The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury

Journal of Molecular and Cellular Cardiology

Volumn 78, Issue , 2015, Pages 23-34

  Ong, Sang Bing ^a   Samangouei, Parisa ^a   Kalkhoran, Siavash Beikoghli ^a   Hausenloy, Derek J ^a,b  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

Cardioprotection; Ischemic heart disease; Mitochondrial permeability transition pore; Myocardial infarction; Myocardial ischemia reperfusion injury

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BICARBONATE SODIUM COTRANSPORTER; CALCIUM ION; CYCLOPHILIN D; CYCLOSPORIN A; GLYCOGEN SYNTHASE KINASE 3BETA; HEXOKINASE; HEXOKINASE 2; LACTIC ACID; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOFUSIN 2; PHOSPHATE TRANSPORTER; PROTEIN BAK; PROTEIN BAX; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; SODIUM PROTON EXCHANGE PROTEIN; SUCCINIC ACID; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL; CARRIER PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

CALCIUM TRANSPORT; CELL DEATH; CELL PH; CELL STRUCTURE; CORONARY ARTERY BYPASS GRAFT; DOWN REGULATION; ENZYME ACTIVITY; HEART INFARCTION SIZE; HEART PROTECTION; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; ISCHEMIC POSTCONDITIONING; ISCHEMIC PRECONDITIONING; MEMBRANE RUPTURE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION SWELLING; MULTICENTER STUDY (TOPIC); MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REPERFUSION INJURY; REVIEW; SIGNAL TRANSDUCTION; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; HEART INFARCTION PREVENTION; HEART MITOCHONDRION; METABOLISM; MOLECULARLY TARGETED THERAPY; MYOCARDIAL REPERFUSION INJURY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR TARGETED THERAPY; MYOCARDIAL REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 84916631354     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2014.11.005     Document Type: Review

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