Icariin protects against brain injury by enhancing SIRT1-dependent PGC-1α Expression in experimental stroke

Neuropharmacology

Volumn 59, Issue 1-2, 2010, Pages 70-76

  Zhu, Hai rong ^a   Wang, Zhong yuan ^a,b,c   Zhu, Xiao lei ^a   Wu, Xiao xin ^a   Li, Er guang ^b,d   Xu, Yun ^a,b,c  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b NANJING UNIVERSITY   (China)

^c THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^d MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Icariin; Ischemic stroke; Neuroprotection; PGC 1 ; SIRT1

Indexed keywords

ICARIIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SIRTUIN 1; FLAVONOID; NEUROPROTECTIVE AGENT; PPARGC1A PROTEIN, MOUSE; SIRT1 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN FUNCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL VIABILITY; CONTROLLED STUDY; DENSITOMETRY; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MORTALITY; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; STROKE; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BRAIN; BRAIN EDEMA; BRAIN INJURIES; CELL SURVIVAL; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; INFARCTION, MIDDLE CEREBRAL ARTERY; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY; RANDOMIZATION;

ANIMALS; APOPTOSIS; BRAIN; BRAIN EDEMA; BRAIN INJURIES; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; NEURONS; NEUROPROTECTIVE AGENTS; RANDOM ALLOCATION; SIRTUIN 1; STROKE; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 77953285783     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.03.017     Document Type: Article

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