Inhibition of GSK3β by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion

Circulation

Volumn 117, Issue 21, 2008, Pages 2761-2768

  Gomez, Ludovic ^a   Paillard, Mélanie ^a   Thibault, Hélène ^a,b   Derumeaux, Geneviève ^a,b   Ovize, Michel ^a,b,c  

^a UNIVERSITÉ LYON 1   (France)

^b LOUIS PRADEL HOSPITAL   (France)

^c INSERM   (France)

Author keywords

Ischemia; Myocardial infarction; Reperfusion

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; CALCIUM ION; CYCLOSPORIN A; GLYCOGEN SYNTHASE KINASE 3BETA; TRIPHENYLTETRAZOLIUM; CARRIER PROTEIN; CYCLOSPORIN; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HEART INFARCTION; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MITOCHONDRIAL PERMEABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECTROFLUOROMETRY; STAINING; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG ANTAGONISM; ELECTRON MICROSCOPY; ENZYMOLOGY; GENETICS; HEART MUSCLE CELL; METABOLISM; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; PATHOLOGY; PHOSPHORYLATION; REPERFUSION INJURY; ULTRASTRUCTURE;

ANIMALS; CYCLOSPORINE; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; INDOLES; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALEIMIDES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; OXIDATIVE PHOSPHORYLATION; PHOSPHORYLATION;

EID: 44449133771     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.755066     Document Type: Article

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