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Volumn 101, Issue 1, 2014, Pages 57-68

Nitrite activates protein kinase A in normoxia to mediate mitochondrial fusion and tolerance to ischaemia/reperfusion

Author keywords

Ischaemia; Mitochondria; Nitrite nitrate; Pre conditioning; Protein kinase A

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; DYNAMIN RELATED PROTEIN 1; NITRITE; REACTIVE OXYGEN METABOLITE; REGULATOR PROTEIN; SUPEROXIDE; UNCLASSIFIED DRUG;

EID: 84891366915     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt224     Document Type: Article
Times cited : (75)

References (63)
  • 1
    • 20944446791 scopus 로고    scopus 로고
    • Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver
    • Duranski MR, Greer JJ, Dejam A, Jaganmohan S, Hogg N, LangstonWet al. Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. J Clin Invest 2005;115:1232-1240.
    • (2005) J Clin Invest , vol.115 , pp. 1232-1240
    • Duranski, M.R.1    Greer, J.J.2    Dejam, A.3    Jaganmohan, S.4    Hogg, N.5    Langston, W.6
  • 2
    • 33846663552 scopus 로고    scopus 로고
    • Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: Role for xanthine oxidoreductase
    • Tripatara P, Patel NS,Webb A, Rathod K, Lecomte FM, Mazzon E et al. Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase. J Am Soc Nephrol 2007;18:570-580.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 570-580
    • Tripatara, P.1    Patel Nswebb, A.2    Rathod, K.3    Lecomte, F.M.4    Mazzon, E.5
  • 3
    • 33750934803 scopus 로고    scopus 로고
    • Early intravenous infusion of sodium nitrite protects brain against in vivo ischemia-reperfusion injury
    • Jung KH,Chu K,KoSY, Lee ST, Sinn DI, ParkDKet al. Early intravenous infusion of sodium nitrite protects brain against in vivo ischemia-reperfusion injury. Stroke 2006;37: 2744-2750.
    • (2006) Stroke , vol.37 , pp. 2744-2750
    • Jung, K.H.1    Chu, K.2    Ko, S.Y.3    Lee, S.T.4    Sinn, D.I.5    Park, D.K.6
  • 4
    • 34250776600 scopus 로고    scopus 로고
    • Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics
    • Dezfulian C, Raat N, Shiva S, Gladwin MT. Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics. Cardiovasc Res 2007;75:327-338.
    • (2007) Cardiovasc Res , vol.75 , pp. 327-338
    • Dezfulian, C.1    Raat, N.2    Shiva, S.3    Gladwin, M.T.4
  • 5
    • 4544378255 scopus 로고    scopus 로고
    • Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage
    • Webb A, Bond R, McLean P, Uppal R, Benjamin N, Ahluwalia A. Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. Proc Natl Acad Sci USA 2004;101:13683-13688.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13683-13688
    • Webb, A.1    Bond, R.2    McLean, P.3    Uppal, R.4    Benjamin, N.5    Ahluwalia, A.6
  • 6
  • 7
    • 38849162730 scopus 로고    scopus 로고
    • The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics
    • Lundberg JO, Weitzberg E, Gladwin MT. The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov 2008;7:156-167.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 156-167
    • Lundberg, J.O.1    Weitzberg, E.2    Gladwin, M.T.3
  • 8
    • 46249130703 scopus 로고    scopus 로고
    • Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction
    • Gonzalez FM, Shiva S, Vincent PS, Ringwood LA, Hsu LY, Hon YY et al. Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction. Circulation 2008;117:2986-2994.
    • (2008) Circulation , vol.117 , pp. 2986-2994
    • Gonzalez, F.M.1    Shiva, S.2    Vincent, P.S.3    Ringwood, L.A.4    Hsu, L.Y.5    Hon, Y.Y.6
  • 10
    • 48249110926 scopus 로고    scopus 로고
    • Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury
    • Hendgen-Cotta UB, MerxMW, Shiva S, Schmitz J, Becher S, Klare JP et al. Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury. Proc Natl Acad Sci USA 2008;105:10256-10261.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10256-10261
    • Hendgen-Cotta, U.B.1    Merx, M.W.2    Shiva, S.3    Schmitz, J.4    Becher, S.5    Klare, J.P.6
  • 11
    • 33947728687 scopus 로고    scopus 로고
    • Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration
    • Shiva S, Huang Z, Grubina R, Sun J, Ringwood LA, MacArthur PH et al. Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration. Circ Res 2007;100:654-661.
    • (2007) Circ Res , vol.100 , pp. 654-661
    • Shiva, S.1    Huang, Z.2    Grubina, R.3    Sun, J.4    Ringwood, L.A.5    MacArthur, P.H.6
  • 12
    • 34250877421 scopus 로고    scopus 로고
    • Nitrite reductase function of deoxymyoglobin: Oxygen sensor and regulator of cardiac energetics and function
    • Rassaf T, Flogel U, Drexhage C, Hendgen-Cotta U, Kelm M, Schrader J. Nitrite reductase function of deoxymyoglobin: oxygen sensor and regulator of cardiac energetics and function. Circ Res 2007;100:1749-1754.
    • (2007) Circ Res , vol.100 , pp. 1749-1754
    • Rassaf, T.1    Flogel, U.2    Drexhage, C.3    Hendgen-Cotta, U.4    Kelm, M.5    Schrader, J.6
  • 13
    • 0035816582 scopus 로고    scopus 로고
    • Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction. Evaluation of its role in nitric oxide generation in anoxic tissues
    • Li H, Samouilov A, Liu X, Zweier JL. Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction. Evaluation of its role in nitric oxide generation in anoxic tissues. J Biol Chem 2001;276:24482-24489.
    • (2001) J Biol Chem , vol.276 , pp. 24482-24489
    • Li, H.1    Samouilov, A.2    Liu, X.3    Zweier, J.L.4
  • 14
    • 34548412578 scopus 로고    scopus 로고
    • Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer
    • Shiva S, Sack MN, Greer JJ, Duranski M, Ringwood LA, Burwell L et al. Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer. J Exp Med 2007;204:2089-2102.
    • (2007) J Exp Med , vol.204 , pp. 2089-2102
    • Shiva, S.1    Sack, M.N.2    Greer, J.J.3    Duranski, M.4    Ringwood, L.A.5    Burwell, L.6
  • 15
    • 67651070577 scopus 로고    scopus 로고
    • Dietary nitrate and nitrite modulate blood and organ nitrite and the cellular ischemic stress response
    • Raat NJ, NoguchiAC, Liu VB, Raghavachari N, Liu D,XuXet al. Dietary nitrate and nitrite modulate blood and organ nitrite and the cellular ischemic stress response. Free Radic Biol Med 2009;47:510-517.
    • (2009) Free Radic Biol Med , vol.47 , pp. 510-517
    • Raat, N.J.1    Noguchiac Liu, V.B.2    Raghavachari, N.3    Liu, D.4    Xu, X.5
  • 16
  • 17
    • 62249218915 scopus 로고    scopus 로고
    • Cardioprotection and altered mitochondrial adenine nucleotide transport
    • Steenbergen C, Das S, Su J,Wong R, Murphy E. Cardioprotection and altered mitochondrial adenine nucleotide transport. Basic Res Cardiol 2009;104:149-156.
    • (2009) Basic Res Cardiol , vol.104 , pp. 149-156
    • Steenbergen, C.1    Das, S.2    Su, J.3    Wong, R.4    Murphy, E.5
  • 18
    • 1542619253 scopus 로고    scopus 로고
    • Cardiac preconditioning by volatile anesthetic agents: A defining role for altered mitochondrial bioenergetics
    • Stowe DF, Kevin LG. Cardiac preconditioning by volatile anesthetic agents: a defining role for altered mitochondrial bioenergetics. Antioxid Redox Signal 2004;6:439-448.
    • (2004) Antioxid Redox Signal , vol.6 , pp. 439-448
    • Stowe, D.F.1    Kevin, L.G.2
  • 19
    • 0141505088 scopus 로고    scopus 로고
    • Adenosine and cardioprotection during reperfusion-an overview
    • Donato M, Gelpi RJ. Adenosine and cardioprotection during reperfusion-an overview. Mol Cell Biochem 2003;251:153-159.
    • (2003) Mol Cell Biochem , vol.251 , pp. 153-159
    • Donato, M.1    Gelpi, R.J.2
  • 20
    • 0032541173 scopus 로고    scopus 로고
    • Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes
    • Vanden Hoek TL, Becker LB, Shao Z, Li C, Schumacker PT. Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes. J Biol Chem 1998;273:18092-18098.
    • (1998) J Biol Chem , vol.273 , pp. 18092-18098
    • Vanden Hoek, T.L.1    Becker, L.B.2    Shao, Z.3    Li, C.4    Schumacker, P.T.5
  • 21
    • 77958501463 scopus 로고    scopus 로고
    • Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase
    • Zmijewski JW, Banerjee S, Bae H, Friggeri A, Lazarowski ER, Abraham E. Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase. J Biol Chem 2010;285:33154-33164.
    • (2010) J Biol Chem , vol.285 , pp. 33154-33164
    • Zmijewski, J.W.1    Banerjee, S.2    Bae, H.3    Friggeri, A.4    Lazarowski, E.R.5    Abraham, E.6
  • 22
    • 80655145900 scopus 로고    scopus 로고
    • Lung cell hypoxia: Role of mitochondrial reactive oxygen species signaling in triggering responses
    • Schumacker PT. Lung cell hypoxia: role of mitochondrial reactive oxygen species signaling in triggering responses. Proc Am Thorac Soc 2011;8:477-484.
    • (2011) Proc Am Thorac Soc , vol.8 , pp. 477-484
    • Schumacker, P.T.1
  • 23
    • 81355133169 scopus 로고    scopus 로고
    • Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia
    • Kim H, Scimia MC, Wilkinson D, Trelles RD,Wood MR, Bowtell D et al. Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia. Mol Cell 2011;44:532-544.
    • (2011) Mol Cell , vol.44 , pp. 532-544
    • Kim, H.1    Scimia, M.C.2    Wilkinson, D.3    Trelles, R.D.4    Wood, M.R.5    Bowtell, D.6
  • 24
    • 80155137546 scopus 로고    scopus 로고
    • PKA/AKAP1 and PP2A/Bbeta2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics
    • Dickey AS, Strack S. PKA/AKAP1 and PP2A/Bbeta2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. J Neurosci 2011;31: 15716-15726.
    • (2011) J Neurosci , vol.31 , pp. 15716-15726
    • Dickey, A.S.1    Strack, S.2
  • 25
  • 26
    • 33644876126 scopus 로고    scopus 로고
    • Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase)
    • Lecour S, Suleman N, Deuchar GA, Somers S, Lacerda L, Huisamen B et al. Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase). Circulation 2005;112:3911-3918.
    • (2005) Circulation , vol.112 , pp. 3911-3918
    • Lecour, S.1    Suleman, N.2    Deuchar, G.A.3    Somers, S.4    Lacerda, L.5    Huisamen, B.6
  • 27
    • 0034616164 scopus 로고    scopus 로고
    • Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis
    • Stephanou A, Brar BK, Scarabelli TM, Jonassen AK, Yellon DM, Marber MS et al. Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis. J Biol Chem 2000;275:10002-10008.
    • (2000) J Biol Chem , vol.275 , pp. 10002-10008
    • Stephanou, A.1    Brar, B.K.2    Scarabelli, T.M.3    Jonassen, A.K.4    Yellon, D.M.5    Marber, M.S.6
  • 28
    • 45849120527 scopus 로고    scopus 로고
    • Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning
    • Suleman N, Somers S, Smith R, Opie LH, Lecour SC. Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning. Cardiovasc Res 2008;79: 127-133.
    • (2008) Cardiovasc Res , vol.79 , pp. 127-133
    • Suleman, N.1    Somers, S.2    Smith, R.3    Opie, L.H.4    Lecour, S.C.5
  • 29
    • 84865619201 scopus 로고    scopus 로고
    • Nitrite activatesAMPkinase to stimulate mitochondrial biogenesis independent of soluble guanylate cyclase
    • MoL,Wang Y, Geary L, CoreyC, Alef MJ, Beer-StolzDet al. Nitrite activatesAMPkinase to stimulate mitochondrial biogenesis independent of soluble guanylate cyclase. Free Radic Biol Med 2012;53:1440-1450.
    • (2012) Free Radic Biol Med , vol.53 , pp. 1440-1450
    • Mo, L.1    Wang, Y.2    Geary, L.3    Corey, C.4    Alef, M.J.5    Beer-Stolz, D.6
  • 30
    • 0028075773 scopus 로고
    • Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs
    • Gardner PR, Nguyen DD, White CW. Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs. Proc Natl Acad Sci USA 1994;91:12248-12252.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12248-12252
    • Gardner, P.R.1    Nguyen, D.D.2    White, C.W.3
  • 32
    • 34848840991 scopus 로고    scopus 로고
    • Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death
    • Cribbs JT, Strack S. Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death. EMBO Rep 2007;8:939-944.
    • (2007) EMBO Rep , vol.8 , pp. 939-944
    • Cribbs, J.T.1    Strack, S.2
  • 33
    • 40949098241 scopus 로고    scopus 로고
    • Copper dependence of the biotin switch assay: Modified assay for measuring cellular and blood nitrosated proteins
    • Wang X, Kettenhofen NJ, Shiva S, Hogg N, Gladwin MT. Copper dependence of the biotin switch assay: modified assay for measuring cellular and blood nitrosated proteins. Free Radic Biol Med 2008;44:1362-1372.
    • (2008) Free Radic Biol Med , vol.44 , pp. 1362-1372
    • Wang, X.1    Kettenhofen, N.J.2    Shiva, S.3    Hogg, N.4    Gladwin, M.T.5
  • 35
    • 4043087772 scopus 로고    scopus 로고
    • Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection
    • Hausenloy D, Wynne A, Duchen M, Yellon D. Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection. Circulation 2004;109:1714-1717.
    • (2004) Circulation , vol.109 , pp. 1714-1717
    • Hausenloy, D.1    Wynne, A.2    Duchen, M.3    Yellon, D.4
  • 36
    • 81155128499 scopus 로고    scopus 로고
    • Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease
    • Dagda RK, Gusdon AM, Pien I, Strack S, Green S, LiCet al. Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease. Cell Death Differ 2011;18:1914-1923.
    • (2011) Cell Death Differ , vol.18 , pp. 1914-1923
    • Dagda, R.K.1    Gusdon, A.M.2    Pien, I.3    Strack, S.4    Green, S.5    Li, C.6
  • 37
    • 0034711508 scopus 로고    scopus 로고
    • The late phase of preconditioning
    • Bolli R. The late phase of preconditioning. Circ Res 2000;87:972-983.
    • (2000) Circ Res , vol.87 , pp. 972-983
    • Bolli, R.1
  • 39
    • 77956795824 scopus 로고    scopus 로고
    • Mitochondrial morphology and cardiovascular disease
    • Ong SB, Hausenloy DJ. Mitochondrial morphology and cardiovascular disease. Cardiovasc Res 2010;88:16-29.
    • (2010) Cardiovasc Res , vol.88 , pp. 16-29
    • Ong, S.B.1    Hausenloy, D.J.2
  • 40
    • 0037424239 scopus 로고    scopus 로고
    • Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
    • Olichon A, Baricault L, Gas N, Guillou E, Valette A, Belenguer P et al. Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J Biol Chem 2003;278:7743-7746.
    • (2003) J Biol Chem , vol.278 , pp. 7743-7746
    • Olichon, A.1    Baricault, L.2    Gas, N.3    Guillou, E.4    Valette, A.5    Belenguer, P.6
  • 41
    • 0037593949 scopus 로고    scopus 로고
    • Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity
    • Bach D, Pich S, Soriano FX, Vega N, Baumgartner B, Oriola J et al. Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. J Biol Chem 2003;278:17190-17197.
    • (2003) J Biol Chem , vol.278 , pp. 17190-17197
    • Bach, D.1    Pich, S.2    Soriano, F.X.3    Vega, N.4    Baumgartner, B.5    Oriola, J.6
  • 42
    • 20444461625 scopus 로고    scopus 로고
    • The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
    • Pich S, Bach D, Briones P, Liesa M, Camps M, Testar X et al. The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system. Hum Mol Genet 2005;14:1405-1415.
    • (2005) Hum Mol Genet , vol.14 , pp. 1405-1415
    • Pich, S.1    Bach, D.2    Briones, P.3    Liesa, M.4    Camps, M.5    Testar, X.6
  • 43
    • 39549092137 scopus 로고    scopus 로고
    • AMP-activated protein kinase conducts the ischemic stress response orchestra
    • Young LH. AMP-activated protein kinase conducts the ischemic stress response orchestra. Circulation 2008;117:832-840.
    • (2008) Circulation , vol.117 , pp. 832-840
    • Young, L.H.1
  • 45
    • 84864124772 scopus 로고    scopus 로고
    • AMPKactivation stimulates autophagy and ameliorates muscular dystrophy in the mdx mouse diaphragm
    • Pauly M, Daussin F, BurelleY, Li T, Godin R, Fauconnier J et al.AMPKactivation stimulates autophagy and ameliorates muscular dystrophy in the mdx mouse diaphragm.AmJ Pathol 2012;181:583-592.
    • (2012) Am J Pathol , vol.181 , pp. 583-592
    • Pauly, M.1    Daussin, F.2    Burelley Li, T.3    Godin, R.4    Fauconnier, J.5
  • 46
    • 64149129154 scopus 로고    scopus 로고
    • Effects of nitrite on modulating ROS generation following ischemia and reperfusion
    • Raat NJ, Shiva S, Gladwin MT. Effects of nitrite on modulating ROS generation following ischemia and reperfusion. Adv Drug Deliv Rev 2009;61:339-350.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 339-350
    • Raat, N.J.1    Shiva, S.2    Gladwin, M.T.3
  • 47
    • 0030909465 scopus 로고    scopus 로고
    • Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide-dependent toxicity
    • van der Vliet A, Eiserich JP, Halliwell B, Cross CE. Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide-dependent toxicity. J Biol Chem 1997;272:7617-7625.
    • (1997) J Biol Chem , vol.272 , pp. 7617-7625
    • Van Der Vliet, A.1    Eiserich, J.P.2    Halliwell, B.3    Cross, C.E.4
  • 48
    • 84861318584 scopus 로고    scopus 로고
    • Normoxic cyclicGMP-independent oxidative signaling by nitrite enhances airway epithelial cell proliferation and wound healing
    • Wang L, Frizzell SA, Zhao X, GladwinMT. Normoxic cyclicGMP-independent oxidative signaling by nitrite enhances airway epithelial cell proliferation and wound healing. Nitric Oxide 2012;26:203-210.
    • (2012) Nitric Oxide , vol.26 , pp. 203-210
    • Wang, L.1    Frizzell, S.A.2    Zhao, X.3    Gladwin, M.T.4
  • 49
    • 18544380386 scopus 로고    scopus 로고
    • Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP
    • Coles B, BloodsworthA, Eiserich JP, Coffey MJ, McLoughlin RM, Giddings JC et al. Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP. J Biol Chem 2002;277:5832-5840.
    • (2002) J Biol Chem , vol.277 , pp. 5832-5840
    • Coles, B.1    Bloodsworth, A.2    Eiserich, J.P.3    Coffey, M.J.4    McLoughlin, R.M.5    Giddings, J.C.6
  • 50
    • 64249093838 scopus 로고    scopus 로고
    • Mechanistic insights into nitrite-induced cardioprotection using an integrated metabolomic/proteomic approach
    • Perlman DH, Bauer SM, Ashrafian H, Bryan NS, Garcia-Saura MF, Lim CC et al. Mechanistic insights into nitrite-induced cardioprotection using an integrated metabolomic/proteomic approach. Circ Res 2009;104:796-804.
    • (2009) Circ Res , vol.104 , pp. 796-804
    • Perlman, D.H.1    Bauer, S.M.2    Ashrafian, H.3    Bryan, N.S.4    Garcia-Saura, M.F.5    Lim, C.C.6
  • 51
    • 76749112482 scopus 로고    scopus 로고
    • Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxidedependent pathway
    • Venkatesh PK, Pattillo CB, Branch B, Hood J, Thoma S, Illum S et al. Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxidedependent pathway. Cardiovasc Res 2010;85:661-670.
    • (2010) Cardiovasc Res , vol.85 , pp. 661-670
    • Venkatesh, P.K.1    Pattillo, C.B.2    Branch, B.3    Hood, J.4    Thoma, S.5    Illum, S.6
  • 52
    • 84855462583 scopus 로고    scopus 로고
    • Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: Role of nitric oxide and reactive oxygen species
    • Giedt RJ, Yang C, Zweier JL, Matzavinos A, Alevriadou BR. Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: role of nitric oxide and reactive oxygen species. Free Radic Biol Med 2012;52:348-356.
    • (2012) Free Radic Biol Med , vol.52 , pp. 348-356
    • Giedt, R.J.1    Yang, C.2    Zweier, J.L.3    Matzavinos, A.4    Alevriadou, B.R.5
  • 53
    • 21644455319 scopus 로고    scopus 로고
    • Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization
    • Neuspiel M, Zunino R, Gangaraju S, Rippstein P, McBride H. Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization. J Biol Chem 2005;280:25060-25070.
    • (2005) J Biol Chem , vol.280 , pp. 25060-25070
    • Neuspiel, M.1    Zunino, R.2    Gangaraju, S.3    Rippstein, P.4    McBride, H.5
  • 54
    • 33845384841 scopus 로고    scopus 로고
    • AMP-activated protein kinase mediates preconditioning in cardiomyocytes by regulating activity and trafficking of sarcolemmalATP-sensitive K(+) channels
    • Sukhodub A, Jovanovic S, Du Q, Budas G, Clelland AK, Shen M et al. AMP-activated protein kinase mediates preconditioning in cardiomyocytes by regulating activity and trafficking of sarcolemmalATP-sensitive K(+) channels. J Cell Physiol 2007;210:224-236.
    • (2007) J Cell Physiol , vol.210 , pp. 224-236
    • Sukhodub, A.1    Jovanovic, S.2    Du, Q.3    Budas, G.4    Clelland, A.K.5    Shen, M.6
  • 55
    • 43949114864 scopus 로고    scopus 로고
    • Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion
    • Matsui Y, Kyoi S, Takagi H, Hsu CP, Hariharan N, Ago T et al. Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion. Autophagy 2008;4:409-415.
    • (2008) Autophagy , vol.4 , pp. 409-415
    • Matsui, Y.1    Kyoi, S.2    Takagi, H.3    Hsu, C.P.4    Hariharan, N.5    Ago, T.6
  • 56
    • 34147168105 scopus 로고    scopus 로고
    • Distinct roles of autophagy in the heart during ischemia and reperfusion: Roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
    • Matsui Y, Takagi H, Qu X, Abdellatif M, Sakoda H, Asano T et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circulation Res 2007;100:914-922.
    • (2007) Circulation Res , vol.100 , pp. 914-922
    • Matsui, Y.1    Takagi, H.2    Qu, X.3    Abdellatif, M.4    Sakoda, H.5    Asano, T.6
  • 57
    • 0141960109 scopus 로고    scopus 로고
    • AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells
    • Lee M, Hwang JT, Lee HJ, Jung SN, Kang I, Chi SG et al. AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells. J Biol Chem 2003;278: 39653-39661.
    • (2003) J Biol Chem , vol.278 , pp. 39653-39661
    • Lee, M.1    Hwang, J.T.2    Lee, H.J.3    Jung, S.N.4    Kang, I.5    Chi, S.G.6
  • 58
    • 41849094797 scopus 로고    scopus 로고
    • Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells
    • Jung SN, Yang WK, Kim J, Kim HS, Kim EJ, Yun H et al. Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells. Carcinogenesis 2008;29:713-721.
    • (2008) Carcinogenesis , vol.29 , pp. 713-721
    • Jung, S.N.1    Yang, W.K.2    Kim, J.3    Kim, H.S.4    Kim, E.J.5    Yun, H.6
  • 59
    • 70349783069 scopus 로고    scopus 로고
    • Reactive oxygen species-induced stimulation of 5?AMP-activated protein kinase mediates sevoflurane-induced cardioprotection
    • Lamberts RR, Onderwater G, Hamdani N, Vreden MJ, Steenhuisen J, Eringa EC et al. Reactive oxygen species-induced stimulation of 5?AMP-activated protein kinase mediates sevoflurane-induced cardioprotection. Circulation 2009;120:S10-15.
    • (2009) Circulation , vol.120
    • Lamberts, R.R.1    Onderwater, G.2    Hamdani, N.3    Vreden, M.J.4    Steenhuisen, J.5    Eringa, E.C.6
  • 60
    • 33744514139 scopus 로고    scopus 로고
    • Identification and characterization of a small moleculeAMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
    • Cool B, Zinker B, ChiouW, Kifle L, Cao N, PerhamMet al. Identification and characterization of a small moleculeAMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metab 2006;3:403-416.
    • (2006) Cell Metab , vol.3 , pp. 403-416
    • Cool, B.1    Zinker, B.2    Chiouw Kifle, L.3    Cao, N.4    Perham, M.5
  • 61
    • 78751554136 scopus 로고    scopus 로고
    • Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation
    • Konishi M, Haraguchi G, Ohigashi H, Ishihara T, Saito K, Nakano Yet al. Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation. Cardiovasc Res 2011;89:309-319.
    • (2011) Cardiovasc Res , vol.89 , pp. 309-319
    • Konishi, M.1    Haraguchi, G.2    Ohigashi, H.3    Ishihara, T.4    Saito, K.5    Nakano, Y.6
  • 62
    • 79956066326 scopus 로고    scopus 로고
    • Dietary nitrate supplementation protects against Doxorubicin-induced cardiomyopathy by improving mitochondrial function
    • Zhu SG, Kukreja RC, Das A, Chen Q, Lesnefsky EJ, Xi L. Dietary nitrate supplementation protects against Doxorubicin-induced cardiomyopathy by improving mitochondrial function. J Am Coll Cardiol 2011;57:2181-2189.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 2181-2189
    • Zhu, S.G.1    Kukreja, R.C.2    Das, A.3    Chen, Q.4    Lesnefsky, E.J.5    Xi, L.6
  • 63
    • 78049238308 scopus 로고    scopus 로고
    • Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice
    • Carlstrom M, Larsen FJ, Nystrom T, Hezel M, Borniquel S,Weitzberg E et al. Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice. Proc Natl Acad Sci USA 2010;107:17716-17720.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 17716-17720
    • Carlstrom, M.1    Larsen, F.J.2    Nystrom, T.3    Hezel, M.4    Borniquel, S.5    Weitzberg, E.6


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