Ghrelin levels are reduced in prepubertal epileptic children under treatment with carbamazepine or valproic acid

Epilepsia

Volumn 51, Issue 2, 2010, Pages 312-315

  Prodam, Flavia ^a   Bellone, Simonetta ^a   Casara, Gianluca ^b   De Rienzo, Francesca ^a   Grassino, Erica C ^a   Bonsignori, Ilaria ^a   Demarchi, Irene ^a   Rapa, Anna ^a   Radetti, Giorgio ^b   Bona, Gianni ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b CENTRAL HOSPITAL OF BOLZANO   (Italy)

Author keywords

BMI; Children; Ghrelin; Human; Seizures

Indexed keywords

CARBAMAZEPINE; GHRELIN; VALPROIC ACID;

ARTICLE; BENIGN CHILDHOOD EPILEPSY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; PREPUBERTY; PRIORITY JOURNAL; SIDE EFFECT;

AGE FACTORS; ANTICONVULSANTS; BODY HEIGHT; BODY MASS INDEX; CARBAMAZEPINE; CHILD; DEPRESSION, CHEMICAL; EPILEPSY; FEMALE; GHRELIN; HUMANS; MALE; PUBERTY; STATISTICS, NONPARAMETRIC; VALPROIC ACID; WEIGHT GAIN;

EID: 75649084560     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2009.02307.x     Document Type: Article

References (12)

1. Aydin S. (2007) Are ghrelin levels really elevated in epileptic patients? Seizure 16:469.
2. Aydin S, Dag E, Ozkan Y, Erman F, Dagli AF, Kilic N, Sahin I, Karatas F, Yoldas T, Barim AO, Kendir Y (2009) Nesfatin-1 and ghrelin levels in serum and saliva of epileptic patients: hormonal changes can have a major effect on seizure disorders. Mol Cell Biochem. Published on line: 05-March-2009; doi: 10.1007/s11010.009.0073.x.
3. Berilgen MS, Mungen B, Ustundag B, Demir C. (2006) Serum ghrelin levels are enhanced in patients with epilepsy. Seizure 15:106-111.
4. Camurdan MO, Bideci A, Demirel F, Cinaz P. (2006) Serum ghrelin, IGF-I and IGFBP-3 levels in children with normal variant short stature. Endocr J 53:479-484.
5. Gallagher BB, Murvin A, Flanigin HF, King DW, Luney D. (1984) Pituitary and adrenal function in epileptic patients. Epilepsia 25:683-689.
6. Greco R, Latini G, Chiarelli F, Iannetti P, Verrotti A. (2005) Leptin, ghrelin, and adiponectin in epileptic patients treated with valproic acid. Neurology 65:1808-1809.
7. Gungor S, Yucel G, Akinci A, Tabel Y, Ozerol IH, Yologlu S. (2007) The role of ghrelin in weight gain and growth in epileptic children using valproate. J Child Neurol 22:1384-1388.
8. Morrell MJ. (2003) Reproductive and metabolic disorders in women with epilepsy. Epilepsia 44(Suppl 4):11-20.
9. Ness-Abramof R, Apovian CM. (2005) Drug-induced weight gain. Timely Top Med Cardiovasc Dis 9:E31.
10. Obay BD, Tasdemir E, Tumer C, Bilgin HM, Sermet A. (2007) Antiepileptic effects of ghrelin on pentylenetetrazole-induced seizures in rats. Peptides 28:1214-1219.
11. Stroud LM, O'Brien TJ, Jupp B, Wallengren C, Morris MJ. (2005) Neuropeptide Y suppresses absence seizures in a genetic rat model. Brain Res 1033:151-156.
12. van der Lely AJ, Tschop M, Heiman ML, Ghigo E. (2004) Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocr Rev 25:426-657.