Protective effects of pioglitazone and/or liraglutide on pancreatic β-cells in db/db mice: Comparison of their effects between in an early and advanced stage of diabetes

Molecular and Cellular Endocrinology

Volumn 400, Issue , 2015, Pages 78-89

  Kimura, Tomohiko ^a   Kaneto, Hideaki ^a   Shimoda, Masashi ^a   Hirukawa, Hidenori ^a   Okauchi, Seizo ^a   Kohara, Kenji ^a   Hamamoto, Sumiko ^a   Tawaramoto, Kazuhito ^a   Hashiramoto, Mitsuru ^b   Kaku, Kohei ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

^b YODOGAWA CHRISTIAN HOSPITAL   (Japan)

Author keywords

Cellular kinetics; Liraglutide; Pioglitazone; Progression of diabetic morbidity; Cell

Indexed keywords

CASPASE 3; CASPASE 8; COLLAGEN TYPE 1; COLLAGEN TYPE 3; GLUCAGON LIKE PEPTIDE 1; GLUCOKINASE; GLUCOSE REGULATED PROTEIN 78; GLUCOSE TRANSPORTER 2; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INSULIN; LIRAGLUTIDE; NEUROGENIC DIFFERENTIATION FACTOR; PIOGLITAZONE; PROTEIN BCL 2; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1; TRIACYLGLYCEROL; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; BCL2 PROTEIN, MOUSE; CASPASE; GLUCAGON; GLUCOSE BLOOD LEVEL; KI 67 ANTIGEN; RNA 18S;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE COURSE; GENE EXPRESSION; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SYNTHESIS; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; COMPARATIVE STUDY; DIABETES MELLITUS, TYPE 2; DISEASE MODEL; DRUG EFFECTS; GENETICS; GLUCOSE BLOOD LEVEL; METABOLISM; ORGAN SIZE; PATHOLOGY; TIME; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CASPASES; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE EXPRESSION; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; KI-67 ANTIGEN; MALE; MICE; MICE, TRANSGENIC; ORGAN SIZE; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, RIBOSOMAL, 18S; THIAZOLIDINEDIONES; TIME FACTORS; TRIGLYCERIDES;

EID: 84913568797     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2014.11.018     Document Type: Article

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