R.3
  • 31
    • 38449095961 scopus 로고    scopus 로고
    • Effectiveness and weight effects of open-label lamotrigine with and without concomitant psychotropic medications in patients with bipolar i disorder
    • Zarzar MN, Graham J, Roberts J, et al. Effectiveness and weight effects of open-label lamotrigine with and without concomitant psychotropic medications in patients with bipolar I disorder. MedGenMed 2007;9(2):41
    • (2007) MedGenMed , vol.9 , Issue.2 , pp. 41
    • Zarzar, M.N.1    Graham, J.2    Roberts, J.3
  • 32
    • 45149113072 scopus 로고    scopus 로고
    • Weight gain in bipolar disorder: Pharmacological treatment as a contributing factor
    • Torrent C, Amann B, Sánchez-Moreno J, et al. Weight gain in bipolar disorder: pharmacological treatment as a contributing factor. Acta Psychiatr Scand 2008;118(1): 4-18
    • (2008) Acta Psychiatr Scand , vol.118 , Issue.1 , pp. 4-18
    • Torrent, C.1    Amann, B.2    Sánchez-Moreno, J.3
  • 33
    • 67649159500 scopus 로고    scopus 로고
    • Lamotrigine in the treatment of binge-eating disorder with obesity: A randomized, placebo-controlled monotherapy trial
    • Guerdjikova AI, McElroy SL, Welge JA, et al. Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial. Int Clin Psychopharmacol 2009;24(3):150-8
    • (2009) Int Clin Psychopharmacol , vol.24 , Issue.3 , pp. 150-158
    • Guerdjikova, A.I.1    McElroy, S.L.2    Welge, J.A.3
  • 35
    • 0032787096 scopus 로고    scopus 로고
    • Review of controlled trials of Gabitril (tiagabine): A clinician's viewpoint
    • Loiseau P. Review of controlled trials of Gabitril (tiagabine): a clinician's viewpoint. Epilepsia 1999;40(S9):S14-19
    • (1999) Epilepsia , vol.40 , Issue.S9 , pp. S14-19
    • Loiseau, P.1
  • 36
    • 0345690127 scopus 로고    scopus 로고
    • Levetiracetam does not alter body weight: Analysis of randomized, controlled clinical trials
    • Gidal BE, Sheth RD, Magnus L, Herbeuval AF. Levetiracetam does not alter body weight: analysis of randomized, controlled clinical trials. Epilepsy Res 2003; 56(2-3):121-6
    • (2003) Epilepsy Res , vol.56 , Issue.2-3 , pp. 121-126
    • Gidal, B.E.1    Sheth, R.D.2    Magnus, L.3    Herbeuval, A.F.4
  • 37
    • 0142010595 scopus 로고    scopus 로고
    • Drug points: Weight loss associated with levetiracetam
    • Hadjikoutis S, Pickersgill TP, Smith PE. Drug points: weight loss associated with levetiracetam. BMJ 2003;327(7420):905
    • (2003) BMJ , vol.327 , Issue.7420 , pp. 905
    • Hadjikoutis, S.1    Pickersgill, T.P.2    Smith, P.E.3
  • 38
    • 38649105825 scopus 로고    scopus 로고
    • Dramatic weight loss with levetiracetam
    • Gelisse P, Juntas-Morales R, Genton P, et al. Dramatic weight loss with levetiracetam. Epilepsia 2008;49(2):308-15
    • (2008) Epilepsia , vol.49 , Issue.2 , pp. 308-315
    • Gelisse, P.1    Juntas-Morales, R.2    Genton, P.3
  • 39
    • 0032693665 scopus 로고    scopus 로고
    • Physical and psychological consequences of weight gain
    • Kawachi I. Physical and psychological consequences of weight gain. J Clin Psychiatry 1999;60(Suppl 21):5-9
    • (1999) J Clin Psychiatry , vol.60 , pp. 5-9
    • Kawachi, I.1
  • 40
    • 0036255430 scopus 로고    scopus 로고
    • Adolescent issues in epilepsy
    • Sheth R. Adolescent issues in epilepsy. J Child Neurol 2002;17(Sl2):S23-7
    • (2002) J Child Neurol , vol.17 , Issue.S12 , pp. S23-S27
    • Sheth, R.1
  • 41
    • 24744460124 scopus 로고    scopus 로고
    • Serum thyroid hormone balance and lipid profile in patients with epilepsy
    • Hamed SA, Hamed EA, Kandil MR, et al. Serum thyroid hormone balance and lipid profile in patients with epilepsy. Epilepsy Res 2005;66(1-3):173-83
    • (2005) Epilepsy Res , vol.66 , Issue.1-3 , pp. 173-183
    • Hamed, S.A.1    Hamed, E.A.2    Kandil, M.R.3
  • 42
    • 24744464425 scopus 로고    scopus 로고
    • The high atherosclerotic risk among epileptics: The atheroprotective role of multivitamins
    • Hamed SA, Nabeshima T. The high atherosclerotic risk among epileptics: the atheroprotective role of multivitamins. J Pharmacol Sci 2005;98(4):340-53
    • (2005) J Pharmacol Sci , vol.98 , Issue.4 , pp. 340-353
    • Hamed, S.A.1    Nabeshima, T.2
  • 43
    • 33745612500 scopus 로고    scopus 로고
    • Mortality and cardiac and vascular outcomes in extremely obese women
    • McTigue K, Larson JC, Valoski A, et al. Mortality and cardiac and vascular outcomes in extremely obese women. JAMA 2006; 296(1):79-86
    • (2006) JAMA , vol.296 , Issue.1 , pp. 79-86
    • McTigue, K.1    Larson, J.C.2    Valoski, A.3
  • 44
    • 33845480996 scopus 로고    scopus 로고
    • The reproductive conditions and lipid profile in females with epilepsy
    • Hamed SA, Hamed SA, Shokry M, et al. The reproductive conditions and lipid profile in females with epilepsy. Acta Neurol Scand 2007;115(1):12-27
    • (2007) Acta Neurol Scand , vol.115 , Issue.1 , pp. 12-27
    • Hamed, S.A.1    Hamed, S.A.2    Shokry, M.3
  • 45
    • 84918576899 scopus 로고    scopus 로고
    • Atherosclerosis in epilepsy: Its causes and implications
    • [Epub ahead of print]
    • Hamed SA. Atherosclerosis in epilepsy: its causes and implications. Epilepsy Behav 2014. [Epub ahead of print]
    • (2014) Epilepsy Behav
    • Hamed, S.A.1
  • 46
    • 31144456395 scopus 로고    scopus 로고
    • Serum insulin, leptin, and neuropeptide y levels in epileptic children treated with valproate
    • Aydin K, Serdaroglu A, Okuyaz C, et al. Serum insulin, leptin, and neuropeptide Y levels in epileptic children treated with valproate. J Child Neurol 2005;20(10): 848-51
    • (2005) J Child Neurol , vol.20 , Issue.10 , pp. 848-851
    • Aydin, K.1    Serdaroglu, A.2    Okuyaz, C.3
  • 47
    • 33745792226 scopus 로고    scopus 로고
    • Chronic valproic acid treatment triggers increased neuropeptide y expression and signaling in rat nucleus reticularis thalami
    • Brill J, Lee M, Zhao S, et al. Chronic valproic acid treatment triggers increased neuropeptide y expression and signaling in rat nucleus reticularis thalami. J Neurosci 2006;26(25):6813-22
    • (2006) J Neurosci , vol.26 , Issue.25 , pp. 6813-6822
    • Brill, J.1    Lee, M.2    Zhao, S.3
  • 48
    • 79960554651 scopus 로고    scopus 로고
    • Serum insulin, cortisol, leptin, neuropeptide Y, galanin and ghrelin levels in epileptic children receiving valproate
    • Cansu A, Serdaroglu A, Camurdan O, et al. Serum insulin, cortisol, leptin, neuropeptide Y, galanin and ghrelin levels in epileptic children receiving valproate. Horm Res Paediatr 2011;76(1):65-71
    • (2011) Horm Res Paediatr , vol.76 , Issue.1 , pp. 65-71
    • Cansu, A.1    Serdaroglu, A.2    Camurdan, O.3
  • 49
    • 0015701039 scopus 로고
    • Cholecystokinin decreases food intake in rats
    • Gibbs J, Young RC, Smith GP. Cholecystokinin decreases food intake in rats. J Comp Physiol Psychol 1973;84(3): 488-95
    • (1973) J Comp Physiol Psychol , vol.84 , Issue.3 , pp. 488-495
    • Gibbs, J.1    Young, R.C.2    Smith, G.P.3
  • 50
    • 0035843183 scopus 로고    scopus 로고
    • A role for ghrelin in the central regulation of feeding
    • Nakazato M, Murakami N, Date Y, et al. A role for ghrelin in the central regulation of feeding. Nature 2001;409(6817):194-8
    • (2001) Nature , vol.409 , Issue.6817 , pp. 194-198
    • Nakazato, M.1    Murakami, N.2    Date, Y.3
  • 51
    • 0033082380 scopus 로고    scopus 로고
    • From lesions to leptin: Hypothalamic control of food intake and body weight
    • Elmquist JK, Elias CF, Saper CB. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 1999; 22(2):221-32
    • (1999) Neuron , vol.22 , Issue.2 , pp. 221-232
    • Elmquist, J.K.1    Elias, C.F.2    Saper, C.B.3
  • 52
    • 0036177867 scopus 로고    scopus 로고
    • Control of energy homeostasis and insulin action by adipocyte hormones: Leptin, acylation stimulating protein and adiponectin
    • Havel PJ. Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein and adiponectin. Curr Opin Lipidol 2002;13(1): 51-9
    • (2002) Curr Opin Lipidol , vol.13 , Issue.1 , pp. 51-59
    • Havel, P.J.1
  • 53
    • 0026542355 scopus 로고
    • Peptides affect the intake of specific nutrients and the sympathetic nervous system
    • Bray G. Peptides affect the intake of specific nutrients and the sympathetic nervous system. Am J Clin Nutr 1992;55(1 Suppl): 265S-71S
    • (1992) Am J Clin Nutr , vol.55 , Issue.1 , pp. 265S-71S
    • Bray, G.1
  • 54
    • 0026795166 scopus 로고
    • Glucocorticoids are Required for Food Deprivation-Induced Increases in Hypothalamic Neuropeptide y Expression
    • Ponsalle P, Srivastava LS, Uht RM, White JD. Glucocorticoids are Required for Food Deprivation-Induced Increases in Hypothalamic Neuropeptide Y Expression. J Neuroendocrinol 1992;4(5):585-91
    • (1992) J Neuroendocrinol , vol.4 , Issue.5 , pp. 585-591
    • Ponsalle, P.1    Srivastava, L.S.2    Uht, R.M.3    White, J.D.4
  • 55
    • 0022873040 scopus 로고
    • Neuropeptide y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity
    • Stanley BG, Kyrkouli SE, Lampert S, Leibowitz SF. Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity. Peptides 1986;7(6):1189-92
    • (1986) Peptides , vol.7 , Issue.6 , pp. 1189-1192
    • Stanley, B.G.1    Kyrkouli, S.E.2    Lampert, S.3    Leibowitz, S.F.4
  • 56
    • 0030764741 scopus 로고    scopus 로고
    • Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
    • Ollmann MM, Wilson BD, Yang YK, et al. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 1997; 278(5335):135-8
    • (1997) Science , vol.278 , Issue.5335 , pp. 135-138
    • Ollmann, M.M.1    Wilson, B.D.2    Yang, Y.K.3
  • 57
    • 13344279395 scopus 로고    scopus 로고
    • A role for melanin-concentrating hormone in the central regulation of feeding behavior
    • Qu D, Ludwig DS, Gammeltoft S, et al. A role for melanin-concentrating hormone in the central regulation of feeding behavior. Nature 1996;380(6571):243-7
    • (1996) Nature , vol.380 , Issue.6571 , pp. 243-247
    • Qu, D.1    Ludwig, D.S.2    Gammeltoft, S.3
  • 58
    • 20244380014 scopus 로고    scopus 로고
    • Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    • Sakurai T, Amemiya A, Ishii M, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998;92(4):573-85
    • (1998) Cell , vol.92 , Issue.4 , pp. 573-585
    • Sakurai, T.1    Amemiya, A.2    Ishii, M.3
  • 59
    • 84896739675 scopus 로고    scopus 로고
    • The endocannabinoid system controls food intake via olfactory processes
    • Soria-Gomez E, Bellocchio L, Reguero L, et al. The endocannabinoid system controls food intake via olfactory processes. Nat Neurosci 2014;17(3):407-15
    • (2014) Nat Neurosci , vol.17 , Issue.3 , pp. 407-415
    • Soria-Gomez, E.1    Bellocchio, L.2    Reguero, L.3
  • 60
    • 0027253834 scopus 로고
    • Regulation of alpha-melanocyte-stimulating hormone release from hypothalamic neurons
    • Jegou S, Blasquez C, Delbende C, et al. Regulation of alpha-melanocyte-stimulating hormone release from hypothalamic neurons. Ann N Y Acad Sci 1993;680: 260-78
    • (1993) Ann N y Acad Sci , vol.680 , pp. 260-278
    • Jegou, S.1    Blasquez, C.2    Delbende, C.3
  • 61
    • 84877617600 scopus 로고    scopus 로고
    • Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in feeding- and reward-related brain areas of young OLETF rats
    • Armbruszt S, Abraham H, Figler M, et al. Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in feeding- and reward-related brain areas of young OLETF rats. J Chem Neuroanat 2013;50-51:75-84
    • (2013) J Chem Neuroanat , vol.50-51 , pp. 75-84
    • Armbruszt, S.1    Abraham, H.2    Figler, M.3
  • 62
    • 33746308184 scopus 로고    scopus 로고
    • The TRH neuron: A hypothalamic integrator of energy metabolism
    • Lechan RM, Fekete C. The TRH neuron: a hypothalamic integrator of energy metabolism. Prog Brain Res 2006;153: 209-35
    • (2006) Prog Brain Res , vol.153 , pp. 209-235
    • Lechan, R.M.1    Fekete, C.2
  • 63
    • 0023767089 scopus 로고
    • Effects of corticotropin-releasing factor on food intake and brown adipose tissue thermogenesis in rats
    • Arase K, York DA, Shimizu H, et al. Effects of corticotropin-releasing factor on food intake and brown adipose tissue thermogenesis in rats. Am J Physiol 1988; 255(3 Pt 1):E255-9
    • (1988) Am J Physiol , vol.255 , Issue.3 , pp. E255-E259
    • Arase, K.1    York, D.A.2    Shimizu, H.3
  • 64
    • 13344259300 scopus 로고    scopus 로고
    • Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
    • Chen H, Charlat O, Tartaglia LA, et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996;84(3):491-5
    • (1996) Cell , vol.84 , Issue.3 , pp. 491-495
    • Chen, H.1    Charlat, O.2    Tartaglia, L.A.3
  • 65
    • 84908632199 scopus 로고    scopus 로고
    • Coinfusion of low-dose GLP-1 and glucagon in man results in a reduction in food intake
    • Cegla J, Troke RC, Jones B, et al. Coinfusion of low-dose GLP-1 and glucagon in man results in a reduction in food intake. Diabetes 2014;63(11):3711-20
    • (2014) Diabetes , vol.63 , Issue.11 , pp. 3711-3720
    • Cegla, J.1    Troke, R.C.2    Jones, B.3
  • 66
    • 1642263164 scopus 로고    scopus 로고
    • Hypothalamic control of energy balance
    • Harrold JA. Hypothalamic control of energy balance. Curr Drug Targets 2004;5(3): 207-19
    • (2004) Curr Drug Targets , vol.5 , Issue.3 , pp. 207-219
    • Harrold, J.A.1
  • 67
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spiegelman BM, Flier JS. Obesity and the regulation of energy balance. Cell 2001; 104(4):531-43
    • (2001) Cell , vol.104 , Issue.4 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 68
    • 0022149006 scopus 로고
    • Afferent axons in abdominal vagus mediate the satiety effect of cholycystokinin in rats
    • Smith GP, Jerome E, Norgren R. Afferent axons in abdominal vagus mediate the satiety effect of cholycystokinin in rats. Am J Physiol 1985;249(5 Pt 2):R638-41
    • (1985) Am J Physiol , vol.249 , Issue.5 , pp. R638-R641
    • Smith, G.P.1    Jerome, E.2    Norgren, R.3
  • 69
    • 0036168190 scopus 로고    scopus 로고
    • Characterization of short isoforms of the leptin receptor in rat cerebral microvessels and of brain uptake of leptin in mouse models of obesity
    • Hileman SM, Pierroz DD, Masuzaki H, et al. Characterization of short isoforms of the leptin receptor in rat cerebral microvessels and of brain uptake of leptin in mouse models of obesity. Endocrinology 2002;143(3):775-83
    • (2002) Endocrinology , vol.143 , Issue.3 , pp. 775-783
    • Hileman, S.M.1    Pierroz, D.D.2    Masuzaki, H.3
  • 70
    • 0028284647 scopus 로고
    • Impaired insulin-induced sympathetic neural activation and vasodilation in skeletal muscle in obese humans
    • Vollenweider P, Randin D, Tappy L, et al. Impaired insulin-induced sympathetic neural activation and vasodilation in skeletal muscle in obese humans. J Clin Invest 1994;93(6):2365-71
    • (1994) J Clin Invest , vol.93 , Issue.6 , pp. 2365-2371
    • Vollenweider, P.1    Randin, D.2    Tappy, L.3
  • 71
    • 0030876805 scopus 로고    scopus 로고
    • Receptor-mediated regional sympathetic nerve activation by leptin
    • Haynes WG, Morgan DA, Walsh SA, et al. Receptor-mediated regional sympathetic nerve activation by leptin. J Clin Invest 1997;100(2):270-8
    • (1997) J Clin Invest , vol.100 , Issue.2 , pp. 270-278
    • Haynes, W.G.1    Morgan, D.A.2    Walsh, S.A.3
  • 72
    • 0035942777 scopus 로고    scopus 로고
    • Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
    • Cowley MA, Smart JL, Rubinstein M, et al. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 2001;411(6836): 480-4
    • (2001) Nature , vol.411 , Issue.6836 , pp. 480-484
    • Cowley, M.A.1    Smart, J.L.2    Rubinstein, M.3
  • 73
    • 0037288941 scopus 로고    scopus 로고
    • Insulin and leptin revisited: Adiposity signals with overlapping physiological and intracellular signaling capabilities
    • Niswender KD, Schwartz MW. Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities. Front Neuroendocrinol 2003;24(1):1-10
    • (2003) Front Neuroendocrinol , vol.24 , Issue.1 , pp. 1-10
    • Niswender, K.D.1    Schwartz, M.W.2
  • 74
    • 33745576798 scopus 로고    scopus 로고
    • Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
    • Kim MS, Pak YK, Jang PG, et al. Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis. Nat Neurosci 2006;9(7):901-6
    • (2006) Nat Neurosci , vol.9 , Issue.7 , pp. 901-906
    • Kim, M.S.1    Pak, Y.K.2    Jang, P.G.3
  • 75
    • 0037410414 scopus 로고    scopus 로고
    • Leptin in the CNS: Much more than a satiety signal
    • Harvey J, Ashford ML. Leptin in the CNS: much more than a satiety signal. Neuropharmacology 2003;44(7):845-54
    • (2003) Neuropharmacology , vol.44 , Issue.7 , pp. 845-854
    • Harvey, J.1    Ashford, M.L.2
  • 76
    • 0027249346 scopus 로고
    • Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI2-kinase
    • Kanai F, Ito K, Todaka M, et al. Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI2-kinase. Biochem Biophys Res Commun 1993; 195(2):762-8
    • (1993) Biochem Biophys Res Commun , vol.195 , Issue.2 , pp. 762-768
    • Kanai, F.1    Ito, K.2    Todaka, M.3
  • 77
    • 0030737573 scopus 로고    scopus 로고
    • Effects of leptin on insulin sensitivity in normal rats
    • Sivitz WI, Walsh SA, Morgan DA, et al. Effects of leptin on insulin sensitivity in normal rats. Endocrinology 1997;138(8): 3395-401
    • (1997) Endocrinology , vol.138 , Issue.8 , pp. 3395-3401
    • Sivitz, W.I.1    Walsh, S.A.2    Morgan, D.A.3
  • 78
    • 0031698546 scopus 로고    scopus 로고
    • Leptin expression in adipose tissue from obese humans: Depot-specific regulation by insulin and dexamethasone
    • Russell CD, Petersen RN, Rao SP, et al. Leptin expression in adipose tissue from obese humans: depot-specific regulation by insulin and dexamethasone. Am J Physiol 1998;275(3 Pt 1):E507-15
    • (1998) Am J Physiol , vol.275 , Issue.3 , pp. E507-E515
    • Russell, C.D.1    Petersen, R.N.2    Rao, S.P.3
  • 79
    • 0032913312 scopus 로고    scopus 로고
    • Leptin enhances glycogen storage in hepatocytes by inhibition of phosphorylase and exerts an additive effect with insulin
    • Aiston S, Agius L. Leptin enhances glycogen storage in hepatocytes by inhibition of phosphorylase and exerts an additive effect with insulin. Diabetes 1999;48(1):15-20
    • (1999) Diabetes , vol.48 , Issue.1 , pp. 15-20
    • Aiston, S.1    Agius, L.2
  • 80
    • 0029860791 scopus 로고    scopus 로고
    • Modulation of insulin activities by leptin
    • Cohen B, Novick D, Rubinstein M. Modulation of insulin activities by leptin. Science 1996;274(5290):1185-8
    • (1996) Science , vol.274 , Issue.5290 , pp. 1185-1188
    • Cohen, B.1    Novick, D.2    Rubinstein, M.3
  • 81
    • 0035125097 scopus 로고    scopus 로고
    • Physiological increase in plasma leptin inhibits insulin secretion in vivo
    • Cases JA, Gabriely I, Ma XH, et al. Physiological increase in plasma leptin inhibits insulin secretion in vivo. Diabetes 2001;50(2):348-52
    • (2001) Diabetes , vol.50 , Issue.2 , pp. 348-352
    • Cases, J.A.1    Gabriely, I.2    Ma, X.H.3
  • 82
    • 0036182137 scopus 로고    scopus 로고
    • Lipotoxic diseases
    • Unger RH. Lipotoxic diseases. Annu Rev Med 2002;53:319-36
    • (2002) Annu Rev Med , vol.53 , pp. 319-336
    • Unger, R.H.1
  • 83
    • 0037115192 scopus 로고    scopus 로고
    • Leptin inhibits epileptiform-like activity in rat hippocampal neurons via PI3-kinase-driven activation of BK channels
    • Shanley LJ, O'Malley D, Irving AJ, et al. Leptin inhibits epileptiform-like activity in rat hippocampal neurons via PI3-kinase-driven activation of BK channels. J Physiol 2002;545(Pt 3):933-44
    • (2002) J Physiol , vol.545 , pp. 933-944
    • Shanley, L.J.1    O'malley, D.2    Irving, A.J.3
  • 84
    • 0033944152 scopus 로고    scopus 로고
    • Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats
    • Spanswick D, Smith MA, Mirshamsi S, et al. Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats. Nat Neurosci 2000;3(8): 757-8
    • (2000) Nat Neurosci , vol.3 , Issue.8 , pp. 757-758
    • Spanswick, D.1    Smith, M.A.2    Mirshamsi, S.3
  • 85
    • 0037355388 scopus 로고    scopus 로고
    • A putative relationship between valproic acid and polycystic ovarian syndrome: Implications for treatment of women with seizure and bipolar disorders
    • Joffe H, Hall JE, Cohen LS, et al. A putative relationship between valproic acid and polycystic ovarian syndrome: implications for treatment of women with seizure and bipolar disorders. Harv Rev Psychiatry 2003;11(2):99-108
    • (2003) Harv Rev Psychiatry , vol.11 , Issue.2 , pp. 99-108
    • Joffe, H.1    Hall, J.E.2    Cohen, L.S.3
  • 86
    • 0031749077 scopus 로고    scopus 로고
    • Valproate, lamotrigine, and insulin-mediated risks in women with epilepsy
    • Isojärvi JI, Rättyä J, Myllylä VV, et al. Valproate, lamotrigine, and insulin-mediated risks in women with epilepsy. Ann Neurol 1998;43(4):446-51
    • (1998) Ann Neurol , vol.43 , Issue.4 , pp. 446-451
    • Isojärvi, J.I.1    Rättyä, J.2    Myllylä, V.V.3
  • 87
    • 33847385855 scopus 로고    scopus 로고
    • Valproate, weight gain and carbohydrate craving: A gender study
    • El-Khatib F, Rauchenzauner M, Lechleitner M, et al. Valproate, weight gain and carbohydrate craving: a gender study. Seizure 2007;16(3):226-32
    • (2007) Seizure , vol.16 , Issue.3 , pp. 226-232
    • El-Khatib, F.1    Rauchenzauner, M.2    Lechleitner, M.3
  • 88
    • 0343445201 scopus 로고    scopus 로고
    • The effects of valproate, carbamazepine and oxcarbamazepine on growth and sexual maturation in girls with epilepsy
    • Rättyä J, Vainionpää L, Knip M, et al. The effects of valproate, carbamazepine and oxcarbamazepine on growth and sexual maturation in girls with epilepsy. Pediatrics 1999;103(3):588-93
    • (1999) Pediatrics , vol.103 , Issue.3 , pp. 588-593
    • Rättyä, J.1    Vainionpää, L.2    Knip, M.3
  • 89
    • 0029884009 scopus 로고    scopus 로고
    • Obesity and endocrine disorders in women taking valproate for epilepsy
    • Isojärvi JI, Laatikainen TJ, Knip M, et al. Obesity and endocrine disorders in women taking valproate for epilepsy. Ann Neurol 1996;39(5):579-84
    • (1996) Ann Neurol , vol.39 , Issue.5 , pp. 579-584
    • Isojärvi, J.I.1    Laatikainen, T.J.2    Knip, M.3
  • 90
    • 0031046986 scopus 로고    scopus 로고
    • Elevated free fatty acid concentrations in lipemic sera reduce protein binding of valproic acid significantly more than phenytoin
    • Dasgupta A, Crossey MJ. Elevated free fatty acid concentrations in lipemic sera reduce protein binding of valproic acid significantly more than phenytoin. Am J Med Sci 1996; 313(2):75-9
    • (1996) Am J Med Sci , vol.313 , Issue.2 , pp. 75-79
    • Dasgupta, A.1    Crossey, M.J.2
  • 91
    • 33645064880 scopus 로고    scopus 로고
    • Leptin, ghrelin and adiponectin in epileptic patients treated with valproic acid
    • Greco R, Latini G, Chiarelli F, et al. Leptin, ghrelin and adiponectin in epileptic patients treated with valproic acid. Neurology 2005;65(11):1808-9
    • (2005) Neurology , vol.65 , Issue.11 , pp. 1808-1809
    • Greco, R.1    Latini, G.2    Chiarelli, F.3
  • 92
    • 12444255208 scopus 로고    scopus 로고
    • Trace elements and electrolytes homeostasis and their relation to antioxidant enzyme activity in brain hyperexcitability of epileptic patients
    • Hamed SA, Abdellah MM. Trace elements and electrolytes homeostasis and their relation to antioxidant enzyme activity in brain hyperexcitability of epileptic patients. J Pharmacol Sci 2004;96(4):349-59
    • (2004) J Pharmacol Sci , vol.96 , Issue.4 , pp. 349-359
    • Hamed, S.A.1    Abdellah, M.M.2
  • 93
    • 12444315074 scopus 로고    scopus 로고
    • Blood levels of trace elements, electrolytes, and oxidative stress/antioxidant systems in epileptic patients
    • Hamed SA, Abdellah MM, El-Melegy N. Blood levels of trace elements, electrolytes, and oxidative stress/antioxidant systems in epileptic patients. J Pharmacol Sci 2004; 96(4):465-73
    • (2004) J Pharmacol Sci , vol.96 , Issue.4 , pp. 465-473
    • Hamed, S.A.1    Abdellah, M.M.2    El-Melegy, N.3
  • 94
    • 34247528209 scopus 로고    scopus 로고
    • Vascular risk factors and oxidative stress as independent predictors of asymptomatic atherosclerosis in Adult patients with epilepsy
    • Hamed SA, Hamed EA, Hamdy R, Nabeshima T. Vascular risk factors and oxidative stress as independent predictors of asymptomatic atherosclerosis in Adult patients with epilepsy. Epilepsy Res 2007; 74(2-3):183-92
    • (2007) Epilepsy Res , vol.74 , Issue.2-3 , pp. 183-192
    • Hamed, S.A.1    Hamed, E.A.2    Hamdy, R.3    Nabeshima, T.4
  • 95
    • 33748677979 scopus 로고    scopus 로고
    • Characterization of insulin secretion in valproate-treated patients with epilepsy
    • Pylvänen V, Pakarinen A, Knip M, Isojärvi J. Characterization of insulin secretion in valproate-treated patients with epilepsy. Epilepsia 2006;47(9):1460-4
    • (2006) Epilepsia , vol.47 , Issue.9 , pp. 1460-1464
    • Pylvänen, V.1    Pakarinen, A.2    Knip, M.3    Isojärvi, J.4
  • 96
    • 84888002921 scopus 로고    scopus 로고
    • The effects of topiramate and valproate therapy on insulin, c-peptide, leptin, neuropeptide Y, adiponectin, visfatin, and resistin levels in children with epilepsy
    • Sonmez FM, Zaman D, Aksoy A, et al. The effects of topiramate and valproate therapy on insulin, c-peptide, leptin, neuropeptide Y, adiponectin, visfatin, and resistin levels in children with epilepsy. Seizure 2013;22(10): 856-61
    • (2013) Seizure , vol.22 , Issue.10 , pp. 856-861
    • Sonmez, F.M.1    Zaman, D.2    Aksoy, A.3
  • 97
    • 0345291177 scopus 로고    scopus 로고
    • Valproate-induced hyperandrogenism during pubertal maturation in girls with epilepsy
    • Vainionpää LK, Rättyä J, Knip M, et al. Valproate-induced hyperandrogenism during pubertal maturation in girls with epilepsy. Ann Neurol 1999;45(4):444-50
    • (1999) Ann Neurol , vol.45 , Issue.4 , pp. 444-450
    • Vainionpää, L.K.1    Rättyä, J.2    Knip, M.3
  • 98
    • 84863724282 scopus 로고    scopus 로고
    • Plasma leptin, neuropeptide Y, ghrelin, and adiponectin levels and carotid artery intima media thickness in epileptic children treated with valproate
    • Tokgoz H, Aydin K, Oran B, Kiyici A. Plasma leptin, neuropeptide Y, ghrelin, and adiponectin levels and carotid artery intima media thickness in epileptic children treated with valproate. Childs Nerv Syst 2012; 28(7):1049-53
    • (2012) Childs Nerv Syst , vol.28 , Issue.7 , pp. 1049-1053
    • Tokgoz, H.1    Aydin, K.2    Oran, B.3    Kiyici, A.4
  • 99
    • 75649084560 scopus 로고    scopus 로고
    • Ghrelin levels are reduced in prepubertal epileptic children under treatment with carbamazepine or valproic acid
    • Prodam F, Bellone S, Casara G, et al. Ghrelin levels are reduced in prepubertal epileptic children under treatment with carbamazepine or valproic acid. Epilepsia 2010;51(2):312-15
    • (2010) Epilepsia , vol.51 , Issue.2 , pp. 312-315
    • Prodam, F.1    Bellone, S.2    Casara, G.3
  • 100
    • 84907355133 scopus 로고    scopus 로고
    • Serum, urine, and saliva levels of ghrelin and obestatin pre- and post-treatment in pediatric epilepsy
    • Taskin E, Atli B, Kiliç M, et al. Serum, urine, and saliva levels of ghrelin and obestatin pre- and post-treatment in pediatric epilepsy. Pediatr Neurol 2014; 51(3):365-9
    • (2014) Pediatr Neurol , vol.51 , Issue.3 , pp. 365-369
    • Taskin, E.1    Atli, B.2    Kiliç, M.3
  • 101
    • 2342478003 scopus 로고    scopus 로고
    • Obesity and plasma concentrations of alpha-tocopherol and beta-carotene in epileptic girls treated with valproate
    • Verrotti A, Greco R, Latini G, et al. Obesity and plasma concentrations of alpha-tocopherol and beta-carotene in epileptic girls treated with valproate. Neuroendocrinology 2014;79(3):157-62
    • (2014) Neuroendocrinology , vol.79 , Issue.3 , pp. 157-162
    • Verrotti, A.1    Greco, R.2    Latini, G.3
  • 102
    • 2142714501 scopus 로고    scopus 로고
    • Valproate therapy and nonalcoholic fatty liver disease
    • Luef GJ, Waldmann M, Sturm W, et al. Valproate therapy and nonalcoholic fatty liver disease. Ann Neurol 2004;55(5): 729-32
    • (2004) Ann Neurol , vol.55 , Issue.5 , pp. 729-732
    • Luef, G.J.1    Waldmann, M.2    Sturm, W.3
  • 103
    • 0026740783 scopus 로고
    • Metabolic changes during treatment with valproate in humans: Implication for untoward weight gain
    • Breum L, Astrup A, Gram L, et al. Metabolic changes during treatment with valproate in humans: implication for untoward weight gain. Metabolism 1992; 41(6):666-70
    • (1992) Metabolism , vol.41 , Issue.6 , pp. 666-670
    • Breum, L.1    Astrup, A.2    Gram, L.3
  • 104
    • 0019134448 scopus 로고
    • GABA and glutamate: Possible metabolic intermediaries involved in the hypothalamic regulation of food intake
    • Meeker RB, Myers RD. GABA and glutamate: possible metabolic intermediaries involved in the hypothalamic regulation of food intake. Brain Res Bull 1980;5:253-9
    • (1980) Brain Res Bull , vol.5 , pp. 253-259
    • Meeker, R.B.1    Myers, R.D.2
  • 105
    • 0041429418 scopus 로고    scopus 로고
    • Valproic acid modulates islet cell insulin secretion: A possible mechanism of weight gain in epilepsy patients
    • Luef GJ, Lechleitner M, Bauer G, et al. Valproic acid modulates islet cell insulin secretion: a possible mechanism of weight gain in epilepsy patients. Epilepsy Res 2003; 55(1-2):53-8
    • (2003) Epilepsy Res , vol.55 , Issue.1-2 , pp. 53-58
    • Luef, G.J.1    Lechleitner, M.2    Bauer, G.3
  • 106
    • 0034257051 scopus 로고    scopus 로고
    • Mechanism of action of Valproate: A commentary
    • Johannessen CU. Mechanism of action of Valproate: a commentary. Neurochem Int 2000;37(2-3):103-10
    • (2000) Neurochem Int , vol.37 , Issue.2-3 , pp. 103-110
    • Johannessen, C.U.1
  • 107
    • 0027376186 scopus 로고
    • Valproate and palmitate binding to serum albumin in valproate-treated patients: Relation to obesity
    • Vorum H, Gram L, Honore B. Valproate and palmitate binding to serum albumin in valproate-treated patients: relation to obesity. Epilepsy Res 1993;16(1):55-64
    • (1993) Epilepsy Res , vol.16 , Issue.1 , pp. 55-64
    • Vorum, H.1    Gram, L.2    Honore, B.3
  • 108
    • 0034090489 scopus 로고    scopus 로고
    • Fatty acids and insulin secretion
    • Grill V, Qvigstad E. Fatty acids and insulin secretion. Br J Nutr 2000;83(Suppl 1): S79-84
    • (2000) Br J Nutr , vol.83 , pp. S79-84
    • Grill, V.1    Qvigstad, E.2
  • 109
    • 0036092239 scopus 로고    scopus 로고
    • Banting lecture 2001: Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
    • MacGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002;51(1):7-18
    • (2002) Diabetes , vol.51 , Issue.1 , pp. 7-18
    • Macgarry, J.D.1
  • 110
    • 0033007561 scopus 로고    scopus 로고
    • Rapid impairment of skeletal muscle glucose transport/phosphorylation by free fatty acids in humans
    • Roden M, Krssak M, Stingl H, et al. Rapid impairment of skeletal muscle glucose transport/phosphorylation by free fatty acids in humans. Diabetes 1999;48(2):358-64
    • (1999) Diabetes , vol.48 , Issue.2 , pp. 358-364
    • Roden, M.1    Krssak, M.2    Stingl, H.3
  • 111
    • 0035339721 scopus 로고    scopus 로고
    • Effects of free fatty acids on beta-cell functions: A possible involvement of peroxisome proliferator-activated receptors alpha or pancreatic/duodenal home box
    • Yoshikawa H, Tajiri Y, Sako Y, et al. Effects of free fatty acids on beta-cell functions: a possible involvement of peroxisome proliferator-activated receptors alpha or pancreatic/duodenal home box. Metabolism 2001;50(5):613-18
    • (2001) Metabolism , vol.50 , Issue.5 , pp. 613-618
    • Yoshikawa, H.1    Tajiri, Y.2    Sako, Y.3
  • 112
    • 0033834685 scopus 로고    scopus 로고
    • Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion
    • Shi Y, Kanaani J, Menard-Rose V, et al. Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion. Am J Physiol Endocrinol Metab 2000;279(3):E684-94
    • (2000) Am J Physiol Endocrinol Metab , vol.279 , Issue.3 , pp. E684-E694
    • Shi, Y.1    Kanaani, J.2    Menard-Rose, V.3
  • 113
    • 33747448092 scopus 로고    scopus 로고
    • Immunogold study of effects of prenatal exposure to lipopolysaccharide and/or valproic acid on the rat blood-brain barrier vessels
    • Vorbrodt AW, Dobrogowska DH, Kozlowski PB, et al. Immunogold study of effects of prenatal exposure to lipopolysaccharide and/or valproic acid on the rat blood-brain barrier vessels. J Neurocytol 2005;34(6):435-46
    • (2005) J Neurocytol , vol.34 , Issue.6 , pp. 435-446
    • Vorbrodt, A.W.1    Dobrogowska, D.H.2    Kozlowski, P.B.3
  • 114
    • 0033457289 scopus 로고    scopus 로고
    • Changes in leptin and insulin composition in obese children during a weight reduction program
    • Reiterer EE, Sudi KM, Mayer A, et al. Changes in leptin and insulin composition in obese children during a weight reduction program. J Pediatr Endocrinol Metab 1999; 12(6):853-62
    • (1999) J Pediatr Endocrinol Metab , vol.12 , Issue.6 , pp. 853-862
    • Reiterer, E.E.1    Sudi, K.M.2    Mayer, A.3
  • 115
    • 0842334582 scopus 로고    scopus 로고
    • Valproate potentiates androgen biosynthesis in human ovarian theca cells
    • Nelson-DeGrave VL, Wickenheisser JK, Cockrell JE, et al. Valproate potentiates androgen biosynthesis in human ovarian theca cells. Endocrinology 2004;145(2): 799-808
    • (2004) Endocrinology , vol.145 , Issue.2 , pp. 799-808
    • Nelson-Degrave, V.L.1    Wickenheisser, J.K.2    Cockrell, J.E.3
  • 116
    • 9444252987 scopus 로고    scopus 로고
    • Valproic acid inhibits leptin secretion and reduces leptin messenger ribonucleic acid levels in adipocytes
    • Lagace DC, Mcleod RS, Nachtigal MW. Valproic acid inhibits leptin secretion and reduces leptin messenger ribonucleic acid levels in adipocytes. Endocrinology 2004; 145(12):5493-503
    • (2004) Endocrinology , vol.145 , Issue.12 , pp. 5493-5503
    • Lagace, D.C.1    McLeod, R.S.2    Nachtigal, M.W.3
  • 117
    • 0034051012 scopus 로고    scopus 로고
    • Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusion
    • Nisoli E, Carruba MO, Tonello C, et al. Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusion. Diabetes 2000;49(3):319-24
    • (2000) Diabetes , vol.49 , Issue.3 , pp. 319-324
    • Nisoli, E.1    Carruba, M.O.2    Tonello, C.3
  • 119
    • 0025740492 scopus 로고
    • Weight gain, increased appetite, and excessive food intake induced by carbamazepine
    • Lampl Y, Eshel Y, Rapaport A, Sarova-Pinhas I. Weight gain, increased appetite, and excessive food intake induced by carbamazepine. Clin Neuropharmacol 1991;14(3):251-5
    • (1991) Clin Neuropharmacol , vol.14 , Issue.3 , pp. 251-255
    • Lampl, Y.1    Eshel, Y.2    Rapaport, A.3    Sarova-Pinhas, I.4
  • 121
    • 68849097337 scopus 로고    scopus 로고
    • The effect of carbamazepine treatment on serum leptin levels
    • Uludag IF, Kulu U, Sener U, et al. The effect of carbamazepine treatment on serum leptin levels. Epilepsy Res 2009;86(1):48-53
    • (2009) Epilepsy Res , vol.86 , Issue.1 , pp. 48-53
    • Uludag, I.F.1    Kulu, U.2    Sener, U.3
  • 122
    • 0031405115 scopus 로고    scopus 로고
    • Changes in body weight with chronic, high-dose gabapentin therapy
    • DeToledo JC, Toledo C, DeCerce J, Ramsay RE. Changes in body weight with chronic, high-dose gabapentin therapy. Ther Drug Monit 1997;19(4):394-6
    • (1997) Ther Drug Monit , vol.19 , Issue.4 , pp. 394-396
    • Detoledo, J.C.1    Toledo, C.2    Decerce, J.3    Ramsay, R.E.4
  • 123
    • 79960138602 scopus 로고    scopus 로고
    • Adjunctive pregabalin for uncontrolled partial-onset seizures: Findings from a prospective audit
    • Stephen LJ, Parker P, Kelly K, et al. Adjunctive pregabalin for uncontrolled partial-onset seizures: findings from a prospective audit. Acta Neurol Scand 2011; 124(2):142-5
    • (2011) Acta Neurol Scand , vol.124 , Issue.2 , pp. 142-145
    • Stephen, L.J.1    Parker, P.2    Kelly, K.3
  • 124
    • 0034128399 scopus 로고    scopus 로고
    • Open-label adjunctive topiramate in the treatment of bipolar disorders
    • McElroy SL, Suppes T, Keck PE, et al. Open-label adjunctive topiramate in the treatment of bipolar disorders. Biol Psychiatry 2000;47(12):1025-33
    • (2000) Biol Psychiatry , vol.47 , Issue.12 , pp. 1025-1033
    • McElroy, S.L.1    Suppes, T.2    Keck, P.E.3
  • 125
    • 0034128353 scopus 로고    scopus 로고
    • Topiramate as add-on therapy: Pooled analysis of randomized controlled trials in adults
    • Reife R, Pledger G, Wu SC. Topiramate as add-on therapy: pooled analysis of randomized controlled trials in adults. Epilepsia 2000;41(Suppl 1):S66-71
    • (2000) Epilepsia , vol.41 , pp. S66-71
    • Reife, R.1    Pledger, G.2    Wu, S.C.3
  • 126
    • 42449091913 scopus 로고    scopus 로고
    • Topiramate, nutrition and weight change: A prospective study
    • Klein KM, Theisen F, Knake S, et al. Topiramate, nutrition and weight change: a prospective study. J Neurol Neurosurg Psychiatry 2008;79(5):590-3
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , Issue.5 , pp. 590-593
    • Klein, K.M.1    Theisen, F.2    Knake, S.3
  • 127
    • 77954874909 scopus 로고    scopus 로고
    • Weight reducing and metabolic effects of topiramate in patients with migraine-an observational study
    • Schütt M, Brinkhoff J, Drenckhan M, et al. Weight reducing and metabolic effects of topiramate in patients with migraine-an observational study. Exp Clin Endocrinol Diabetes 2010;118(7):449-52
    • (2010) Exp Clin Endocrinol Diabetes , vol.118 , Issue.7 , pp. 449-452
    • Schütt, M.1    Brinkhoff, J.2    Drenckhan, M.3
  • 128
    • 84904874501 scopus 로고    scopus 로고
    • The effect of topiramate on body weight and ghrelin, leptin, and neuropeptide-Y levels of prepubertal children with epilepsy
    • Ozcelik AA, Serdaroglu A, Bideci A, et al. The effect of topiramate on body weight and ghrelin, leptin, and neuropeptide-Y levels of prepubertal children with epilepsy. Pediatr Neurol 2014;51(2):220-4
    • (2014) Pediatr Neurol , vol.51 , Issue.2 , pp. 220-224
    • Ozcelik, A.A.1    Serdaroglu, A.2    Bideci, A.3
  • 129
    • 28944433610 scopus 로고    scopus 로고
    • Topiramate treatment in bulimia nervosa patients: A randomized, double-blind, placebo-controlled trial
    • Nickel C, Tritt K, Muehlbacher M, et al. Topiramate treatment in bulimia nervosa patients: a randomized, double-blind, placebo-controlled trial. Int J Eat Disord 2005;38(4):295-300
    • (2005) Int J Eat Disord , vol.38 , Issue.4 , pp. 295-300
    • Nickel, C.1    Tritt, K.2    Muehlbacher, M.3
  • 130
    • 26844441138 scopus 로고    scopus 로고
    • Add-on topiramate reduces weight in overweight patients with affective disorders: A clinical case series
    • Kirov G, Tredget J. Add-on topiramate reduces weight in overweight patients with affective disorders: a clinical case series. BMC Psychiatry 2005;5:19
    • (2005) BMC Psychiatry , vol.5 , pp. 19
    • Kirov, G.1    Tredget, J.2
  • 131
    • 84873080917 scopus 로고    scopus 로고
    • Effect of topiramate on weight gain in patients receiving atypical antipsychotic agents
    • Mahmood S, Booker I, Huang J, Coleman CI. Effect of topiramate on weight gain in patients receiving atypical antipsychotic agents. J Clin Psychopharmacol 2013;33(1):90-4
    • (2013) J Clin Psychopharmacol , vol.33 , Issue.1 , pp. 90-94
    • Mahmood, S.1    Booker, I.2    Huang, J.3    Coleman, C.I.4
  • 132
    • 8344272013 scopus 로고    scopus 로고
    • A randomized double-blind placebo-controlled study of the long-term efficacy and safety of topiramate in the treatment of obese subjects
    • Wilding J, Van Gaal L, Rissanen A, OBES-002 Study Group. A randomized double-blind placebo-controlled study of the long-term efficacy and safety of topiramate in the treatment of obese subjects. Int J Obes Relat Metab Disord 2004;28(11): 1399-410
    • (2004) Int J Obes Relat Metab Disord , vol.28 , Issue.11 , pp. 1399-1410
    • Wilding, J.1    Van Gaal, L.2    Rissanen, A.3
  • 133
    • 0033781367 scopus 로고    scopus 로고
    • Influence of topiramate in the regulation of energy balance
    • Richard D, Ferland J, Lanlonde J, et al. Influence of topiramate in the regulation of energy balance. Nutrition 2000;16(10): 961-6
    • (2000) Nutrition , vol.16 , Issue.10 , pp. 961-966
    • Richard, D.1    Ferland, J.2    Lanlonde, J.3
  • 134
    • 84875854090 scopus 로고    scopus 로고
    • Changes in cardiovascular risk associated with phentermine and topiramate extended-release in participants with comorbidities and a body mass index 27 kg/m(2)
    • Davidson MH, Tonstad S, Oparil S, et al. Changes in cardiovascular risk associated with phentermine and topiramate extended-release in participants with comorbidities and a body mass index 27 kg/m(2). Am J Cardiol 2013;111(8): 1131-8
    • (2013) Am J Cardiol , vol.111 , Issue.8 , pp. 1131-1138
    • Davidson, M.H.1    Tonstad, S.2    Oparil, S.3
  • 135
    • 1642565342 scopus 로고    scopus 로고
    • Additive effects of leptin and topiramate in reducing fat deposition in lean and obese ob/ob mice
    • Lalonde J, Samson P, Poulin S, et al. Additive effects of leptin and topiramate in reducing fat deposition in lean and obese ob/ob mice. Physiol Behav 2004;80(4): 415-20
    • (2004) Physiol Behav , vol.80 , Issue.4 , pp. 415-420
    • Lalonde, J.1    Samson, P.2    Poulin, S.3
  • 136
    • 0034576649 scopus 로고    scopus 로고
    • Topiramate reduces energy and fat gains in lean (Fa/?) and obese (fa/fa) Zucker rats
    • Picard F, Deshaies Y, Lalonde J, et al. Topiramate reduces energy and fat gains in lean (Fa/?) and obese (fa/fa) Zucker rats. Obes Res 2000;8(9):656-63
    • (2000) Obes Res , vol.8 , Issue.9 , pp. 656-663
    • Picard, F.1    Deshaies, Y.2    Lalonde, J.3
  • 137
    • 16644400954 scopus 로고    scopus 로고
    • Topiramate: Long-term maintenance of weight loss induced by a low-calorie diet in obese subjects
    • Astrup A, Caterson I, Zelissen P, et al. Topiramate: long-term maintenance of weight loss induced by a low-calorie diet in obese subjects. Obes Res 2004;12(10): 1658-69
    • (2004) Obes Res , vol.12 , Issue.10 , pp. 1658-1669
    • Astrup, A.1    Caterson, I.2    Zelissen, P.3
  • 138
    • 84861700104 scopus 로고    scopus 로고
    • Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures
    • Davalli AM, Perego C, Folli FB, Bosi E. Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures. Acta Diabetol 2012; 49(1):75-9
    • (2012) Acta Diabetol , vol.49 , Issue.1 , pp. 75-79
    • Davalli, A.M.1    Perego, C.2    Folli, F.B.3    Bosi, E.4
  • 139
    • 39049146979 scopus 로고    scopus 로고
    • Topiramate and type 2 diabetes: An old wine in a new bottle
    • Khanna V, Arumugam S, Roy S, et al. Topiramate and type 2 diabetes: an old wine in a new bottle. Expert Opin Ther Targets 2008;12(1):81-90
    • (2008) Expert Opin Ther Targets , vol.12 , Issue.1 , pp. 81-90
    • Khanna, V.1    Arumugam, S.2    Roy, S.3
  • 140
    • 0041922327 scopus 로고    scopus 로고
    • Topiramate normalizes hippocampal NPY-LI in flinders sensitive line 'depressed' rats and upregulates NPY, galanin, and CRH-LI in the hypothalamus: Implications for mood-stabilizing and weight loss-inducing effects
    • Husum H, Van Kammen D, Termeer E, et al. Topiramate normalizes hippocampal NPY-LI in flinders sensitive line 'depressed' rats and upregulates NPY, galanin, and CRH-LI in the hypothalamus: implications for mood-stabilizing and weight loss-inducing effects. Neuropsychopharmacology 2003;28(7): 1292-9
    • (2003) Neuropsychopharmacology , vol.28 , Issue.7 , pp. 1292-1299
    • Husum, H.1    Van Kammen, D.2    Termeer, E.3
  • 141
    • 0033775875 scopus 로고    scopus 로고
    • Effect of topiramate on body weight and body composition of Osborne-Mendel rats fed a high-fat diet: Alterations in hormones, neuropeptide, and uncoupling-protein mRNAs
    • York DA, Singer L, Thomas S, Bray GA. Effect of topiramate on body weight and body composition of Osborne-Mendel rats fed a high-fat diet: alterations in hormones, neuropeptide, and uncoupling-protein mRNAs. Nutrition 2000;16(10):967-75
    • (2000) Nutrition , vol.16 , Issue.10 , pp. 967-975
    • York, D.A.1    Singer, L.2    Thomas, S.3    Bray, G.A.4
  • 142
    • 33846416927 scopus 로고    scopus 로고
    • The effect of topiramate on energy balance in obese men: A 6-month doubleblind randomized placebo-controlled study with a 6-month open-label extension
    • Tremblay A, Chaput JP, Berube-Parent S, et al. The effect of topiramate on energy balance in obese men: a 6-month doubleblind randomized placebo-controlled study with a 6-month open-label extension. Eur J Clin Pharmacol 2007;63(2):123-34
    • (2007) Eur J Clin Pharmacol , vol.63 , Issue.2 , pp. 123-134
    • Tremblay, A.1    Chaput, J.P.2    Berube-Parent, S.3
  • 143
    • 70350757186 scopus 로고    scopus 로고
    • Changes of body weight and galanin in epileptic children treated with topiramate
    • Shi RF, Wang KL, Li QH, et al. Changes of body weight and galanin in epileptic children treated with topiramate. Zhonghua Er Ke Za Zhi 2007;45(3):199-202
    • (2007) Zhonghua Er Ke Za Zhi , vol.45 , Issue.3 , pp. 199-202
    • Shi, R.F.1    Wang, K.L.2    Li, Q.H.3
  • 144
    • 53449099067 scopus 로고    scopus 로고
    • A prospective study of body weight and serum leptin levels in patients treated with topiramate
    • Theisen FM, Beyenburg S, Gebhardt S, et al. A prospective study of body weight and serum leptin levels in patients treated with topiramate. Clin Neuropharmacol 2008;31(4):226-30
    • (2008) Clin Neuropharmacol , vol.31 , Issue.4 , pp. 226-230
    • Theisen, F.M.1    Beyenburg, S.2    Gebhardt, S.3
  • 145
    • 33748462442 scopus 로고    scopus 로고
    • The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment
    • Liang Y, She P, Wang X, Demarest K. The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment. Metabolism 2006;55(10):1411-19
    • (2006) Metabolism , vol.55 , Issue.10 , pp. 1411-1419
    • Liang, Y.1    She, P.2    Wang, X.3    Demarest, K.4
  • 147
    • 53949119583 scopus 로고    scopus 로고
    • Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats
    • Wallingford NM, Sinnayah P, Bymaster FP, et al. Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats. Neuropsychopharmacology 2008;33(12): 2922-33
    • (2008) Neuropsychopharmacology , vol.33 , Issue.12 , pp. 2922-2933
    • Wallingford, N.M.1    Sinnayah, P.2    Bymaster, F.P.3
  • 148
    • 84866236471 scopus 로고    scopus 로고
    • Pharmacological management of binge eating disorder: Current and emerging treatment options
    • McElroy SL, Guerdjikova AI, Mori N, O'Melia AM. Pharmacological management of binge eating disorder: current and emerging treatment options. Ther Clin Risk Manag 2012;8:219-41
    • (2012) Ther Clin Risk Manag , vol.8 , pp. 219-241
    • McElroy, S.L.1    Guerdjikova, A.I.2    Mori, N.3    O'melia, A.M.4
  • 149
    • 84869118179 scopus 로고    scopus 로고
    • Zonisamide for weight reduction in obese adults: A 1-year randomized controlled trial
    • Gadde KM, Kopping MF, Wagner HR 2nd, et al. Zonisamide for weight reduction in obese adults: a 1-year randomized controlled trial. Arch Intern Med 2012;172(20): 1557-15564
    • (2012) Arch Intern Med , vol.172 , Issue.20 , pp. 1557-15564
    • Gadde, K.M.1    Kopping, M.F.2    Wagner, H.R.3
  • 150
    • 84862799400 scopus 로고    scopus 로고
    • Low serum leptin level is associated with zonisamide-induced weight loss in overweight female epilepsy patients
    • Kim DW, Yoo MW, Park KS. Low serum leptin level is associated with zonisamide-induced weight loss in overweight female epilepsy patients. Epilepsy Behav 2012;23(4):497-9
    • (2012) Epilepsy Behav , vol.23 , Issue.4 , pp. 497-499
    • Kim, D.W.1    Yoo, M.W.2    Park, K.S.3
  • 152
    • 84856332005 scopus 로고    scopus 로고
    • Weight-reducing side effects of the antiepileptic agents topiramate and zonisamide
    • Antel J, Hebebrand J. Weight-reducing side effects of the antiepileptic agents topiramate and zonisamide. Handb Exp Pharmacol 2012;209:433-66
    • (2012) Handb Exp Pharmacol , vol.209 , pp. 433-466
    • Antel, J.1    Hebebrand, J.2
  • 153
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman PG. Obesity as a medical problem. Nature 2000;404(6778):635-43
    • (2000) Nature , vol.404 , Issue.6778 , pp. 635-643
    • Kopelman, P.G.1
  • 154
    • 0034917709 scopus 로고    scopus 로고
    • Impact of overweight on the risk of developing common chronic diseases during a 10-year period
    • Field AE, Coakley EH, Must A, et al. Impact of overweight on the risk of developing common chronic diseases during a 10-year period. Arch Intern Med 2001; 161(13):1581-6
    • (2001) Arch Intern Med , vol.161 , Issue.13 , pp. 1581-1586
    • Field, A.E.1    Coakley, E.H.2    Must, A.3
  • 155
    • 0034956457 scopus 로고    scopus 로고
    • Plasma leptin is independently associated with the intima-media thickness of the common carotid artery
    • Ciccone M, Vettor R, Pannacciulli N, et al. Plasma leptin is independently associated with the intima-media thickness of the common carotid artery. Int J Obes Relat Metab Disord 2001;25(6):805-10
    • (2001) Int J Obes Relat Metab Disord , vol.25 , Issue.6 , pp. 805-810
    • Ciccone, M.1    Vettor, R.2    Pannacciulli, N.3
  • 156
    • 0035844031 scopus 로고    scopus 로고
    • Leptin enhances the calcification of vascular cells: Artery wall as a target of leptin
    • Parhami F, Tintut Y, Ballard A, et al. Leptin enhances the calcification of vascular cells: artery wall as a target of leptin. Circ Res 2001;88(9):954-60
    • (2001) Circ Res , vol.88 , Issue.9 , pp. 954-960
    • Parhami, F.1    Tintut, Y.2    Ballard, A.3


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