SIRT3 protects cells from hypoxia via PGC-1α- and MnSOD-dependent pathways

Neuroscience

Volumn 286, Issue , 2015, Pages 109-121

  Wang, Q ^a   Li, L ^a   Li, C Y ^a   Pei, Z ^a   Zhou, M ^a   Li, N ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Manganese superoxide dismutase; Oxygen glucose deprivation; Peroxisome proliferator activated receptor coactivator 1 ; Reactive oxygen species; Silent information regulation 2 homolog 3

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; LACTATE DEHYDROGENASE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RECOMBINANT PROTEIN; SIRTUIN 3; SMALL INTERFERING RNA; PPARGC1A PROTEIN, RAT; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR;

ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DISEASE EXACERBATION; DOWN REGULATION; ENZYME RELEASE; GENE SILENCING; IN VITRO STUDY; MANGANESE SUPEROXIDE DISMUTASE GENE; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL; NEUROPROTECTION; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA GENE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIRT3 GENE; UPREGULATION; ANIMAL; ANOXIA; CELL CULTURE; CELL SURVIVAL; DISEASE MODEL; METABOLISM; PC12 CELL LINE; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANOXIA; BRAIN ISCHEMIA; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; PC12 CELLS; RATS; SIGNAL TRANSDUCTION; SIRTUIN 3; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS;

EID: 84916624768     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.11.045     Document Type: Article

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